Kenneth Hugh Mayer

Summary

Affiliation: Brown University
Country: USA

Publications

  1. pmc Comparison of patient comprehension of rapid HIV pre-test fundamentals by information delivery format in an emergency department setting
    Roland C Merchant
    Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA
    BMC Public Health 7:238. 2007
  2. ncbi request reprint Persistence of human immunodeficiency virus in semen after adding indinavir to combination antiretroviral therapy
    K H Mayer
    Fenway Community Health Center, Brigham and Women s Hospital, Massachusetts General Hospital, and Harvard Medical School, Boston, USA
    Clin Infect Dis 28:1252-9. 1999
  3. doi request reprint The social ecology of HIV/AIDS
    Kenneth Mayer
    Brown University, 164 Summit Avenue, Providence, RI 02906, USA
    Med Clin North Am 92:1363-75, x. 2008
  4. pmc Which HIV-infected men who have sex with men in care are engaging in risky sex and acquiring sexually transmitted infections: findings from a Boston community health centre
    K H Mayer
    The Fenway Institute, Fenway Health, 1340 Boylston Street, Boston, MA 02215, USA
    Sex Transm Infect 86:66-70. 2010
  5. pmc Sexual and gender minority health: what we know and what needs to be done
    Kenneth H Mayer
    Infectious Diseases Division, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, USA
    Am J Public Health 98:989-95. 2008
  6. doi request reprint Tenofovir DF plus lamivudine or emtricitabine for nonoccupational postexposure prophylaxis (NPEP) in a Boston Community Health Center
    Kenneth H Mayer
    Fenway Institute, Fenway Community Health, Boston, MA, USA
    J Acquir Immune Defic Syndr 47:494-9. 2008
  7. ncbi request reprint HIV care providers and prevention: opportunities and challenges
    Kenneth H Mayer
    Infectious Disease Division, Department of Medicine, Brown University The Miriam Hospital, Providence, RI 02906, USA
    J Acquir Immune Defic Syndr 37:S130-2. 2004
  8. ncbi request reprint Supporting clinical research: a unique catalyst--the remarkable legacy of Dr. Mathilde Krim
    Kenneth H Mayer
    Brown University AIDS Program, Infectious Diseases, Miriam Hospital, 164 Summit Avenue, Providence, Rhode Island 02906, USA
    AIDS Patient Care STDS 20:476-9. 2006
  9. ncbi request reprint Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women
    Kenneth H Mayer
    Miriam Hospital Brown University, Providence, Rhode Island 02906, USA
    AIDS 20:543-51. 2006
  10. ncbi request reprint Clinical and immunologic progression in HIV-infected US women before and after the introduction of highly active antiretroviral therapy
    Kenneth H Mayer
    Miriam Hospital and dagger Brown University, Providence, Rhode Island 02906, USA
    J Acquir Immune Defic Syndr 33:614-24. 2003

Research Grants

  1. Enhancing HIV Prevention Among High-Risk HIV+ Men
    Kenneth Mayer; Fiscal Year: 2007
  2. HIV PREVENTION TRIAL UNITS
    Kenneth Mayer; Fiscal Year: 2007

Detail Information

Publications105 found, 100 shown here

  1. pmc Comparison of patient comprehension of rapid HIV pre-test fundamentals by information delivery format in an emergency department setting
    Roland C Merchant
    Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA
    BMC Public Health 7:238. 2007
    ..Two trials were conducted to compare emergency department patient comprehension of rapid HIV pre-test information using different methods to deliver this information...
  2. ncbi request reprint Persistence of human immunodeficiency virus in semen after adding indinavir to combination antiretroviral therapy
    K H Mayer
    Fenway Community Health Center, Brigham and Women s Hospital, Massachusetts General Hospital, and Harvard Medical School, Boston, USA
    Clin Infect Dis 28:1252-9. 1999
    ..HIV-1 protease inhibitor resistance mutants may emerge in the semen of patients receiving combination therapy...
  3. doi request reprint The social ecology of HIV/AIDS
    Kenneth Mayer
    Brown University, 164 Summit Avenue, Providence, RI 02906, USA
    Med Clin North Am 92:1363-75, x. 2008
    ..The epidemic continues to grow despite effective treatment because of the absence of a protective vaccine and the continuation of high risk sexual behavior and substance use...
  4. pmc Which HIV-infected men who have sex with men in care are engaging in risky sex and acquiring sexually transmitted infections: findings from a Boston community health centre
    K H Mayer
    The Fenway Institute, Fenway Health, 1340 Boylston Street, Boston, MA 02215, USA
    Sex Transm Infect 86:66-70. 2010
    ....
  5. pmc Sexual and gender minority health: what we know and what needs to be done
    Kenneth H Mayer
    Infectious Diseases Division, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, USA
    Am J Public Health 98:989-95. 2008
    ..We then discuss how clinicians and public health professionals can improve research methods, clinical outcomes, and service delivery for lesbian, gay, bisexual, and transgender people...
  6. doi request reprint Tenofovir DF plus lamivudine or emtricitabine for nonoccupational postexposure prophylaxis (NPEP) in a Boston Community Health Center
    Kenneth H Mayer
    Fenway Institute, Fenway Community Health, Boston, MA, USA
    J Acquir Immune Defic Syndr 47:494-9. 2008
    ..Fenway Community Health, the largest center caring for HIV-infected and high-risk men who have sex with men (MSM) in New England, began an NPEP program in 1997, initially using zidovudine-based regimens...
