Research Topics
Species | E D BiglerSummaryAffiliation: Brigham Young University Country: USA Publications
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Detail Information
Publications
Head circumference and height in autism: a study by the Collaborative Program of Excellence in AutismJanet E Lainhart
Department of Psychiatry, The Brain Institute at the University of Utah, Salt Lake City, Utah 84108, USA
Am J Med Genet A 140:2257-74. 2006..The wide distribution of head circumference in autism has major implications for genetic, neuroimaging, and other neurobiological research...
Neuropathology of mild traumatic brain injury: relationship to neuroimaging findingsErin D Bigler
Department of Psychology, Brigham Young University, Provo, UT, USA
Brain Imaging Behav 6:108-36. 2012..Historical milestones in understanding the neuropathology of mTBI are reviewed along with implications for future directions in the examination of neuroimaging and neuropathological correlates of TBI...- White matter lesions, quantitative magnetic resonance imaging, and dementiaErin D Bigler
Bringham Young University, Provo, Utah, USA
Alzheimer Dis Assoc Disord 16:161-70. 2002..There were no significant qualitative or quantitative findings related to presence of the epsilon4 allele and MMSE performance. The role of WMLs in aging and dementia is discussed... - Neuropsychological results and neuropathological findings at autopsy in a case of mild traumatic brain injuryErin D Bigler
Departments of Psychology and Neuroscience, Brigham Young University, Provo, Utah 84602, USA
J Int Neuropsychol Soc 10:794-806. 2004..This case demonstrates the presence of subtle neuropathological changes in the brain of a patient who sustained a mild TBI and was still symptomatic for the residual effects of the injury 7 months post injury when he unexpectedly died... - Anterior and middle cranial fossa in traumatic brain injury: relevant neuroanatomy and neuropathology in the study of neuropsychological outcomeErin D Bigler
Department of Psychology, Brigham Young University, UT 84602, USA
Neuropsychology 21:515-31. 2007..How neuropsychological deficits result from damage to these areas is reviewed and discussed... - Neurobiology and neuropathology underlie the neuropsychological deficits associated with traumatic brain injuryErin D Bigler
Departments of Psychology and Neuroscience, Brigham Young University, Provo, Utah 84602, USA
Arch Clin Neuropsychol 18:595-621; discussion 623-7. 2003..The article also opines on the future role and importance that neuroimaging will play in neuropsychological practice, particularly functional neuroimaging methods... - Role of white matter lesions, cerebral atrophy, and APOE on cognition in older persons with and without dementia: the Cache County, Utah, study of memory and agingErin D Bigler
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
Neuropsychology 17:339-52. 2003..APOE genotype was unrelated to imaging or neuropsychological performance. Neuropsychological relationships with neuroimaging findings depend on the qualitative or quantitative method used... - Superior temporal gyrus, language function, and autismErin D Bigler
Departments of Psychology and Neuroscience, Brigham Young University, Provo, UT 84602, USA
Dev Neuropsychol 31:217-38. 2007..Taken together, these findings suggest a possible failure in left hemisphere lateralization of language function involving the STG in autism... - Volumetric and voxel-based morphometry findings in autism subjects with and without macrocephalyErin D Bigler
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
Dev Neuropsychol 35:278-95. 2010..Current theories of brain overgrowth and their importance in the development of autism are discussed in the context of these findings... - Dementia, asymmetry of temporal lobe structures, and apolipoprotein E genotype: relationships to cerebral atrophy and neuropsychological impairmentErin D Bigler
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
J Int Neuropsychol Soc 8:925-33. 2002..These findings were interpreted as representing cognitive reserve effects where larger volume was protective against impairment. The role of asymmetry research in understanding neuropsychological performance in dementia is discussed... - Neuropsychology and clinical neuroscience of persistent post-concussive syndromeErin D Bigler
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
J Int Neuropsychol Soc 14:1-22. 2008.... - A motion to exclude and the 'fixed' versus 'flexible' battery in 'forensic' neuropsychology: challenges to the practice of clinical neuropsychologyErin D Bigler
Department of Psychology, 1001 SWKT, Brigham Young University, Provo, UT 84602, United States
