Jon E Grant

Summary

Affiliation: Brown University
Country: USA

Publications

  1. doi A Structured Clinical Interview for Kleptomania (SCI-K): preliminary validity and reliability testing
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Int J Methods Psychiatr Res 15:83-94. 2006
  2. pmc Is anorexia nervosa a subtype of body dysmorphic disorder? Probably not, but read on
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School Butler Hospital, Providence, RI, USA
    Harv Rev Psychiatry 12:123-6. 2004
  3. ncbi Quality of life in kleptomania and pathological gambling
    Jon E Grant
    Department of Psychiatry, Brown Medical School Butler Hospital, Providence, RI 02906, USA
    Compr Psychiatry 46:34-7. 2005
  4. ncbi Outcome study of kleptomania patients treated with naltrexone: a chart review
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School and Butler Hospital, Providence, Rhode Island 02906, USA
    Clin Neuropharmacol 28:11-4. 2005
  5. ncbi Co-occurrence of personality disorders in persons with kleptomania: a preliminary investigation
    Jon E Grant
    Department of Psychiatry and Human Behavior, Butler Hospital and Brown Medical School, Providence, RI 02906, USA
    J Am Acad Psychiatry Law 32:395-8. 2004
  6. ncbi Pharmacotherapy outcome in older pathological gamblers: a preliminary investigation
    Jon E Grant
    Department of Psychiatry and Human Behavior, Butler Hospital and Brown Medical School, 345 Blackstone Blvd, Providence, RI 02906, USA
    J Geriatr Psychiatry Neurol 17:9-12. 2004
  7. ncbi Preliminary validity and reliability testing of a structured clinical interview for pathological gambling
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Psychiatry Res 128:79-88. 2004
  8. ncbi Dissociative symptoms in kleptomania
    Jon E Grant
    Department of Psychiatry and Human Behavior, Butler Hospital Brown Medical School, 345 Blackstone Blvd, Providence, RI 02906, USA
    Psychol Rep 94:77-82. 2004
  9. ncbi Impulse control disorders: clinical characteristics and pharmacological management
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, Rhode Island 02906, USA
    Ann Clin Psychiatry 16:27-34. 2004
  10. pmc Substance use disorders in individuals with body dysmorphic disorder
    Jon E Grant
    Butler Hospital and the Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    J Clin Psychiatry 66:309-16; quiz 404-5. 2005

Detail Information

Publications99

  1. doi A Structured Clinical Interview for Kleptomania (SCI-K): preliminary validity and reliability testing
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Int J Methods Psychiatr Res 15:83-94. 2006
    ..These findings require replication in larger groups, including non-psychiatric populations, to examine their generalizability...
  2. pmc Is anorexia nervosa a subtype of body dysmorphic disorder? Probably not, but read on
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School Butler Hospital, Providence, RI, USA
    Harv Rev Psychiatry 12:123-6. 2004
  3. ncbi Quality of life in kleptomania and pathological gambling
    Jon E Grant
    Department of Psychiatry, Brown Medical School Butler Hospital, Providence, RI 02906, USA
    Compr Psychiatry 46:34-7. 2005
    ..32; df = 58; P < .001; t = 7.32; df = 71; P < .001, respectively). These results suggest that patients with kleptomania and pathological gamblers have notably poor quality of life...
  4. ncbi Outcome study of kleptomania patients treated with naltrexone: a chart review
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School and Butler Hospital, Providence, Rhode Island 02906, USA
    Clin Neuropharmacol 28:11-4. 2005
    ..This study examines the response to treatment in 17 patients with kleptomania who were treated with naltrexone as monotherapy for up to 3 years...
  5. ncbi Co-occurrence of personality disorders in persons with kleptomania: a preliminary investigation
    Jon E Grant
    Department of Psychiatry and Human Behavior, Butler Hospital and Brown Medical School, Providence, RI 02906, USA
    J Am Acad Psychiatry Law 32:395-8. 2004
    ..Persons with kleptomania appear to have a high prevalence of personality disorders. Further studies are needed to understand the relationship of kleptomania to personality...
