Linda Carpenter

Summary

Affiliation: Brown University
Country: USA

Publications

  1. doi Transcranial magnetic stimulation (TMS) for major depression: a multisite, naturalistic, observational study of acute treatment outcomes in clinical practice
    Linda L Carpenter
    Butler Hospital Brown Department of Psychiatry, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Depress Anxiety 29:587-96. 2012
  2. ncbi Service expectations and clinical characteristics of patients receiving psychiatric emergency services
    Linda L Carpenter
    Department of Psychiatry and Human Behavior, Brown Medical School in Providence, Rhode Island 02906, USA
    Psychiatr Serv 56:743-5. 2005
  3. ncbi A case series describing orlistat use in patients on psychotropic medications
    Linda L Carpenter
    Mood Disorders Program, Butler Hospital, Providence, RI 02906, USA
    Med Health R I 87:375-7. 2004
  4. pmc Effect of childhood physical abuse on cortisol stress response
    Linda L Carpenter
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Brown Department of Psychiatry and Human Behavior, Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA
    Psychopharmacology (Berl) 214:367-75. 2011
  5. ncbi Augmentation with open-label atomoxetine for partial or nonresponse to antidepressants
    Linda L Carpenter
    Mood Disorders Research Program, Butler Hospital, Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    J Clin Psychiatry 66:1234-8. 2005
  6. ncbi Open-label tiagabine monotherapy for major depressive disorder with anxiety
    Linda L Carpenter
    Mood Disorders Research Program, Butler Hospital, Brown Medical School, 345 Blackstone Boulevard, Providence, R I 02906, USA
    J Clin Psychiatry 67:66-71. 2006
  7. ncbi Neurostimulation in resistant depression
    Linda L Carpenter
    Department of Psychiatry, Brown University, Providence, RI 02906, USA
    J Psychopharmacol 20:35-40. 2006
  8. ncbi Vagus nerve stimulation and deep brain stimulation for treatment resistant depression
    Linda L Carpenter
    Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Med Health R I 89:137, 140-1. 2006
  9. pmc Dex/CRH test cortisol response in outpatients with major depression and matched healthy controls
    Linda L Carpenter
    Department of Psychiatry and Human Behavior, Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Brown Medical School, Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA
    Psychoneuroendocrinology 34:1208-13. 2009
  10. pmc Effect of childhood emotional abuse and age on cortisol responsivity in adulthood
    Linda L Carpenter
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, Brown Department of Psychiatry and Human Behavior, Providence, Rhode Island 02906, USA
    Biol Psychiatry 66:69-75. 2009

Research Grants

Detail Information

Publications57

  1. doi Transcranial magnetic stimulation (TMS) for major depression: a multisite, naturalistic, observational study of acute treatment outcomes in clinical practice
    Linda L Carpenter
    Butler Hospital Brown Department of Psychiatry, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Depress Anxiety 29:587-96. 2012
    ..Few studies have examined the effectiveness of transcranial magnetic stimulation (TMS) in real-world clinical practice settings...
  2. ncbi Service expectations and clinical characteristics of patients receiving psychiatric emergency services
    Linda L Carpenter
    Department of Psychiatry and Human Behavior, Brown Medical School in Providence, Rhode Island 02906, USA
    Psychiatr Serv 56:743-5. 2005
    ..These findings suggest the importance of efforts to educate the public about how to obtain mental health services...
  3. ncbi A case series describing orlistat use in patients on psychotropic medications
    Linda L Carpenter
    Mood Disorders Program, Butler Hospital, Providence, RI 02906, USA
    Med Health R I 87:375-7. 2004
  4. pmc Effect of childhood physical abuse on cortisol stress response
    Linda L Carpenter
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Brown Department of Psychiatry and Human Behavior, Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA
    Psychopharmacology (Berl) 214:367-75. 2011
    ..However, studies of childhood maltreatment and adult HPA function have not yet rigorously investigated the differential effects of maltreatment subtypes, including physical abuse...
