Alexei S Soares

Summary

Affiliation: Brookhaven National Laboratory
Country: USA

Publications

  1. ncbi request reprint Experimental methods for measuring accurate high-amplitude phases and their importance in isomorphous replacement experiments
    Alexei S Soares
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Acta Crystallogr D Biol Crystallogr 61:1521-7. 2005
  2. pmc Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site
    John H Carra
    United States Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702, USA
    BMC Struct Biol 7:72. 2007
  3. pmc Acoustically mounted microcrystals yield high-resolution X-ray structures
    Alexei S Soares
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973 5000, USA
    Biochemistry 50:4399-401. 2011
  4. pmc Acoustic methods for high-throughput protein crystal mounting at next-generation macromolecular crystallographic beamlines
    Christian G Roessler
    Photon Sciences Directorate, Brookhaven National Laboratory, Upton, NY 11973, USA
    J Synchrotron Radiat 20:805-8. 2013
  5. ncbi request reprint Integrated software for macromolecular crystallography synchrotron beamlines II: revision, robots and a database
    John M Skinner
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Acta Crystallogr D Biol Crystallogr 62:1340-7. 2006
  6. pmc Macromolecular crystallography beamline X25 at the NSLS
    Annie Heroux
    Photon Sciences Directorate, Brookhaven National Laboratory, PO Box 5000, Upton, NY 11973 5000, USA
    J Synchrotron Radiat 21:627-32. 2014
  7. ncbi request reprint Mail-in crystallography program at Brookhaven National Laboratory's National Synchrotron Light Source
    Howard Robinson
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Acta Crystallogr D Biol Crystallogr 62:1336-9. 2006
  8. ncbi request reprint Three-beam interference is a sensitive measure of the efficacy of macromolecular refinement techniques
    Alexei S Soares
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Acta Crystallogr D Biol Crystallogr 59:1716-24. 2003
  9. pmc Crystal structure of a complex between the phosphorelay protein YPD1 and the response regulator domain of SLN1 bound to a phosphoryl analog
    Xiaodong Zhao
    Department of Chemistry and Biochemistry, University of Oklahoma, 620 Parrington Oval, Norman, OK 73019, USA
    J Mol Biol 375:1141-51. 2008
  10. ncbi request reprint Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin
    Moh d A Salameh
    Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida 32224, USA
    J Biol Chem 283:4115-23. 2008

Collaborators

  • Allen M Orville
  • Marc Allaire
  • Joseph Olechno
  • Michael Becker
  • Annie Heroux
  • Christian G Roessler
  • John M Skinner
  • Daniel M Copeland
  • Dieter K Schneider
  • Robert M Sweet
  • Howard H Robinson
  • Xiaodong Zhao
  • Moh d A Salameh
  • John H Carra
  • Ann H West
  • Howard Robinson
  • Grace Shea-McCarthy
  • Michael Skinner
  • Stuart F Myers
  • Lonny E Berman
  • Steven Lamarra
  • Leon Flaks
  • Richard Buono
  • Matthew L Cowan
  • Joseph Dvorak
  • Richard Stearns
  • Anthony Kuczewski
  • Richard Ellson
  • Alexandra Hockla
  • Evette S Radisky
  • Charles B Millard
  • Colleen A McHugh
  • Sheila Mulligan
  • Leeann M Machiesky
  • Heinz Bosshard
  • Robert Sweet
  • Matt Cowan
  • Rick Buono
  • William Nolan
  • George B Richter-Addo

Detail Information

Publications11

  1. ncbi request reprint Experimental methods for measuring accurate high-amplitude phases and their importance in isomorphous replacement experiments
    Alexei S Soares
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Acta Crystallogr D Biol Crystallogr 61:1521-7. 2005
    ....
  2. pmc Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site
    John H Carra
    United States Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702, USA
    BMC Struct Biol 7:72. 2007
    ....
  3. pmc Acoustically mounted microcrystals yield high-resolution X-ray structures
    Alexei S Soares
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973 5000, USA
    Biochemistry 50:4399-401. 2011
    ..X-ray diffraction data sets merged from several micrometer-sized crystals are used to determine 1.8 Ǻ resolution crystal structures...
  4. pmc Acoustic methods for high-throughput protein crystal mounting at next-generation macromolecular crystallographic beamlines
    Christian G Roessler
    Photon Sciences Directorate, Brookhaven National Laboratory, Upton, NY 11973, USA
    J Synchrotron Radiat 20:805-8. 2013
    ..Future developments and implementation will focus on achieving ejection and translation of single droplets at a rate of over one hundred per second...
  5. ncbi request reprint Integrated software for macromolecular crystallography synchrotron beamlines II: revision, robots and a database
    John M Skinner
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Acta Crystallogr D Biol Crystallogr 62:1340-7. 2006
    ..This has included construction of a relational database to organize all details of the experiment and incorporation of a robotic specimen changer to provide automation for high-throughput applications...
  6. pmc Macromolecular crystallography beamline X25 at the NSLS
    Annie Heroux
    Photon Sciences Directorate, Brookhaven National Laboratory, PO Box 5000, Upton, NY 11973 5000, USA
    J Synchrotron Radiat 21:627-32. 2014
    ..All major components beginning with the radiation source, and continuing along the beamline and its experimental hutch, have changed to produce a state-of-the-art facility for the scientific community...
  7. ncbi request reprint Mail-in crystallography program at Brookhaven National Laboratory's National Synchrotron Light Source
    Howard Robinson
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Acta Crystallogr D Biol Crystallogr 62:1336-9. 2006
    ..It also accelerates the innovation of new productivity tools, which benefit users who come to NSLS beamlines as well as those who use the mail-in program...
  8. ncbi request reprint Three-beam interference is a sensitive measure of the efficacy of macromolecular refinement techniques
    Alexei S Soares
    Biology Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Acta Crystallogr D Biol Crystallogr 59:1716-24. 2003
    ..6 degrees. Modeling the discrete disorder of four amino acids accounted for an additional 0.5 degrees improvement and the final individual phase error was 11.6 degrees...
  9. pmc Crystal structure of a complex between the phosphorelay protein YPD1 and the response regulator domain of SLN1 bound to a phosphoryl analog
    Xiaodong Zhao
    Department of Chemistry and Biochemistry, University of Oklahoma, 620 Parrington Oval, Norman, OK 73019, USA
    J Mol Biol 375:1141-51. 2008
    ..The ground-state structure presented here suggests that phosphoryl transfer will likely proceed through an associative mechanism involving the formation of a pentacoordinate phosphorus intermediate...
  10. ncbi request reprint Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin
    Moh d A Salameh
    Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida 32224, USA
    J Biol Chem 283:4115-23. 2008
    ..Our model predicts that these deleterious interactions accelerate leaving group dissociation and deacylation...
  11. ncbi request reprint Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin
    Daniel M Copeland
    Department of Chemistry and Biochemistry, University of Oklahoma, 620 Parrington Oval, Norman, OK 73019, USA
    J Inorg Biochem 100:1413-25. 2006
    ..13 A. This difference in FeNO conformations as a function of preparative method is reproducible, and suggests a role of the distal pocket in hh MbIINO in stabilizing local FeNO conformational minima...