Research Topics
| DANIEL DICKSTEINSummaryAffiliation: Brown University Country: USA Publications
Research Grants
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Detail Information
Publications
Developmental meta-analysis of the functional neural correlates of autism spectrum disordersDaniel P Dickstein
Bradley Hospital s PediMIND Program, East Providence, RI 02915, USA
J Am Acad Child Adolesc Psychiatry 52:279-289.e16. 2013..We hypothesized that children and adolescents with ASD (<18 years old) would rely less on prefrontal cortex structures than adults (≥18 years old)...- Proton magnetic resonance spectroscopy in youth with severe mood dysregulationDaniel P Dickstein
Unit on Bipolar Spectrum Disorders, Division of Intramural Research Programs, National Institute of Mental Health, Bethesda, MD, USA
Psychiatry Res 163:30-9. 2008.... 
Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulationDaniel P Dickstein
E P Bradley Hospital, Bradley Hasbro Children s Research Center, 1 Hoppin ST Coro West, Providence, RI 02903, USA
J Child Adolesc Psychopharmacol 19:61-73. 2009..We conducted the first randomized double-blind, placebo-controlled trial in SMD youth, choosing lithium on the basis of its potential in treating irritability and aggression and neuro-metabolic effects...- Affect regulation in pediatric bipolar disorderDaniel P Dickstein
Pediatric Mood, Imaging, and Neurodevelopment Program, EP Bradley Hospital, Bradley Hasbro Children s Research Center, Warren Alpert Medical School of Brown University, 1 Hoppin Street, Providence, RI 02903, USA
Child Adolesc Psychiatr Clin N Am 18:405-20, ix. 2009..quot; The present article reviews the current understanding of affect regulation. The authors also discuss recent findings implicating affect dysregulation in children and adolescents with bipolar disorder... - Impaired probabilistic reversal learning in youths with mood and anxiety disordersD P Dickstein
National Institute of Mental Health NIMH Mood and Anxiety Disorders Program
Psychol Med 40:1089-100. 2010.... - Fronto-temporal spontaneous resting state functional connectivity in pediatric bipolar disorderDaniel P Dickstein
Bradley Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, USA
Biol Psychiatry 68:839-46. 2010..We now report the first use of task-independent spontaneous resting state functional connectivity (RSFC) to study the neural underpinnings of pediatric BD... - Altered neural function in pediatric bipolar disorder during reversal learningDaniel P Dickstein
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
Bipolar Disord 12:707-19. 2010..Here, we use event-related functional magnetic resonance imaging (fMRI) to elucidate neural correlates of reversal learning deficits in euthymic BD youth compared to typically developing controls... - Face processing in attention deficit/hyperactivity disorderDaniel P Dickstein
PediMIND Program, E P Bradley Hospital, Alpert Medical School of Brown University, East Providence, USA
Curr Top Behav Neurosci 9:219-37. 2012..Here, we review the neurobiology of face processing and suggest that face-processing alterations offer a window into the emotional dysfunction often accompanying ADHD... 
Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorderEllen Leibenluft
Emotion and Development Branch, Mood and Anxiety Disorders Program, NIMH, NIH, Health and Human Services, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
Am J Psychiatry 164:52-60. 2007..They also compared activation in medicated versus unmedicated children with bipolar disorder and in children with bipolar disorder and attention deficit hyperactivity disorder (ADHD) versus those with bipolar disorder without ADHD...- Brain systems underlying response flexibility in healthy and bipolar adolescents: an event-related fMRI studyEric E Nelson
Mood and Anxiety Disorders Program, National Institute of Mental Health, Building 106 C, 5413 W Cedar Lane, Bethesda, MD 20892, USA
Bipolar Disord 9:810-9. 2007..The present study was undertaken to determine if neuronal responses differed between BD and control subjects on a simple motor response flexibility task... - Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry studyDaniel P Dickstein
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
Arch Gen Psychiatry 62:734-41. 2005..While numerous magnetic resonance imaging (MRI) studies have evaluated adults with bipolar disorder (BPD), few have examined MRI changes in children with BPD... - Neural connectivity in children with bipolar disorder: impairment in the face emotion processing circuitBrendan A Rich
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda 20892 2670, MD, USA
J Child Psychol Psychiatry 49:88-96. 2008.... - Emotion regulation in children and adolescents: boundaries between normalcy and bipolar disorderDaniel P Dickstein
Mood and Anxiety Disorder Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
Dev Psychopathol 18:1105-31. 2006..Taken as a whole, this work implicates a neural circuit encompassing the prefrontal cortex, amygdala, and striatum in the pathophysiology of pediatric BD... - Neural activation during encoding of emotional faces in pediatric bipolar disorderDaniel P Dickstein
Division of Intramural Research Program, National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, Bethesda, MD 20892 2670, USA
Bipolar Disord 9:679-92. 2007..To begin to address these limitations, the current study tests the hypothesis that pediatric BD (PBD) subjects exhibit altered neural activation during encoding of emotional faces compared to typically developing controls... - Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulationMelissa A Brotman