  5. ncbi Augmentation with open-label atomoxetine for partial or nonresponse to antidepressants
    Linda L Carpenter
    Mood Disorders Research Program, Butler Hospital, Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    J Clin Psychiatry 66:1234-8. 2005
    ..Other compounds that enhance synaptic norepinephrine have shown efficacy as antidepressant monotherapies and as augmentation agents. This case series study examined the role of atomoxetine in antidepressant augmentation...
  6. ncbi Open-label tiagabine monotherapy for major depressive disorder with anxiety
    Linda L Carpenter
    Mood Disorders Research Program, Butler Hospital, Brown Medical School, 345 Blackstone Boulevard, Providence, R I 02906, USA
    J Clin Psychiatry 67:66-71. 2006
    ..Tiagabine, a selective GABA reuptake inhibitor (SGRI) that enhances normal GABA tone, was evaluated for its efficacy and safety in the treatment of depression comorbid with significant anxiety...
  7. ncbi Neurostimulation in resistant depression
    Linda L Carpenter
    Department of Psychiatry, Brown University, Providence, RI 02906, USA
    J Psychopharmacol 20:35-40. 2006
    ..Further development and evaluation of non-pharmacological antidepressant therapies are needed, with the hope of improving treatment of refactory depression...
  8. ncbi Vagus nerve stimulation and deep brain stimulation for treatment resistant depression
    Linda L Carpenter
    Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Med Health R I 89:137, 140-1. 2006
    ..Further investigations are currently underway in order to more fully evaluate both of these neurostimulation therapies, with the hope of substantially improving the treatment of refractory depression...
  9. pmc Dex/CRH test cortisol response in outpatients with major depression and matched healthy controls
    Linda L Carpenter
    Department of Psychiatry and Human Behavior, Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Brown Medical School, Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA
    Psychoneuroendocrinology 34:1208-13. 2009
    ..A diminished hormone response has been observed in chronically depressed outpatients...
  10. pmc Effect of childhood emotional abuse and age on cortisol responsivity in adulthood
    Linda L Carpenter
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, Brown Department of Psychiatry and Human Behavior, Providence, Rhode Island 02906, USA
    Biol Psychiatry 66:69-75. 2009
    ..Several studies have shown abnormal cortisol reactivity in phenotypically healthy adults without psychiatric disorders as a function of exposure to adverse early environments...
  11. pmc Association between plasma IL-6 response to acute stress and early-life adversity in healthy adults
    Linda L Carpenter
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, Providence, RI 02906, USA
    Neuropsychopharmacology 35:2617-23. 2010
    ..Inflammation may be an important developmental mediator linking adverse experiences in early life to poor adult physical and mental health. The results of this preliminary study warrant further investigation in a larger sample...
  12. doi A placebo-controlled study of sertraline's effect on cortisol response to the dexamethasone/corticotropin-releasing hormone test in healthy adults
    Linda L Carpenter
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Brown Department of Psychiatry and Human Behavior, Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA
    Psychopharmacology (Berl) 218:371-9. 2011
    ..These findings prompted research into the use of the Dex/CRH test as a tool for developing antidepressant drugs...
  13. ncbi Acute changes in cerebrospinal fluid 5-HIAA following oral paroxetine challenge in healthy humans
    Linda L Carpenter
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA
    Neuropsychopharmacology 28:339-47. 2003
    ..Our findings stand in contrast to the decreases reported for CSF 5-HIAA after chronic SSRI treatment in humans and the decreases seen in brain extracellular 5-HIAA after acute or chronic administration of SSRIs to animals...
  14. ncbi Cerebrospinal fluid interleukin (IL)-6 in unipolar major depression
    Linda L Carpenter
    Mood Disorders Research Program, Butler Hospital, and Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI, USA
    J Affect Disord 79:285-9. 2004
    ..This study was undertaken to determine whether IL-6 concentrations in cerebrospinal fluid (CSF) differ between depressed patients and healthy control subjects...
  15. ncbi Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed patients and healthy control subjects
    Linda L Carpenter
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, Providence, RI 02906, USA
    Neuropsychopharmacology 29:777-84. 2004
    ..More work is needed to elucidate the critical nature and timing of early events that may be associated with enduring neuroendocrine changes in humans...