  6. ncbi Pharmacotherapy outcome in older pathological gamblers: a preliminary investigation
    Jon E Grant
    Department of Psychiatry and Human Behavior, Butler Hospital and Brown Medical School, 345 Blackstone Blvd, Providence, RI 02906, USA
    J Geriatr Psychiatry Neurol 17:9-12. 2004
    ..The present findings indicate that many older pathological gamblers respond to "off-label" use of pharmacotherapy. The present findings are preliminary. Further studies with larger samples are needed to confirm these findings...
  7. ncbi Preliminary validity and reliability testing of a structured clinical interview for pathological gambling
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Psychiatry Res 128:79-88. 2004
    ..The SCI-PG demonstrated excellent reliability and validity in diagnosing PG in subjects presenting with gambling problems. These findings require replication in other groups to examine their generalizability...
  8. ncbi Dissociative symptoms in kleptomania
    Jon E Grant
    Department of Psychiatry and Human Behavior, Butler Hospital Brown Medical School, 345 Blackstone Blvd, Providence, RI 02906, USA
    Psychol Rep 94:77-82. 2004
    ..There were no statistically significant differences by sex. Because kleptomania patients seeking treatment with medication may differ from others with kleptomania, further studies are needed...
  9. ncbi Impulse control disorders: clinical characteristics and pharmacological management
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, Rhode Island 02906, USA
    Ann Clin Psychiatry 16:27-34. 2004
    ....
  10. pmc Substance use disorders in individuals with body dysmorphic disorder
    Jon E Grant
    Butler Hospital and the Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    J Clin Psychiatry 66:309-16; quiz 404-5. 2005
    ..Little is known about substance use disorders (SUDs) in individuals with body dysmorphic disorder (BDD). Although studies have examined SUD comorbidity in BDD, no previous studies have examined clinical correlates of SUD comorbidity...
  11. ncbi Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Am J Psychiatry 163:303-12. 2006
    ..The authors examined the efficacy and tolerability of the opioid antagonist nalmefene in the treatment of adults with pathological gambling...
  12. pmc Prevalence and correlates of fire-setting in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
    Carlos Blanco
    Department of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Box 69, New York, NY 10032, USA
    J Clin Psychiatry 71:1218-25. 2010
    ..To estimate the prevalence, sociodemographic correlates, comorbidity, and rates of mental health service utilization of fire-setters in the general population...
  13. pmc Strategic vs nonstrategic gambling: characteristics of pathological gamblers based on gambling preference
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
    Ann Clin Psychiatry 23:105-12. 2011
    ..Although prior studies have examined various clinical characteristics of pathological gambling (PG), limited data exist regarding the clinical correlates of PG based on preferred forms of gambling...
  14. doi Characteristics of pathological gamblers with a problem gambling parent
    Liana Schreiber
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454, USA
    Am J Addict 18:462-9. 2009
    ..Treatment approaches may need to be tailored for specific problems secondary to gambling and gender issues based on the history of having a problem gambling parent...
  15. pmc Relationship of nicotine dependence, subsyndromal and pathological gambling, and other psychiatric disorders: data from the National Epidemiologic Survey on Alcohol and Related Conditions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 70:334-43. 2009
    ..Nicotine dependence frequently co-occurs with subsyndromal and pathological levels of gambling. The relationship of nicotine dependence, levels of gambling pathology, and other psychiatric disorders, however, is incompletely understood...
  16. pmc Substance use disorders in an obsessive compulsive disorder clinical sample
    Maria C Mancebo
    Butler Hospital, Providence, RI 02906, USA
    J Anxiety Disord 23:429-35. 2009
    ..Individuals with a juvenile-onset of OCD or comorbid BPD may be especially vulnerable to SUDs. Further research is needed to identify risk factors for SUDs and to better understand their impact on OCD course...
