Devin C Koestler

Summary

Affiliation: Brown University
Country: USA

Publications

  1. pmc Semi-supervised recursively partitioned mixture models for identifying cancer subtypes
    Devin C Koestler
    Department of Community Health, Section for Biostatistics, Center for Environmental Health and Technology, Brown University, Providence, RI 02912, USA
    Bioinformatics 26:2578-85. 2010
  2. pmc In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta
    Charlotte S Wilhelm-Benartzi
    Department of Epidemiology, Center for Environmental Health and Technology, Brown University, Providence, Rhode Island, USA
    Environ Health Perspect 120:296-302. 2012
  3. pmc DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer
    Carmen J Marsit
    Pathology and Laboratory Medicine, Brown University, Providence, RI 02912, USA
    J Clin Oncol 29:1133-9. 2011
  4. pmc Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers
    Devin C Koestler
    Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA
    Cancer Epidemiol Biomarkers Prev 21:1293-302. 2012
  5. pmc Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome-wide association study
    Scott M Langevin
    Department of Epidemiology, Brown University, Providence, RI, USA
    Epigenetics 7:291-9. 2012
  6. pmc Downregulated microRNAs in the differential diagnosis of malignant pleural mesothelioma
    Gretchen V Gee
    Department of Pathology and Laboratory Medicine, Brown University, Providence, RI 02912, USA
    Int J Cancer 127:2859-69. 2010
  7. pmc Association of secondhand smoke exposures with DNA methylation in bladder carcinomas
    Charlotte S Wilhelm-Benartzi
    Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA
    Cancer Causes Control 22:1205-13. 2011
  8. pmc Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma
    Michele Avissar-Whiting
    Department of Pathology, Brown University, Providence, RI, USA
    Epigenetics 6:703-9. 2011
  9. pmc Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas
    Carolyn E Banister
    Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA
    Epigenetics 6:920-7. 2011
  10. pmc DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma
    Brock C Christensen
    Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA
    J Natl Cancer Inst 103:143-53. 2011

Collaborators

Detail Information

Publications11

  1. pmc Semi-supervised recursively partitioned mixture models for identifying cancer subtypes
    Devin C Koestler
    Department of Community Health, Section for Biostatistics, Center for Environmental Health and Technology, Brown University, Providence, RI 02912, USA
    Bioinformatics 26:2578-85. 2010
    ..We propose a method called semi-supervised recursively partitioned mixture models (SS-RPMM) that utilizes array-based genetic and patient-level clinical data for finding cancer subtypes that are associated with patient survival...
  2. pmc In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta
    Charlotte S Wilhelm-Benartzi
    Department of Epidemiology, Center for Environmental Health and Technology, Brown University, Providence, Rhode Island, USA
    Environ Health Perspect 120:296-302. 2012
    ..Environmental insults in utero may lead to changes in epigenetic mechanisms potentially affecting fetal development...
  3. pmc DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer
    Carmen J Marsit
    Pathology and Laboratory Medicine, Brown University, Providence, RI 02912, USA
    J Clin Oncol 29:1133-9. 2011
    ..We sought to identify specific profiles of DNA methylation in peripheral blood that are associated with bladder cancer risk and therefore serve as an epigenetic marker of disease susceptibility...
  4. pmc Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers
    Devin C Koestler
    Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA
    Cancer Epidemiol Biomarkers Prev 21:1293-302. 2012
    ....
  5. pmc Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome-wide association study
    Scott M Langevin
    Department of Epidemiology, Brown University, Providence, RI, USA
    Epigenetics 7:291-9. 2012
    ..This profile demonstrates the potential of DNA methylation measured in blood for development of non-invasive applications for detection of head and neck cancer...
  6. pmc Downregulated microRNAs in the differential diagnosis of malignant pleural mesothelioma
    Gretchen V Gee
    Department of Pathology and Laboratory Medicine, Brown University, Providence, RI 02912, USA
    Int J Cancer 127:2859-69. 2010
    ..This research points to novel approaches using miRNAs whose decreased expression is unique to mesothelioma as potentially suitable for rapid diagnosis and reveals prospective new targets for the treatment of this deadly disease...
  7. pmc Association of secondhand smoke exposures with DNA methylation in bladder carcinomas
    Charlotte S Wilhelm-Benartzi
    Department of Community Health Center for Environmental Health and Technology, Brown University, Providence, RI, USA
    Cancer Causes Control 22:1205-13. 2011
    ..Epigenetic alterations in bladder tumors have been linked to primary cigarette smoking and could add to the biological plausibility of an association between SHS exposure and bladder cancer...
  8. pmc Polycomb group genes are targets of aberrant DNA methylation in renal cell carcinoma
    Michele Avissar-Whiting
    Department of Pathology, Brown University, Providence, RI, USA
    Epigenetics 6:703-9. 2011
    ..This work contributes to our understanding of how repressive marks on DNA and chromatin are dysregulated in carcinogenesis, knowledge that might aid the development of therapies or preventive strategies for human malignancies...
  9. pmc Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas
    Carolyn E Banister
    Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA
    Epigenetics 6:920-7. 2011
    ....
  10. pmc DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma
    Brock C Christensen
    Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA
    J Natl Cancer Inst 103:143-53. 2011
    ....
  11. pmc Placental DNA methylation alterations associated with maternal tobacco smoking at the RUNX3 gene are also associated with gestational age
    Jennifer Z J Maccani
    Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA
    Epigenomics 5:619-30. 2013
    ..The aim of this study was to investigate the relationship between maternal smoking during pregnancy, methylation changes in the placenta and gestational age...