DANIEL DICKSTEIN

Summary

Affiliation: Brown University
Country: USA

Publications

  1. doi request reprint Developmental meta-analysis of the functional neural correlates of autism spectrum disorders
    Daniel P Dickstein
    Bradley Hospital s PediMIND Program, East Providence, RI 02915, USA
    J Am Acad Child Adolesc Psychiatry 52:279-289.e16. 2013
  2. doi request reprint Proton magnetic resonance spectroscopy in youth with severe mood dysregulation
    Daniel P Dickstein
    Unit on Bipolar Spectrum Disorders, Division of Intramural Research Programs, National Institute of Mental Health, Bethesda, MD, USA
    Psychiatry Res 163:30-9. 2008
  3. pmc Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation
    Daniel P Dickstein
    E P Bradley Hospital, Bradley Hasbro Children s Research Center, 1 Hoppin ST Coro West, Providence, RI 02903, USA
    J Child Adolesc Psychopharmacol 19:61-73. 2009
  4. doi request reprint Affect regulation in pediatric bipolar disorder
    Daniel P Dickstein
    Pediatric Mood, Imaging, and Neurodevelopment Program, EP Bradley Hospital, Bradley Hasbro Children s Research Center, Warren Alpert Medical School of Brown University, 1 Hoppin Street, Providence, RI 02903, USA
    Child Adolesc Psychiatr Clin N Am 18:405-20, ix. 2009
  5. pmc Impaired probabilistic reversal learning in youths with mood and anxiety disorders
    D P Dickstein
    National Institute of Mental Health NIMH Mood and Anxiety Disorders Program
    Psychol Med 40:1089-100. 2010
  6. pmc Fronto-temporal spontaneous resting state functional connectivity in pediatric bipolar disorder
    Daniel P Dickstein
    Bradley Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, USA
    Biol Psychiatry 68:839-46. 2010
  7. pmc Altered neural function in pediatric bipolar disorder during reversal learning
    Daniel P Dickstein
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
    Bipolar Disord 12:707-19. 2010
  8. doi request reprint Face processing in attention deficit/hyperactivity disorder
    Daniel P Dickstein
    PediMIND Program, E P Bradley Hospital, Alpert Medical School of Brown University, East Providence, USA
    Curr Top Behav Neurosci 9:219-37. 2012
  9. ncbi request reprint Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorder
    Ellen Leibenluft
    Emotion and Development Branch, Mood and Anxiety Disorders Program, NIMH, NIH, Health and Human Services, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
    Am J Psychiatry 164:52-60. 2007
  10. ncbi request reprint Brain systems underlying response flexibility in healthy and bipolar adolescents: an event-related fMRI study
    Eric E Nelson
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Building 106 C, 5413 W Cedar Lane, Bethesda, MD 20892, USA
    Bipolar Disord 9:810-9. 2007

Research Grants

  1. Bio-Behavioral Markers of Bipolar Conversion
    DANIEL DICKSTEIN; Fiscal Year: 2009
  2. Bio-Behavioral Markers of Bipolar Conversion
    Daniel P Dickstein; Fiscal Year: 2010