  7. ncbi request reprint HIV care providers and prevention: opportunities and challenges
    Kenneth H Mayer
    Infectious Disease Division, Department of Medicine, Brown University The Miriam Hospital, Providence, RI 02906, USA
    J Acquir Immune Defic Syndr 37:S130-2. 2004
  8. ncbi request reprint Supporting clinical research: a unique catalyst--the remarkable legacy of Dr. Mathilde Krim
    Kenneth H Mayer
    Brown University AIDS Program, Infectious Diseases, Miriam Hospital, 164 Summit Avenue, Providence, Rhode Island 02906, USA
    AIDS Patient Care STDS 20:476-9. 2006
  9. ncbi request reprint Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women
    Kenneth H Mayer
    Miriam Hospital Brown University, Providence, Rhode Island 02906, USA
    AIDS 20:543-51. 2006
    ....
  10. ncbi request reprint Clinical and immunologic progression in HIV-infected US women before and after the introduction of highly active antiretroviral therapy
    Kenneth H Mayer
    Miriam Hospital and dagger Brown University, Providence, Rhode Island 02906, USA
    J Acquir Immune Defic Syndr 33:614-24. 2003
    ..To examine factors associated with clinical and immunologic HIV disease progression in a cohort of US women...
  11. ncbi request reprint Brown's Fogarty International Center AIDS International Research and Training Program: building capacity and new collaborations
    Kenneth H Mayer
    The Warren Alpert Medical School of Brown University, USA
    Med Health R I 90:342-5. 2007
  12. ncbi request reprint Safety and tolerability of BufferGel, a novel vaginal microbicide, in women in the United States
    K H Mayer
    Infectious Disease Division, Memorial Hospital of Rhode Island, Pawtucket, RI, USA
    Clin Infect Dis 32:476-82. 2001
    ....
  13. pmc The evolution of the Fenway Community Health model
    K Mayer
    Infectious Disease Division, Memorial Hospital of Rhode Island, 111 Brewster St, Pawtucket, RI 02860, USA
    Am J Public Health 91:892-4. 2001
    ..This health center may provide a model of comprehensive LGBT health services that have a local impact...
  14. pmc Chemoprophylaxis for HIV prevention: new opportunities and new questions
    Kenneth H Mayer
    Division of Infectious Diseases, Department of Medicine, and Department of Community Health, Alpert Medical School, Brown University, Miriam Hospital, Providence, RI 02906, USA
    J Acquir Immune Defic Syndr 55:S122-7. 2010
    ....
  15. doi request reprint Introduction: Linkage, engagement, and retention in HIV care: essential for optimal individual- and community-level outcomes in the era of highly active antiretroviral therapy
    Kenneth Hugh Mayer
    The Warren Alpert Medical School, Brown University, and The Miriam Hospital, Providence, Rhode Island 02906, USA
    Clin Infect Dis 52:S205-7. 2011
    ....
  16. pmc Interactions of HIV, other sexually transmitted diseases, and genital tract inflammation facilitating local pathogen transmission and acquisition
    Kenneth H Mayer
    Division of Infectious Diseases, Department of Medicine, Alpert Medical School, Brown University, Providence, RI 02906, USA
    Am J Reprod Immunol 65:308-16. 2011
    ....
  17. pmc Antiretroviral therapy as HIV prevention: status and prospects
    Kenneth H Mayer
    Alpert Medical School, Brown University, Providence, RI, USA
    Am J Public Health 100:1867-76. 2010
    ..It is possible that the life-saving agents that have transformed the natural history of AIDS can be a critical component of HIV prevention efforts, but their ultimate role in affecting HIV transmission dynamics remains to be defined...
  18. pmc HIV/AIDS and the Black Church: what are the barriers to prevention services?
    Justin Smith
    Department of Infectious Diseases, Miriam Hospital, Brown University, Providence, RI, USA
    J Natl Med Assoc 97:1682-5. 2005
    ..The aim of the current study was to understand the barriers to HIV/AIDS prevention services offered by black churches in a northeastern metropolitan area by surveying the ministers who lead the churches...
  19. pmc Clinical impact and cost-effectiveness of antiretroviral therapy in India: starting criteria and second-line therapy
    Kenneth A Freedberg
    Divisions of General Medicine and Infectious Disease and the Partners AIDS Research Center, Massachusetts General Hospital, Boston, MA, USA
    AIDS 21:S117-28. 2007
    ..India has more than 5.7 million people infected with human immunodeficiency virus (HIV). In 2004, the Indian government began providing antiretroviral therapy (ART), and there are now an estimated 56 500 people receiving ART...
  20. pmc The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
    Florencia Pereyra
    Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology MIT and Harvard, Boston, MA, USA
    Science 330:1551-7. 2010
    ..These results implicate the nature of the HLA-viral peptide interaction as the major factor modulating durable control of HIV infection...
  21. doi request reprint Drug use and other risk factors related to lower body mass index among HIV-infected individuals
    Lien A Quach
    Tufts University School of Medicine, Boston, MA 02111, USA
    Drug Alcohol Depend 95:30-6. 2008
    ..BMI was also directly associated with CD4 count and inversely related to age more than 55 years old. HIV-infected cocaine users may be at higher risk of developing malnutrition, suggesting the need for anticipatory nutritional support...