  17. pmc Late-onset pathological gambling: clinical correlates and gender differences
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Psychiatr Res 43:380-7. 2009
    ..Late-onset PG is relatively common and has distinct clinical characteristics suggesting that this population might benefit from unique prevention and treatment strategies...
  18. ncbi Late-onset obsessive compulsive disorder: clinical characteristics and psychiatric comorbidity
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatry Res 152:21-7. 2007
    ....
  19. doi Neurocognitive deficits associated with shoplifting in young adults
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    Compr Psychiatry 53:1049-55. 2012
    ..Shoplifting is a relatively common behavior in young adults, but the demographic and neuropsychological correlates of shoplifting remain poorly characterized in this context...
  20. doi Cognitive task performance and frequency of alcohol usage in young adults
    Arit M Harvanko
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    J Addict Med 6:106-11. 2012
    ..The goal of our study was to examine cognitive effects of alcohol in young adults at varied levels of alcohol usage using well-validated computerized cognitive measures...
  21. pmc Correlates of occupational disability in a clinical sample of obsessive-compulsive disorder
    Maria C Mancebo
    Butler Hospital, Providence, RI 02906, USA
    Compr Psychiatry 49:43-50. 2008
    ..This study aimed to examine correlates of occupational disability in a large, clinical sample of individuals with a primary diagnosis of obsessive-compulsive disorder (OCD)...
  22. pmc Predicting response to opiate antagonists and placebo in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 200:521-7. 2008
    ..No studies have systematically examined predictors of medication treatment outcome in PG. Understanding clinical variables related to treatment outcome should help generate treatment algorithms for PG...
  23. pmc The Gambling Symptom Assessment Scale (G-SAS): a reliability and validity study
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Psychiatry Res 166:76-84. 2009
    ..The correlations between the G-SAS and the PG-YBOCS and Clinical Global Impression rating were excellent. Findings suggest that the G-SAS is reliable and valid in assessing changes in symptoms during a drug treatment study...
  24. pmc A double-blind, placebo-controlled trial of lamotrigine for pathological skin picking: treatment efficacy and neurocognitive predictors of response
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    J Clin Psychopharmacol 30:396-403. 2010
    ..However, these neurocognitive data suggest that lamotrigine may be valuable in a subset of patients who exhibit relatively impaired cognitive flexibility...
  25. ncbi N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Biol Psychiatry 62:652-7. 2007
    ..N-acetyl cysteine (NAC), an amino acid, seems to restore extracellular glutamate concentration in the nucleus accumbens and therefore offers promise in reducing addictive behavior...
  26. doi Pathologic skin picking
    Brian L Odlaug
    University of Minnesota, Ambulatory Research Center, Department of Psychiatry, Minneapolis, USA
    Am J Drug Alcohol Abuse 36:296-303. 2010
    ..Pathologic skin picking (PSP) is characterized by the repetitive and compulsive picking of skin which results in tissue damage...
  27. doi Quality of life and clinical severity in pathological skin picking and trichotillomania
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    J Anxiety Disord 24:823-9. 2010
    ..Quality of life was not associated with symptom severity. Larger studies should examine further the impact PSP and TTM have on quality of life as well as the role quality of life itself plays in the severity and duration of illness...
  28. pmc Shopping problems among high school students
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 52:247-52. 2011
    ..An assessment of adolescent shopping behavior along a continuum of severity and its relationship to other behaviors and health issues is incompletely understood...
  29. ncbi Impulse control disorders in adults with obsessive compulsive disorder
    Jon E Grant
    Butler Hospital and the Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    J Psychiatr Res 40:494-501. 2006
    ..These preliminary results suggest that there is a low prevalence of ICDs among individuals with OCD, although certain ICDs (skin picking) appear to be more common...
  30. pmc Memantine shows promise in reducing gambling severity and cognitive inflexibility in pathological gambling: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 212:603-12. 2010
    ..Memantine, an N-methyl D-aspartate receptor antagonist, appears to reduce glutamate excitability and improve impulsive decision making, suggesting it may help individuals with PG...