Arch Clin Neuropsychol 22:45-51. 2007..The critical issues of this argument for clinical neuropsychological practice are reviewed... - Quantitative magnetic resonance imaging in traumatic brain injuryE D Bigler
Department of Psychology, Brigham Young University, Provo, Utah, USA
J Head Trauma Rehabil 16:117-34. 2001..Various clinical caveats are provided including how quantitative neuroimaging findings can be used clinically and in predicting rehabilitation outcome. The future of quantitative neuroimaging also is discussed... - Brain volume, intracranial volume, and dementiaE D Bigler
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
Invest Radiol 36:539-46. 2001.... - Neuroimaging and neuropathology of TBIErin D Bigler
Department of Psychology and Neuroscience Center, Brigham Young University, Provo, Utah, USA
NeuroRehabilitation 28:63-74. 2011..The aim of this review is to provide pathological confirmation of observable neuroimaging abnormalities that relate directly to trauma-induced effects of the injury... - The temporal stem in traumatic brain injury: preliminary findingsErin D Bigler
Department of Psychology, Brigham Young University, Provo, UT 84602, USA
Brain Imaging Behav 4:270-82. 2010..The need for future studies specifically examining the role of TS injury in TBI is emphasized... - Cerebral volume loss, cognitive deficit and neuropsychological performance: comparative measures of brain atrophy: I. DementiaErin D Bigler
Department of Psychiatry and Neuroscience, Brigham Young University, Provo, Utah 84602, USA
J Int Neuropsychol Soc 10:442-52. 2004.... - Temporal lobe morphology in normal aging and traumatic brain injuryErin D Bigler
Department of Psychology, 1082 SWKT, Brigham Young University, Provo, Utah 84602, USA
AJNR Am J Neuroradiol 23:255-66. 2002..Gyral volume did not decrease, although it was related to memory performance... - Clinical rating of cortical atrophy and cognitive correlates following traumatic brain injuryAdam G Bergeson
Neuroscience Center, Brigham Young University, Provo, UT 84602-5543, USA
Clin Neuropsychol 18:509-20. 2004..These findings indicate that clinical ratings of trauma-induced atrophy can be reliably performed and are associated with neuropsychological outcome and quantitative measures of cerebral atrophy... - Autopsy-confirmed Alzheimer's disease versus clinically diagnosed Alzheimer's disease in the Cache County Study on Memory and Aging: a comparison of quantitative MRI and neuropsychological findingsMichael A Fearing
Brigham Young University, Provo, UT 84602 5543, USA
J Clin Exp Neuropsychol 29:553-60. 2007.... - Temporal lobe, autism, and macrocephalyErin D Bigler
Department of Psychology and Neuroscience, Brigham Young University, Provo, UT, USA
AJNR Am J Neuroradiol 24:2066-76. 2003..Temporal lobe abnormalities that may be associated with autism are likely to be more related to functional organization within the temporal lobe than to any gross volumetric difference... - Different patterns of cerebral activation in genuine and malingered cognitive effort during performance on the Word Memory TestJames D Larsen
Psychology Department, Brigham Young University, Provo, Utah 84602, USA
Brain Inj 24:89-99. 2010..The second purpose was to investigate the neural networks involved during intentional malingering on the WMT... - Neuroimaging in psychiatryD G Weight
Department of Psychology, Brigham Young University, Provo, Utah, USA
Psychiatr Clin North Am 21:725-59, v. 1998..Examples of normal and pathologic images illustrate actual cases and examples of the newer imaging technologies... - Verbal memory deficits associated with fornix atrophy in carbon monoxide poisoningS R Kesler
Psychology Department, Brigham Young University, Provo, Utah 84602, USA
J Int Neuropsychol Soc 7:640-6. 2001..This study indicates that CO results in brain damage and cognitive impairments in the absence of lesions and other neuroanatomic markers... - Quantitative magnetic resonance image analysis of the cerebellum in macrocephalic and normocephalic children and adults with autismHoward B Cleavinger
Department of Psychology, Brigham Young University, Provo, Utah, USA
J Int Neuropsychol Soc 14:401-13. 2008..In autism, with and without macrocephaly, cerebellar structures were found to be proportional to head size and did not differ from typically developing subjects... - Objective documentation of traumatic brain injury subsequent to mild head trauma: multimodal brain imaging with MEG, SPECT, and MRIJeffrey David Lewine
Department of Radiology, The University of Utah School of Medicine, Salt Lake City, Utah, USA
J Head Trauma Rehabil 22:141-55. 2007.... - Diffuse damage in pediatric traumatic brain injury: a comparison of automated versus operator-controlled quantification methodsErin D Bigler
