DAVID BERSON

Summary

Affiliation: Brown University
Country: USA

Publications

  1. pmc Mouse ganglion-cell photoreceptors are driven by the most sensitive rod pathway and by both types of cones
    Shijun Weng
    Department of Neuroscience, Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 8:e66480. 2013
  2. ncbi The zeta cell: a new ganglion cell type in cat retina
    D M Berson
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    J Comp Neurol 399:269-88. 1998
  3. ncbi Phototransduction in ganglion-cell photoreceptors
    David M Berson
    Department of Neuroscience, Brown University, P O Box G L4, Providence, RI 02912, USA
    Pflugers Arch 454:849-55. 2007
  4. ncbi Strange vision: ganglion cells as circadian photoreceptors
    David M Berson
    Department of Neuroscience, Brown University, Providence, RI 02912, USA
    Trends Neurosci 26:314-20. 2003
  5. ncbi Phototransduction by retinal ganglion cells that set the circadian clock
    David M Berson
    Department of Neuroscience, Brown University, Providence, RI, 02912 USA
    Science 295:1070-3. 2002
  6. ncbi The Eta ganglion cell type of cat retina
    D M Berson
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    J Comp Neurol 408:204-19. 1999
  7. ncbi Inhibitory network properties shaping the light evoked responses of cat alpha retinal ganglion cells
    Brendan J O'Brien
    Department of Neuroscience, Brown University, Box 1953, Providence, RI 02912 1953, USA
    Vis Neurosci 20:351-61. 2003
  8. pmc Ectopic retinal ON bipolar cell synapses in the OFF inner plexiform layer: contacts with dopaminergic amacrine cells and melanopsin ganglion cells
    Olivia N Dumitrescu
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912
    J Comp Neurol 517:226-44. 2009
  9. pmc Synaptic influences on rat ganglion-cell photoreceptors
    Kwoon Y Wong
    Department of Neuroscience, Brown University, Box G L471, Providence, RI 02912, USA
    J Physiol 582:279-96. 2007
  10. ncbi The retina-attached SCN slice preparation: an in vitro mammalian circadian visual system
    Kwoon Y Wong
    Department of Neuroscience, Brown University, Providence, RI 02912, USA
    J Biol Rhythms 22:400-10. 2007

Research Grants

  1. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2000
  2. Biology of Photosensitive Ganglion Cells
    David M Berson; Fiscal Year: 2010
  3. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2009
  4. Biology of Photosensitive Ganglion Cells
    DAVID BERSON; Fiscal Year: 2009
  5. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2007
  6. Biology of Photosensitive Ganglion Cells
    DAVID BERSON; Fiscal Year: 2007
  7. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2006
  8. Biology of Photosensitive Ganglion Cells
    DAVID BERSON; Fiscal Year: 2006
  9. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2005
  10. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2004

