C A Manthous

Summary

Affiliation: Bridgeport Hospital
Country: USA

Publications

  1. ncbi request reprint Informed consent for invasive procedures in a community hospital medical intensive care unit
    Angela DeGirolamo
    Bridgeport Hospital, CT 06610, USA
    Conn Med 68:223-9. 2004
  2. ncbi request reprint Fluid balance and weaning outcomes
    Anupama Upadya
    Pulmonary and Critical Care, Bridgeport Hospital and Yale University School of Medicine, 267 Grant Street, Bridgeport, CT 06610, USA
    Intensive Care Med 31:1643-7. 2005
  3. ncbi request reprint Why not physician-assisted death?
    Constantine A Manthous
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT, USA
    Crit Care Med 37:1206-9. 2009
  4. pmc A practical approach to adult acute respiratory distress syndrome
    Constantine A Manthous
    Yale University School of Medicine, Bridgeport Hospital and Yale University School of Medicine, 267 Grant Street, Bridgeport, CT 06610, USA
    Indian J Crit Care Med 14:196-201. 2010
  5. pmc Cardiac injury in patients with COPD presenting with dyspnea: a pilot study
    Esosa Odigie-Okon
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    Int J Chron Obstruct Pulmon Dis 5:395-9. 2010
  6. doi request reprint Why surgeons can say "no": exploring "unilateral withholding"
    Constantine A Manthous
    Bridgeport Hospital, Bridgeport, CT, USA
    J Hosp Med 7:249-53. 2012
  7. ncbi request reprint Critical care physicians' practices and attitudes and applicable statutes regarding withdrawal of life-sustaining therapies
    Constantine A Manthous
    Department of Internal Medicine, Bridgeport Hospital and Yale University School of Medicine, CT 06610, USA
    Conn Med 69:395-400. 2005
  8. ncbi request reprint Informed consent for medical procedures: local and national practices
    Constantine A Manthous
    Pulmonary and Critical Care Department, Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    Chest 124:1978-84. 2003
  9. doi request reprint Critical care rationing: international comparisons
    Timothy W Evans
    Department of Critical Care, Imperial College School of Medicine, Royal Brompton Hospital, London, England, UK
    Chest 140:1618-24. 2011
  10. doi request reprint Team science and critical care
    Constantine A Manthous
    Bridgeport Hospital and Yale University School of Medicine, 267 Grant Street, Bridgeport, CT 06610, USA
    Am J Respir Crit Care Med 184:17-25. 2011