  31. pmc Neurocognitive dysfunction in strategic and non-strategic gamblers
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 38:336-40. 2012
    ..Whether or not putative pathological gambling subtypes differ in terms of their clinical and cognitive profiles has received little attention...
  32. doi A cognitive comparison of pathological skin picking and trichotillomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    J Psychiatr Res 45:1634-8. 2011
    ..The extent to which these disorders share a common cognitive phenotype, however, has yet to be examined. This study sought to compare inhibitory control processes in individuals with PSP or TTM...
  33. doi Dronabinol, a cannabinoid agonist, reduces hair pulling in trichotillomania: a pilot study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 218:493-502. 2011
    ..Trichotillomania is characterized by repetitive pulling causing noticeable hair loss. Pharmacological treatment data for trichotillomania are limited...
  34. doi A clinical comparison of pathologic skin picking and obsessive-compulsive disorder
    Jon E Grant
    Department of Psychiatry, Ambulatory Research Center, University of Minnesota Medical Center, Minneapolis, MN 55454, USA
    Compr Psychiatry 51:347-52. 2010
    ..This study sought to examine the clinical similarities between PSP and OCD...
  35. ncbi A double-blind, placebo-controlled study of the opiate antagonist naltrexone in the treatment of pathological gambling urges
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    J Clin Psychiatry 69:783-9. 2008
    ..This study examined the efficacy and tolerability of the opioid antagonist naltrexone in adults with PG who have urges to gamble...
  36. ncbi Childhood-onset pathologic skin picking: clinical characteristics and psychiatric comorbidity
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Compr Psychiatry 48:388-93. 2007
    ....
  37. pmc Pathological skin picking in individuals with body dysmorphic disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Gen Hosp Psychiatry 28:487-93. 2006
    ..The objective of this study was to examine the prevalence and clinical correlates of pathological skin picking (PSP) in a large sample of individuals with body dysmorphic disorder (BDD)...
  38. pmc Sexual orientation of men with pathological gambling: prevalence and psychiatric comorbidity in a treatment-seeking sample
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 47:515-8. 2006
    ..04). Psychiatric comorbidity and impairment are high in gay and bisexual men with PG. Research is needed to optimize patient care for gay and bisexual men with PG...
  39. doi Prevalence, correlates, and comorbidity of DSM-IV obsessive-compulsive personality disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    J Psychiatr Res 46:469-75. 2012
    ..The results highlight the need for further research to identify common pathophysiological elements common to OCPD and associated disorders...
  40. ncbi Examination of gender in pathologic grooming behaviors
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatr Q 78:259-67. 2007
    ..Further research is needed to validate our findings and identify whether treatments should be specially tailored differently for men and women with grooming disorders...
  41. ncbi Lamotrigine treatment of pathologic skin picking: an open-label study
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1384-91. 2007
    ..Although pathologic skin picking is a relatively common behavior, treatment data are limited. We hypothesized that lamotrigine would reduce the symptoms of pathologic skin picking...
  42. ncbi Frontal white matter integrity in borderline personality disorder with self-injurious behavior
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical Center, University of Minnesota, Minneapolis, MN, USA
    J Neuropsychiatry Clin Neurosci 19:383-90. 2007
    ..Women with borderline personality disorder-self-injurious behavior exhibit decreased white matter microstructural integrity in inferior frontal brain regions that may include components of orbito-frontal circuitry...
  43. doi A double-blind, placebo-controlled study of the opiate antagonist, naltrexone, in the treatment of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Biol Psychiatry 65:600-6. 2009
    ..This study examined the efficacy and tolerability of the opioid antagonist naltrexone in adults with kleptomania who have urges to steal...
  44. doi Legal consequences of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychiatr Q 80:251-9. 2009
    ..Kleptomania is associated with significant legal repercussions. The findings emphasize the need for rigorous treatment approaches to target kleptomania symptoms and prevent re-offending...