Collaborators

Detail Information

Publications22

  1. pmc Mouse ganglion-cell photoreceptors are driven by the most sensitive rod pathway and by both types of cones
    Shijun Weng
    Department of Neuroscience, Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 8:e66480. 2013
    ..These synaptic inputs greatly expand the dynamic range and spectral bandpass of the non-image-forming visual functions for which ipRGCs provide the principal retinal input...
  2. ncbi The zeta cell: a new ganglion cell type in cat retina
    D M Berson
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    J Comp Neurol 399:269-88. 1998
    ..Strong commonalities with similar ganglion cell types in ferret, rabbit, and monkey suggest that "zeta-like" cells may be a universal feature of the mammalian retina...
  3. ncbi Phototransduction in ganglion-cell photoreceptors
    David M Berson
    Department of Neuroscience, Brown University, P O Box G L4, Providence, RI 02912, USA
    Pflugers Arch 454:849-55. 2007
    ....
  4. ncbi Strange vision: ganglion cells as circadian photoreceptors
    David M Berson
    Department of Neuroscience, Brown University, Providence, RI 02912, USA
    Trends Neurosci 26:314-20. 2003
    ..They also contribute to the pupillary light reflex and other behavioral and physiological responses to environmental illumination...
  5. ncbi Phototransduction by retinal ganglion cells that set the circadian clock
    David M Berson
    Department of Neuroscience, Brown University, Providence, RI, 02912 USA
    Science 295:1070-3. 2002
    ..The sensitivity, spectral tuning, and slow kinetics of this light response matched those of the photic entrainment mechanism, suggesting that these ganglion cells may be the primary photoreceptors for this system...
  6. ncbi The Eta ganglion cell type of cat retina
    D M Berson
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    J Comp Neurol 408:204-19. 1999
    ..The morphology and projection patterns of the eta cell suggest that its physiologic counterpart is a type of sluggish or W-cell with an OFF center, an ON surround, and possibly a transient light response...
  7. ncbi Inhibitory network properties shaping the light evoked responses of cat alpha retinal ganglion cells
    Brendan J O'Brien
    Department of Neuroscience, Brown University, Box 1953, Providence, RI 02912 1953, USA
    Vis Neurosci 20:351-61. 2003
    ..This circuitry may moderate nonlinearities in the alpha-cell light response and could account for some excitatory and inhibitory influences on alpha cells known to arise from outside the classical receptive field...
  8. pmc Ectopic retinal ON bipolar cell synapses in the OFF inner plexiform layer: contacts with dopaminergic amacrine cells and melanopsin ganglion cells
    Olivia N Dumitrescu
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912
    J Comp Neurol 517:226-44. 2009
    ..Imaging studies in dissociated bipolar cells show that these ectopic ribbon synapses are capable of vesicular release. There is thus an accessory ON sublayer in the outer IPL...
  9. pmc Synaptic influences on rat ganglion-cell photoreceptors
    Kwoon Y Wong
    Department of Neuroscience, Brown University, Box G L471, Providence, RI 02912, USA
    J Physiol 582:279-96. 2007
    ..These extrinsic ipRGC light responses can explain some of the previously reported properties of circadian photoentrainment and other non-image-forming visual behaviours...
  10. ncbi The retina-attached SCN slice preparation: an in vitro mammalian circadian visual system
    Kwoon Y Wong
    Department of Neuroscience, Brown University, Providence, RI 02912, USA
    J Biol Rhythms 22:400-10. 2007
    ..The authors have also been able to generate this preparation from mice, demonstrating the feasibility of applying this method to transgenic mice...
  11. pmc Central projections of melanopsin-expressing retinal ganglion cells in the mouse
    Samer Hattar
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2105, USA
    J Comp Neurol 497:326-49. 2006
    ..Staining patterns after monocular enucleation revealed that the projections of these cells are overwhelmingly crossed except for the projection to the SCN, which is bilaterally symmetrical...
  12. ncbi Photoreceptor adaptation in intrinsically photosensitive retinal ganglion cells
    Kwoon Y Wong
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    Neuron 48:1001-10. 2005
    ..Implications for the mechanisms generating various non-image-forming visual responses are discussed...
  13. pmc Hyperpolarization-activated current (I(h)) in ganglion-cell photoreceptors
    Matthew J Van Hook
    Department of Neuroscience, Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 5:e15344. 2010
    ..This study is the first to characterize I(h) in a well-defined population of retinal ganglion cells, namely SCN-projecting ipRGCs...
  14. pmc Circadian modulation of melanopsin-driven light response in rat ganglion-cell photoreceptors
    Shijun Weng
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    J Biol Rhythms 24:391-402. 2009
    ..However, this gain change is probably too modest to contribute much to shape the phase response curve (PRC) for behavioral photoentrainment...
  15. pmc Intrinsic physiological properties of cat retinal ganglion cells
    Brendan J O'Brien
    Department of Neuroscience, Box 1953, Brown University, Providence, RI 02912 1953, USA
    J Physiol 538:787-802. 2002
    ..Such differences are certain to affect how each type responds to synaptic input and may help tune each cell type appropriately for their individual roles in visual processing...
  16. pmc Morphology and mosaics of melanopsin-expressing retinal ganglion cell types in mice
    David M Berson
    Department of Neuroscience, Brown University, Providence, Rhode Island, USA
    J Comp Neurol 518:2405-22. 2010
    ..Finally, we observed weak melanopsin immunoreactivity in other ganglion cells, mostly with large somata, that may constitute one or more additional types of melanopsin-expressing cells...
  17. pmc Morphology of retinal ganglion cells in the ferret (Mustela putorius furo)
    Tomoki Isayama
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    J Comp Neurol 517:459-80. 2009
    ..Our data indicate that, among carnivore species, the retinal ganglion cells resemble one another closely and that the ferret is a useful model for studies of the ontogenetic differentiation of ganglion cell types...
  18. doi Melanopsin ganglion cells use a membrane-associated rhabdomeric phototransduction cascade
    Dustin M Graham
    Department of Neuroscience, Brown University, Providence, RI 02912, USA
    J Neurophysiol 99:2522-32. 2008
    ..The striking similarity of phototransduction in ipRGCs and invertebrate rhabdomeric photoreceptors reinforces the emerging view that these cells have a common evolutionary origin...
  19. ncbi Induction of photosensitivity by heterologous expression of melanopsin
    Xudong Qiu
    Department of Neuroscience, Box 1953, Brown University, Providence, Rhode Island 02912 1953, USA
    Nature 433:745-9. 2005
    ..We conclude that mammalian melanopsin is a functional sensory photopigment, that it is the photopigment of ganglion-cell photoreceptors, and that these photoreceptors may use an invertebrate-like phototransduction cascade...
  20. pmc Intraretinal signaling by ganglion cell photoreceptors to dopaminergic amacrine neurons
    Dao Qi Zhang
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Proc Natl Acad Sci U S A 105:14181-6. 2008
    ..This unprecedented centrifugal outflow of ganglion-cell signals within the retina provides a novel basis for the restructuring of retinal circuits by light...
  21. pmc Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision
    Ali D Guler
    Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Nature 453:102-5. 2008
    ..These results indicate that light signals for irradiance detection are dissociated from pattern vision at the retinal ganglion cell level, and animals that cannot detect light for NIF functions are still capable of image formation...
  22. ncbi Melanopsin, ganglion-cell photoreceptors, and mammalian photoentrainment
    Mark D Rollag
    Department of Anatomy Physiology and Genetics, Uniformed Services University, Bethesda, MD 20814, USA
    J Biol Rhythms 18:227-34. 2003
    ..This review summarizes recent findings related to melanopsin and melanopsin ganglion cells and lists other retinal proteins that might serve as photopigments in the mammalian photoentrainment input pathway...

