G G Petsko

Summary

Affiliation: Brandeis University
Country: USA

Publications

  1. pmc The story they missed
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:101. 2008
  2. pmc Transformation
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:117. 2006
  3. pmc Feet in mouth disease
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:105. 2005
  4. pmc A model worth considering?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:121. 2006
  5. pmc How may you help me?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:111. 2005
  6. pmc Foxes and hounds
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:124. 2005
  7. pmc An idea whose time has gone
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:107. 2007
  8. pmc A day in the life of a genome biologist in the not-too-distant future
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:104. 2007
  9. pmc Half right
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:120. 2005
  10. pmc They fought the law and the law won
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:111. 2007

Research Grants

  1. SITE-SPECIFIC MUTAGENESIS OF ISOMERASES
    Gregory Petsko; Fiscal Year: 1993
  2. CRYSTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1999
  3. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2002
  4. Structural Basis for Bridged Bimetallic Enzyme Catalysis
    Gregory Petsko; Fiscal Year: 2005
  5. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2006
  6. SITE-SPECIFIC MUTAGENESIS OF ISOMERASES
    Gregory Petsko; Fiscal Year: 1990
  7. CRYTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1993
  8. CRYSTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1990

Detail Information

Publications78

  1. pmc The story they missed
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:101. 2008
  2. pmc Transformation
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:117. 2006
    ..The Nobel process for science are often somewhat controversial for who they omit. A posthumous Nobel honor could help recognize some neglected heroes...
  3. pmc Feet in mouth disease
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:105. 2005
    ..We can, and should, use the financial resources of our institutions to redress the serious inequities and problems that bright, ambitious women face in the scientific workplace...
  4. pmc A model worth considering?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:121. 2006
    ..A business-science hybrid model for medical research that focuses on collaboration rather than competition seems worth exploring...
  5. pmc How may you help me?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:111. 2005
    ..Most of us have had so many bad experiences with service personnel over the years that we harbor the illusion that doing things for ourselves is faster and better...
  6. pmc Foxes and hounds
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:124. 2005
  7. pmc An idea whose time has gone
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:107. 2007
    ..The $60 million a year in public money that is being spent on the Protein Structure Initiative is enough to fund approximately 100-200 individual investigator-initiated research grants...
  8. pmc A day in the life of a genome biologist in the not-too-distant future
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:104. 2007
    ..A look into the future of a biologist: daily activities governed by presidential mandates and acts...
  9. pmc Half right
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:120. 2005
  10. pmc They fought the law and the law won
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:111. 2007
    ..But there is no way we can ever assess all of the likely consequences...
  11. pmc Funky, not junky
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:104. 2003
    ..In many respects, the most intriguing part of the mouse genome sequence is what it has told us about so-called 'junk' DNA sequences...
  12. pmc Tsunami
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:104. 2005
    ..I believed that genomics was like a tsunami: a force that, when it crested, would change everything...
  13. pmc Everything I need to know about genomics, I learned from Yogi Berra
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:102. 2003
    ..As 2002 draws to a close, I find myself contemplating the future of biology with hope, but also with uncertainty and some apprehension. When I find myself in such a spiritual quandary, I usually turn to a guru...
  14. pmc For the good of the state
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:121. 2003
    ..Recent advances in biology and medicine, from the sequence of the human genome to the cloning of mammals have made many lay people profoundly uneasy about the future of humanity...
  15. pmc Not debatable
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:104. 2008
    ..Science is essential to the economic future and national security. The next US President needs to understand the importance of science, communicate that to the public, and use scientific information properly...
  16. pmc Instructions for repair
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:106. 2006
  17. pmc The ninth wave
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:109. 2006
  18. pmc Do the math
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:119. 2006
    ..Statistics is the one branch of mathematics that everybody should be able to grasp--and all biologists should be required to do so...
  19. ncbi request reprint The highs and lows of scientific conferences
    Gregory A Petsko
    Department of Biochemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, MS 029, 415 South Street, Waltham, MA 02454 9110, USA
    Nat Rev Mol Cell Biol 7:231-4. 2006
    ....
  20. pmc Sweden has the right idea
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:103. 2006
    ....
  21. pmc Senior moments
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:113. 2006
    ..The problem with reaching 'senior faculty' status is the feeling that you have nothing much to contribute except experience, but the recently announced Neanderthal Genome Project might put things into perspective...