Department of Psychology, Brigham Young University, Provo, UT 84602, USA
Neuroimage 50:1017-26. 2010.... - Functional neuroimaging evidence for high cognitive effort on the Word Memory Test in the absence of external incentivesMark D Allen
Psychology Department, Brigham Young University, Provo, UT 84602, USA
Brain Inj 21:1425-8. 2007.... - Traumatic brain injury and forensic neuropsychologyErin D Bigler
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA erin
J Head Trauma Rehabil 24:76-87. 2009..This article introduces each topic area covered in this special edition... - Brain integrity and cerebral atrophy in Vietnam combat veterans with and without posttraumatic stress disorderDawson W Hedges
Department of Psychology, Brigham Young University, Provo, UT 84602, USA
Neurocase 13:402-10. 2007..Both groups showed heterogeneity in cerebral atrophy... - Reduced hippocampal volume in alcohol and substance naïve Vietnam combat veterans with posttraumatic stress disorderDawson W Hedges
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
Cogn Behav Neurol 16:219-24. 2003..This pilot study was undertaken to exclude the effects of alcohol and other substances on brain morphology in posttraumatic stress disorder... - Anoxic versus traumatic brain injury: amount of tissue loss, not etiology, alters cognitive and emotional functionRamona O Hopkins
Psychology Department, Neuroscience Center, Brigham Young University, Provo, UT 84602, USA
Neuropsychology 19:233-42. 2005..In the absence of localized lesions, the amount of neural tissue loss, rather than etiology, may be the critical factor in neuropsychological outcome... - Macrocephaly, corpus callosum morphology, and autismSara A Rice
Department of Psychology and Neuroscience, Brigham Young University, Provo, UT 84602, USA
J Child Neurol 20:34-41. 2005..These findings suggest no unique difference in overall regional corpus callosum surface area in autism with macrocephaly... - Prevalence of white matter hyperintensities in a young healthy populationRamona O Hopkins
Psychology Department, Brigham Young University, Provo, UT 84602, USA
J Neuroimaging 16:243-51. 2006..We assessed the prevalence of WMHs in a cohort of younger healthy subjects... - Neurobehavioral sequelae of child sexual abuseCorinna Porter
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
Child Neuropsychol 11:203-20. 2005..Results are discussed in the context of stress effects on cognition and the potential resiliency of cognitive function in children undergoing treatment for sexual abuse... 
Diffuse changes in cortical thickness in pediatric moderate-to-severe traumatic brain injuryTricia L Merkley
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
J Neurotrauma 25:1343-5. 2008..TBI-induced cortical thickness reductions are probably due to a combination of focal and diffuse effects and have implications for the neurobehavioral sequelae of TBI...- Traumatic brain injury and atrophy of the cingulate gyrusRyan Yount
Department of Psychology, University of San Francisco, San Francisco, CA, USA
J Neuropsychiatry Clin Neurosci 14:416-23. 2002..Despite significant atrophy of the posterior CG, neuropsychological performance was not related to changes in CG cross-sectional surface area in the TBI subjects. This apparent discrepancy is discussed... - Normative data on trail making test for neurologically normal, Chinese-speaking adultsLei Lu
Department of Psychology, Brigham Young University, Provo, Utah 84604, USA
Appl Neuropsychol 9:219-25. 2002..Findings also demonstrate a need for norms adjusted for both age and education for adults whose primary language is Chinese... - Memory performance of children with dyslexia: a comparative analysis of theoretical perspectivesNancy-Louise Howes
Department of Psychology, Utah State Hospital, Provo 84603-0270, USA
J Learn Disabil 36:230-46. 2003..The phonological-core variable-difference model accounted for more variance in memory performance than either of the other two models... - Limitations of mild traumatic brain injury meta-analysesJon L Pertab
Department of Psychology and Neuroscience Center, Brigham Young University, Utah 84602, USA
Brain Inj 23:498-508. 2009.... - Memory and learning in pediatric traumatic brain injury: a review and examination of moderators of outcomeRenee Lajiness-O'Neill
Department of Psychology, Eastern Michigan University, 537 F Mark Jefferson, Ypsilanti, MI 48197, USA
Appl Neuropsychol 17:83-92. 2010..Critical factors affecting outcome are explored with an emphasis on an examination of age at injury. The article closes with discussion of current evidence-based interventions for deficits in memory and learning following pediatric TBI... - A retrospective fetal ultrasound study of brain size in autismKyle Hobbs