Research Grants16

  1. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2000
    ..The study will expand our understanding of how diverse GC types implement the range of transformations of the retinal image carried out by the mammalian retina. ..
  2. Biology of Photosensitive Ganglion Cells
    David M Berson; Fiscal Year: 2010
    ..abstract_text> ..
  3. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2009
    ..They also bear on fundamental mechanisms of circadian and adaptation modulation of retinal function. ..
  4. Biology of Photosensitive Ganglion Cells
    DAVID BERSON; Fiscal Year: 2009
    ..abstract_text> ..
  5. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2007
    ..abstract_text> ..
  6. Biology of Photosensitive Ganglion Cells
    DAVID BERSON; Fiscal Year: 2007
    ....
  7. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2006
    ..abstract_text> ..
  8. Biology of Photosensitive Ganglion Cells
    DAVID BERSON; Fiscal Year: 2006
    ....
  9. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2005
    ..abstract_text> ..
  10. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2004
    ..abstract_text> ..
  11. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2003
    ..abstract_text> ..
  12. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2002
    ..The study will expand our understanding of how diverse GC types implement the range of transformations of the retinal image carried out by the mammalian retina. ..
  13. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    DAVID BERSON; Fiscal Year: 2001
    ..The study will expand our understanding of how diverse GC types implement the range of transformations of the retinal image carried out by the mammalian retina. ..
  14. STRUCTURE AND FUNCTION OF MAMMALIAN GANGLION CELLS
    David M Berson; Fiscal Year: 2010
    ..They also bear on fundamental mechanisms of circadian and adaptation modulation of retinal function. ..