  22. pmc Cost-effectiveness of tenofovir as first-line antiretroviral therapy in India
    Melissa A Bender
    Divisions of General Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    Clin Infect Dis 50:416-25. 2010
    ..We evaluated the clinical outcomes and cost-effectiveness of first-line ART using tenofovir in India, compared with current practice using stavudine or zidovudine...
  23. ncbi request reprint Perceptions about the acceptability of assessments of HIV medication adherence in Lilongwe, Malawi and Chennai, India
    Steven A Safren
    Fenway Community Health, Research and Evaluation Department, Boston, Massachusetts 02215, USA
    AIDS Behav 10:443-50. 2006
    ..Innovative ways of monitoring adherence while maintaining standardization across sites are required in multisite trials...
  24. ncbi request reprint Partner-specific sexual behavioral differences between phase 3 HIV vaccine efficacy trial participants and controls: Project VISION
    William L H Whittington
    Department of Medicine, University of Washington, Seattle, WA 98104, USA
    J Acquir Immune Defic Syndr 43:234-8. 2006
    ..To assess and compare sexual behaviors using partner-specific data between HIV-negative men who have sex with men (MSM) recruited for an HIV vaccine efficacy trial and a control group...
  25. ncbi request reprint A survey of MSM HIV prevention outreach workers in Chennai, India
    Steven A Safren
    Fenway Community Health, Research and Evaluation Department, Boston, USA
    AIDS Educ Prev 18:323-32. 2006
    ..These data point to several important barriers to HIV prevention among MSM in South India and lay the groundwork for enhancing the use of outreach workers to play a role in HIV prevention in this population...
  26. ncbi request reprint Primary care issues for HIV-infected patients
    Daniel E Cohen
    The Fenway Institute, Fenway Community Health, 7 Haviland Street, Boston, MA 02115, USA
    Infect Dis Clin North Am 21:49-70, viii. 2007
    ..Given the complexity of HIV care in the twenty-first century and the potential for involvement of multiple consultants, the role of primary care provider is perhaps more critical for the HIV-infected patient than for the average patient...
  27. pmc Implementation science of pre-exposure prophylaxis: preparing for public use
    Kristen Underhill
    Department of Community Health, Brown University, Providence, RI 02912, USA
    Curr HIV/AIDS Rep 7:210-9. 2010
    ..The lessons from PrEP planning can benefit the scale-up of future combination interventions...
  28. ncbi request reprint Mapping cross-clade HIV-1 vaccine epitopes using a bioinformatics approach
    Anne S De Groot
    TB HIV Research Lab, Brown University, Providence, RI 02912, USA
    Vaccine 21:4486-504. 2003
    ..Putative HIV-1 CTL epitopes were selected from this list using the epitope prediction tool EpiMatrix...
  29. ncbi request reprint Opportunities for preventing HIV in treatment settings in developing countries
    Mark N Lurie
    Brown University Medical School, Miriam Hospital, Providence, Rhode Island 02912, USA
    Lancet Infect Dis 5:66-8. 2005
  30. ncbi request reprint Engineering immunogenic consensus T helper epitopes for a cross-clade HIV vaccine
    Anne S De Groot
    TB HIV Research Lab, Brown University, Providence RI 02912, USA
    Methods 34:476-87. 2004
    ..These data confirm the utility of bioinformatics tools to select and construct novel "immunogenic consensus sequence" T cell epitopes for a globally relevant vaccine against HIV...
  31. pmc Development of guidelines on nonoccupational HIV postexposure prophylaxis for the state of Rhode Island
    Roland C Merchant
    Division of Infectious Diseases, Section of Emergency Medicine, Brown Medical School, Department of Emergency Medicine, Rhode Island Hospital, Providence, RI, USA
    Public Health Rep 119:136-40. 2004
    ..The guidelines serve as both a resource for health care practitioners and a means of educating them on this method of HIV prevention...
  32. pmc Predictors of the initiation of HIV postexposure prophylaxis in Rhode Island emergency departments
    Roland C Merchant
    Departments of Emergency Medicine and Community Health, Brown Medical School, Providence, Rhode Island 02903, USA
    AIDS Patient Care STDS 22:41-52. 2008
    ..ED providers should ensure that these factors do not inappropriately restrict its initiation...
  33. doi request reprint Acceptability of tenofovir gel as a vaginal microbicide among women in a phase I trial: a mixed-methods study
    Rochelle K Rosen
    The Miriam Hospital, Providence, Rhode Island 02903, USA
    J Womens Health (Larchmt) 17:383-92. 2008
    ..The impact of acceptability factors on use of the gel and the relationship between qualitative and quantitative acceptability data are explored...
  34. pmc Beyond anal sex: sexual practices associated with HIV risk reduction among men who have sex with men in Boston, Massachusetts
    Sari L Reisner
    The Fenway Institute, Fenway Community Health, Boston, Massachusetts 02119, USA
    AIDS Patient Care STDS 23:545-50. 2009
    ..12; p < 0.05) in the previous 12 months. Identifying and understanding such factors associated with risk reduction behaviors may be important to consider in designing effective prevention interventions to promote sexual health for MSM...
  35. ncbi request reprint ART adherence, demographic variables and CD4 outcome among HIV-positive patients on antiretroviral therapy in Chennai, India
    S A Safren
    Harvard Medical School and Massachsetts General Hospital, Boston, MA, USA
    AIDS Care 17:853-62. 2005
    ....
