Research Topics
Genomes and GenesSpecies | GEORGE KENNASummaryAffiliation: Brown University Country: USA Publications
Research Grants
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Detail Information
Publications
Substance use by pharmacy and nursing practitioners and students in a northeastern stateGeorge A Kenna
Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI, USA
Am J Health Syst Pharm 61:921-30. 2004..The prevalence and predictors of substance use among pharmacists and nurses and pharmacy and nursing students were studied...
The relationship of appetitive, reproductive and posterior pituitary hormones to alcoholism and craving in humansGeorge A Kenna
Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02912, USA
Neuropsychol Rev 22:211-28. 2012..Pharmacotherapies that take advantage of our new understanding of hormones, their receptors, or their potential relationship to craving may shed light on the treatment of this disorder...- Medications acting on the serotonergic system for the treatment of alcohol dependent patientsGeorge A Kenna
Box G S121 5, Brown University, Providence, RI 02912 Roger Williams Hospital USA
Curr Pharm Des 16:2126-35. 2010..Of course, future studies need to further delineate and confirm the differences between these alcoholic subtypes... - Review of topiramate: an antiepileptic for the treatment of alcohol dependenceGeorge A Kenna
Department of Psychiatry and Human Behavior, Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02908, USA
Curr Drug Abuse Rev 2:135-42. 2009..While the manufacturer will not pursue approval of an indication for the treatment of alcohol dependence, the drug will soon be available generically, making it more affordable for a greater proportion of the public... 
A safety and tolerability laboratory study of the combination of aripiprazole and topiramate in volunteers who drink alcoholGeorge A Kenna
Department of Psychiatry and the Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA
Hum Psychopharmacol 24:465-72. 2009..The ultimate aim for this research is to determine whether this combination is safe and is superior to either drug taken alone in reducing alcohol use in alcohol dependent patients...- A within-group design of nontreatment seeking 5-HTTLPR genotyped alcohol-dependent subjects receiving ondansetron and sertralineGeorge A Kenna
Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02908, USA
Alcohol Clin Exp Res 33:315-23. 2009..The aim of this study was to match and mismatch L/L, S/S, or S/L genotypes with administration of ondansetron and sertraline... - Risk factors for alcohol and other drug use by healthcare professionalsGeorge A Kenna
Center for Alcohol and Addiction Studies, Brown University, Box G 121S 4, Providence, RI 02908, USA
Subst Abuse Treat Prev Policy 3:3. 2008..Few studies have ever reported predictors or risk factors for alcohol and other drug use (AOD) across a sample of HPs... - Pharmacotherapy of dual substance abuse and dependenceGeorge A Kenna
Department of Community Health, Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA
CNS Drugs 21:213-37. 2007..While ondansetron and olanzapine show some efficacy in treating alcohol and cocaine dependence, more research is needed to better delineate the subpopulation in which these drugs may provide their maximum effect... - The prevalence of alcohol, cigarette and illicit drug use and problems among dentistsGeorge A Kenna
Community Health, Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02908, USA
J Am Dent Assoc 136:1023-32. 2005..The authors conducted a study to assess self-reported substance use by dentists and compare these data with those regarding physicians and the general population (GP)... - Alcohol use by healthcare professionalsGeorge A Kenna
Department of Psychiatry and Human Behavior, Brown University, Butler Hospital, Box G BH, Providence, RI 02912, USA
Drug Alcohol Depend 75:107-16. 2004..This study investigated alcohol use, misuse and abuse in a sample of dentists, nurses, pharmacists and physicians. Previous studies have lacked cross healthcare group comparisons and have rarely included dentists... - Can the short index of problems (SIP) be improved? Validity and reliability of the three-month SIP in an emergency department sampleGeorge A Kenna
Center for Alcohol and Addiction Studies, Brown University, Box G BH, Providence, Rhode Island 02908, USA
J Stud Alcohol 66:433-7. 2005.... - Prevalence of substance use by pharmacists and other health professionalsGeorge A Kenna
Department of Community Health, Brown University, Providence, RI 02908, USA