School of Medicine, University of Utah, Salt Lake City, Utah, USA
Biol Psychiatry 62:1048-55. 2007..Fetal head circumference (HC) and biparietal diameter (BPD) are highly correlated with fetal brain volume and are measured on fetal ultrasounds... - White matter hyperintensities and neuropsychological outcome following carbon monoxide poisoningR B Parkinson
Psychology Department, Brigham Young University, Provo, UT 84602-5543, USA
Neurology 58:1525-32. 2002..The WMH were not related to CO poisoning severity. The WMH occurred in both the periventricular and the centrum semiovale regions; however, only those in the centrum semiovale were significantly associated with cognitive impairments... - Technology in the assessment of learning disabilityE D Bigler
Brigham Young University, Department of Psychology, Provo, UT 84602 5543, USA
J Learn Disabil 31:67-82. 1998..To date, no diagnostic conclusions have been drawn utilizing these methods in the assessment of the neurobiologic basis to LD... - Evaluating the relationship between memory functioning and cingulum bundles in acute mild traumatic brain injury using diffusion tensor imagingTrevor C Wu
Department of Psychology, Brigham Young University, Provo, Utah, USA
J Neurotrauma 27:303-7. 2010..These preliminary findings indicate that cingulate injury likely contributes to the cognitive sequelae seen during the early phase post-mTBI... - Day-of-injury computerized tomography, rehabilitation status, and development of cerebral atrophy in persons with traumatic brain injuryErin D Bigler
Department of Psychology, Brigham Young University, Provo, Utah 84602, USA
Am J Phys Med Rehabil 85:793-806. 2006..Presence of DOI CT abnormalities were associated with the development of cerebral atrophy, which was associated with poorer rehabilitation discharge DRS and FIM scores... - Quantitative temporal lobe differences: autism distinguished from controls using classification and regression tree analysisE Shannon Neeley
Department of Statistics, Brigham Young University, Provo, UT 84602, USA
Brain Dev 29:389-99. 2007..Results are discussed in terms of pathological connectivity within the temporal lobe as it relates to autism... - Post-traumatic amnesia predicts long-term cerebral atrophy in traumatic brain injuryElisabeth A Wilde
Baylor College of Medicine, Department of Physical Medicine and Rehabilitation, Houston, TX 77030, USA
Brain Inj 20:695-9. 2006..As a guide in assessing patients with TBI, this study determined the probability of developing chronic cerebral atrophy based on PTA duration... - Premorbid intellectual functioning, education, and brain size in traumatic brain injury: an investigation of the cognitive reserve hypothesisShelli R Kesler
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California, USA
Appl Neuropsychol 10:153-62. 2003..The results of this study suggest that larger premorbid brain volume and higher education level may decrease vulnerability to cognitive deficits following TBI, consistent with the notion of a cognitive reserve... - Diffusion tensor imaging in the corpus callosum in children after moderate to severe traumatic brain injuryElisabeth A Wilde
Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Texas, USA
J Neurotrauma 23:1412-26. 2006..DTI may be useful in identifying biomarkers related to DAI and outcome of TBI in children... - Vulnerability of the anterior commissure in moderate to severe pediatric traumatic brain injuryElisabeth A Wilde
Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, 1709 Dryden Road, Houston, TX 77030, USA
J Child Neurol 21:769-76. 2006..This is the first systematic examination of anterior commissure atrophy following traumatic brain injury using in vivo quantitative MRI and diffusion tensor imaging fiber tracking in pediatric subjects... - Neurodevelopmental outcome for extended cold water drowning: a longitudinal case studySusannah Kury Hughes
William Stixrud, Ph D, and Associates, Silver Spring, Maryland 20910, USA
J Int Neuropsychol Soc 8:588-95. 2002..This case demonstrates the need for long-term neuropsychological follow-up of pediatric patients with histories of neurologic injury, as gross neurological examination and MRI and MEG scans may not reveal underlying brain dysfunction... - Alcohol abuse and traumatic brain injury: quantitative magnetic resonance imaging and neuropsychological outcomeElisabeth A Wilde
Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Texas, USA
J Neurotrauma 21:137-47. 2004..Implications of alcohol use, at the time of brain injury, are discussed... - Morphometric MRI findings in the thalamus and brainstem in children after moderate to severe traumatic brain injuryMichael A Fearing
Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA
J Child Neurol 23:729-37. 2008..Reduction in midbrain and thalamic volume is probably a reflection of the secondary effects of diffuse axonal injury and reduction in cortical volume from brain injury... - Regional callosal morphology in autism and macrocephalyShirley Kilian
The Travis Research Institute, Fuller Graduate School of Psychology, Jerry L Pettis Memorial VA Medical Center, Loma Linda, California, USA
Dev Neuropsychol 33:74-99. 2008..These results underscore the importance of considering head size in studies of CC morphology in autism. These findings add to the literature implicating problems of interhemispheric connectivity being present in individuals with autism... - Hippocampus, amygdala, and basal ganglia morphometrics in children after moderate-to-severe traumatic brain injuryElisabeth A Wilde
Baylor College of Medicine, Houston, TX 77030, USA
Dev Med Child Neurol 49:294-9. 2007..In a separate analysis excluding children with focal hippocampal abnormalities (e.g. lesions), group differences in hippocampal volume were still evident, suggesting that hippocampal damage may be diffuse rather than focal... - Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autismJee Eun Lee
Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI, United States
Neurosci Lett 424:127-32. 2007..These results suggest that white matter microstructure in autism is abnormal in these temporal lobe regions, which is consistent with theories of aberrant brain connectivity in autism... - Frontal and temporal morphometric findings on MRI in children after moderate to severe traumatic brain injuryElisabeth A Wilde
Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Texas, USA
J Neurotrauma 22:333-44. 2005..Finally, volumetric measures of preserved frontotemporal tissue were related to functional recovery as measured by the Glasgow Outcome Scale (adapted for children) with greater tissue preservation predicting better recovery... - The "steroid dementia syndrome": a possible model of human glucocorticoid neurotoxicityOwen M Wolkowitz
Department of Psychiatry, Medical Center, University of California, San Francisco, San Francisco, CA, USA
Neurocase 13:189-200. 2007..Although this syndrome is uncommon, it is consistent with evolving theories of the neurotoxic or neuroendangering potential of glucocorticoids in some situations... - Neuropsychological and information processing deficits following mild traumatic brain injuryJane L Mathias
Department of Psychology, University of Adelaide, Adelaide, South Australia
J Int Neuropsychol Soc 10:286-97. 2004.... - Diffusion tensor imaging of the corpus callosum in AutismAndrew L Alexander
Department of Medical Physics, University of Wisconsin, Madison, WI, USA
Neuroimage 34:61-73. 2007..These results suggest that the microstructure of the corpus callosum is affected in autism, which may be related to nonverbal cognitive performance... - Regional atrophy of the corpus callosum in dementiaBradley J Hallam
The Travis Research Institute, Center for Biopsychosocial Research, Fuller Graduate School of Psychology, Pasadena, California, USA
J Int Neuropsychol Soc 14:414-23. 2008..Findings suggest that dementia-related CC atrophy occurs primarily in the anterior and posterior portions... - Can author bias be determined in forensic neuropsychology research published in Archives of Clinical Neuropsychology?Erin D Bigler
Arch Clin Neuropsychol 21:503-8. 2006 - Social outcomes in childhood brain disorder: a heuristic integration of social neuroscience and developmental psychologyKeith Owen Yeates
Department of Pediatrics, The Ohio State University, Center for Biobehavioral Health, Columbus Children s Research Institute, Columbus, OH, USA
Psychol Bull 133:535-56. 2007..It also may engender more precise methods of measuring impairments and disabilities in children with brain disorder and suggest ways to promote their social adaptation... - Measuring medical complexity during inpatient rehabilitation after traumatic brain injuryDavid K Ryser
Division of PM and R and Statistical Data Center, LDS Hospital, 8th Avenue and C, Salt Lake City, UT 84143, USA
Arch Phys Med Rehabil 86:1108-17. 2005.... - Memory and learning in children with 22q11.2 deletion syndrome: evidence for ventral and dorsal stream disruption?Renée R Lajiness-O'Neill
Department of Behavioral Health, Division of Neuropsychology, Henry Ford Health System, Detroit, Michigan 48202, USA
Child Neuropsychol 11:55-71. 2005..2 DS implicates dorsolateral prefrontal regions, both intimating aberrant white matter pathways...