  22. pmc Facts and figures
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:111. 2006
  23. pmc The system is broken
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:105. 2006
    ....
  24. pmc The next epidemic
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:108. 2006
  25. pmc What if Watson had said "Apes evolved from man"?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:113. 2007
  26. pmc Jumping the shark
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:101. 2007
    ..In popular-culture, 'jumping the shark' refers to an abandoning of core values in an attempt to appeal to dwindling audiences, a metaphor that might be reasonably be applied to some areas of genomics-based research...
  27. pmc And the second shall be first
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:103. 2007
    ..All too often the first report is sketchy, superficial in its analysis, and prone to error. The second report is often more thoughtful, more useful, and is essential to the scientific process of validation and self-correction...
  28. pmc Wimps? What wimps?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 10:109. 2009
  29. pmc What my genome told me--and what it didn't
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 10:108. 2009
    ..Lessons in personal genome analysis, social networking or health information?..
  30. pmc Too big to succeed?
    Gregory A Petsko
    Genome Biol 10:103. 2009
  31. pmc Having an impact (factor)
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:107. 2008
  32. pmc It is alive
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:106. 2008
    ..We need to familiarize ourselves with the facts of evolution, so that we can mount a spirited defense against creationism and the forces of ignorance...
  33. doi request reprint Biochemistry. How enzymes work
    Dagmar Ringe
    Department of Biochemistry, Brandeis University, Waltham, MA 02454, USA
    Science 320:1428-9. 2008
  34. pmc The new Manichaeans
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:105. 2008
    ..It doesn't serve science well to drift towards a Manichaean view by calling religion 'nonsense'. People of faith may be the natural allies of biologists when it comes to matters of conservation and climate protection...
  35. pmc Lost in translation
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 11:107. 2010
    ..Objections to dividing biomedical research into 'translational' and 'basic' are not just a matter of semantics...
  36. pmc The right to be wrong
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:102. 2008
  37. pmc Medicine man
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:114. 2007
    ..It becomes imperative that our doctors bring to the practice of medicine a true scientific perspective; it may be just as important that those of us doing biomedical research try to learn more of what doctors know...
  38. pmc Strange days
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:110. 2007
  39. pmc My worries are no longer behind me
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:109. 2007
  40. pmc Life is a Ponzi scheme
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 10:101. 2009
    ..Before too long a smaller number of young people will be having to support a larger number of the very old, a typical and unsustainable Ponzi scheme...
  41. pmc It can't happen here--can it?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:105. 2007
    ..Most principal scientific organisations in Western countries have similar ideas about the importance of independence but the independence of American science is being eroded...
  42. pmc Rising in the East
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 11:102. 2010
    ..The genome sequence of the giant panda using next- generation sequencing marks a watershed in genome sequencing - in more ways than one...
  43. pmc H5N1
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:121. 2005
  44. pmc Trinity
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:118. 2005
    ..Our bright young biologists should start thinking now about the ethical issues of what we can do and will be able to do in the future...
  45. pmc Galileo's stepchildren
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:114. 2003
  46. pmc A new recruit for the army of the men of death
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:113. 2003
    ..The army of the men of death, in John Bunyan's memorable phrase, has a new recruit, and fear has a new face: a face wearing a surgical mask...
  47. pmc Ira
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:112. 2003
    ..For a quarter of a century in genetics if you said Ira the chances were you meant Ira Herskowitz. When he died, on April 28 this year, it left a hole in the fields of genetics and genomics the size of the Grand Canyon...
  48. pmc War and peace
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:110. 2003
    ..If the fiftieth anniversary of the double helix teaches us anything it ought to be that great scientific discoveries are almost never made in time of war or directly for the purpose of war...
  49. pmc Judgement call
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:108. 2003
  50. pmc Still no flying cars
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:106. 2003
    ..Why, after less than two centuries of almost incomprehensible technological progress has progress in so many areas seemed to slow almost to a halt...
  51. pmc The guards themselves
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:comment1015. 2002
    ..of biological research are likely, it is to our advantage to preempt government action by devising for ourselves restrictions that we can live with, then the inevitable question becomes: how should these restrictions be administered?..
  52. pmc An Asilomar moment
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1014. 2002
    ....
  53. pmc Fish tale
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:comment1012. 2002
    ..The draft sequence of the genome of the Japanese pufferfish has just been announced and the temptation to humor is great...
  54. pmc No place like Ome
