R S Braithwaite

Summary

Country: USA

Publications

  1. ncbi request reprint Estimating hip fracture morbidity, mortality and costs
    R Scott Braithwaite
    Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Am Geriatr Soc 51:364-70. 2003
  2. pmc Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV
    R Scott Braithwaite
    Section of General Internal Medicine, Yale University School of Medicine and VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Value Health 11:975-9. 2008
  3. pmc A framework for tailoring clinical guidelines to comorbidity at the point of care
    R Scott Braithwaite
    Section of General Internal Medicine, Yale University School of Medicine, West Haven Veterans Affairs Connecticut Healthcare System, VACS 11 ACSL G, 950 Campbell Ave, West Haven, CT 06516, USA
    Arch Intern Med 167:2361-5. 2007
  4. pmc Adherence, virological and immunological outcomes for HIV-infected veterans starting combination antiretroviral therapies
    R Scott Braithwaite
    Section of General Internal Medicine, Department of Medicine, Yale University, 950 Campbell Avenue, West Haven, CT 06516, USA
    AIDS 21:1579-89. 2007
  5. pmc Influence of alternative thresholds for initiating HIV treatment on quality-adjusted life expectancy: a decision model
    R Scott Braithwaite
    Yale University and Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut 06516, USA
    Ann Intern Med 148:178-85. 2008
  6. ncbi request reprint Linking cost sharing to value: an unrivaled yet unrealized public health opportunity
    R Scott Braithwaite
    Yale University School of Medicine and Veterans Affairs Connecticut Healthcare System, New Haven, Connecticut 06516, USA
    Ann Intern Med 146:602-5. 2007
  7. pmc Incorporating quality of evidence into decision analytic modeling
    R Scott Braithwaite
    Yale University School of Medicine and Connecticut Veterans Affairs Healthcare System, New Haven, Connecticut 06516, USA
    Ann Intern Med 146:133-41. 2007
  8. doi request reprint What does the value of modern medicine say about the $50,000 per quality-adjusted life-year decision rule?
    R Scott Braithwaite
    Department of Medicine, Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Med Care 46:349-56. 2008
  9. ncbi request reprint Explaining variability in the relationship between antiretroviral adherence and HIV mutation accumulation
    R S Braithwaite
    Section of General Internal Medicine, Yale University School of Medicine and VA Connecticut Healthcare System, New Haven, CT, USA
    J Antimicrob Chemother 58:1036-43. 2006
  10. pmc Do benefits of earlier antiretroviral treatment initiation outweigh harms for individuals at risk for poor adherence?
    R Scott Braithwaite
    Department of Medicine, Section of General Internal Medicine, Yale University, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut, USA
    Clin Infect Dis 48:822-6. 2009