Collaborators

Detail Information

Publications45

  1. ncbi request reprint Informed consent for invasive procedures in a community hospital medical intensive care unit
    Angela DeGirolamo
    Bridgeport Hospital, CT 06610, USA
    Conn Med 68:223-9. 2004
    ..To describe the informed consent practices in the medical intensive care unit (MICU) of a university-affiliated, community teaching hospital...
  2. ncbi request reprint Fluid balance and weaning outcomes
    Anupama Upadya
    Pulmonary and Critical Care, Bridgeport Hospital and Yale University School of Medicine, 267 Grant Street, Bridgeport, CT 06610, USA
    Intensive Care Med 31:1643-7. 2005
    ..To examine the relationship of fluid balance and weaning outcomes...
  3. ncbi request reprint Why not physician-assisted death?
    Constantine A Manthous
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT, USA
    Crit Care Med 37:1206-9. 2009
    ..This article explores contributions of religion, Western medical mores, law, and emerging concepts of moral neurocognition that may explain our inherent aversion to these ideas...
  4. pmc A practical approach to adult acute respiratory distress syndrome
    Constantine A Manthous
    Yale University School of Medicine, Bridgeport Hospital and Yale University School of Medicine, 267 Grant Street, Bridgeport, CT 06610, USA
    Indian J Crit Care Med 14:196-201. 2010
    ..This article reviews the clinical features and how pathophysiology informs the evidence-based management of ARDS...
  5. pmc Cardiac injury in patients with COPD presenting with dyspnea: a pilot study
    Esosa Odigie-Okon
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    Int J Chron Obstruct Pulmon Dis 5:395-9. 2010
    ..The aim of this pilot study was to test the hypothesis that myocardial ischemia complicates the management of some patients with chest-pain-free chronic obstructive pulmonary disease (COPD) exacerbations...
  6. doi request reprint Why surgeons can say "no": exploring "unilateral withholding"
    Constantine A Manthous
    Bridgeport Hospital, Bridgeport, CT, USA
    J Hosp Med 7:249-53. 2012
    ....
  7. ncbi request reprint Critical care physicians' practices and attitudes and applicable statutes regarding withdrawal of life-sustaining therapies
    Constantine A Manthous
    Department of Internal Medicine, Bridgeport Hospital and Yale University School of Medicine, CT 06610, USA
    Conn Med 69:395-400. 2005
    ..To describe intensivist-educators' practices and opinions regarding the withdrawal of life-sustaining therapies, and to juxtapose these with applicable end-of-life statutes...
  8. ncbi request reprint Informed consent for medical procedures: local and national practices
    Constantine A Manthous
    Pulmonary and Critical Care Department, Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    Chest 124:1978-84. 2003
    ..No studies have assessed whether clinicians obtain informed consent for invasive medical procedures, and there are no explicit national standards to guide the process...
  9. doi request reprint Critical care rationing: international comparisons
    Timothy W Evans
    Department of Critical Care, Imperial College School of Medicine, Royal Brompton Hospital, London, England, UK
    Chest 140:1618-24. 2011
    ....
  10. doi request reprint Team science and critical care
    Constantine A Manthous
    Bridgeport Hospital and Yale University School of Medicine, 267 Grant Street, Bridgeport, CT 06610, USA
    Am J Respir Crit Care Med 184:17-25. 2011
    ..The article highlights how team principles might be used to improve patient care and navigate hospital hierarchies, and concludes with implications for future educational and scientific efforts...
  11. pmc Building effective critical care teams
    Constantine Manthous
    Bridgeport Hospital and Yale University School of Medicine, 267 Grant Street, Bridgeport, CT 06610, USA
    Crit Care 15:307. 2011
    ..Since critical care is a team endeavor, methods to maximize teamwork should be learned and mastered by critical care team members, and especially leaders...
  12. ncbi request reprint Leapfrog and critical care: evidence- and reality-based intensive care for the 21st century
    Constantine A Manthous
    Pulmonary and Critical Care, Bridgeport Hospital, Bridgeport, Connecticut 06610, USA
    Am J Med 116:188-93. 2004
    ....
  13. ncbi request reprint Are living wills useful? In search of a new paradigm
    Constantine A Manthous
    Bridgeport Hospital, Yale University School of Medicine, CT, USA
    Conn Med 67:283-90; discussion 291-2. 2003
    ..Potential solutions for current deficiencies in end-of-life care and decision-making are discussed...
  14. ncbi request reprint Negative fluid balance predicts survival in patients with septic shock: a retrospective pilot study
    F Alsous
    Division of Pulmonary and Critical Care, Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    Chest 117:1749-54. 2000
    ..We hypothesized that patients with septic shock who achieve negative fluid balance (< or =-500 mL) on any day in the first 3 days of management are more likely to survive than those who do not...
  15. ncbi request reprint Summarizing the logistics of liberation from mechanical ventilation