Detail Information

Publications27

  1. doi request reprint Developmental meta-analysis of the functional neural correlates of autism spectrum disorders
    Daniel P Dickstein
    Bradley Hospital s PediMIND Program, East Providence, RI 02915, USA
    J Am Acad Child Adolesc Psychiatry 52:279-289.e16. 2013
    ..We hypothesized that children and adolescents with ASD (<18 years old) would rely less on prefrontal cortex structures than adults (≥18 years old)...
  2. doi request reprint Proton magnetic resonance spectroscopy in youth with severe mood dysregulation
    Daniel P Dickstein
    Unit on Bipolar Spectrum Disorders, Division of Intramural Research Programs, National Institute of Mental Health, Bethesda, MD, USA
    Psychiatry Res 163:30-9. 2008
    ....
  3. pmc Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation
    Daniel P Dickstein
    E P Bradley Hospital, Bradley Hasbro Children s Research Center, 1 Hoppin ST Coro West, Providence, RI 02903, USA
    J Child Adolesc Psychopharmacol 19:61-73. 2009
    ..We conducted the first randomized double-blind, placebo-controlled trial in SMD youth, choosing lithium on the basis of its potential in treating irritability and aggression and neuro-metabolic effects...
  4. doi request reprint Affect regulation in pediatric bipolar disorder
    Daniel P Dickstein
    Pediatric Mood, Imaging, and Neurodevelopment Program, EP Bradley Hospital, Bradley Hasbro Children s Research Center, Warren Alpert Medical School of Brown University, 1 Hoppin Street, Providence, RI 02903, USA
    Child Adolesc Psychiatr Clin N Am 18:405-20, ix. 2009
    ..The present article reviews the current understanding of affect regulation. The authors also discuss recent findings implicating affect dysregulation in children and adolescents with bipolar disorder...
  5. pmc Impaired probabilistic reversal learning in youths with mood and anxiety disorders
    D P Dickstein
    National Institute of Mental Health NIMH Mood and Anxiety Disorders Program
    Psychol Med 40:1089-100. 2010
    ....
  6. pmc Fronto-temporal spontaneous resting state functional connectivity in pediatric bipolar disorder
    Daniel P Dickstein
    Bradley Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, USA
    Biol Psychiatry 68:839-46. 2010
    ..We now report the first use of task-independent spontaneous resting state functional connectivity (RSFC) to study the neural underpinnings of pediatric BD...
  7. pmc Altered neural function in pediatric bipolar disorder during reversal learning
    Daniel P Dickstein
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
    Bipolar Disord 12:707-19. 2010
    ..Here, we use event-related functional magnetic resonance imaging (fMRI) to elucidate neural correlates of reversal learning deficits in euthymic BD youth compared to typically developing controls...
  8. doi request reprint Face processing in attention deficit/hyperactivity disorder
    Daniel P Dickstein
    PediMIND Program, E P Bradley Hospital, Alpert Medical School of Brown University, East Providence, USA
    Curr Top Behav Neurosci 9:219-37. 2012
    ..Here, we review the neurobiology of face processing and suggest that face-processing alterations offer a window into the emotional dysfunction often accompanying ADHD...
  9. ncbi request reprint Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorder
    Ellen Leibenluft
    Emotion and Development Branch, Mood and Anxiety Disorders Program, NIMH, NIH, Health and Human Services, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
    Am J Psychiatry 164:52-60. 2007
    ..They also compared activation in medicated versus unmedicated children with bipolar disorder and in children with bipolar disorder and attention deficit hyperactivity disorder (ADHD) versus those with bipolar disorder without ADHD...
  10. ncbi request reprint Brain systems underlying response flexibility in healthy and bipolar adolescents: an event-related fMRI study
    Eric E Nelson
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Building 106 C, 5413 W Cedar Lane, Bethesda, MD 20892, USA
    Bipolar Disord 9:810-9. 2007
    ..The present study was undertaken to determine if neuronal responses differed between BD and control subjects on a simple motor response flexibility task...
  11. ncbi request reprint Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry study
    Daniel P Dickstein
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 62:734-41. 2005
    ..While numerous magnetic resonance imaging (MRI) studies have evaluated adults with bipolar disorder (BPD), few have examined MRI changes in children with BPD...
  12. pmc Neural connectivity in children with bipolar disorder: impairment in the face emotion processing circuit
    Brendan A Rich
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda 20892 2670, MD, USA
    J Child Psychol Psychiatry 49:88-96. 2008
    ....
  13. ncbi request reprint Emotion regulation in children and adolescents: boundaries between normalcy and bipolar disorder
    Daniel P Dickstein
    Mood and Anxiety Disorder Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
    Dev Psychopathol 18:1105-31. 2006
    ..Taken as a whole, this work implicates a neural circuit encompassing the prefrontal cortex, amygdala, and striatum in the pathophysiology of pediatric BD...
  14. pmc Neural activation during encoding of emotional faces in pediatric bipolar disorder
    Daniel P Dickstein
    Division of Intramural Research Program, National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, Bethesda, MD 20892 2670, USA
    Bipolar Disord 9:679-92. 2007
    ..To begin to address these limitations, the current study tests the hypothesis that pediatric BD (PBD) subjects exhibit altered neural activation during encoding of emotional faces compared to typically developing controls...
  15. ncbi request reprint Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulation
    Melissa A Brotman
    Emotion and Development Branch and the Genetic Basis of Mood and Anxiety Disorders Unit, Mood and Anxiety Disorders Program, NIMH, NIH, Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Psychiatry 164:1238-41. 2007