Emotion and Development Branch and the Genetic Basis of Mood and Anxiety Disorders Unit, Mood and Anxiety Disorders Program, NIMH, NIH, Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Psychiatry 164:1238-41. 2007..The authors compared axis I diagnoses in parents of children with narrow phenotype bipolar disorder and parents of youth with severe mood dysregulation... - Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disordersMelissa A Brotman
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Biol Psychiatry 61:819-21. 2007..Although comorbid anxiety disorders are common in children with bipolar disorder (BD), it is unclear how this comorbidity impacts the pathophysiology of the illness... - Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorderTristan Gorrindo
Mood and Anxiety Program, National Institute of Mental Health, Bldg. 10, Rm. 4N-208, 10 Center Dr.-MSC 1255, Bethesda, MD 20892-1255, USA
Am J Psychiatry 162:1975-7. 2005..CONCLUSIONS: Children with bipolar disorder may have a reversal learning deficit... - Neurologic examination abnormalities in children with bipolar disorder or attention-deficit/hyperactivity disorderDaniel P Dickstein
National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 10 Center Drive MSC 1255, Building 10 Room 4N208, Bethesda MD 20892 1255, USA
Biol Psychiatry 58:517-24. 2005..To move beyond diagnosis toward unique pathophysiology, we evaluated both ADHD and BPD children for neurologic examination abnormalities (NEAs) in comparison with normal control (NC) children... - Using affect-modulated startle to study phenotypes of pediatric bipolar disorderBrendan A Rich
Pediatrics and Developmental Neuropsychiatry Branch, Department of Health and Human Services, National Institutes of Health, Bethesda, MD 20892, USA
Bipolar Disord 7:536-45. 2005..The current study used affect-modulated startle to examine potential differences in reactivity to emotional stimuli (reward and punishment) in narrow and broad phenotype PBD and controls... - Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in childrenMelissa A Brotman
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Biol Psychiatry 60:991-7. 2006..This syndrome has been called the "broad BD phenotype" or severe mood dysregulation (SMD). This study examines prevalence, concurrent Axis I diagnoses, and longitudinal outcome of SMD in an epidemiologic sample... - Cognitive flexibility in phenotypes of pediatric bipolar disorderDaniel P Dickstein
National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 9000 Rockville Pike, MSC 2670 Building 15K Room 204, Bethesda MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 46:341-55. 2007..6 +/- 2.4 years). Cognitive flexibility is relevant to symptoms of BD involving dysfunctional reward systems (e.g., excessive goal-directed activity and pleasure-seeking in mania; anhedonia in depression)... - Neuropsychological performance in pediatric bipolar disorderDaniel P Dickstein
National Institute of Mental Health Mood and Anxiety Disorders Program, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892-1255, USA
Biol Psychiatry 55:32-9. 2004..Our work suggests altered ventrolateral prefrontal cortex function, especially when linked to other lesion and neuroimaging studies... - Facial emotion labeling deficits in children and adolescents at risk for bipolar disorderMelissa A Brotman
Mood and Anxiety Disorders Program, NIMH, NIH, Bethesda, MD 20892, USA
Am J Psychiatry 165:385-9. 2008.... - Comorbid anxiety in phenotypes of pediatric bipolar disorderDaniel P Dickstein
Mood and Anxiety Disorders Program, Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892 1255, USA
J Child Adolesc Psychopharmacol 15:534-48. 2005..Adult BPD studies suggest comorbid anxiety disorders are common and impact treatment outcome. We explored the association of comorbid anxiety with two phenotypes of pediatric BPD... - Deficits in social cognition and response flexibility in pediatric bipolar disorderErin B McClure
Mood and Anxiety Disorders Program, NIMH, 15K North Dr, Room 102, MSC 2670, Bethesda, MD 20892, USA
Am J Psychiatry 162:1644-51. 2005..The purpose of this study was to test the hypothesis that youths with bipolar disorder would perform more poorly than matched healthy comparison subjects on measures of social cognition, motor inhibition, and response flexibility... - Memory and learning in pediatric bipolar disorderErin B McClure
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 44:461-9. 2005..To test the hypothesis that patients with pediatric bipolar disorder (PBPD) would demonstrate impairment relative to diagnosis-free controls of comparable age, gender, and IQ on measures of memory functioning... - Reward-related processes in pediatric bipolar disorder: a pilot studyMonique Ernst
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 15K North Drive, Room 118, Bethesda, MD 20892 2670, USA
J Affect Disord 82:S89-S101. 2004..We hypothesized that relative to healthy children, children with BPD would select risky options more frequently, be less confident in a favorable outcome, and report stronger emotional responses to outcomes...
Research Grants
- Bio-Behavioral Markers of Bipolar ConversionDANIEL DICKSTEIN; Fiscal Year: 2009..Such bio-behavioral markers of BD conversion could ultimately augment clinical history in a personalized medicine approach, resulting in improved (more specific or earlier) diagnosis and treatment. ..
- Bio-Behavioral Markers of Bipolar ConversionDaniel P Dickstein; Fiscal Year: 2010..Such bio-behavioral markers of BD conversion could ultimately augment clinical history in a personalized medicine approach, resulting in improved (more specific or earlier) diagnosis and treatment. ..