GEORGE KENNA

Summary

Affiliation: Brown University
Country: USA

Publications

  1. ncbi Substance use by pharmacy and nursing practitioners and students in a northeastern state
    George A Kenna
    Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI, USA
    Am J Health Syst Pharm 61:921-30. 2004
  2. pmc Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy
    George A Kenna
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Providence
    Pharmgenomics Pers Med 5:19-35. 2012
  3. pmc The relationship of appetitive, reproductive and posterior pituitary hormones to alcoholism and craving in humans
    George A Kenna
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02912, USA
    Neuropsychol Rev 22:211-28. 2012
  4. ncbi Medications acting on the serotonergic system for the treatment of alcohol dependent patients
    George A Kenna
    Box G S121 5, Brown University, Providence, RI 02912 Roger Williams Hospital USA
    Curr Pharm Des 16:2126-35. 2010
  5. ncbi Review of topiramate: an antiepileptic for the treatment of alcohol dependence
    George A Kenna
    Department of Psychiatry and Human Behavior, Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02908, USA
    Curr Drug Abuse Rev 2:135-42. 2009
  6. doi A safety and tolerability laboratory study of the combination of aripiprazole and topiramate in volunteers who drink alcohol
    George A Kenna
    Department of Psychiatry and the Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA
    Hum Psychopharmacol 24:465-72. 2009
  7. doi A within-group design of nontreatment seeking 5-HTTLPR genotyped alcohol-dependent subjects receiving ondansetron and sertraline
    George A Kenna
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02908, USA
    Alcohol Clin Exp Res 33:315-23. 2009
  8. pmc Risk factors for alcohol and other drug use by healthcare professionals
    George A Kenna
    Center for Alcohol and Addiction Studies, Brown University, Box G 121S 4, Providence, RI 02908, USA
    Subst Abuse Treat Prev Policy 3:3. 2008
  9. ncbi Prevalence of substance use by pharmacists and other health professionals
    George A Kenna
    Department of Community Health, Brown University, Providence, RI 02908, USA
    J Am Pharm Assoc (2003) 44:684-93. 2004
  10. ncbi Pharmacotherapy of dual substance abuse and dependence
    George A Kenna
    Department of Community Health, Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA
    CNS Drugs 21:213-37. 2007

