Rachel A Altura

Summary

Affiliation: Brown University
Country: USA

Publications

  1. doi request reprint XPO1 (CRM1) Inhibition Represses STAT3 Activation to Drive a Survivin-Dependent Oncogenic Switch in Triple-Negative Breast Cancer
    Yan Cheng
    Corresponding Author Rachel A Altura, Department of Pediatrics, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903
    Mol Cancer Ther 13:675-86. 2014
  2. pmc EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells
    Haijuan Wang
    Department of Pediatrics, Division of Pediatric Hematology Oncology, Brown University, Providence, RI 02903, USA
    BMC Mol Biol 11:66. 2010
  3. pmc Quantitative Phosphoproteomic Analysis Identifies Activation of the RET and IGF-1R/IR Signaling Pathways in Neuroblastoma
    Bradley D Denardo
    Division of Pediatric Hematology Oncology, Department of Pediatrics, The Warren Albert School of Medicine at Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 8:e82513. 2013
  4. pmc Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity
    Haijuan Wang
    Department of Pediatrics, Brown University and Rhode Island Hospital, Providence, Rhode Island 02903, USA
    J Biol Chem 285:36129-37. 2010
  5. pmc Histone deacetylase 6 (HDAC6) deacetylates survivin for its nuclear export in breast cancer
    Matthew T Riolo
    Department of Pediatrics, The Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island 02903, USA
    J Biol Chem 287:10885-93. 2012
  6. doi request reprint A novel missense mutation in MVK associated with MK deficiency and dyserythropoietic anemia
    Ayman Samkari
    Division of Hematology Oncology, Department of Pediatrics, Hasbro Children s Hospital and Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
    Pediatrics 125:e964-8. 2010

Collaborators

  • Kojo S J Elenitoba-Johnson
  • Michael P Holloway
  • Yan Cheng
  • Haijuan Wang
  • Zachary A Cooper
  • Ayman Samkari
  • Bradley D Denardo
  • Matthew T Riolo
  • Li Ma
  • Y Eugene Chin
  • Yosef Landesman
  • Dilara McCauley
  • Michael G Kauffman
  • Sharon Shacham
  • Kevin Nguyen
  • Kevin T Nguyen
  • Marcus B Valentine
  • Arthur Salomon
  • Qinqin Ji
  • Evgeny Yakirevich
  • Cesario Bianchi
  • Elisa Fermo
  • Fatma Dedeoglu
  • Kelly Cleveland
  • Andrea Kassai
  • Charlotte M Boney
  • Katarina Gambosova
  • Matthew Riolo
  • Diana O Treaba
  • Arturo Borzutzky
  • Denisse Izquierdo

Detail Information

Publications6

  1. doi request reprint XPO1 (CRM1) Inhibition Represses STAT3 Activation to Drive a Survivin-Dependent Oncogenic Switch in Triple-Negative Breast Cancer
    Yan Cheng
    Corresponding Author Rachel A Altura, Department of Pediatrics, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903
    Mol Cancer Ther 13:675-86. 2014
    ..Mol Cancer Ther; 13(3); 675-86. ©2014 AACR. ..
  2. pmc EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells
    Haijuan Wang
    Department of Pediatrics, Division of Pediatric Hematology Oncology, Brown University, Providence, RI 02903, USA
    BMC Mol Biol 11:66. 2010
    ..Here, we analyzed the effects of the β-cell mitogens IGF-1 and EGF on survivin regulation in the established pancreatic β-cell model cell lines, MIN6 and INS-1 and in primary mouse islets...
  3. pmc Quantitative Phosphoproteomic Analysis Identifies Activation of the RET and IGF-1R/IR Signaling Pathways in Neuroblastoma
    Bradley D Denardo
    Division of Pediatric Hematology Oncology, Department of Pediatrics, The Warren Albert School of Medicine at Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 8:e82513. 2013
    ..Furthermore, application of this previously unexploited technology in the clinic opens the possibility of providing a new wide-scale molecular signature to assess disease progression and prognosis. ..
  4. pmc Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity
    Haijuan Wang
    Department of Pediatrics, Brown University and Rhode Island Hospital, Providence, Rhode Island 02903, USA
    J Biol Chem 285:36129-37. 2010
    ....
  5. pmc Histone deacetylase 6 (HDAC6) deacetylates survivin for its nuclear export in breast cancer
    Matthew T Riolo
    Department of Pediatrics, The Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island 02903, USA
    J Biol Chem 287:10885-93. 2012
    ..Together, these data imply that HDAC6 deacetylates survivin to regulate its nuclear export, a feature that may provide a novel target for patients with ER+ breast cancer...
  6. doi request reprint A novel missense mutation in MVK associated with MK deficiency and dyserythropoietic anemia
    Ayman Samkari
    Division of Hematology Oncology, Department of Pediatrics, Hasbro Children s Hospital and Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
    Pediatrics 125:e964-8. 2010
    ..Treatment with corticosteroids and colchicine directed at controlling the autoinflammatory disease resulted in improvement of the anemia...