M S Bauer

..They review the literature on the efficacy of agents in any of these four roles to determine which if any agents meet this definition of mood stabilizer...

..Treatment nonadherence has been identified as an understudied, yet frequent, cause of relapse among patients with bipolar disorder. This study evaluated factors related to treatment adherence...

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..However, few data are available to inform the suicidality risk assessment of antidepressant use specifically in bipolar disorder...

..However, the public health challenge is to design and implement interventions that are sustainable in general clinical practice...

..The BDP provides an example of a multi-faceted collaborative practice model that can be manualized and implemented across multiple sites in a randomized controlled trial...

..If results are positive, this study will provide a reason to reconsider the prevailing trend toward limitation of ambulatory services that is characteristic of many managed care systems today...

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..This study a) extends investigation to a multisite public sector sample and b) tests a revised scoring algorithm that formally identifies patients in mixed states...

..In fact, the younger group showed a trend for decreased suicidality (P = .13). Thus, increased suicidality risk with paroxetine exposure does not extend to this other high-risk mood disordered population, even among younger individuals...

..Depressive and manic symptoms were positively, not inversely, correlated, and their co-occurrence was associated with worse quality of life. Implications for the DSM and ICD nosological systems are discussed...

..The goals of this initial study were (a) to determine whether the procedures could be exported from the authors to other therapists and (b) to quantify tolerability and impact of procedures on patients...

..A research agenda focusing on interventions that are sustainable in general clinical practice is of the highest priority...

..Implications for the study of economic outcome are discussed. In particular, we propose that economic outcome is a complex function of both patient and system factors, rather than simply being passively driven by disease severity...

..Although the results should be interpreted conservatively because of the observational nature of the study, the reorganization appeared to facilitate the positive changes that occurred over the study period...

..This article describes the development and content of the VA-Clinical Practice Guidelines for Bipolar Disorder, which are available in their entirety on the Journal Web site (http://www. psychiatrist.com)...

..The aim of this secondary analysis from a larger study was to identify the association between baseline variables and average treatment adherence over a subsequent three-year period...

..Part II (see companion article, this issue) reports clinical, functional, and overall cost outcomes of the trial...

..The ISS may be more sensitive to mood symptoms with prednisone than clinician-rated scales...

..The study addressed whether a collaborative model for chronic care, described in part I (this issue), improves outcome for bipolar disorder...

..Finally, he identifies the shortcomings and sources of potential bias in our evidence base, which is critical for an accurate reading of the literature now and in the future...

..Understanding barriers for treated populations is particularly important in optimizing care for high vulnerability populations, such as those with mental illness and the elderly...

..It is important that clinicians and care providers gather information related to patients' perceptions of the patient-provider relationship when designing or evaluating services aimed at enhancing treatment adherence...

..Recent data indicate high prevalence of both anxiety and substance comorbidity in bipolar disorder. However, few studies have utilized public sector samples, and only one has attempted to separate contributions of each type of comorbidity...

..The U.S. Systematic Treatment Enhancement Program for Bipolar Disorder compared one-year outcomes for bipolar I or II disorder from each of these racial-ethnic groups...

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..CONCLUSIONS: Rapid-cycling BD is associated with a latent hypofunction of the HPT system. This dysfunction becomes manifest with short-term lithium challenge...

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..We assessed whether patients with bipolar disorder received serum drug level and toxicity monitoring for mood stabilizers and assessment of cardiovascular disease (CVD)-related risk factors attributed to atypical antipsychotic medications...

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..However, the pattern of specific deficits has not been well studied, and the role of potential confounders has received no attention...

..Maintaining a beneficial therapeutic alliance with providers is one important strategy for improving adherence. We examine the association between adherence and therapeutic environment perceptions among veterans with bipolar disorder...

..This pilot study examined a bipolar disorder medical care model (BCM) and determined whether, compared with usual care, individuals randomly assigned to receive BCM care had improved medical and psychiatric outcomes...

..This study represents the first randomized trial of competing options for treatment-resistant bipolar depression and assesses the effectiveness and safety of antidepressant augmentation with lamotrigine, inositol, and risperidone...

..CONCLUSIONS: Although a majority of patients received guideline-concordant care for bipolar disorder, potential gaps in continuity of outpatient care may exist for African-American patients...

..The current report provides a context for interpreting studies resulting from STEP-BD by summarizing the baseline demographic and diagnostic characteristics of the first 1000 enrolled...

..Our findings highlight the need for greater clinical guidance and treatment options for patients with bipolar disorder and comorbidity...

..This trial evaluated the effectiveness of a multi-component care management program in a population-based sample of people with bipolar disorder...

..Bipolar patients with suicidal ideation may benefit from different treatment strategies depending on their prior attempt status...

..This report describes the design and implementation of a randomized trial evaluating a systematic program to improve quality and continuity of care for bipolar disorder...

..More research is needed to develop programs to improve outcomes for children with depression and adults with bipolar disorders...

..With this study, we provide new evidence as to the similarities and differences among these SSRI therapies with respect to the duration of use and health care costs...

..This report describes the development and evaluation of a brief measure for assessing patient perception of providers' support for self-management of bipolar disorder...

..This format will be particularly useful for studies that require processing of large numbers of ISSs, such as those that collect frequent ratings over long periods of time and/or those that utilize large samples...

..We investigated whether different forms of psychotherapy consisted of overlapping versus modality-specific ingredients...

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..To examine the relationship between changes in mood symptoms and changes in functioning or disability in people treated for bipolar disorder...

..This column describes how the partnership formed, key elements of its success, and challenges and opportunities to inform future research partnerships...

..In this article, we review the evidence for, and implications of, a high rate of comorbid posttraumatic stress disorder (PTSD) in individuals with bipolar disorder...

..The association between early childhood abuse and the course of illness, including psychiatric comorbidities, in adults with bipolar disorder has not been examined in a predominantly male or veteran population...

..Despite the availability of efficacious treatments, the long-term course of bipolar disorder is often unfavorable...

..Little is known about medical comorbidity or health-related quality of life (HRQOL) in bipolar disorder across the adult age span, especially in public sector patients...

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..Given limited health care resources, assessment of the value for the cost of second-generation antipsychotics relative to first-generation antipsychotics is critical for resource-allocation decisions...

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..We compared perceived access to and satisfaction with health care between patients diagnosed with serious mental illness (SMI: schizophrenia or bipolar disorder) and among those with no SMI diagnosis...