  36. doi request reprint Walking the line: stimulant use during sex and HIV risk behavior among Black urban MSM
    Matthew J Mimiaga
    The Fenway Institute, Fenway Community Health, Boston, MA 02215, United States
    Drug Alcohol Depend 110:30-7. 2010
    ..Although the association of stimulant use to sexual risk taking and HIV transmission has been well documented among white gay men, stimulant use during sex continues to be under-explored among Black men who have sex with men (MSM)...
  37. pmc Emergency department evaluations of non-percutaneous blood or body fluid exposures during cardiopulmonary resuscitation
    Roland C Merchant
    Department of Emergency Medicine, Brown Medical School, Providence, Rhode Island, USA
    Prehosp Disaster Med 22:330-4. 2007
    ....
  38. ncbi request reprint Detection of hepatitis C virus (HCV) in serum and peripheral-blood mononuclear cells from HCV-monoinfected and HIV/HCV-coinfected persons
    Jason T Blackard
    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Infect Dis 192:258-65. 2005
    ..These data suggest differential regulation of HCV RNA in the serum and PBMC compartments and may partially explain the limited HCV antiviral response rates observed in coinfected persons...
  39. pmc Predictors of identifying as a barebacker among high-risk New England HIV seronegative men who have sex with men
    Sari L Reisner
    The Fenway Institute, Fenway Community Health, Boston, MA, USA
    J Urban Health 86:250-62. 2009
    ..Additional research is warranted to understand the social identity of barebacking among MSM in order to develop more nuanced prevention strategies...
  40. pmc Street workers and internet escorts: contextual and psychosocial factors surrounding HIV risk behavior among men who engage in sex work with other men
    Matthew J Mimiaga
    The Fenway Institute, Fenway Community Health, Prudential Tower, 4th Floor, 800 Boylston Street, Boston, MA 02119, USA
    J Urban Health 86:54-66. 2009
    ..Study findings can be used to generate hypotheses for designing and providing tailored primary and secondary prevention interventions for this at-risk subgroup of MSM...
  41. doi request reprint HIV transmission transcends three generations: can we prevent secondary transmission in India?
    Kartik K Venkatesh
    Brown University Medical School, Providence, RI, USA
    Int J STD AIDS 19:418-20. 2008
    ....
  42. doi request reprint Psychosocial and behavioral predictors of partner notification after HIV and STI exposure and infection among MSM
    Matthew J Mimiaga
    The Fenway Institute, Fenway Community Health, Prudential Tower, 4th Floor, 800 Boylston Street, Boston, MA 02119, USA
    AIDS Behav 13:738-45. 2009
    ..Results suggest how to increase acceptability and use of PN as a public health strategy and underscore the need for counseling as part of the notification process...
  43. ncbi request reprint Developing an HIV-prevention intervention for HIV-infected men who have sex with men in HIV care: project enhance
    Robert O Knauz
    Fenway Community Health, 7 Haviland Street, Boston, MA 02115, USA
    AIDS Behav 11:S117-26. 2007
    ..The result of this process is an example of an intervention developed with strong input from the community and other stakeholders, which is ready for further testing in a randomized controlled trial...
  44. ncbi request reprint Changes in total lymphocyte count as a surrogate for changes in CD4 count following initiation of HAART: implications for monitoring in resource-limited settings
    Anish P Mahajan
    School of Medicine, Brown University, Providence, RI, 02906, USA
    J Acquir Immune Defic Syndr 36:567-75. 2004
    ..The total lymphocyte count (TLC) has been proposed as a surrogate marker to monitor immune response to therapy...
  45. pmc Blood or body fluid exposures and HIV postexposure prophylaxis utilization among first responders
    Roland C Merchant
    Department of Emergency Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA
    Prehosp Emerg Care 13:6-13. 2009
    ....
  46. pmc Emergency department patient acceptance of opt-in, universal, rapid HIV screening
    Roland C Merchant
    Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA
    Public Health Rep 123:27-40. 2008
    ..We assessed emergency department (ED) patient acceptance of opt-in, rapid human immunodeficiency virus (HIV) screening and identified demographic characteristics and HIV testing-history factors associated with acceptance of screening...
  47. pmc The relationship of reported HIV risk and history of HIV testing among emergency department patients
    Roland C Merchant
    Department of Emergency Medicine, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA
    Postgrad Med 122:61-74. 2010
    ..Among a random sample of emergency department (ED) patients, we sought to determine the extent to which reported risk for human immunodeficiency virus (HIV) is related to ever having been tested for HIV...
  48. ncbi request reprint Safety and tolerability of vaginal PRO 2000 gel in sexually active HIV-uninfected and abstinent HIV-infected women
    Kenneth H Mayer
    Infectious Disease Division, Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, USA
    AIDS 17:321-9. 2003
    ....
  49. ncbi request reprint Tricks of the trade: sexual health behaviors, the context of HIV risk, and potential prevention intervention strategies for male sex workers
    Sari L Reisner
    The Fenway Institute, Fenway Health, Boston, MA 02215, USA
    J LGBT Health Res 4:195-209. 2008
    ..Multipronged interventions to decrease sexual risk taking among male sex workers would also benefit from addressing the unique socioeconomic and legal needs of this population...