  45. doi Motor inhibition and cognitive flexibility in pathologic skin picking
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 34:208-11. 2010
    ..This study sought to assess motor inhibitory control and aspects of cognitive flexibility in a sample of individuals with PSP...
  46. pmc Impulse-control disorders in children and adolescents with obsessive-compulsive disorder
    Jon E Grant
    Butler Hospital and the Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    Psychiatry Res 175:109-13. 2010
    ..Certain ICDs are common among children and adolescents with OCD. Better identification of ICDs in children and adolescents with OCD is needed, as are empirically validated treatments for youth with co-occurring ICDs...
  47. pmc A 6-month follow-up of imaginal desensitization plus motivational interviewing in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 23:3-10. 2011
    ..This study sought to examine whether those benefits were maintained 6 months post-treatment...
  48. doi Cigarette smoking status in pathological gamblers: association with impulsivity and cognitive flexibility
    Marc E Mooney
    University of Minnesota, Department of Psychiatry, Minneapolis, MN 55454, USA
    Drug Alcohol Depend 117:74-7. 2011
    ..This study evaluated impulsivity and cognitive flexibility in a sample of pathological gamblers with differing smoking status...
  49. doi Nalmefene in the treatment of pathological gambling: multicentre, double-blind, placebo-controlled study
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Br J Psychiatry 197:330-1. 2010
    ..These findings suggest that medication dosing may be an important consideration in achieving symptom control...
  50. ncbi Safety of high-dose naltrexone treatment: hepatic transaminase profiles among outpatients
    Suck Won Kim
    Department of Psychiatry, Medical School, University of Minnesota, Minneapolis, 55454 1495, USA
    Clin Neuropharmacol 29:77-9. 2006
    ..This study was carried out to test the hypothesis that the hepatic safety profile of prolonged high-dose oral naltrexone (150 mg/d) is acceptable if over-the-counter analgesic use is restricted...
  51. ncbi An open-label study of naltrexone in the treatment of kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis 55454 1495, USA
    J Clin Psychiatry 63:349-56. 2002
    ..The present study was designed to test the short-term efficacy and safety of naltrexone in the treatment of kleptomania...
  52. ncbi Pathological gambling and mood disorders: clinical associations and treatment implications
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, F282 2A West, 2450 Riverside Avenue, Minneapolis, 55454, USA
    J Affect Disord 92:109-16. 2006
    ..Traditionally, mood and gambling symptoms have been known to overlap. In the present review we attempt to examine the diagnostic associations and implications for treatment...
  53. ncbi Sexual obsessions and clinical correlates in adults with obsessive-compulsive disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, 55454, USA
    Compr Psychiatry 47:325-9. 2006
    ..These preliminary results suggest that sexual obsessions are fairly common among individuals with OCD and may be associated with important clinical characteristics...
  54. ncbi Clinical characteristics and psychiatric comorbidity in males with exhibitionism
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School and Butler Hospital, Providence, R I, USA
    J Clin Psychiatry 66:1367-71. 2005
    ..This study was constructed to detail the demographic and phenomenological features of males with exhibitionism...
  55. ncbi Advances in the pharmacological treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454 1495, USA
    J Gambl Stud 19:85-109. 2003
    ..We also discuss dosage strategies, the duration of treatment, issues surrounding medication compliance, and approaches to treatment-refractory pathological gambling, such as pharmacological and behavioral augmentation...
  56. doi Personality disorders and dimensions in pathological gambling
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
    J Pers Disord 26:381-92. 2012
    ..Further exploration of these disorders and dimensions of personality may encourage a more inclusively global treatment approach...
  57. ncbi Escitalopram treatment of pathological gambling with co-occurring anxiety: an open-label pilot study with double-blind discontinuation
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454, USA
    Int Clin Psychopharmacol 21:203-9. 2006
    ..Larger, longer, placebo-controlled, double-blind studies are needed to evaluate further the safety and tolerability of escitalopram in the treatment of PG and co-occurring anxiety...
