D S Greene

Summary

Affiliation: Bristol-Myers Squibb
Country: USA

Publications

  1. ncbi request reprint Clinical pharmacokinetics of nefazodone
    D S Greene
    Metabolism and Pharmacokinetics Department, Bristol Myers Squibb, Princeton, New Jersey, USA
    Clin Pharmacokinet 33:260-75. 1997
  2. ncbi request reprint Assessment of effect of food, gender, and intra-subject variability in the pharmacokinetics of avitriptan
    P H Marathe
    Department of Metabolism and Pharmacokinetics, Bristol Myers Squibb Company, Princeton, NJ, USA
    Biopharm Drug Dispos 19:153-7. 1998
  3. ncbi request reprint Evaluation of the effect of food on the pharmacokinetics of avitriptan
    P H Marathe
    Department of Metabolism and Pharmacokinetics and Biostatistics and Data Management, Bristol Myers Squibb Company, Pharmaceutical Research Institute, Princeton, NJ 08543, USA
    Biopharm Drug Dispos 19:381-94. 1998
  4. ncbi request reprint Disposition of radiolabeled ifetroban in rats, dogs, monkeys, and humans
    R C Dockens
    Department of Metabolism and Pharmacokinetics, Bristol Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey, USA
    Drug Metab Dispos 28:973-80. 2000
  5. pmc Effect of altered gastric emptying and gastrointestinal motility on metformin absorption
    P H Marathe
    Department of Metabolism and Pharmacokinetics, Bristol Myers Squibb Company, Princeton, NJ 08543, USA
    Br J Clin Pharmacol 50:325-32. 2000

Detail Information

Publications5

  1. ncbi request reprint Clinical pharmacokinetics of nefazodone
    D S Greene
    Metabolism and Pharmacokinetics Department, Bristol Myers Squibb, Princeton, New Jersey, USA
    Clin Pharmacokinet 33:260-75. 1997
    ..No clinically significant interaction was observed when nefazodone was administered with lorazepam, lithium, alcohol, cimetidine, warfarin, theophylline or propranolol...
  2. ncbi request reprint Assessment of effect of food, gender, and intra-subject variability in the pharmacokinetics of avitriptan
    P H Marathe
    Department of Metabolism and Pharmacokinetics, Bristol Myers Squibb Company, Princeton, NJ, USA
    Biopharm Drug Dispos 19:153-7. 1998
    ..The intra- and inter-subject variability (%CV) in the Cmax and AUC of avitriptan in the fasted and fed conditions ranged from 10 to 60% in male and female subjects...
  3. ncbi request reprint Evaluation of the effect of food on the pharmacokinetics of avitriptan
    P H Marathe
    Department of Metabolism and Pharmacokinetics and Biostatistics and Data Management, Bristol Myers Squibb Company, Pharmaceutical Research Institute, Princeton, NJ 08543, USA
    Biopharm Drug Dispos 19:381-94. 1998
    ..Thus, it appears that avitriptan absorption and bioavailability are highly sensitive to presence of food in the stomach and any food-related changes in gastric emptying time and gastrointestinal motility...
  4. ncbi request reprint Disposition of radiolabeled ifetroban in rats, dogs, monkeys, and humans
    R C Dockens
    Department of Metabolism and Pharmacokinetics, Bristol Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey, USA
    Drug Metab Dispos 28:973-80. 2000
    ..Approximately 40 to 50% of the radioactivity in rat and dog plasma was accounted for by parent drug whereas, in humans, approximately 60% of the plasma radioactivity was accounted for by ifetroban acylglucuronide...
  5. pmc Effect of altered gastric emptying and gastrointestinal motility on metformin absorption
    P H Marathe
    Department of Metabolism and Pharmacokinetics, Bristol Myers Squibb Company, Princeton, NJ 08543, USA
    Br J Clin Pharmacol 50:325-32. 2000
    ..The purpose of this in vivo human study was to assess the effect of altered gastric emptying and gastrointestinal motility on the absorption of metformin in healthy subjects...