    ..The authors compared axis I diagnoses in parents of children with narrow phenotype bipolar disorder and parents of youth with severe mood dysregulation...
  16. ncbi request reprint Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disorders
    Melissa A Brotman
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Biol Psychiatry 61:819-21. 2007
    ..Although comorbid anxiety disorders are common in children with bipolar disorder (BD), it is unclear how this comorbidity impacts the pathophysiology of the illness...
  17. ncbi request reprint Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorder
    Tristan Gorrindo
    Mood and Anxiety Program, National Institute of Mental Health, Bldg 10, Rm 4N 208, 10 Center Dr MSC 1255, Bethesda, MD 20892 1255, USA
    Am J Psychiatry 162:1975-7. 2005
    ....
  18. ncbi request reprint Neurologic examination abnormalities in children with bipolar disorder or attention-deficit/hyperactivity disorder
    Daniel P Dickstein
    National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 10 Center Drive MSC 1255, Building 10 Room 4N208, Bethesda MD 20892 1255, USA
    Biol Psychiatry 58:517-24. 2005
    ..To move beyond diagnosis toward unique pathophysiology, we evaluated both ADHD and BPD children for neurologic examination abnormalities (NEAs) in comparison with normal control (NC) children...
  19. ncbi request reprint Using affect-modulated startle to study phenotypes of pediatric bipolar disorder
    Brendan A Rich
    Pediatrics and Developmental Neuropsychiatry Branch, Department of Health and Human Services, National Institutes of Health, Bethesda, MD 20892, USA
    Bipolar Disord 7:536-45. 2005
    ..The current study used affect-modulated startle to examine potential differences in reactivity to emotional stimuli (reward and punishment) in narrow and broad phenotype PBD and controls...
  20. ncbi request reprint Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children
    Melissa A Brotman
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Biol Psychiatry 60:991-7. 2006
    ..This syndrome has been called the "broad BD phenotype" or severe mood dysregulation (SMD). This study examines prevalence, concurrent Axis I diagnoses, and longitudinal outcome of SMD in an epidemiologic sample...
  21. ncbi request reprint Cognitive flexibility in phenotypes of pediatric bipolar disorder
    Daniel P Dickstein
    National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 9000 Rockville Pike, MSC 2670 Building 15K Room 204, Bethesda MD 20892 2670, USA
    J Am Acad Child Adolesc Psychiatry 46:341-55. 2007
    ..6 +/- 2.4 years). Cognitive flexibility is relevant to symptoms of BD involving dysfunctional reward systems (e.g., excessive goal-directed activity and pleasure-seeking in mania; anhedonia in depression)...
  22. ncbi request reprint Neuropsychological performance in pediatric bipolar disorder
    Daniel P Dickstein
    National Institute of Mental Health Mood and Anxiety Disorders Program, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1255, USA
    Biol Psychiatry 55:32-9. 2004
    ..We sought to examine whether neuropsychological function in children with bipolar disorder resembles that in adults with the illness and to extend our knowledge about cognitive function in pediatric bipolar disorder...
  23. doi request reprint Facial emotion labeling deficits in children and adolescents at risk for bipolar disorder
    Melissa A Brotman
    Mood and Anxiety Disorders Program, NIMH, NIH, Bethesda, MD 20892, USA
    Am J Psychiatry 165:385-9. 2008
    ....
  24. ncbi request reprint Comorbid anxiety in phenotypes of pediatric bipolar disorder
    Daniel P Dickstein
    Mood and Anxiety Disorders Program, Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892 1255, USA
    J Child Adolesc Psychopharmacol 15:534-48. 2005
    ..Adult BPD studies suggest comorbid anxiety disorders are common and impact treatment outcome. We explored the association of comorbid anxiety with two phenotypes of pediatric BPD...
  25. ncbi request reprint Deficits in social cognition and response flexibility in pediatric bipolar disorder
    Erin B McClure
    Mood and Anxiety Disorders Program, NIMH, 15K North Dr, Room 102, MSC 2670, Bethesda, MD 20892, USA
    Am J Psychiatry 162:1644-51. 2005
    ..The purpose of this study was to test the hypothesis that youths with bipolar disorder would perform more poorly than matched healthy comparison subjects on measures of social cognition, motor inhibition, and response flexibility...
  26. ncbi request reprint Memory and learning in pediatric bipolar disorder
    Erin B McClure
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
    J Am Acad Child Adolesc Psychiatry 44:461-9. 2005
    ..To test the hypothesis that patients with pediatric bipolar disorder (PBPD) would demonstrate impairment relative to diagnosis-free controls of comparable age, gender, and IQ on measures of memory functioning...
  27. ncbi request reprint Reward-related processes in pediatric bipolar disorder: a pilot study
    Monique Ernst
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 15K North Drive, Room 118, Bethesda, MD 20892 2670, USA
    J Affect Disord 82:S89-S101. 2004
    ..We hypothesized that relative to healthy children, children with BPD would select risky options more frequently, be less confident in a favorable outcome, and report stronger emotional responses to outcomes...

Research Grants3

  1. Bio-Behavioral Markers of Bipolar Conversion
    DANIEL DICKSTEIN; Fiscal Year: 2009
    ..Such bio-behavioral markers of BD conversion could ultimately augment clinical history in a personalized medicine approach, resulting in improved (more specific or earlier) diagnosis and treatment. ..
  2. Bio-Behavioral Markers of Bipolar Conversion
    Daniel P Dickstein; Fiscal Year: 2010
    ..Such bio-behavioral markers of BD conversion could ultimately augment clinical history in a personalized medicine approach, resulting in improved (more specific or earlier) diagnosis and treatment. ..