  58. ncbi Update on pathological skin picking
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Curr Psychiatry Rep 11:283-8. 2009
    ..Although the disorder is common, appropriate treatments for PSP are limited. Pharmacotherapeutic and certain cognitive-behavioral interventions have demonstrated promise in treating this disorder and need to be explored further...
  59. ncbi N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Arch Gen Psychiatry 66:756-63. 2009
    ..N-acetylcysteine, an amino acid, seems to restore the extracellular glutamate concentration in the nucleus accumbens and, therefore, offers promise in the reduction of compulsive behavior...
  60. pmc Pathologic gambling and bankruptcy
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Compr Psychiatry 51:115-20. 2010
    ..Although prior studies have examined rates of bankruptcy in pathologic gambling (PG), there are only limited data regarding the clinical correlates of those with PG who declare bankruptcy because of gambling...
  61. ncbi Augmentation with naltrexone to treat compulsive sexual behavior: a case series
    Nancy C Raymond
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 22:56-62. 2010
    ..We hypothesized that naltrexone would reduce the urges and behaviors associated with CSB...
  62. pmc Pharmacological treatment of adolescent pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Int J Adolesc Med Health 22:129-38. 2010
    ....
  63. ncbi Clinical characteristics and associated psychopathology of 22 patients with kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454 1495, USA
    Compr Psychiatry 43:378-84. 2002
    ..We conclude that kleptomania is a distressing and disabling disorder associated with high rates of psychiatric comorbidity...
  64. ncbi A double-blind placebo-controlled study of the efficacy and safety of paroxetine in the treatment of pathological gambling
    Suck Won Kim
    Department of Psychiatry, University of Minnesota, Minneapolis, USA
    J Clin Psychiatry 63:501-7. 2002
    ..This randomized, double-blind, placebo-controlled study investigated the efficacy and tolerability of paroxetine in the treatment of pathological gambling...
  65. ncbi Update on pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Curr Psychiatry Rep 8:53-8. 2006
    ..Although PG is a disabling disorder that continues to represent a clinical challenge for the healthcare professional, our current knowledge of pharmacotherapy and psychosocial interventions offers potentially effective treatment options...
  66. pmc Emotion regulation and impulsivity in young adults
    Liana R N Schreiber
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, MN, USA
    J Psychiatr Res 46:651-8. 2012
    ....
  67. ncbi Clinical characteristics and psychiatric comorbidity of pyromania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1717-22. 2007
    ..This study details the demographic and phenomenological features of individuals with DSM-IV lifetime pyromania...
  68. ncbi Paroxetine treatment of pathological gambling: a multi-centre randomized controlled trial
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55454 1495, USA
    Int Clin Psychopharmacol 18:243-9. 2003
    ..Paroxetine consistently demonstrated an advantage over placebo on the Clinical Global Impressions scale; however, a larger sample size may have registered significant differences...
  69. ncbi Pathological gambling. Current status and new treatments
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, USA
    Minn Med 85:48-50, 52. 2002
    ..A brief clinical description of PGD is followed by a summary of published drug treatment outcomes and the basic principles of medication treatment in office practice...
  70. doi Clinical characteristics and medical complications of pathologic skin picking
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Gen Hosp Psychiatry 30:61-6. 2008
    ..This study sought to detail the phenomenology and medical consequences of pathologic skin picking (PSP)...
  71. ncbi Effectiveness of pharmacotherapy for pathological gambling: a chart review
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454 1495, USA
    Ann Clin Psychiatry 14:155-61. 2002
    ..Naltrexone, or augmentation of naltrexone with an SSRI, appears to be most effective in relieving gambling symptoms...
  72. ncbi Gender differences in pathological gamblers seeking medication treatment
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Ave, Minneapolis, MN 55454 1495, USA
    Compr Psychiatry 43:56-62. 2002
    ..There appear to be some gender differences in the clinical features of PGD, and these differences may have treatment implications...