Detail Information

Publications29

  1. ncbi request reprint Estimating hip fracture morbidity, mortality and costs
    R Scott Braithwaite
    Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Am Geriatr Soc 51:364-70. 2003
    ..To estimate lifetime morbidity, mortality, and costs from hip fracture incorporating the effect of deficits in activities of daily living...
  2. pmc Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV
    R Scott Braithwaite
    Section of General Internal Medicine, Yale University School of Medicine and VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Value Health 11:975-9. 2008
    ..The decrement in utility attributable to side effects from combination antiretroviral therapy (CART) is unknown and likely to influence clinical decisions regarding CART initiation and cost-effectiveness...
  3. pmc A framework for tailoring clinical guidelines to comorbidity at the point of care
    R Scott Braithwaite
    Section of General Internal Medicine, Yale University School of Medicine, West Haven Veterans Affairs Connecticut Healthcare System, VACS 11 ACSL G, 950 Campbell Ave, West Haven, CT 06516, USA
    Arch Intern Med 167:2361-5. 2007
    ..Evidence is accumulating to suggest that clinical guidelines should be modified for patients with comorbidities, yet there is no quantitative and objective approach that considers benefits together with risks...
  4. pmc Adherence, virological and immunological outcomes for HIV-infected veterans starting combination antiretroviral therapies
    R Scott Braithwaite
    Section of General Internal Medicine, Department of Medicine, Yale University, 950 Campbell Avenue, West Haven, CT 06516, USA
    AIDS 21:1579-89. 2007
    ..We aimed to determine adherence, virological, and immunological outcomes one year after starting a first combination antiretroviral therapy (ART) regimen...
  5. pmc Influence of alternative thresholds for initiating HIV treatment on quality-adjusted life expectancy: a decision model
    R Scott Braithwaite
    Yale University and Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut 06516, USA
    Ann Intern Med 148:178-85. 2008
    ..The optimal threshold for initiating HIV treatment is unclear...
  6. ncbi request reprint Linking cost sharing to value: an unrivaled yet unrealized public health opportunity
    R Scott Braithwaite
    Yale University School of Medicine and Veterans Affairs Connecticut Healthcare System, New Haven, Connecticut 06516, USA
    Ann Intern Med 146:602-5. 2007
    ..Systematic efforts to discourage inappropriate cost sharing may improve public health...
  7. pmc Incorporating quality of evidence into decision analytic modeling
    R Scott Braithwaite
    Yale University School of Medicine and Connecticut Veterans Affairs Healthcare System, New Haven, Connecticut 06516, USA
    Ann Intern Med 146:133-41. 2007
    ..We conclude that the results of decision modeling may vary dramatically depending on the stringency of the criteria for selecting evidence to use in the model...
  8. doi request reprint What does the value of modern medicine say about the $50,000 per quality-adjusted life-year decision rule?
    R Scott Braithwaite
    Department of Medicine, Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Med Care 46:349-56. 2008
    ..However, many investigators have questioned the scientific basis of this rule, and it has not been updated...
  9. ncbi request reprint Explaining variability in the relationship between antiretroviral adherence and HIV mutation accumulation
    R S Braithwaite
    Section of General Internal Medicine, Yale University School of Medicine and VA Connecticut Healthcare System, New Haven, CT, USA
    J Antimicrob Chemother 58:1036-43. 2006
    ..Determining the relationship between antiretroviral adherence and resistance accumulation is important for the design and evaluation of adherence interventions. Our objective was to explain heterogeneity observed in this relationship...
  10. pmc Do benefits of earlier antiretroviral treatment initiation outweigh harms for individuals at risk for poor adherence?
    R Scott Braithwaite
    Department of Medicine, Section of General Internal Medicine, Yale University, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut, USA
    Clin Infect Dis 48:822-6. 2009
    ..Earlier treatment increased life expectancy across a wide adherence range (50%-100% of doses taken). Delaying treatment for patients with suboptimal adherence may not always be appropriate...
  11. pmc Is antiretroviral therapy cost-effective in South Africa?
    R Scott Braithwaite
    Department of Medicine, Yale University School of Medicine, Connecticut Veterans Affairs Health Care System, Connecticut, USA
    PLoS Med 3:e60. 2006
  12. pmc The payoff time: a flexible framework to help clinicians decide when patients with comorbid disease are not likely to benefit from practice guidelines
    R Scott Braithwaite
    Department of Internal Medicine, Section of General Internal Medicine, Yale University School of Medicine and VA Connecticut Healthcare System, New Haven, Connecticut, USA
    Med Care 47:610-7. 2009
    ..Practice guidelines rarely consider comorbid illness, and resulting overuse of health services may increase costs without conferring benefit...
  13. pmc Impact of cigarette smoking on mortality in HIV-positive and HIV-negative veterans
    Kristina Crothers
    Department of Internal Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    AIDS Educ Prev 21:40-53. 2009
    ..These findings support the need for improvements in smoking cessation and for studies of mechanisms and diseases underlying increased mortality in smokers with HIV...
  14. pmc Towards a combined prognostic index for survival in HIV infection: the role of 'non-HIV' biomarkers
    Amy C Justice
    Section of General Internal Medicine, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
    HIV Med 11:143-51. 2010
