Jim Cypser

Summary

Affiliation: Brown University
Country: USA

Publications

  1. ncbi request reprint Meeting report--44th Annual Drosophila Research Conference
    Jim Cypser
    Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA
    Sci Aging Knowledge Environ 2003:PE12. 2003
  2. ncbi request reprint Hormesis in Caenorhabditis elegans dauer-defective mutants
    James R Cypser
    Institute for Behavioral Genetics, University of Colorado, Box 447, Boulder, CO 80309, USA
    Biogerontology 4:203-14. 2003
  3. ncbi request reprint Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity
    James R Cypser
    Institute for Behavioral Genetics, University of Colorado, Boulder 80303, USA
    J Gerontol A Biol Sci Med Sci 57:B109-14. 2002
  4. pmc A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
    Shane L Rea
    Institute for Behavioral Genetics, University of Colorado at Boulder, Box 447, Boulder, Colorado 80309, USA
    Nat Genet 37:894-8. 2005
  5. pmc Hormesis and aging in Caenorhabditis elegans
    James R Cypser
    University of Colorado, Institute for Behavioral Genetics, Box 447 Boulder, CO 80309, Fedex, 1480 30th St, Boulder, CO 80303, USA
    Exp Gerontol 41:935-9. 2006
  6. ncbi request reprint The U-shaped response of initial mortality in Caenorhabditis elegans to mild heat shock: does it explain recent trends in human mortality?
    Deqing Wu
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309, USA
    J Gerontol A Biol Sci Med Sci 63:660-8. 2008
  7. pmc Mortality shifts in Caenorhabditis elegans: remembrance of conditions past
    Deqing Wu
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309, USA
    Aging Cell 8:666-75. 2009
  8. ncbi request reprint Ginkgo biloba extract EGb 761 increases stress resistance and extends life span of Caenorhabditis elegans
    Zhixin Wu
    Department of Biological Sciences, The University of Southern Mississippi, Hattiesburg 39406, USA
    Cell Mol Biol (Noisy-le-grand) 48:725-31. 2002
  9. ncbi request reprint Insulin regulation of heart function in aging fruit flies
    Robert J Wessells
    The Burnham Institute, Center for Neuroscience and Aging, 10901 Torrey Pines Road, La Jolla, California 92037, USA
    Nat Genet 36:1275-81. 2004

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Meeting report--44th Annual Drosophila Research Conference
    Jim Cypser
    Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA
    Sci Aging Knowledge Environ 2003:PE12. 2003
    ..This Perspective provides an overview of research related to aging that was described at the annual Drosophila conference held in Chicago in March 2003...
  2. ncbi request reprint Hormesis in Caenorhabditis elegans dauer-defective mutants
    James R Cypser
    Institute for Behavioral Genetics, University of Colorado, Box 447, Boulder, CO 80309, USA
    Biogerontology 4:203-14. 2003
    ..Our results underscore the importance of the dauer-formation pathway in specifying life span by demonstrating a similar, but not identical, role in life extension attributed to hormesis...
  3. ncbi request reprint Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity
    James R Cypser
    Institute for Behavioral Genetics, University of Colorado, Boulder 80303, USA
    J Gerontol A Biol Sci Med Sci 57:B109-14. 2002
    ..In dose-response studies, induced thermotolerance paralleled the induced increase in life expectancy, which is consistent with a common origin...
  4. pmc A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
    Shane L Rea
    Institute for Behavioral Genetics, University of Colorado at Boulder, Box 447, Boulder, Colorado 80309, USA
    Nat Genet 37:894-8. 2005
    ....
  5. pmc Hormesis and aging in Caenorhabditis elegans
    James R Cypser
    University of Colorado, Institute for Behavioral Genetics, Box 447 Boulder, CO 80309, Fedex, 1480 30th St, Boulder, CO 80303, USA
    Exp Gerontol 41:935-9. 2006
    ..Mutations in three other genes of this pathway (daf-3, daf-5, and age-1) do not block induced life extension or induced thermotolerance; daf-5 mutants may be unusually sensitive to hormetic conditions...
  6. ncbi request reprint The U-shaped response of initial mortality in Caenorhabditis elegans to mild heat shock: does it explain recent trends in human mortality?
    Deqing Wu
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309, USA
    J Gerontol A Biol Sci Med Sci 63:660-8. 2008
    ..The dose of heat shock that coincided with this benefit in initial mortality did not affect the rate of increase in mortality...
  7. pmc Mortality shifts in Caenorhabditis elegans: remembrance of conditions past
    Deqing Wu
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309, USA
    Aging Cell 8:666-75. 2009
    ..However, 'b' (the rate of mortality increase with age) is always specified by the current conditions...
  8. ncbi request reprint Ginkgo biloba extract EGb 761 increases stress resistance and extends life span of Caenorhabditis elegans
    Zhixin Wu
    Department of Biological Sciences, The University of Southern Mississippi, Hattiesburg 39406, USA
    Cell Mol Biol (Noisy-le-grand) 48:725-31. 2002
    ..It appears that oxidative stress, a major determinant of life span, as well as other types of stress, can be successfully counteracted by the Ginlkgo biloba extract EGb 761...
  9. ncbi request reprint Insulin regulation of heart function in aging fruit flies
    Robert J Wessells
    The Burnham Institute, Center for Neuroscience and Aging, 10901 Torrey Pines Road, La Jolla, California 92037, USA
    Nat Genet 36:1275-81. 2004
    ..The aging fly heart is a model for studying the genetics of age-sensitive organ-specific pathology...