  50. pmc Health system and personal barriers resulting in decreased utilization of HIV and STD testing services among at-risk black men who have sex with men in Massachusetts
    Matthew J Mimiaga
    The Fenway Institute, Fenway Health, Boston, MA 02119, USA
    AIDS Patient Care STDS 23:825-35. 2009
    ..Additional provider training is warranted to educate HCPs about the specific health care needs of Black MSM, in order to facilitate access to timely, culturally competent HIV and STD testing and treatment services for this population...
  51. pmc Functional impairment and health care utilization among HIV-infected men who have sex with men: the relationship with depression and post-traumatic stress
    CONALL O'CLEIRIGH
    Fenway Health, Boston, MA, USA
    J Behav Med 32:466-77. 2009
    ....
  52. doi request reprint Methicillin-resistant Staphylococcus aureus colonization, behavioral risk factors, and skin and soft-tissue infection at an ambulatory clinic serving a large population of HIV-infected men who have sex with men
    John D Szumowski
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Clin Infect Dis 49:118-21. 2009
    ..Of the patients who were colonized with MRSA at study entry, 36.7% developed an SSTI during the ensuing 12 months, compared with 8.1% of persons who were not colonized with MRSA...
  53. pmc Sexual mixing patterns and partner characteristics of black MSM in Massachusetts at increased risk for HIV infection and transmission
    Matthew J Mimiaga
    The Fenway Institute, Fenway Community Health, 1340 Boylston Street, Boston, MA 02215, USA
    J Urban Health 86:602-23. 2009
    ..Effective prevention strategies need to address the distinct sexual and behavioral risk patterns presented by different sexual partnerships reported by Black MSM...
  54. doi request reprint Clinically significant depressive symptoms as a risk factor for HIV infection among black MSM in Massachusetts
    Sari L Reisner
    The Fenway Institute, Fenway Health, 1340 Boylston Street, 8th Floor, Boston, MA 02215, USA
    AIDS Behav 13:798-810. 2009
    ..HIV prevention interventions for Black MSM may benefit from incorporating screening and/or treatment for depression, allowing MSM who are depressed to respond more effectively to behavioral change approaches...
  55. pmc Childhood sexual abuse is highly associated with HIV risk-taking behavior and infection among MSM in the EXPLORE Study
    Matthew J Mimiaga
    Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
    J Acquir Immune Defic Syndr 51:340-8. 2009
    ....
  56. pmc Preexposure antiretroviral prophylaxis attitudes in high-risk Boston area men who report having sex with men: limited knowledge and experience but potential for increased utilization after education
    Matthew J Mimiaga
    The Fenway Institute, Fenway Community Health, Boston, MA 02119, USA
    J Acquir Immune Defic Syndr 50:77-83. 2009
    ..Understanding the demographic and behavioral predictors of intent-to-use PrEP may prove useful to identify clinical trial participants...
  57. pmc A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals
    Steven A Safren
    Fenway Community Health, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Health Psychol 28:1-10. 2009
    ..To evaluate cognitive-behavioral therapy to enhance medication adherence and reduce depression (CBT-AD) in individuals with HIV...
  58. ncbi request reprint Herpes simplex virus type 2 infection as a risk factor for human immunodeficiency virus acquisition in men who have sex with men
    Cristina Renzi
    Department of Medicine, University of Washington, Seattle, USA
    J Infect Dis 187:19-25. 2003
    ..HSV-2 increases the risk of HIV acquisition, independent of recognized herpes lesions and behaviors reflecting potential HIV exposure. HSV-2 suppression with antiviral therapy should be evaluated as an HIV prevention strategy among MSM...
  59. ncbi request reprint Men who have sex with men: perceptions about sexual risk, HIV and sexually transmitted disease testing, and provider communication
    Matthew J Mimiaga
    The Fenway Institute, Fenway Community Health, Boston, Massachusetts 02199, USA
    Sex Transm Dis 34:113-9. 2007
    ..This study was designed to gain a deeper understanding of the barriers and facilitators related to sexually transmitted diseases (STDs) and HIV screening among at-risk Boston men who have sex with men (MSM)...
  60. ncbi request reprint Prevalence of hepatitis C virus infection among men who have sex with men at a Boston community health center and its association with markers of high-risk behavior
    Daniel E Cohen
    Fenway Community Health, Boston, 7 Haviland Street, Massachusetts 02115, USA
    AIDS Patient Care STDS 20:557-64. 2006
    ..HCV prevention and screening should target MSM engaging in high-risk sex. Conversely, HIV and sexually transmitted infection risk reduction interventions should be targeted at MSM with HCV...
  61. pmc Effectiveness of increasing emergency department patients' self-perceived risk for being human immunodeficiency virus (HIV) infected through audio computer self-interview-based feedback about reported HIV risk behaviors
    Roland C Merchant
    Department of Emergency Medicine, Alpert Medical School of Brown University, Providence, RI, USA
    Acad Emerg Med 16:1143-55. 2009
    ..The intervention aimed to increase patient's self-perceived risk of being HIV infected by providing immediate feedback on their risk behaviors...
  62. ncbi request reprint Urine-based asymptomatic urethral gonorrhea and chlamydia screening and sexual risk-taking behavior in men who have sex with men in greater Boston
    Christopher J Russell
    Fenway Community Health, Boston, Massachusetts, Current affiliation Harvard Medical School, Boston, Massachusetts 02115, USA
    AIDS Patient Care STDS 21:205-11. 2007
    ..Increased awareness of STD symptoms among patients and medical providers is critical to timely diagnosis and treatment of STDs in MSM...