    ..We ask whether 'non-HIV' biomarkers improve differentiation of mortality risk among individuals initiating combination antiretroviral therapy (cART)...
  15. pmc Estimating the impact of alcohol consumption on survival for HIV+ individuals
    R S Braithwaite
    Yale University School of Medicine, West Haven, CT, USA
    AIDS Care 19:459-66. 2007
    ..4 years (From 16.1 years to 9.7 years) with daily consumption. Our results suggest that alcohol is an underappreciated yet modifiable risk factor for poor survival among individuals with HIV...
  16. ncbi request reprint A temporal and dose-response association between alcohol consumption and medication adherence among veterans in care
    R Scott Braithwaite
    West Haven Veterans Administration Medical Center and Yale University School of Medicine, West Haven, Connecticut 06516, USA
    Alcohol Clin Exp Res 29:1190-7. 2005
    ..g., illicit drug use). Our objective was to determine whether there are temporal and dose-response relationships between alcohol consumption and poor adherence...
  17. ncbi request reprint Estimating the rate of accumulating drug resistance mutations in the HIV genome
    R Scott Braithwaite
    Yale University School of Medicine Connecticut VA Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA
    Value Health 10:204-13. 2007
    ..Our objective is to determine the accuracy with which mutation accumulation and other unmeasured parameters could be estimated during model calibration...
  18. ncbi request reprint Estimating the proportion of patients infected with HIV who will die of comorbid diseases
    R Scott Braithwaite
    VAMC New Haven and Yale University School of Medicine, New Haven, Conn, USA
    Am J Med 118:890-8. 2005
    ..Effective antiretroviral therapies have improved the prognosis for patients infected with the human immunodeficiency virus (HIV). We aimed to estimate the likelihood that HIV-infected patients would die of comorbid disease...
  19. ncbi request reprint The cost-effectiveness of strategies to reduce mortality from an intentional release of aerosolized anthrax spores
    R Scott Braithwaite
    Section of General Internal Medicine, Yale University School of Medicine, 950 Campbell Avenue, West Haven, CT 06516, USA
    Med Decis Making 26:182-93. 2006
    ..Intentional exposures to aerosolized Bacillus anthracis spores have caused fatalities...
  20. pmc Adjusting alcohol quantity for mean consumption and intoxication threshold improves prediction of nonadherence in HIV patients and HIV-negative controls
    R Scott Braithwaite
    Department of Medicine, Section of General Internal Medicine, Yale University School of Medicine and Connecticut Veterans Administration Medical Center, West Haven, Connecticut 06516, USA
    Alcohol Clin Exp Res 32:1645-51. 2008
    ..We investigated whether considering an individual's usual drinking quantity or threshold for alcohol-induced cognitive impairment improves the prediction of nonadherence with prescribed medications...
  21. pmc Decreased awareness of current smoking among health care providers of HIV-positive compared to HIV-negative veterans
    Kristina Crothers
    Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
    J Gen Intern Med 22:749-54. 2007
    ..Cigarette smoking is an important risk factor for morbidity and mortality in HIV-positive patients on combination antiretroviral therapy...
  22. ncbi request reprint Intoxication before intercourse and risky sexual behavior in male veterans with and without human immunodeficiency virus infection
    Robert L Cook
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Care 44:S31-6. 2006
    ....
  23. pmc A prospective study of reasons for prolonged hospitalizations on a general medicine teaching service
    Mark R Carey
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Gen Intern Med 20:108-15. 2005
    ..Delays in the care of hospitalized patients may lead to increased length of stay, iatrogenic complications, and costs. No study has characterized delays among general medicine inpatients in the current prospective payment era of care...
  24. pmc Estimating alcohol content of traditional brew in Western Kenya using culturally relevant methods: the case for cost over volume
    Rebecca K Papas
    Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
    AIDS Behav 14:836-44. 2010
    ..Using a computational approach, both methods demonstrated comparable results. We conclude that cost estimation of alcohol content is more culturally relevant and does not differ in accuracy from the international standard...
  25. ncbi request reprint Increasing the efficiency of Monte Carlo cohort simulations with variance reduction techniques
    Steven M Shechter
    Department of Industrial Engineering, University of Pittsburgh, USA
    Med Decis Making 26:550-3. 2006
    ..However, most MC cohort simulations are well suited to the implementation of these techniques. The authors discuss the cost of implementation versus the benefit of reduced replications...
  26. ncbi request reprint The value of medical spending in the United States
    R Scott Braithwaite
    N Engl J Med 355:2492; author reply 2492. 2006
  27. doi request reprint Survival from in-hospital cardiac arrest during nights and weekends
    Mary Ann Peberdy
    Virginia Commonwealth University, Richmond, VA 23298 0204, USA
    JAMA 299:785-92. 2008
    ..Patient physiology and process of care for in-hospital cardiac arrest may be different at night and on weekends because of hospital factors unrelated to patient, event, or location variables...
  28. pmc Vector model of complexity
    R Scott Braithwaite
    J Gen Intern Med 23:895; author reply 896. 2008
  29. ncbi request reprint Improving the utilization of medical crisis teams (Condition C) at an urban tertiary care hospital
    Mohamed I Foraida
    University of Pittsburgh Presbyterian Hospital, Pittsburgh, PA 15213, USA
    J Crit Care 18:87-94. 2003
    ..We aimed to increase the utilization of our medical crisis response team (Condition C) to impact this source of mortality...