G G Petsko

Summary

Affiliation: Brandeis University
Country: USA

Publications

  1. pmc The story they missed
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:101. 2008
  2. pmc Transformation
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:117. 2006
  3. pmc Feet in mouth disease
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:105. 2005
  4. pmc A model worth considering?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:121. 2006
  5. pmc How may you help me?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:111. 2005
  6. pmc Foxes and hounds
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:124. 2005
  7. pmc An idea whose time has gone
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:107. 2007
  8. pmc A day in the life of a genome biologist in the not-too-distant future
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:104. 2007
  9. pmc Half right
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:120. 2005
  10. pmc They fought the law and the law won
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:111. 2007

Research Grants

  1. Structural Basis for Bridged Bimetallic Enzyme Catalysis
    Gregory Petsko; Fiscal Year: 2005
  2. SITE-SPECIFIC MUTAGENESIS OF ISOMERASES
    Gregory Petsko; Fiscal Year: 1990
  3. CRYSTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1999
  4. CRYSTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1990
  5. CRYTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1993
  6. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2006
  7. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2002
  8. SITE-SPECIFIC MUTAGENESIS OF ISOMERASES
    Gregory Petsko; Fiscal Year: 1993

Detail Information

Publications130 found, 100 shown here

  1. pmc The story they missed
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:101. 2008
  2. pmc Transformation
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:117. 2006
    ..The Nobel process for science are often somewhat controversial for who they omit. A posthumous Nobel honor could help recognize some neglected heroes...
  3. pmc Feet in mouth disease
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:105. 2005
    ..We can, and should, use the financial resources of our institutions to redress the serious inequities and problems that bright, ambitious women face in the scientific workplace...
  4. pmc A model worth considering?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 7:121. 2006
    ..A business-science hybrid model for medical research that focuses on collaboration rather than competition seems worth exploring...
  5. pmc How may you help me?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:111. 2005
    ..Most of us have had so many bad experiences with service personnel over the years that we harbor the illusion that doing things for ourselves is faster and better...
  6. pmc Foxes and hounds
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:124. 2005
  7. pmc An idea whose time has gone
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:107. 2007
    ..The $60 million a year in public money that is being spent on the Protein Structure Initiative is enough to fund approximately 100-200 individual investigator-initiated research grants...
  8. pmc A day in the life of a genome biologist in the not-too-distant future
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:104. 2007
    ..A look into the future of a biologist: daily activities governed by presidential mandates and acts...
  9. pmc Half right
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:120. 2005
  10. pmc They fought the law and the law won
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 8:111. 2007
    ..But there is no way we can ever assess all of the likely consequences...
  11. pmc Funky, not junky
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:104. 2003
    ..In many respects, the most intriguing part of the mouse genome sequence is what it has told us about so-called 'junk' DNA sequences...
  12. pmc Tsunami
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:104. 2005
    ..I believed that genomics was like a tsunami: a force that, when it crested, would change everything...
  13. pmc Everything I need to know about genomics, I learned from Yogi Berra
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:102. 2003
    ..As 2002 draws to a close, I find myself contemplating the future of biology with hope, but also with uncertainty and some apprehension. When I find myself in such a spiritual quandary, I usually turn to a guru...
  14. pmc For the good of the state
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:121. 2003
    ..Recent advances in biology and medicine, from the sequence of the human genome to the cloning of mammals have made many lay people profoundly uneasy about the future of humanity...
  15. pmc Not debatable
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:104. 2008
    ..Science is essential to the economic future and national security. The next US President needs to understand the importance of science, communicate that to the public, and use scientific information properly...
  16. pmc Trinity
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 6:118. 2005
    ..Our bright young biologists should start thinking now about the ethical issues of what we can do and will be able to do in the future...
  17. pmc Having an impact (factor)
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:107. 2008
  18. pmc It is alive
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 9:106. 2008
    ..We need to familiarize ourselves with the facts of evolution, so that we can mount a spirited defense against creationism and the forces of ignorance...
  19. pmc What my genome told me--and what it didn't
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 10:108. 2009
    ..Lessons in personal genome analysis, social networking or health information?..
  20. pmc Lost in translation
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 11:107. 2010
    ..Objections to dividing biomedical research into 'translational' and 'basic' are not just a matter of semantics...
  21. pmc Fish tale
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:comment1012. 2002
    ..The draft sequence of the genome of the Japanese pufferfish has just been announced and the temptation to humor is great...
  22. pmc Rising in the East
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 11:102. 2010
    ..The genome sequence of the giant panda using next- generation sequencing marks a watershed in genome sequencing - in more ways than one...
  23. pmc Life is a Ponzi scheme
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 10:101. 2009
    ..Before too long a smaller number of young people will be having to support a larger number of the very old, a typical and unsustainable Ponzi scheme...
  24. pmc Wimps? What wimps?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 10:109. 2009
  25. pmc Too big to succeed?
    Gregory A Petsko
    Genome Biol 10:103. 2009
  26. doi request reprint Biochemistry. How enzymes work
    Dagmar Ringe
    Department of Biochemistry, Brandeis University, Waltham, MA 02454, USA
    Science 320:1428-9. 2008
  27. ncbi request reprint Observation of unstable species in enzyme-catalyzed transformations using protein crystallography
    G A Petsko
    Departments of Biochemistry and Chemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Curr Opin Chem Biol 4:89-94. 2000
    ....
  28. pmc Galileo's stepchildren
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:114. 2003
  29. pmc The road worrier
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:116. 2003
  30. pmc The usual suspects
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:118. 2003
    ..Any scientist will think twice before reporting any discrepancy or possible theft of biohazardous material to either his or her institution or to the government...
  31. pmc Live and let diet
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:101. 2003
    ..It used to be that one's generation could be defined simply by the war one fought in. Since the middle of the last century, equally defining are the diets that each generation has been swept up in...
  32. pmc Bad chemistry
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:102. 2004
    ..Because most basic chemistry students are premedical students, medical schools have enormous influence and could help us start all over again to create undergraduate chemistry education that works...
  33. pmc Good chemistry
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:103. 2004
    ..It is important to formulate a set of topics--and a Medical College Admissions Test reflecting them--that would leave chemistry departments no choice but to change their teaching...
  34. pmc Doctor Dunsel
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:104. 2004
    ..Repressingly, a robot scientist can generate functional genomic hypothesis and carry out experiments, increasing the working scientist's feelings of redundancy...
  35. pmc The ascent of man?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:106. 2004
    ..Anyone who cares about the moral and social implications of genomics, genetic engineering and biotechnology should read Michael J. Sandel's article, 'The Case Against Perfection', in the April 2004 issue of The Atlantic Monthly...
  36. pmc Pharmacogenomics arrives
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:108. 2004
  37. pmc A drop in the bucket
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 5:112. 2004
    ..With 151 billion dollars, all world-wide AIDS programs could be fully funded for the next 12 years...
  38. pmc A new recruit for the army of the men of death
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:113. 2003
    ..The army of the men of death, in John Bunyan's memorable phrase, has a new recruit, and fear has a new face: a face wearing a surgical mask...
  39. pmc Ira
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:112. 2003
    ..For a quarter of a century in genetics if you said Ira the chances were you meant Ira Herskowitz. When he died, on April 28 this year, it left a hole in the fields of genetics and genomics the size of the Grand Canyon...
  40. pmc War and peace
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:110. 2003
    ..If the fiftieth anniversary of the double helix teaches us anything it ought to be that great scientific discoveries are almost never made in time of war or directly for the purpose of war...
  41. pmc A christmas carol
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1001. 2002
  42. pmc The father of us all
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1004. 2002
  43. pmc What's in a name?
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1005. 2002
  44. pmc Grain of truth
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:comment1007. 2002
  45. pmc Our own petards
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1009. 2002
  46. pmc No place like Ome
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1010. 2002
    ..Of the two components of the word genome, 'ome' is the more interesting...
  47. pmc An Asilomar moment
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:COMMENT1014. 2002
    ....
  48. pmc The guards themselves
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 3:comment1015. 2002
    ..of biological research are likely, it is to our advantage to preempt government action by devising for ourselves restrictions that we can live with, then the inevitable question becomes: how should these restrictions be administered?..
  49. pmc Still no flying cars
    Gregory A Petsko
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454 9110, USA
    Genome Biol 4:106. 2003
    ..Why, after less than two centuries of almost incomprehensible technological progress has progress in so many areas seemed to slow almost to a halt...

