Valerie Knopik

Summary

Affiliation: Brown University
Country: USA

Publications

  1. ncbi The epigenetics of maternal cigarette smoking during pregnancy and effects on child development
    Valerie S Knopik
    Rhode Island Hospital, RI, USA
    Dev Psychopathol 24:1377-90. 2012
  2. ncbi Genetic and environmental influences on externalizing behavior and alcohol problems in adolescence: a female twin study
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Box G S121 4, Providence, RI 02912, United States
    Pharmacol Biochem Behav 93:313-21. 2009
  3. ncbi Paternal alcoholism and offspring ADHD problems: a children of twins design
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Warren Alpert Medical School of Brown University, Providence, RI 02912, United States of America
    Twin Res Hum Genet 12:53-62. 2009
  4. ncbi Maternal smoking during pregnancy and child outcomes: real or spurious effect?
    Valerie S Knopik
    Department of Community Health, Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island 02912, USA
    Dev Neuropsychol 34:1-36. 2009
  5. ncbi Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk: a female twin study
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
    Psychol Med 35:625-35. 2005
  6. ncbi Maternal alcohol use disorder and offspring ADHD: disentangling genetic and environmental effects using a children-of-twins design
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
    Psychol Med 36:1461-71. 2006
  7. ncbi Examining the heritability of a laboratory-based smoking endophenotype: initial results from an experimental twin study
    Lara A Ray
    Department of Psychology and Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, United States of America
    Twin Res Hum Genet 10:546-53. 2007
  8. ncbi Initial evidence of an association between OPRM1 and adolescent alcohol misuse
    Robert Miranda
    Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA
    Alcohol Clin Exp Res 34:112-22. 2010
  9. ncbi Associations of the DRD2 TaqIA polymorphism with impulsivity and substance use: preliminary results from a clinical sample of adolescents
    Christianne Esposito-Smythers
    Center for Alcohol and Addiction Studies, Brown University, United States
    Pharmacol Biochem Behav 93:306-12. 2009
  10. ncbi Limitations of DSM-IV operationalizations of alcohol abuse and dependence in a sample of Australian twins
    Michael T Lynskey
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Twin Res Hum Genet 8:574-84. 2005

Research Grants

  1. Externalizing Behavior: Genetics x Prenatal Nicotine
    Valerie Knopik; Fiscal Year: 2007
  2. Prenatal tobacco exposure: effects on neuropsychological outcomes and ADHD
    Valerie Knopik; Fiscal Year: 2009

Detail Information

Publications15

  1. ncbi The epigenetics of maternal cigarette smoking during pregnancy and effects on child development
    Valerie S Knopik
    Rhode Island Hospital, RI, USA
    Dev Psychopathol 24:1377-90. 2012
    ..We also outline future directions for this new and exciting field of research...
  2. ncbi Genetic and environmental influences on externalizing behavior and alcohol problems in adolescence: a female twin study
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Box G S121 4, Providence, RI 02912, United States
    Pharmacol Biochem Behav 93:313-21. 2009
    ..g., comorbid HYP/IMP and CDP vs. comorbid CDP and AlcProb), a finding that could inform different approaches to treatment and prevention...
  3. ncbi Paternal alcoholism and offspring ADHD problems: a children of twins design
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Warren Alpert Medical School of Brown University, Providence, RI 02912, United States of America
    Twin Res Hum Genet 12:53-62. 2009
    ..We present here a complementary analysis using a Children-of-Male-Twin design examining the association between paternal alcoholism and offspring attention deficit hyperactivity problems (ADHP)...
  4. ncbi Maternal smoking during pregnancy and child outcomes: real or spurious effect?
    Valerie S Knopik
    Department of Community Health, Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island 02912, USA
    Dev Neuropsychol 34:1-36. 2009
    ..Carefully designed studies using genetically sensitive strategies can build on current evidence and begin to elucidate the likely complex factors contributing to associations between MSDP and child outcomes...
  5. ncbi Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk: a female twin study
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
    Psychol Med 35:625-35. 2005
    ..Little attention, however, has been directed to investigating the roles of genetic transmission and prenatal exposure simultaneously...
  6. ncbi Maternal alcohol use disorder and offspring ADHD: disentangling genetic and environmental effects using a children-of-twins design
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
    Psychol Med 36:1461-71. 2006
    ....
  7. ncbi Examining the heritability of a laboratory-based smoking endophenotype: initial results from an experimental twin study
    Lara A Ray
    Department of Psychology and Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, United States of America
    Twin Res Hum Genet 10:546-53. 2007
    ..To the best of our knowledge, this is the first study to examine the genetic basis of a laboratory smoking endophenotype, in this case tension reduction after smoking. Implications for genetic association studies are discussed...
  8. ncbi Initial evidence of an association between OPRM1 and adolescent alcohol misuse
    Robert Miranda
    Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA
    Alcohol Clin Exp Res 34:112-22. 2010
    ....
  9. ncbi Associations of the DRD2 TaqIA polymorphism with impulsivity and substance use: preliminary results from a clinical sample of adolescents
    Christianne Esposito-Smythers
    Center for Alcohol and Addiction Studies, Brown University, United States
    Pharmacol Biochem Behav 93:306-12. 2009
    ..It is also possible that DRD2 is related to a behavioral phenotype common to externalizing disorders and substance use...
  10. ncbi Limitations of DSM-IV operationalizations of alcohol abuse and dependence in a sample of Australian twins
    Michael T Lynskey
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Twin Res Hum Genet 8:574-84. 2005
    ....
  11. ncbi Correlates of cigarette smoking during pregnancy and its genetic and environmental overlap with nicotine dependence
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Nicotine Tob Res 10:567-78. 2008
    ....
  12. ncbi Genetic effects on alcohol dependence risk: re-evaluating the importance of psychiatric and other heritable risk factors
    Valerie S Knopik
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Psychol Med 34:1519-30. 2004
    ..Genetic influences have been shown to play a major role in determining the risk of alcohol dependence (AD) in both women and men; however, little attention has been directed to identifying the major sources of genetic variation in AD risk...
  13. ncbi The genetics of middle-age spread in middle-class males
    James C Romeis
    Health Services Research, Department of Health Management and Policy, School of Public Health, Saint Louis University, St Louis, Missouri 63104, USA
    Twin Res 7:596-602. 2004
    ..The data analysis suggests that treatments and public health interventions need to recognize the magnitude of genetic factors if short-term and long-term interventions are to be effective...
  14. ncbi Accuracy of mothers' retrospective reports of smoking during pregnancy: comparison with twin sister informant ratings
    Andrew C Heath
    Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Twin Res 6:297-301. 2003
    ..We conclude that retrospective smoking data can safely be used to identify potential associations of later child outcomes with maternal smoking during pregnancy...
  15. ncbi Quantitative trait locus for reading disability on chromosome 6p is pleiotropic for attention-deficit/hyperactivity disorder
    Erik G Willcutt
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
    Am J Med Genet 114:260-8. 2002
    ....

Research Grants4

  1. Externalizing Behavior: Genetics x Prenatal Nicotine
    Valerie Knopik; Fiscal Year: 2007
    Dr. Valerie Knopik, a behavior geneticist with expertise in quantitative genetics, holds a faculty position in the Department of Psychiatry at Washington University School of Medicine...
  2. Prenatal tobacco exposure: effects on neuropsychological outcomes and ADHD
    Valerie Knopik; Fiscal Year: 2009
    ....