Detail Information

Publications24

  1. ncbi Substance use by pharmacy and nursing practitioners and students in a northeastern state
    George A Kenna
    Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI, USA
    Am J Health Syst Pharm 61:921-30. 2004
    ..The prevalence and predictors of substance use among pharmacists and nurses and pharmacy and nursing students were studied...
  2. pmc Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy
    George A Kenna
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Providence
    Pharmgenomics Pers Med 5:19-35. 2012
    ..Studies assessing 5-HTTLPR as the solitary genetic factor contributing to the etiology of psychiatric disorders continue to face the challenges of statistically small effect sizes and limited replication...
  3. pmc The relationship of appetitive, reproductive and posterior pituitary hormones to alcoholism and craving in humans
    George A Kenna
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02912, USA
    Neuropsychol Rev 22:211-28. 2012
    ..Pharmacotherapies that take advantage of our new understanding of hormones, their receptors, or their potential relationship to craving may shed light on the treatment of this disorder...
  4. ncbi Medications acting on the serotonergic system for the treatment of alcohol dependent patients
    George A Kenna
    Box G S121 5, Brown University, Providence, RI 02912 Roger Williams Hospital USA
    Curr Pharm Des 16:2126-35. 2010
    ..Of course, future studies need to further delineate and confirm the differences between these alcoholic subtypes...
  5. ncbi Review of topiramate: an antiepileptic for the treatment of alcohol dependence
    George A Kenna
    Department of Psychiatry and Human Behavior, Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02908, USA
    Curr Drug Abuse Rev 2:135-42. 2009
    ..While the manufacturer will not pursue approval of an indication for the treatment of alcohol dependence, the drug will soon be available generically, making it more affordable for a greater proportion of the public...
  6. doi A safety and tolerability laboratory study of the combination of aripiprazole and topiramate in volunteers who drink alcohol
    George A Kenna
    Department of Psychiatry and the Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA
    Hum Psychopharmacol 24:465-72. 2009
    ..The ultimate aim for this research is to determine whether this combination is safe and is superior to either drug taken alone in reducing alcohol use in alcohol dependent patients...
  7. doi A within-group design of nontreatment seeking 5-HTTLPR genotyped alcohol-dependent subjects receiving ondansetron and sertraline
    George A Kenna
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02908, USA
    Alcohol Clin Exp Res 33:315-23. 2009
    ..The aim of this study was to match and mismatch L/L, S/S, or S/L genotypes with administration of ondansetron and sertraline...
  8. pmc Risk factors for alcohol and other drug use by healthcare professionals
    George A Kenna
    Center for Alcohol and Addiction Studies, Brown University, Box G 121S 4, Providence, RI 02908, USA
    Subst Abuse Treat Prev Policy 3:3. 2008
    ..Few studies have ever reported predictors or risk factors for alcohol and other drug use (AOD) across a sample of HPs...
  9. ncbi Prevalence of substance use by pharmacists and other health professionals
    George A Kenna
    Department of Community Health, Brown University, Providence, RI 02908, USA
    J Am Pharm Assoc (2003) 44:684-93. 2004
    ....
  10. ncbi Pharmacotherapy of dual substance abuse and dependence
    George A Kenna
    Department of Community Health, Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA
    CNS Drugs 21:213-37. 2007
    ..While ondansetron and olanzapine show some efficacy in treating alcohol and cocaine dependence, more research is needed to better delineate the subpopulation in which these drugs may provide their maximum effect...
  11. ncbi Alcohol use by healthcare professionals
    George A Kenna
    Department of Psychiatry and Human Behavior, Brown University, Butler Hospital, Box G BH, Providence, RI 02912, USA
    Drug Alcohol Depend 75:107-16. 2004
    ..This study investigated alcohol use, misuse and abuse in a sample of dentists, nurses, pharmacists and physicians. Previous studies have lacked cross healthcare group comparisons and have rarely included dentists...
  12. ncbi Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, part 1
    George A Kenna
    Center for Alcohol and Addiction Studies, Brown University, Providence, RI, USA
    Am J Health Syst Pharm 61:2272-9. 2004
    ..The neurobiological basis of alcohol dependence, established pharmacotherapies for alcohol dependence, pharmacotherapies under investigation, and obstacles to treatment are discussed...
  13. ncbi The prevalence of alcohol, cigarette and illicit drug use and problems among dentists
    George A Kenna
    Community Health, Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02908, USA
    J Am Dent Assoc 136:1023-32. 2005
    ..The authors conducted a study to assess self-reported substance use by dentists and compare these data with those regarding physicians and the general population (GP)...
  14. ncbi Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, Part 2
    George A Kenna
    Center for Alcohol and Addiction Studies, Brown University, Providence, RI, USA
    Am J Health Syst Pharm 61:2380-8. 2004
    ..The neurobiological basis of alcohol dependence, established pharmacotherapies for alcohol dependence, pharmacotherapies under investigation, and obstacles to treatment are discussed...
  15. ncbi Can the short index of problems (SIP) be improved? Validity and reliability of the three-month SIP in an emergency department sample
    George A Kenna
    Center for Alcohol and Addiction Studies, Brown University, Box G BH, Providence, Rhode Island 02908, USA
    J Stud Alcohol 66:433-7. 2005
    ....
  16. doi HIV testing in hazardous drinking: a survey analysis
    Miriam Fenton
    Department of Community Health, Brown University Medical School, Providence, Rhode Island 02912, USA
    Subst Use Misuse 45:204-12. 2010
    ..89) the odds of ever having had an HIV test compared to nonhazardous drinkers. Therefore public health interventions targeted at hazardous drinkers to increase the rate of HIV testing are suggested. The study's limitations are noted...
  17. ncbi Turning the clock ahead: potential preclinical and clinical neuropharmacological targets for alcohol dependence
    Lorenzo Leggio
    Center for Alcohol and Addiction Studies, Brown University Medical School, Providence, RI 02912, USA
    Curr Pharm Des 16:2159-18. 2010
    ....
  18. ncbi New developments for the pharmacological treatment of alcohol withdrawal syndrome. A focus on non-benzodiazepine GABAergic medications
    Lorenzo Leggio
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI 02912, USA
    Prog Neuropsychopharmacol Biol Psychiatry 32:1106-17. 2008
    ..The promising results in terms of both safety and efficacy are reported. However, we also note the need of more methodologically controlled studies on a greater number of patients, involving more complicated forms of AWS...
  19. pmc Blood glucose level, alcohol heavy drinking, and alcohol craving during treatment for alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) Study
    Lorenzo Leggio
    Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02912, USA
    Alcohol Clin Exp Res 33:1539-44. 2009
    ..Heavy drinking may increase blood glucose levels. Moreover, in alcohol-dependent subjects, glucose may play a putative role in alcohol preference...
  20. doi Typologies of alcohol dependence. From Jellinek to genetics and beyond
    Lorenzo Leggio
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Box G S 121 4, Providence, RI 02912, USA
    Neuropsychol Rev 19:115-29. 2009
    ..Greater emphasis, however, must be made to more clearly delineate this field of research, while moving toward more standardized typologies...
  21. doi Relationship between the hypothalamic-pituitary-thyroid axis and alcohol craving in alcohol-dependent patients: a longitudinal study
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Alcohol Clin Exp Res 32:2047-53. 2008
    ..Investigating this association in alcohol-dependent (AD) patients was the aim of this preliminary and exploratory study...
  22. doi Renin and aldosterone but not the natriuretic peptide correlate with obsessive craving in medium-term abstinent alcohol-dependent patients: a longitudinal study
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Alcohol 42:375-81. 2008
    ..In conclusion, the renin-aldosterone axis could play a role in craving in medium-term abstinent patients and thereby leading to the hypothesis that alcohol craving could be influenced by the fluid volume intake...
  23. doi Quetiapine: treatment for substance abuse and drug of abuse
    Michael J Hanley
    University College of Pharmacy, Kingston, RI, USA
    Am J Health Syst Pharm 65:611-8. 2008
    ..The use of quetiapine as a drug to treat various substance use disorders as well as a drug of abuse is examined...
  24. doi Association of antipsychotic and antidepressant drugs with Q-T interval prolongation
    Wesley R Zemrak
    Brown Medical School, Brown University, Providence, RI, USA
    Am J Health Syst Pharm 65:1029-38. 2008
    ..The association of antipsychotic and antidepressant drugs with Q-T interval prolongation is reviewed...