    C A Manthous
    Department of Medicine, Division of Pulmonary and Critical Care, Bridgeport Hospital, Bridgeport, Connecticut 06610, USA
    Respir Care Clin N Am 6:463-8;vi. 2000
    ..This article summarizes the principle themes for this issue of Respiratory Care Clinics of North America and distills the available data to two simple weaning algorithms...
  16. ncbi request reprint Predictors of extubation outcome in patients who have successfully completed a spontaneous breathing trial
    M Khamiees
    Department of Pulmonary and Critical Care, Bridgeport Hospital, Bridgeport, CT 06610, USA
    Chest 120:1262-70. 2001
    ..Also, a majority (89%) of medically ill patients with P:F ratios of 120 to 200 (four of five patients with P:F ratios from 120 to 150), values sometimes used to preclude weaning, were extubated successfully...
  17. ncbi request reprint Thyroid storm presenting as multiple organ dysfunction syndrome
    Y Z Jiang
    Department of Internal Medicine, Bridgeport Hospital, Yale New Haven Health, Bridgeport, CT 06610, USA
    Chest 118:877-9. 2000
    ..This case highlights both the multiple organ systems that can be involved in thyroid storm and the importance of recognizing atypical presentations of thyroid storm...
  18. ncbi request reprint Liberation from mechanical ventilation: what monitoring matters?
    Jonathan M Siner
    Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yale University School of Medicine, P O Box 208057, New Haven, CT 06520 8057, USA
    Crit Care Clin 23:613-38. 2007
    ..We also suggest future study designs that would better inform the process of liberation from the ventilator and endotracheal extubation...
  19. ncbi request reprint Cough peak flows and extubation outcomes
    Mihai Smina
    Pulmonary and Critical Care, Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    Chest 124:262-8. 2003
    ..Semiobjective methods of quantifying cough strength and endotracheal secretions have been demonstrated to predict extubation outcomes of patients who have passed a spontaneous breathing trial (SBT)...
  20. ncbi request reprint Patients' understanding of advance directives and cardiopulmonary resuscitation
    Natalya Thorevska
    Pulmonary and Critical Care, Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    J Crit Care 20:26-34. 2005
    ..To describe understanding of end-of-life issues and compare characteristics of patients with and without advance directives...
  21. ncbi request reprint Outcomes of critically ill patients
    Lisa Tilluckdharry
    Pulmonary and Critical Care, Bridgeport Hospital, CT 06616, USA
    Am J Emerg Med 23:336-9. 2005
    ..We hypothesized that critically ill patients who remain in the ED for more than 24 hours experience worse outcomes and longer lengths of stay than those transferred to the medical intensive care unit (MICU) within 24 hours...
  22. ncbi request reprint Neurologic status, cough, secretions and extubation outcomes
    Adil Salam
    Pulmonary and Critical Care, Bridgeport Hospital and Yale University School of Medicine, 267 Grant Street, Bridgeport, CT 06610, USA
    Intensive Care Med 30:1334-9. 2004
    ..To determine the degree to which neurologic function, cough peak flows and quantity of endotracheal secretions affected the extubation outcomes of patients who had passed a trial of spontaneous breathing (SBT)...
  23. ncbi request reprint Medical professionalism in the new millennium: are there intercultural differences? Brief report and commentary
    Manasi M Shah
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, USA
    Conn Med 73:289-94. 2009
    ..We use the results of this ostensibly "negative" study to comment on the foundations for the hypothesis and logistic difficulty of studying the question...
  24. ncbi request reprint Patient, physician, and family member understanding of living wills
    Anupama Upadya
    Pulmonary and Critical Care, Bridgeport Hospital, Bridgeport, Connecticut 06610, USA
    Am J Respir Crit Care Med 166:1430-5. 2002
    ..These data suggest substantial differences of patient, physician, and family member understanding of living wills. Living wills did not reflect fully patients' expectations of receiving (or not receiving) life-sustaining modalities...
  25. doi request reprint Rapid reversal of acute kidney injury and hospital outcomes: a retrospective cohort study
    Jianmin Tian
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    Am J Kidney Dis 53:974-81. 2009
    ..3 mg/dL or greater in 48 hours, is associated with poor outcomes. The prognosis associated with an increased creatinine level, either on admission or that develops in the hospital (ie, AKI), that rapidly returns to normal is not known...
  26. ncbi request reprint Propofol infusion is associated with a higher rapid shallow breathing index in patients preparing to wean from mechanical ventilation
    Mohammad Khamiees
    Bridgeport Hospital, West Tower 6, 267 Grant Street, Bridgeport, CT 06610, USA
    Respir Care 47:150-3. 2002
    ..To determine whether propofol affects spontaneous breathing patterns in critically ill patients recovering from respiratory failure during initial attempts at liberation from mechanical ventilation...