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1010. 2002
    ..Of the two components of the word genome, 'ome' is the more interesting...
  55. pmc Our own petards
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1009. 2002
  56. pmc Grain of truth
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:comment1007. 2002
  57. pmc What's in a name?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1005. 2002
  58. pmc The father of us all
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1004. 2002
  59. pmc A christmas carol
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1001. 2002
  60. pmc The road worrier
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:116. 2003
  61. pmc The usual suspects
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:118. 2003
    ..Any scientist will think twice before reporting any discrepancy or possible theft of biohazardous material to either his or her institution or to the government...
  62. ncbi request reprint Observation of unstable species in enzyme-catalyzed transformations using protein crystallography
    G A Petsko
    Departments of Biochemistry and Chemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Curr Opin Chem Biol 4:89-94. 2000
    ....
  63. pmc The life aquatic
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:116. 2005
    ..If we want to know for sure whether there was, or still is, life on Mars, we have to send people there...
  64. pmc Eighty years ago
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:114. 2005
  65. pmc A matter of life and death
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:109. 2005
    ..Our ability to sustain some of the outward signs of life has rendered obsolete the legal system's definition of what it means to be alive...
  66. pmc Who owns the data?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:107. 2005
    ..About ten years ago, a group of scientists began to argue that it was unfair to ask other scientists to pay to read the results of research that had been publicly funded...
  67. pmc Color blind
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:119. 2004
  68. pmc The emperor's new shibboleth
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:118. 2004
    ..If an idea or result can't be conveyed in plain language, how important can it really be?..
  69. pmc Twilight of a hero
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:116. 2004
    ..The hope for those afflicted with Parkinson's is embryonic stem cell therapy, which depends on research that the Bush administration is doing its best to strangle...
  70. pmc Fame is a bubble, but not for some
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:114. 2004
    ..Brilliant, acerbic, not given to suffer much of anybody gladly, let alone fools, Francis Crick had enormous influence that was due to his style and high scientific standards...
  71. pmc A drop in the bucket
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:112. 2004
    ..With 151 billion dollars, all world-wide AIDS programs could be fully funded for the next 12 years...
  72. pmc Pharmacogenomics arrives
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:108. 2004
  73. pmc The ascent of man?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:106. 2004
    ..Anyone who cares about the moral and social implications of genomics, genetic engineering and biotechnology should read Michael J. Sandel's article, 'The Case Against Perfection', in the April 2004 issue of The Atlantic Monthly...
  74. pmc Doctor Dunsel
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:104. 2004
    ..Repressingly, a robot scientist can generate functional genomic hypothesis and carry out experiments, increasing the working scientist's feelings of redundancy...
  75. pmc Good chemistry
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:103. 2004
    ..It is important to formulate a set of topics--and a Medical College Admissions Test reflecting them--that would leave chemistry departments no choice but to change their teaching...
  76. pmc Bad chemistry
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:102. 2004
    ..Because most basic chemistry students are premedical students, medical schools have enormous influence and could help us start all over again to create undergraduate chemistry education that works...
  77. pmc Live and let diet
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:101. 2003
    ..It used to be that one's generation could be defined simply by the war one fought in. Since the middle of the last century, equally defining are the diets that each generation has been swept up in...
  78. pmc Sleeping dogs
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:120. 2003
    ..The dog genome sequence represents a landmark in the genomics era for a number of reasons...

Research Grants32

  1. SITE-SPECIFIC MUTAGENESIS OF ISOMERASES
    Gregory Petsko; Fiscal Year: 1993
    ..Every mutant will also be examined crystallographically, in complex with the actual substrate glucose...
  2. CRYSTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1999
    ....
  3. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2002
    ..IMPDH catalyzes the rate-determining step in GMT biosynthesis and is a target for immunosuppressive, anticancer, antiviral and antimicrobial drugs. ..
  4. Structural Basis for Bridged Bimetallic Enzyme Catalysis
    Gregory Petsko; Fiscal Year: 2005
    ..abstract_text> ..
  5. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2006
    ..abstract_text> ..
  6. SITE-SPECIFIC MUTAGENESIS OF ISOMERASES
    Gregory Petsko; Fiscal Year: 1990
    ..Finally, mutations will be made at several other positions where the crystallographic results and sequence conservation imply a possible role in either active site architecture or catalysis: Ser 96, Cys 126, Glu 97, and Asn 10...
  7. CRYTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1993
    ..Other members of this family include the regulator for alginate production by Pseudomonas in cystic fibrosis. The remaining four projects aim to determine the structures and mechanism of four enzymes, including alanine racemase...
  8. CRYSTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1990
    ....