J Am Pharm Assoc (2003) 44:684-93. 2004.... - Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, part 1George A Kenna
Center for Alcohol and Addiction Studies, Brown University, Providence, RI, USA
Am J Health Syst Pharm 61:2272-9. 2004..The neurobiological basis of alcohol dependence, established pharmacotherapies for alcohol dependence, pharmacotherapies under investigation, and obstacles to treatment are discussed... - Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, Part 2George A Kenna
Center for Alcohol and Addiction Studies, Brown University, Providence, RI, USA
Am J Health Syst Pharm 61:2380-8. 2004..The neurobiological basis of alcohol dependence, established pharmacotherapies for alcohol dependence, pharmacotherapies under investigation, and obstacles to treatment are discussed... - New developments for the pharmacological treatment of alcohol withdrawal syndrome. A focus on non-benzodiazepine GABAergic medicationsLorenzo Leggio
Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI 02912, USA
Prog Neuropsychopharmacol Biol Psychiatry 32:1106-17. 2008..The promising results in terms of both safety and efficacy are reported. However, we also note the need of more methodologically controlled studies on a greater number of patients, involving more complicated forms of AWS... - Turning the clock ahead: potential preclinical and clinical neuropharmacological targets for alcohol dependenceLorenzo Leggio
Center for Alcohol and Addiction Studies, Brown University Medical School, Providence, RI 02912, USA
Curr Pharm Des 16:2159-18. 2010.... - HIV testing in hazardous drinking: a survey analysisMiriam Fenton
Department of Community Health, Brown University Medical School, Providence, Rhode Island 02912, USA
Subst Use Misuse 45:204-12. 2010..89) the odds of ever having had an HIV test compared to nonhazardous drinkers. Therefore public health interventions targeted at hazardous drinkers to increase the rate of HIV testing are suggested. The study's limitations are noted... - Blood glucose level, alcohol heavy drinking, and alcohol craving during treatment for alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) StudyLorenzo Leggio
Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02912, USA
Alcohol Clin Exp Res 33:1539-44. 2009..Heavy drinking may increase blood glucose levels. Moreover, in alcohol-dependent subjects, glucose may play a putative role in alcohol preference... - Typologies of alcohol dependence. From Jellinek to genetics and beyondLorenzo Leggio
Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Box G S 121 4, Providence, RI 02912, USA
Neuropsychol Rev 19:115-29. 2009..Greater emphasis, however, must be made to more clearly delineate this field of research, while moving toward more standardized typologies... - Relationship between the hypothalamic-pituitary-thyroid axis and alcohol craving in alcohol-dependent patients: a longitudinal studyLorenzo Leggio
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Alcohol Clin Exp Res 32:2047-53. 2008..Investigating this association in alcohol-dependent (AD) patients was the aim of this preliminary and exploratory study... - Quetiapine: treatment for substance abuse and drug of abuseMichael J Hanley
University College of Pharmacy, Kingston, RI, USA
Am J Health Syst Pharm 65:611-8. 2008..The use of quetiapine as a drug to treat various substance use disorders as well as a drug of abuse is examined... - Renin and aldosterone but not the natriuretic peptide correlate with obsessive craving in medium-term abstinent alcohol-dependent patients: a longitudinal studyLorenzo Leggio
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Alcohol 42:375-81. 2008..In conclusion, the renin-aldosterone axis could play a role in craving in medium-term abstinent patients and thereby leading to the hypothesis that alcohol craving could be influenced by the fluid volume intake... - Association of antipsychotic and antidepressant drugs with Q-T interval prolongationWesley R Zemrak
Brown Medical School, Brown University, Providence, RI, USA
Am J Health Syst Pharm 65:1029-38. 2008..The association of antipsychotic and antidepressant drugs with Q-T interval prolongation is reviewed...
Research Grants
- Matching 5-HT Genotypes to Serotonergic Medications for AlcoholismGEORGE KENNA; Fiscal Year: 2007....
- Matching 5-HT Genotypes to Serotonergic Medications for AlcoholismGEORGE KENNA; Fiscal Year: 2009....
- Matching 5-HT Genotypes to Serotonergic Medications for AlcoholismGEORGE ANTHONY KENNA; Fiscal Year: 2010....