  16. ncbi Do obese depressed patients respond to topiramate? A retrospective chart review
    Linda L Carpenter
    Mood Disorders Program, Butler Hospital and Department of Psychiatry and Human Behavior, Brown University School of Medicine, 345 Blackstone Blvd, Providence, RI 02906, USA
    J Affect Disord 69:251-5. 2002
    ..Topiramate's tendency to cause weight loss could be advantageous for many patients with mood disorders...
  17. ncbi Cerebrospinal fluid interleukin-6 in obsessive-compulsive disorder and trichotillomania
    Linda L Carpenter
    Mood Disorders Research Program, Butler Hospital, and Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Psychiatry Res 112:257-62. 2002
    ..3+/-0.8 pg/ml) and their matched controls (n=14) (1.9+/-0.5 pg/ml). These findings fail to support speculation that ongoing immune activation may be causally involved in the pathogenesis of OCD or trichotillomania...
  18. ncbi Cervical vagus nerve stimulation for treatment-resistant depression
    Linda L Carpenter
    Department of Psychiatry, Brown University Medical School, Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Neurosurg Clin N Am 14:275-82. 2003
    ..Longer term data on VNS in depressed patients as well as further information regarding the possible dose-response relation will help to determine the place of VNS in the armament of therapeutic modalities available for major depression...
  19. ncbi A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression
    Mark S George
    Department of Psychiatry, Medical University of South Carolina, 67 President Street 502 N, Charleston, SC 29425, USA
    Biol Psychiatry 58:364-73. 2005
    ..To better understand these effects on long-term outcome, we compared 12-month VNS+TAU outcomes with those of a comparable TRD group...
  20. ncbi Sex differences in emotional and physiological responses to the Trier Social Stress Test
    Megan M Kelly
    Mood Disorders Research Program, Department of Psychiatry and Human Behavior, Butler Hospital, Brown Medical School, 345 Blackstone Blvd, Providence, RI 02906, USA
    J Behav Ther Exp Psychiatry 39:87-98. 2008
    ..The broader implications of these results and how they relate to sex differences in the etiology and clinical presentation of anxiety and mood disorders are discussed...
  21. ncbi Varenicline augmentation in depressed smokers: an 8-week, open-label study
    Noah S Philip
    Mood Disorders Research Program, Butler Hospital, and the Department of Psychiatry and Human Behavior, The Warren Alpert Medical School at Brown University, Providence, R I, USA
    J Clin Psychiatry 70:1026-31. 2009
    ..To assess possible antidepressant effects of varenicline augmentation in outpatients with treatment-resistant depressive disorders and nicotine dependence...
  22. ncbi Effect of vagus nerve stimulation on cerebrospinal fluid monoamine metabolites, norepinephrine, and gamma-aminobutyric acid concentrations in depressed patients
    Linda L Carpenter
    Laboratory for Clinical Neuroscience, Butler Hospital, Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, Rhode Island 02906, USA edu
    Biol Psychiatry 56:418-26. 2004
    ..Cerebrospinal fluid (CSF) studies in epilepsy patients show that VNS alters concentrations of monamines and gamma-aminobutyric acid (GABA), neurotransmitter systems possibly involved in the pathogenesis of depression...
  23. ncbi Interplay between childhood maltreatment, parental bonding, and gender effects: impact on quality of life
    Kobita Rikhye
    Mood Disorders Research Program, Butler Hospital, Department of Psychiatry and Human Behavior, Brown Medical School, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Child Abuse Negl 32:19-34. 2008
    ..The aim of this study was to examine associations between childhood adversity, parental bonding, gender, depressive symptoms, and quality of life in non-treatment-seeking adults from the community...
  24. ncbi Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Biol Psychiatry 58:355-63. 2005
    ..The need for effective, long-term treatment for recurrent or chronic, treatment-resistant depression is well established...