  73. ncbi Temperament and early environmental influences in kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis 55454 1495, USA
    Compr Psychiatry 43:223-8. 2002
    ..These findings suggest that an understanding of early parenting behavior and a dimensional approach to the personality of kleptomaniacs may offer insight into this disorder and provide clues to treatment strategies...
  74. pmc Recognizing and treating body dysmorphic disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 17:205-10. 2005
    ..Body dysmorphic disorder (BDD) is a relatively common and often-disabling obsessive compulsive spectrum disorder that often goes unrecognized in clinical practice...
  75. pmc A retrospective follow-up study of body dysmorphic disorder
    Katharine A Phillips
    Butler Hospital, Providence, RI 02906, USA
    Compr Psychiatry 46:315-21. 2005
    ..Although research on body dysmorphic disorder (BDD) is increasing, no follow-up studies of this disorder's course of illness have been published...
  76. ncbi Body dysmorphic disorder in patients with anorexia nervosa: prevalence, clinical features, and delusionality of body image
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Int J Eat Disord 32:291-300. 2002
    ..We hypothesized that body dysmorphic disorder would be underdiagnosed in patients with anorexia nervosa and that comorbidity with body dysmorphic disorder would result in greater overall dysfunction...
  77. ncbi Understanding and treating kleptomania: new models and new treatments
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Isr J Psychiatry Relat Sci 43:81-7. 2006
    ..Subtyping of individuals with kleptomania may be a useful way to better understand this behavior and decide on effective treatment interventions...
  78. ncbi Dissociative symptoms in pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopathology 36:200-3. 2003
    ..The purpose of this investigation was to shed light on a possible link between dissociation and pathological gambling, a relatively common disorder whose phenomenology remains understudied...
  79. ncbi Tobacco use and pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 17:237-41. 2005
    ..An improved understanding of the relationship would be helpful in treating individuals with co-occurring pathological gambling and nicotine dependence...
  80. ncbi Family history and psychiatric comorbidity in persons with kleptomania
    Jon E Grant
    Department of Psychiatry, Brown Medical School and Butler Hospital, Providence, RI 02906, USA
    Compr Psychiatry 44:437-41. 2003
    ..056; df=1; P=.001). Persons with kleptomania appear to have a higher lifetime prevalence of impulse-control disorders and are more likely to have first-degree relatives with alcohol problems than are comparison subjects...
  81. ncbi Impulse-control disorders in adolescent psychiatric inpatients: co-occurring disorders and sex differences
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1584-92. 2007
    ..To examine in a sex-sensitive manner the frequencies, clinical correlates, and patterns of co-occurrence of impulse-control disorders in adolescent psychiatric inpatients...
  82. pmc Clinical characteristics of trichotillomania with trichophagia
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 49:579-84. 2008
    ..Little is known about trichophagia in individuals with trichotillomania. Although studies have mentioned the behavior, no previous studies have examined clinical correlates of trichophagia...
  83. ncbi Retrospective review of treatment retention in pathological gambling
    Jon E Grant
    Department of Psychiatry, Brown University, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Compr Psychiatry 45:83-7. 2004
    ..Predictors of treatment continuation may have clinical importance. Prospective longitudinal studies are needed to further elucidate the course of pathological gambling...
  84. pmc Gender-related differences in individuals seeking treatment for kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    CNS Spectr 13:235-45. 2008
    ..Few empirical investigations have been performed in kleptomania, particularly with respect to gender-related influences...
  85. pmc Compulsive aspects of impulse-control disorders
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue Minneapolis, MN 55454, USA
    Psychiatr Clin North Am 29:539-51, x. 2006
    ..The construct of compulsivity as related to ICDs and OCD warrants additional investigation to identify the similarities and differences and to examine the implications for prevention and treatment strategies...
  86. pmc Medication management of pathological gambling
    Jon E Grant
    University of Minnesota Medical School, USA
    Minn Med 89:44-8. 2006
    ....
