Genomes and Genes

Species

James R Burke

Summary

Affiliation: Bristol-Myers Squibb
Country: USA

Publications

  1. Tokarski J, Zupa Fernandez A, Tredup J, Pike K, Chang C, Xie D, et al. Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. J Biol Chem. 2015;290:11061-74 pubmed publisher
    ..Tyk2 pseudokinase stabilizers, therefore, represent a novel approach to the design of potent and selective agents for the treatment of autoimmunity. ..