  25. ncbi Update on stress and depression: the role of the hypothalamic-pituitary-adrenal (HPA) axis
    Andrea de Abreu Feijó de Mello
    Butler Hospital, Department of Psychiatry and Human Behavior, Brown Medical School, Rhode Island, USA
    Rev Bras Psiquiatr 25:231-8. 2003
    ....
  26. ncbi Sex differences in the use of coping strategies: predictors of anxiety and depressive symptoms
    Megan M Kelly
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, Providence, Rhode Island
    Depress Anxiety 25:839-46. 2008
    ..The observed sex differences in the use of coping strategies and their association with depression and anxiety-related problems underscores differences in the clinical presentation of anxiety and depression between women and men...
  27. pmc Childhood parental loss and adult hypothalamic-pituitary-adrenal function
    Audrey R Tyrka
    Mood Disorders Research Program, Laboratory for Clinical Neuroscience, Butler Hospital, Providence, Rhode Island 02906, USA
    Biol Psychiatry 63:1147-54. 2008
    ....
  28. ncbi The evolution of deep brain stimulation for neuropsychiatric disorders
    Benjamin D Greenberg
    Department of Psychiatry and Human Behavior, Warren Alpert Medical School at Brown University, Butler Hospital, Providence, RI 02906, USA
    Front Biosci 13:4638-48. 2008
    ..Further development of DBS for these and other illnesses with primarily behavioral symptoms will require thoughtful collaboration among multiple disciplines...
  29. pmc The role of negative affect in risk for early lapse among low distress tolerance smokers
    Ana M Abrantes
    Butler Hospital Alpert Medical School of Brown University, 345 Blackstone Blvd, Providence, RI 02906, USA
    Addict Behav 33:1394-401. 2008
    ....
  30. pmc Childhood parental loss and adult psychopathology: effects of loss characteristics and contextual factors
    Audrey R Tyrka
    Butler Hospital, Providence, RI 02906, USA
    Int J Psychiatry Med 38:329-44. 2008
    ..For parental separation/desertion, our results highlight the overriding influence of risk factors that commonly co-occur with this form of parental loss...
  31. pmc Childhood maltreatment and adult personality disorder symptoms: influence of maltreatment type
    Audrey R Tyrka
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, Providence, RI 02906, USA
    Psychiatry Res 165:281-7. 2009
    ..There were no significant differences between the maltreatment groups. These findings indicate that emotional abuse/neglect and physical/sexual abuse are risk factors for a broad array of personality outcomes in a non-clinical sample...
  32. pmc A prospective examination of distress tolerance and early smoking lapse in adult self-quitters
    Richard A Brown
    Warren Alpert Medical School of Brown University, Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Nicotine Tob Res 11:493-502. 2009
    ..How one reacts to the discomfort of nicotine withdrawal and quitting smoking (i.e., distress tolerance) may be a more promising avenue of investigation with important treatment implications...
  33. pmc Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity
    Audrey R Tyrka
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, Providence, Rhode Island 02906, USA
    Biol Psychiatry 66:681-5. 2009
    ..This study was conducted to determine whether CRHR1 polymorphisms interact with childhood maltreatment to predict hypothalamic-pituitary-adrenal (HPA) axis reactivity, which has been linked to both depression and early life stress...
  34. doi Nicotinic acetylcholine receptors and depression: a review of the preclinical and clinical literature
    Noah S Philip
    Butler Hospital, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI 02906, USA
    Psychopharmacology (Berl) 212:1-12. 2010
    ..Taken together, the preclinical and clinical evidence suggests that drugs targeting nAChRs may represent an important new approach to the treatment of depression...
  35. pmc Gene-environment interactions: early life stress and risk for depressive and anxiety disorders
    Nicole R Nugent
    Bradley Hasbro Children s Research Center, Rhode Island Hospital, Coro West Building, One Hoppin Street, Suite 204, Providence, RI 02903, USA
    Psychopharmacology (Berl) 214:175-96. 2011
    ..e., depressive and anxiety) disorders. Recent findings have suggested a unique role for early life stress (ELS) in the development of internalizing disorders, contributing to the rapid proliferation of research in this area...