  87. ncbi Addicted to hair pulling? How an alternate model of trichotillomania may improve treatment outcome
    Jon E Grant
    Psychiatry Department, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Harv Rev Psychiatry 15:80-5. 2007
  88. ncbi Reliability and validity of the pathological gambling adaptation of the Yale-Brown Obsessive-Compulsive Scale (PG-YBOCS)
    Stefano Pallanti
    Mount Sinai School of Medicine, New York, NY 10029, USA
    J Gambl Stud 21:431-43. 2005
    ..PG-YBOCS thus appears to be a reliable and valid measure of pathological gambling severity, and can be regarded as an important tool for clinicians and researchers treating pathological gamblers...
  89. ncbi Impulse control disorders in adult psychiatric inpatients
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN 55454
    Am J Psychiatry 162:2184-8. 2005
    ..The authors' goal was to examine the prevalence of impulse control disorders in psychiatric inpatients...
  90. ncbi Betting on dopamine
    Dan J Stein
    University of Stellenbosch, Cape Town, South Africa
    CNS Spectr 10:268-70. 2005
  91. ncbi [Kleptomania: clinical characteristics and treatment]
    Jon E Grant
    Departmento de Psiquiatria, School of Medicine, University of Minnesota, Minnesota 55454, USA
    Rev Bras Psiquiatr 30:S11-5. 2008
    ..Despite its relatively long history, kleptomania remains poorly understood to the general public, clinicians, and sufferers...
  92. ncbi Alcohol craving in outpatients with alcohol dependence: rate and clinical correlates
    Gihyun Yoon
    Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota 55417, USA
    J Stud Alcohol 67:770-7. 2006
    ..We also examined the relationship between alcohol craving and the clinical characteristics of alcohol-dependent patients...
  93. ncbi The neurobiology of substance and behavioral addictions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    CNS Spectr 11:924-30. 2006
    ....
  94. ncbi Commentary: illegal behavior and pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN, USA
    J Am Acad Psychiatry Law 35:302-5. 2007
    ..Although the article by Ledgerwood and colleagues provides additional insight into the relationship between pathological gambling and illegal behavior, many questions remain unanswered and warrant further investigation...
  95. ncbi Trichotillomania and Pathologic Skin Picking: clinical comparison with an examination of comorbidity
    Brian L Odlaug
    Department of Psychiatry, University of Minnesota Medical Center, Minneapolis, Minnesota 55454, USA
    Ann Clin Psychiatry 20:57-63. 2008
    ..We sought to examine the similarities and differences between these three groups from a clinical viewpoint...
  96. ncbi Sex differences in pain and hypothalamic-pituitary-adrenocortical responses to opioid blockade
    Mustafa al'Absi
    Department of Behavioral Sciences, University of Minnesota School of Medicine, Duluth, Minnesota 55812, USA
    Psychosom Med 66:198-206. 2004
    ..Little is known about the role of the endogenous opioid system in these differences. This study was conducted to compare adrenocortical, pain sensitivity, and blood pressure responses to opioid blockade using naltrexone in men and women...
  97. pmc Naltrexone effect on physiological and subjective response to a cold pressor task
    Michael Kotlyar
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, 7 170 Weaver Densford Hall, 308 Harvard St SE, Minneapolis, MN 55455, United States
    Biol Psychol 77:233-6. 2008
    ..No significant differences were found for other measures assessed. Further research is necessary to determine the subpopulations in which these effects are of greatest magnitude and the long term safety implications of these effects...
  98. ncbi Neuropsychological functioning in kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Behav Res Ther 45:1663-70. 2007
    ..693, p=0.004). As a group, subjects with kleptomania did not demonstrate deficits on neuropsychological testing. Greater kleptomania symptom severity, however, was correlated with impairment in executive functioning...
  99. ncbi Parental bonding in pathological gambling disorder
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454 1495, USA
    Psychiatr Q 73:239-47. 2002
    ..These preliminary findings suggest that neglectful parenting appears to be associated with pathological gambling disorder...