  63. ncbi request reprint Dichotomy in cross-clade reactivity and neutralization by HIV-1 sera: Implications for active and passive immunotherapy
    Lisa A Cavacini
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Med Virol 76:146-52. 2005
    ..Understanding antibody responses to native virions after Clade C infection and cross clade antibody behavior has implications for understanding pathogenesis and vaccine development...
  64. ncbi request reprint MSM in HIV-prevention trials are sexual partners with each other: An ancillary study to the EXPLORE intervention
    Matthew J Mimiaga
    Department of Research and Evaluation, Fenway Community Health, Boston, Massachusetts 02115, USA
    AIDS Behav 10:27-34. 2006
    ..Future HIV-prevention studies recruiting MSM at increased sexual risk of HIV infection should address participants potentially becoming sexual partners with each other...
  65. ncbi request reprint Lessons learned from use of highly active antiretroviral therapy in Africa
    Chitra Akileswaran
    Brown University Medical School, Providence, RI 02912, USA
    Clin Infect Dis 41:376-85. 2005
    ..Moreover, clinical and laboratory outcomes were compiled to determine the effectiveness of HAART programs...
  66. ncbi request reprint Association between paired plasma and cervicovaginal lavage fluid HIV-1 RNA levels during 36 months
    Susan Cu-Uvin
    The Miriam Hospital, Brown Medical School, Providence, Rhode Island, USA
    J Acquir Immune Defic Syndr 42:584-7. 2006
    ..To determine the patterns and predictors of genital tract HIV-1 RNA levels during a 36-month period...
  67. doi request reprint Sources of human immunodeficiency virus and sexually transmitted disease information and responses to prevention messages among Massachusetts men who have sex with men
    Matthew J Mimiaga
    The Fenway Institute, Fenway Community Health, Boston, MA 02199, USA
    Am J Health Promot 24:170-7. 2010
    ..This was done to understand how to design more effective media campaigns on HIV/STD prevention and testing for this population...
  68. doi request reprint Experiences and sexual behaviors of HIV-infected MSM who acquired HIV in the context of crystal methamphetamine use
    Matthew J Mimiaga
    Fenway Institute, Fenway Community Health, Boston, MA 02119, USA
    AIDS Educ Prev 20:30-41. 2008
    ..The study also draws attention to the need for associated mental health, functional and quality-of life impairments that seem to accompany continued use in individuals with HIV...
  69. ncbi request reprint Perspectives on new recommendations for nonoccupational HIV postexposure prophylaxis
    Roland C Merchant
    Department of Emergency Medicine, Brown Medical School, Providence, RI, USA
    JAMA 293:2407-9. 2005
  70. pmc Treatment and outcomes of infections by methicillin-resistant Staphylococcus aureus at an ambulatory clinic
    John D Szumowski
    Harvard Medical School, and The Fenway Institute c o Daniel Cohen, Fenway Community Health, 7 Haviland Street, Boston, MA 02115, USA
    Antimicrob Agents Chemother 51:423-8. 2007
    ..TMP-SMX appears to be an appropriate empirical antibiotic for suspected MRSA SSTI, especially where clindamycin resistance is common...
  71. pmc Health care access and sexually transmitted infection screening frequency among at-risk Massachusetts men who have sex with men
    Carey V Johnson
    The Fenway Institute, Fenway Community Health, 7 Haviland St, Boston, MA 02115 2683, USA
    Am J Public Health 99:S187-92. 2009
    ..We sought to assess risk exposures, health care access, and screening rates for HIV and sexually transmitted infections (STIs) among men who have sex with men (MSM) in Massachusetts...
  72. doi request reprint Anal human papillomavirus infection is associated with HIV acquisition in men who have sex with men
    Peter V Chin-Hong
    Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    AIDS 23:1135-42. 2009
    ..Our aim was to determine the association between anal HPV infection and HIV acquisition...
  73. ncbi request reprint The changing natural history of HIV disease: before and after the introduction of generic antiretroviral therapy in southern India
    N Kumarasamy
    YRG Centre for AIDS Research and Education, Voluntary Health Services, Chennai, India
    Clin Infect Dis 41:1525-8. 2005
    ..The incidence of tuberculosis and opportunistic infections decreased to <2 cases per 100 person-years. Death rates decreased from 25 to 5 deaths per 100 person-years between 1997 and 2003...
  74. ncbi request reprint Estimating causal treatment effects from longitudinal HIV natural history studies using marginal structural models
    Hyejin Ko
    Samsung SDS, Ltd, 707 19, Yoksam Dong, Kangnam Gu, Seoul 135 918, South Korea
    Biometrics 59:152-62. 2003
    ..The findings from our analysis are consistent with recent treatment guidelines set by the U.S. Panel of the International AIDS Society (Carpenter et al., 2000, Journal of the American Medical Association 280, 381-391)...
  75. ncbi request reprint Clinical profile of HIV in India
    N Kumarasamy
    Y R G Center for AIDS Research and Education CARE, Voluntary Health Services, Tharamani, Chennai 600 113, India
    Indian J Med Res 121:377-94. 2005
    ..With the availability of antiretroviral therapy at lower cost, the clinical profile of HIV disease in India is now changing to include drug-related toxicities and immune reconstitution syndrome...