  36. pmc Cortisol and ACTH responses to the Dex/CRH test: influence of temperament
    Audrey R Tyrka
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Horm Behav 53:518-25. 2008
    ..Increased adrenocortical reactivity, which previously has been linked to major depression and anxiety disorders, may contribute to the association between temperament/personality traits and these disorders...
  37. ncbi Biomarkers in the human stress system: do they signal risk for depression?
    Audrey R Tyrka
    Department of Psychiatry and Human Behavior, Brown Medical School, USA
    Med Health R I 89:180-2. 2006
  38. ncbi Increased cerebrospinal fluid corticotropin-releasing factor concentrations during tryptophan depletion in healthy adults
    Audrey R Tyrka
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island, USA
    Biol Psychiatry 56:531-4. 2004
    ..This study examined the effect of tryptophan depletion, which acutely reduces brain serotonin concentrations, on serial cerebrospinal fluid concentrations of corticotropin-releasing factor in healthy humans...
  39. ncbi Decreased cerebrospinal fluid concentrations of substance P in treatment-resistant depression and lack of alteration after acute adjunct vagus nerve stimulation therapy
    Linda L Carpenter
    Mood Disorders Research Program, Butler Hospital, Brown University, Providence, RI, USA
    Psychiatry Res 157:123-9. 2008
    ..Low CSF SP may reflect a biological marker of the subtype of severe and chronic depression that is resistant to standard therapies...
  40. ncbi Psychotic major depression: a benefit-risk assessment of treatment options
    Audrey R Tyrka
    Mood Disorders Research Program, and the Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, Rhode Island 02906, USA
    Drug Saf 29:491-508. 2006
    ..Problems with this literature are highlighted, and strategies for future research are suggested...
  41. pmc Decreased adrenocorticotropic hormone and cortisol responses to stress in healthy adults reporting significant childhood maltreatment
    Linda L Carpenter
    Mood Disorders Research Program, Butler Hospital, Brown Medical School, Providence, Rhode Island 02906, USA
    Biol Psychiatry 62:1080-7. 2007
    ..Abnormal HPA response to stress challenge has been reported in adult patients with major depressive disorder and posttraumatic stress disorder...
  42. pmc Childhood maltreatment and telomere shortening: preliminary support for an effect of early stress on cellular aging
    Audrey R Tyrka
    Mood Disorders Research Program, Butler Hospital, Providence, Rhode Island, USA
    Biol Psychiatry 67:531-4. 2010
    ..Based on previous evidence linking psychosocial stress to shorter telomere length, this study was designed to evaluate the effect of childhood adversity on telomere length...
  43. ncbi Temperament and hypothalamic-pituitary-adrenal axis function in healthy adults
    Audrey R Tyrka
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, 345 Blackstone Road, Providence, RI 02906, USA
    Psychoneuroendocrinology 31:1036-45. 2006
    ..A recent study found HPA hyperactivity in adults with high levels of neuroticism. The present study investigated associations of temperament and HPA function in 31 healthy adults...
  44. ncbi Genotype-controlled analysis of plasma dopamine beta-hydroxylase activity in psychotic unipolar major depression
    Joseph F Cubells
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 51:358-64. 2002
    ..Plasma DbetaH is under genetic control by the structural locus encoding DbetaH protein, DBH. This study tested the hypothesis that diagnosis-specific allelic variation at DBH accounts for lower plasma DbetaH in UDPF...
  45. pmc Pharmacologic approaches to treatment resistant depression: a re-examination for the modern era
    Noah S Philip
    Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Butler Hospital, Providence, RI 02906, USA
    Expert Opin Pharmacother 11:709-22. 2010
    ..The review ends by considering drugs acting on the melatonin, acetylcholine, and glutamate systems that hold promise as future options for TRD...
  46. doi Patterns of quetiapine use in psychiatric inpatients: an examination of off-label use
    Noah S Philip
    Butler Hospital and Department of Psychiatry and Human Behavior, The Warren Alpert Medical School at Brown University, Providence, RI 02906, USA
    Ann Clin Psychiatry 20:15-20. 2008
    ..To investigate such usage of quetiapine, we evaluated prescribing practices of this drug at our acute-care psychiatric hospital...