  27. doi request reprint Age, duration of mechanical ventilation, and outcomes of patients who are critically ill
    Yan Feng
    Bridgeport Hospital, Bridgeport, CT 06610 2870, USA
    Chest 136:759-64. 2009
    ..Age and duration of mechanical ventilation (MV) are strongly associated with mortality and hospital discharge disposition...
  28. doi request reprint Enhanced end-of-life care associated with deploying a rapid response team: a pilot study
    Rodrigo Vazquez
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, Connecticut 06610, USA
    J Hosp Med 4:449-52. 2009
    ..Institution of a rapid response team (RRT) improves patients' quality of death (QOD)...
  29. doi request reprint Outcomes of critically ill patients who received cardiopulmonary resuscitation
    Jianmin Tian
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, Connecticut 06610, USA
    Am J Respir Crit Care Med 182:501-6. 2010
    ..Studies examining survival outcomes after in-hospital cardiopulmonary arrest (CPA) among intensive care unit (ICU) patients requiring medications for hemodynamic support are limited...
  30. ncbi request reprint Promoting a culture of patient safety
    Constantine A Manthous
    Bridgeport Hospital, USA
    Conn Med 72:549-53. 2008
  31. doi request reprint Patients' predilections regarding informed consent for hospital treatments
    Shweta Upadhyay
    Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA
    J Hosp Med 3:6-11. 2008
    ..Respect for patient autonomy is a core principle of American medicine. Informed consent is required for surgical procedures and blood transfusions but not for most medical treatments of hospitalized patients...
  32. ncbi request reprint The effect of arterial blood gas values on extubation decisions
    Adil Salam
    Department of Internal Medicine, Bridgeport Hospital, Yale University, CT 06610, USA
    Respir Care 48:1033-7. 2003
    ..Nonetheless many intensive care units measure ABGs during an SBT to determine, in conjunction with other data, whether the SBT was successful...
  33. pmc Acute kidney injury predicts outcomes of non-critically ill patients
    Fidel Barrantes
    Bridgeport Hospital, Bridgeport, CT 06610, USA
    Mayo Clin Proc 84:410-6. 2009
    ..To evaluate whether acute kidney injury (AKI), defined as an increase in the serum creatinine level of 0.3 mg/dL or more within 48 hours, predicts outcomes of non-critically ill patients...
  34. ncbi request reprint Informed consent for invasive medical procedures from the patient's perspective
    Natalya Thorevska
    Department of Internal Medicine, Bridgeport Hospital, 267 Grant Street, Bridgeport, CT 06610, USA
    Conn Med 68:101-5. 2004
    ..Written informed consent is not obtained uniformly for invasive medical procedures in critically ill patients across America. The general consent-to-treat is used by some institutions in lieu of separate, procedure-by-procedure consent...
  35. ncbi request reprint The 9-11 Commission's invitation to imagine: a pathophysiology-based approach to critical care of nuclear explosion victims
    Constantine A Manthous
    Pulmonary and Critical Care Department, Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT, USA
    Crit Care Med 35:716-23. 2007
    ..Documentation from previous bomb blasts and nuclear accidents is reviewed to assist in forecasting needs of both systems and patients in the event of an NDD in a major metropolitan area...
  36. ncbi request reprint If asked, hospitalized patients will choose whether to receive life-sustaining therapies
    Nelson Nicolasora
    Department of Internal Medicine, Bridgeport Hospital and Yale University School of Medicine, New Haven, Connecticut, USA
    J Hosp Med 1:161-7. 2006
    ..No national policy requires health care providers to discuss with hospitalized patients whether the latter would want cardiopulmonary resuscitation (CPR) or mechanical ventilation (MV) in the event of cardiopulmonary failure...
  37. ncbi request reprint A concussive clinical coincidence
    Constantine A Manthous
    Chest 125:1593-4. 2004
  38. ncbi request reprint Weaning by protocol
    Constantine A Manthous
    Am J Respir Crit Care Med 170:98-9; author reply 99-100. 2004
  39. ncbi request reprint Medical errors and quality of care in Connecticut hospitals. Grappling with the implications of the IOM reports
    Constantine A Manthous
    Conn Med 69:29-32. 2005
  40. ncbi request reprint The sound and the fury
    Constantine A Manthous
    Am J Respir Crit Care Med 173:1414. 2006
  41. ncbi request reprint Beta-agonists for patients with chronic obstructive pulmonary disease and heart disease?
    Hugh Parker
    Am J Emerg Med 26:104-5. 2008
  42. ncbi request reprint An official ATS statement: grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations
    Holger J Schunemann
    Am J Respir Crit Care Med 174:605-14. 2006
  43. ncbi request reprint Toward solving the critical care manpower crisis
    Constantine A Manthous
    Respir Care 51:1224-5. 2006
  44. ncbi request reprint Counterpoint: is it ethical to order "do not resuscitate" without patient consent?
    Constantine A Manthous
    Chest 132:751-4; discussion 754-5. 2007
  45. ncbi request reprint The anarchy of weaning techniques
    Constantine A Manthous
    Chest 121:1738-40. 2002