  76. ncbi request reprint Low-cost monitoring of HIV infected individuals on highly active antiretroviral therapy (HAART) in developing countries
    Pachamuthu Balakrishnan
    YRG Centre for AIDS Research and Education, Voluntary Health Services Campus, Taramani, Chennai 600 113, India
    Indian J Med Res 121:345-55. 2005
    ..This review discusses the low-cost assays and their role in clinical monitoring of HIV infected individuals in resource-limited countries like as India...
  77. ncbi request reprint Barriers and facilitators to antiretroviral medication adherence among patients with HIV in Chennai, India: a qualitative study
    N Kumarasamy
    YRG CARE, Chennai, India
    AIDS Patient Care STDS 19:526-37. 2005
    ..These data highlight the importance of reducing the cost of antiretroviral medications, involving family members in HIV care, and addressing privacy issues and stigma in counseling interventions in this setting...
  78. ncbi request reprint An approach to addressing ethical issues in a community-based risk assessment for HIV: a case from Chennai, India
    Sudha Sivaram
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    J Health Popul Nutr 23:165-76. 2005
    ..This framework discusses the role of community participation, transparent and comprehensive informed consent, timely dissemination of results, and access to follow-up care for those living with HIV/STDs...
  79. ncbi request reprint Safe discontinuation of primary pneumocystis prophylaxis in Southern Indian HIV-infected patients on highly active antiretroviral therapy
    N Kumarasamy
    J Acquir Immune Defic Syndr 40:377-8. 2005
  80. ncbi request reprint HIV type 1 genotypic variation in an antiretroviral treatment-naive population in southern India
    Pachamuthu Balakrishnan
    YRG CARE, Centre for AIDS Research and Education, VHS, Taramani, Chennai 600 113, India
    AIDS Res Hum Retroviruses 21:301-5. 2005
    ..Larger scale studies need to be undertaken to better define the genotypic variation of circulating Indian subtype C viruses and their potential impact on drug susceptibility and clinical outcome in treated individuals...
  81. ncbi request reprint Adverse effects of highly active antiretroviral therapy in developing countries
    Ramnath Subbaraman
    Yale School of Medicine, New Haven, Connecticut, USA
    Clin Infect Dis 45:1093-101. 2007
    ....
  82. ncbi request reprint Total lymphocyte count (TLC) is a useful tool for the timing of opportunistic infection prophylaxis in India and other resource-constrained countries
    N Kumarasamy
    Y R G Centre for AIDS Research and Education, Chennai, India
    J Acquir Immune Defic Syndr 31:378-83. 2002
    ..To determine a range of TLC cutoffs for the initiation of OI prophylaxis that is appropriate for resource-constrained settings...
  83. ncbi request reprint Monitoring HIV treatment in the developing world
    N Kumarasamy
    YRG Centre for AIDS Research and Education, Chennai, India
    Lancet Infect Dis 2:656-7. 2002
  84. ncbi request reprint Dried blood spots (DBS): a valuable tool for HIV surveillance in developing/tropical countries
    Sunil S Solomon
    Shri Ramachandra Medical College, Porur, Chennai, India
    Int J STD AIDS 13:25-8. 2002
    ..Based on these findings, we conclude that DBS sampling could serve as a cost-effective and convenient tool for widespread HIV sero-surveillance in remote areas within tropical countries...
  85. ncbi request reprint Use of highly active antiretroviral therapy in HIV-infected women: impact of HIV specialist care
    Lytt I Gardner
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Acquir Immune Defic Syndr 29:69-75. 2002
    ..To evaluate factors associated with use of HIV specialist care by women, and to determine whether medical indications for therapy validate lower rates of antiretroviral use in women not using HIV specialty care...
  86. ncbi request reprint Prevalence and cumulative incidence of and risk factors for anemia in a multicenter cohort study of human immunodeficiency virus-infected and -uninfected women
    Richard D Semba
    Department of Ophthalmology, Schools of Medicine and Hygiene and of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Clin Infect Dis 34:260-6. 2002
    ..94), history of fever (OR, 1.42; 95% CI, 1.13-1.80), and zidovudine use (OR, 1.14; 95% CI, 1.01-1.30). Anemia was common and associated with an increased risk of death (hazards ratio, 1.64; 95% CI, 1.21-2.23) among HIV-positive women...
  87. ncbi request reprint Bacterial vaginosis in female sex workers in Chennai, India
    Shanmugasundaram Uma
    Sex Health 2:261-2. 2005
    ..3, AR 12, P = 0.00), T vaginalis (RR 1.5, AR 10, P = 0.01) T. pallidum (RR 2.8, AR 16, P = 0.00) and HIV (RR 4.1, AR 52, P = 0.01). Future studies are needed to focus on the risk factors for BV...
  88. ncbi request reprint Breakthrough infections during phase 1 and 2 prime-boost HIV-1 vaccine trials with canarypox vectors (ALVAC) and booster dose of recombinant gp120 or gp160
    Deborah Lee
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    J Infect Dis 190:903-7. 2004
    ..4, P =.1, and P =.7, respectively). Persons who acquire HIV-1 infection while enrolled in HIV-1 vaccine trials can be successfully followed after infection, to determine whether vaccines alter the course of HIV-1 infection...
