Helene D Benveniste

Summary

Affiliation: Brookhaven National Laboratory
Country: USA

Publications

  1. ncbi request reprint MR microscopy and high resolution small animal MRI: applications in neuroscience research
    Helene Benveniste
    Medical Department, Brookhaven National Laboratory, Building 490, 30 Bell Avenue, Upton, NY 11793, USA
    Prog Neurobiol 67:393-420. 2002
  2. ncbi request reprint Anatomical and functional phenotyping of mice models of Alzheimer's disease by MR microscopy
    Helene Benveniste
    Brookhaven National Laboratory, Medical Department, Bldg 490, 30 Bell Avenue, Upton, NY 11973, USA
    Ann N Y Acad Sci 1097:12-29. 2007
  3. doi request reprint Glutamate, microdialysis, and cerebral ischemia: lost in translation?
    Helene Benveniste
    Department of Anesthesiology, Stony Brook University, New York 11794, USA
    Anesthesiology 110:422-5. 2009
  4. ncbi request reprint Translational neuroscience and magnetic-resonance microscopy
    Helene Benveniste
    Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Lancet Neurol 5:536-44. 2006
  5. pmc Cocaine is pharmacologically active in the nonhuman primate fetal brain
    Helene Benveniste
    Department of Anesthesiology, Stony Brook University, Stony Brook, NY 11794, USA
    Proc Natl Acad Sci U S A 107:1582-7. 2010
  6. ncbi request reprint Maternal and fetal 11C-cocaine uptake and kinetics measured in vivo by combined PET and MRI in pregnant nonhuman primates
    Helene Benveniste
    Medical Department, Brookhaven National Laboratory, Upton, New York 11793, USA
    J Nucl Med 46:312-20. 2005
  7. ncbi request reprint Maternal-fetal in vivo imaging: a combined PET and MRI study
    Helene Benveniste
    Medical Department, Brookhaven National Laboratory, Upton, New York 11793, USA
    J Nucl Med 44:1522-30. 2003
  8. pmc Differential effects of anesthetics on cocaine's pharmacokinetic and pharmacodynamic effects in brain
    Congwu Du
    Department of Anesthesiology, State University of New York at Stony Brook, Stony Brook, NY, USA
    Eur J Neurosci 30:1565-75. 2009
  9. doi request reprint Computed tomography of amyloid plaques in a mouse model of Alzheimer's disease using diffraction enhanced imaging
    Dean M Connor
    National Synchrotron Light Source, Brookhaven National Laboratory, Upton, NY 11973, USA
    Neuroimage 46:908-14. 2009
  10. pmc The effect of intravenous lidocaine on brain activation during non-noxious and acute noxious stimulation of the forepaw: a functional magnetic resonance imaging study in the rat
    Zhongchi Luo
    Departments of Biomedical Engineering, State University of New York at Stony Brook, Stony Brook, New York, USA
    Anesth Analg 108:334-44. 2009