  47. ncbi A double-blind, placebo-controlled study of antidepressant augmentation with mirtazapine
    Linda L Carpenter
    Mood Disorders Program, Butler Hospital, and Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, Rhode Island 02906, USA
    Biol Psychiatry 51:183-8. 2002
    ..A double-blind controlled trial was undertaken to further elucidate the efficacy of this intervention...
  48. doi Augmentation of antidepressants with atypical antipsychotics: a review of the current literature
    Noah S Philip
    Mood Disorders Research Program, Butler Hospital, Providence, RI 02906, USA
    J Psychiatr Pract 14:34-44. 2008
    ....
  49. ncbi Synergistic action of 5-HT2A antagonists and selective serotonin reuptake inhibitors in neuropsychiatric disorders
    Gerard J Marek
    Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA
    Neuropsychopharmacology 28:402-12. 2003
    ....
  50. ncbi Neurosurgery for intractable obsessive-compulsive disorder and depression: critical issues
    Benjamin D Greenberg
    Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Neurosurg Clin N Am 14:199-212. 2003
    ....
  51. ncbi Surgical aspects of deep brain stimulation
    Gerhard M Friehs
    Clinical Neurosciences Neurosurgery, Brown Medical School, USA
    Med Health R I 89:134-6. 2006
  52. ncbi The relationship between childhood abuse and adult personality disorder symptoms
    Kelly E Grover
    Mood Disorders Research Program and Laboratory for Clinical Neuroscience, Butler Hospital, Providence, RI 02906, USA
    J Pers Disord 21:442-7. 2007
    ..These findings link reports of childhood abuse with symptoms of personality disorders in the absence of Axis I psychiatric disorders in a community sample of healthy adults...
  53. pmc A sequencing-based survey of functional APAF1 alleles in a large sample of individuals with affective illness and population controls
    Zenab Amin
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med Genet B Neuropsychiatr Genet 153:332-5. 2010
    ..In addition, the E777K and N782T variants were found at low frequencies both in patients and population controls, suggesting that these variants have limited impact on risk for MDD...
  54. ncbi Elevated cerebrospinal fluid substance p concentrations in posttraumatic stress disorder and major depression
    Thomas D Geracioti
    Research Service, VA Medical Center, 3200 Vine St, Box 151, Cincinnati, OH 45220, USA
    Am J Psychiatry 163:637-43. 2006
    ..The authors also sought to determine if CNS substance P concentrations change on provocation of symptoms in PTSD patients...
  55. ncbi [Depression and stress: is there an endophenotype?]
    Andrea Feijo Mello
    Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil, and Programa de Pesquisas em Transtornos do Humor, Hospital Butler, USA
    Rev Bras Psiquiatr 29:S13-8. 2007
    ..To review the new findings about stress, hypothalamic-pituitary-adrenal axis and depression trying to explain a possible endophenotype prone to depression...
  56. ncbi Mifepristone versus placebo in the treatment of psychosis in patients with psychotic major depression
    Charles DeBattista
    Corcept Therapeutics, Menlo Park, California, USA
    Biol Psychiatry 60:1343-9. 2006
    ..Recent studies have suggested that the antiglucocorticoid, mifepristone might have a role in the treatment of PMD. The current study tested the efficacy of mifepristone treatment of the psychotic symptoms of PMD...
  57. ncbi Levetiracetam-induced depression in a healthy adult
    Lauren M Wier
    J Clin Psychiatry 67:1159-60. 2006

Research Grants6

  1. DEX/CRH Response: Mood/Anxiety Disorder Endophenotype?
    Linda Carpenter; Fiscal Year: 2007
    ....
  2. DEX/CRH Response: Mood/Anxiety Disorder Endophenotype?
    Linda Carpenter; Fiscal Year: 2009
    ....
  3. DEX/CRH Response: Mood/Anxiety Disorder Endophenotype?
    Linda Carpenter; Fiscal Year: 2010
    ....