Research Grants32

  1. Structural Basis for Bridged Bimetallic Enzyme Catalysis
    Gregory Petsko; Fiscal Year: 2005
    ..abstract_text> ..
  2. SITE-SPECIFIC MUTAGENESIS OF ISOMERASES
    Gregory Petsko; Fiscal Year: 1990
    ..Finally, mutations will be made at several other positions where the crystallographic results and sequence conservation imply a possible role in either active site architecture or catalysis: Ser 96, Cys 126, Glu 97, and Asn 10...
  3. CRYSTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1999
    ....
  4. CRYSTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1990
    ....
  5. CRYTALLOGRAPHIC STUDIES OF PROTEIN STRUCTURE/FUNCTION
    Gregory Petsko; Fiscal Year: 1993
    ..Other members of this family include the regulator for alginate production by Pseudomonas in cystic fibrosis. The remaining four projects aim to determine the structures and mechanism of four enzymes, including alanine racemase...
  6. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2006
    ..abstract_text> ..
  7. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2002
    ..IMPDH catalyzes the rate-determining step in GMT biosynthesis and is a target for immunosuppressive, anticancer, antiviral and antimicrobial drugs. ..
  8. SITE-SPECIFIC MUTAGENESIS OF ISOMERASES
    Gregory Petsko; Fiscal Year: 1993
    ..Every mutant will also be examined crystallographically, in complex with the actual substrate glucose...