Research Grants

Collaborators

Detail Information

Publications19

  1. ncbi request reprint MR microscopy and high resolution small animal MRI: applications in neuroscience research
    Helene Benveniste
    Medical Department, Brookhaven National Laboratory, Building 490, 30 Bell Avenue, Upton, NY 11793, USA
    Prog Neurobiol 67:393-420. 2002
    ..We also take a critical look at the biological information that small animal (rodent) MR imaging has provided in neuroscience research...
  2. ncbi request reprint Anatomical and functional phenotyping of mice models of Alzheimer's disease by MR microscopy
    Helene Benveniste
    Brookhaven National Laboratory, Medical Department, Bldg 490, 30 Bell Avenue, Upton, NY 11973, USA
    Ann N Y Acad Sci 1097:12-29. 2007
    ..We will present MRM data of brain and cardiac phenotyping in transgenic mouse models with behavioral deficits...
  3. doi request reprint Glutamate, microdialysis, and cerebral ischemia: lost in translation?
    Helene Benveniste
    Department of Anesthesiology, Stony Brook University, New York 11794, USA
    Anesthesiology 110:422-5. 2009
    ..It is suggested that the large increase in the content of extracellular glutamate and aspartate in the hippocampus induced by the ischemia may be one of the causal factors in the damage to certain neurons observed after ischemia...
  4. ncbi request reprint Translational neuroscience and magnetic-resonance microscopy
    Helene Benveniste
    Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    Lancet Neurol 5:536-44. 2006
    ..Two of the major magnetic-resonance microscopy applications in the neurosciences-structural and functional magnetic-resonance microscopy-will be reviewed...
  5. pmc Cocaine is pharmacologically active in the nonhuman primate fetal brain
    Helene Benveniste
    Department of Anesthesiology, Stony Brook University, Stony Brook, NY 11794, USA
    Proc Natl Acad Sci U S A 107:1582-7. 2010
    ....
  6. ncbi request reprint Maternal and fetal 11C-cocaine uptake and kinetics measured in vivo by combined PET and MRI in pregnant nonhuman primates
    Helene Benveniste
    Medical Department, Brookhaven National Laboratory, Upton, New York 11793, USA
    J Nucl Med 46:312-20. 2005
    ..Here, we evaluate the utility of PET to measure the uptake and distribution of (11)C-cocaine in the third-trimester fetus...
  7. ncbi request reprint Maternal-fetal in vivo imaging: a combined PET and MRI study
    Helene Benveniste
    Medical Department, Brookhaven National Laboratory, Upton, New York 11793, USA
    J Nucl Med 44:1522-30. 2003
    ....
  8. pmc Differential effects of anesthetics on cocaine's pharmacokinetic and pharmacodynamic effects in brain
    Congwu Du
    Department of Anesthesiology, State University of New York at Stony Brook, Stony Brook, NY, USA
    Eur J Neurosci 30:1565-75. 2009
    ....
  9. doi request reprint Computed tomography of amyloid plaques in a mouse model of Alzheimer's disease using diffraction enhanced imaging
    Dean M Connor
    National Synchrotron Light Source, Brookhaven National Laboratory, Upton, NY 11973, USA
    Neuroimage 46:908-14. 2009
    ..Several anatomical structures, including hippocampal subregions and white matter tracks, were also observed. Thus, DEI has strong promise in early diagnosis of AD, as well as general studies of the mouse brain...
  10. pmc The effect of intravenous lidocaine on brain activation during non-noxious and acute noxious stimulation of the forepaw: a functional magnetic resonance imaging study in the rat
    Zhongchi Luo
    Departments of Biomedical Engineering, State University of New York at Stony Brook, Stony Brook, New York, USA
    Anesth Analg 108:334-44. 2009
    ..Here, we therefore characterized the effect of systemic lidocaine on the brain's response to innocuous and acute noxious stimulation in the rat using functional magnetic resonance imaging (fMRI)...
  11. pmc The effects of cocaine on regional brain glucose metabolism is attenuated in dopamine transporter knockout mice
    Panayotis K Thanos
    Behavioral Neuropharmacology Lab, Medical Department, Brookhaven National Laboratory, Upton, New York 11973 5000, USA
    Synapse 62:319-24. 2008
    ..The greater baseline metabolism in DAT(-/-) than DAT(+/+) mice in cerebellum (brain region mostly devoid of DAT) suggests that dopamine indirectly regulates activity of these brain regions...
  12. pmc PET studies of d-methamphetamine pharmacokinetics in primates: comparison with l-methamphetamine and ( --)-cocaine
    Joanna S Fowler
    Brookhaven National Laboratory, Upton, New York, USA
    J Nucl Med 48:1724-32. 2007
    ....
  13. ncbi request reprint Effects of chronic oral methylphenidate on cocaine self-administration and striatal dopamine D2 receptors in rodents
    Panayotis K Thanos
    Behavioral Neuropharmacology and Neuroimaging Lab, Medical Department, Building 490, Brookhaven National Laboratory, Upton, NY 11973 5000, United States
    Pharmacol Biochem Behav 87:426-33. 2007
    ....
  14. ncbi request reprint Cocaine increases the intracellular calcium concentration in brain independently of its cerebrovascular effects
    Congwu Du
    Medical Department, Brookhaven National Laboratory, Upton, New York 11973 5000, USA
    J Neurosci 26:11522-31. 2006
    ..These findings support the use of calcium channel blockers as a strategy to minimize the neurotoxic effects of cocaine...
  15. pmc Interlaced x-ray microplanar beams: a radiosurgery approach with clinical potential
    F Avraham Dilmanian
    Medical Department, National Synchrotron Light Source, Brookhaven National Laboratory, Upton, NY 11973, USA
    Proc Natl Acad Sci U S A 103:9709-14. 2006
    ..These findings strongly suggest potential application of interlaced microbeams to treat tumors or to ablate nontumorous abnormalities with minimal damage to surrounding normal tissue...
  16. ncbi request reprint Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11C]nisox
    Yu Shin Ding
    Chemistry Department, Brookhaven National Laboratory, Upton, New York 11973, USA
    J Neurochem 94:337-51. 2005
    ..Thus, to our knowledge (S,S)-[11C]MRB remains by far the most promising NET ligand for PET studies...
  17. ncbi request reprint Simultaneous detection of blood volume, oxygenation, and intracellular calcium changes during cerebral ischemia and reperfusion in vivo using diffuse reflectance and fluorescence
    Congwu Du
    Brookhaven National Laboratory, Medical Department, Upton, New York 11973 5000, USA
    J Cereb Blood Flow Metab 25:1078-92. 2005
    ....
  18. pmc Transient focal ischemia results in persistent and widespread neuroinflammation and loss of glutamate NMDA receptors
    Jasbeer Dhawan
    Medical Department, Brookhaven National Laboratory, Building 490, Upton, NY 11973, USA
    Neuroimage 51:599-605. 2010
    ..Persistent, bilateral loss of NMDAR, probably reflecting receptor down regulation and internalization, may be responsible for some of the effects of stroke on cognitive function which cannot be explained by infarction alone...
  19. ncbi request reprint Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain
    Louis N Manganas
    SUNY Stony Brook, Stony Brook, NY 11794, USA
    Science 318:980-5. 2007
    ..Our findings thus open the possibility of investigating the role of NPCs and neurogenesis in a wide variety of human brain disorders...

Research Grants4

  1. A 3D C57BL6/J MOUSE BRAIN ATLAS MAGNETIC RESONANCE MICRO
    Helene Benveniste; Fiscal Year: 2003
    ..Further, a probabilistic (averaged from many brain specimens) atlas with error estimations will be created for registration of actual gene-expression data. ..