  89. ncbi request reprint Sexual behaviors of individuals with HIV living in South India: a qualitative study
    A K Sri Krishnan
    YRG CARE, Chennai, India
    AIDS Educ Prev 19:334-45. 2007
    ....
  90. ncbi request reprint Safety of switching to nevirapine-based highly active antiretroviral therapy at elevated CD4 cell counts in a resource-constrained setting
    N Kumarasamy
    J Acquir Immune Defic Syndr 45:598-600. 2007
  91. ncbi request reprint An inexpensive, simple, and manual method of CD4 T-cell quantitation in HIV-infected individuals for use in developing countries
    Pachamuthu Balakrishnan
    YRG Centre for AIDS Research and Education, Voluntary Health Services, Taramani, Chennai, India
    J Acquir Immune Defic Syndr 36:1006-10. 2004
    ..Hence, the cytosphere assay can be an alternate to flow cytometry for the estimation of CD4+ T-lymphocyte counts, especially in resource-poor settings of developing countries, for monitoring HIV progression and response to therapy...
  92. ncbi request reprint Reasons for modification of generic highly active antiretroviral therapeutic regimens among patients in southern India
    Nagalingeswaran Kumarasamy
    YRG Centre for AIDS Research and Education, Chennai, India
    J Acquir Immune Defic Syndr 41:53-8. 2006
    ..To describe reasons for modification and discontinuation of antiretroviral regimens in association with adverse events (AEs), treatment failure, and cost among patients in southern India...
  93. ncbi request reprint Bacterial vaginosis in women of low socioeconomic status living in slum areas in Chennai, India
    Shanmugasundaram Uma
    Sex Health 3:297-8. 2006
    ..vaginalis (relative risk (RR) = 6.6, 95% CI 2.8-15.5, P = 0.000) and HSV-2 (RR = 2, 95% CI 1.3-2.9; P = 0.0031). The role of other possible risk factors needs to be explored...
  94. ncbi request reprint Incidence of immune reconstitution syndrome in HIV/tuberculosis-coinfected patients after initiation of generic antiretroviral therapy in India
    N Kumarasamy
    YRG Center for Research and Education, VHS, Tharamani, Chennai, India
    J Acquir Immune Defic Syndr 37:1574-6. 2004
    ....
  95. doi request reprint Immunological rebound after initiation of highly active antiretroviral therapy in treatment-naive patients
    Jason T Blackard
    Division of Digestive Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    AIDS Res Hum Retroviruses 24:499-504. 2008
    ..Future studies of immunological rebound are warranted to further define and characterize immune responses to HAART in diverse populations in order to optimize guidelines for initiation of treatment and assessment of successful responses...
  96. doi request reprint Spectrum of adverse events after generic HAART in southern Indian HIV-infected patients
    N Kumarasamy
    YRG Centre for AIDS Research and Education, VHS, Chennai, India
    AIDS Patient Care STDS 22:337-44. 2008
    ..05). Anemia and hepatitis often occur within 12 weeks of initiating generic HAART. Frequent and early monitoring for these toxicities is warranted in developing countries where generic HAART is increasingly available...
  97. ncbi request reprint The safety, tolerability and effectiveness of generic antiretroviral drug regimens for HIV-infected patients in south India
    Nagalingeswaran Kumarasamy
    YRG Centre for AIDS Research and Education, Chennai, India
    AIDS 17:2267-9. 2003
    ..In this cohort, generic HAART was safe, well tolerated and effective at increasing CD4 T-lymphocyte counts in patients with advanced HIV, comparable to the experience with proprietary HAART...
  98. ncbi request reprint Mucosal innate immune factors in secretions from high-risk individuals immunized with a bivalent gp120 vaccine
    James E Cummins
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    AIDS Res Hum Retroviruses 23:748-54. 2007
    ..Because of the importance of innate immunity in host defense, evaluation of the mucosal innate immune system should be included in future HIV prevention trials...
  99. ncbi request reprint Risk reduction counseling is associated with decreased HIV transmission-associated behaviors in high-risk Indian heterosexuals
    Sunil S Solomon
    YR Gaitonde Center for AIDS Research and Education YRG CARE, Chennai, India
    J Acquir Immune Defic Syndr 42:478-83. 2006
    ..To estimate the incidence of HIV and study the impact of risk-reduction counseling (RRC) in a cohort of people with high-risk behavior for HIV transmission in Chennai, India...
  100. ncbi request reprint Case studies on nonoccupational postexposure HIV prophylaxis
    Brenda Y Urbina
    Med Health R I 86:175-7. 2003
  101. ncbi request reprint Demographic and clinical characteristics of HIV-infected inpatients and outpatients at a Cambodian hospital
    Phan Sok
    Sihanouk Hospital Center of HOPE, Phnom Penh, Cambodia
    AIDS Patient Care STDS 20:369-78. 2006
    ..HIV physicians in Cambodia should be aware of the likelihood for multiple OIs or conditions when patients present weight loss more than 10% from baseline...

Research Grants9

  1. Enhancing HIV Prevention Among High-Risk HIV+ Men
    Kenneth Mayer; Fiscal Year: 2007
    ..Participants will then be followed every three months for one year, integrating PCM and/or prevention booster sessions to their HIV care visits. ..
  2. HIV PREVENTION TRIAL UNITS
    Kenneth Mayer; Fiscal Year: 2007
    ..We will continue our leadership work in community education and the engagement of diverse communities in HIV prevention initiatives. ( ..