J Panksepp

Summary

Affiliation: Bowling Green State University
Country: USA

Publications

  1. doi request reprint The trans-species concept of self and the subcortical-cortical midline system
    Georg Northoff
    Department of Psychiatry, University of Magdeburg, Leipziger Strasse 44, Magdeburg, Germany
    Trends Cogn Sci 12:259-64. 2008
  2. ncbi request reprint Psychology. Beyond a joke: from animal laughter to human joy?
    Jaak Panksepp
    J P Scott Center for Neuroscience, Mind and Behavior, Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Science 308:62-3. 2005
  3. ncbi request reprint Neuroscience. Feeling the pain of social loss
    Jaak Panksepp
    J P Scott Center for Neuroscience, Mind and Behavior, Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Science 302:237-9. 2003
  4. ncbi request reprint Why does separation distress hurt? Comment on MacDonald and Leary (2005)
    Jaak Panksepp
    Bowling Green State University, Bowling Green, OH 43403, USA
    Psychol Bull 131:224-30; author reply 237-40. 2005
  5. ncbi request reprint Regional brain cholecystokinin changes as a function of friendly and aggressive social interactions in rats
    Jaak Panksepp
    J P Scott Center for Neuroscience, Mind and Behavior, Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Brain Res 1025:75-84. 2004
  6. ncbi request reprint "Laughing" rats and the evolutionary antecedents of human joy?
    Jaak Panksepp
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Physiol Behav 79:533-47. 2003
  7. ncbi request reprint Modeling ADHD-type arousal with unilateral frontal cortex damage in rats and beneficial effects of play therapy
    Jaak Panksepp
    Memorial Foundation for Lost Children, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Brain Cogn 52:97-105. 2003
  8. ncbi request reprint At the interface of the affective, behavioral, and cognitive neurosciences: decoding the emotional feelings of the brain
    Jaak Panksepp
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Brain Cogn 52:4-14. 2003
  9. ncbi request reprint Can anthropomorphic analyses of separation cries in other animals inform us about the emotional nature of social loss in humans? Comment on Blumberg and Sokoloff (2001)
    Jaak Panksepp
    Falk Center for Molecular Therapeutics, Department of Biomedical Engineering, Northwestern University, USA
    Psychol Rev 110:376-88; discussion 389-96. 2003
  10. ncbi request reprint Comparative approaches in evolutionary psychology: molecular neuroscience meets the mind
    Jaak Panksepp
    J P Scott Center for Neuroscience, Mind and Behavior and Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Neuro Endocrinol Lett 23:105-15. 2002

Detail Information

Publications47

  1. doi request reprint The trans-species concept of self and the subcortical-cortical midline system
    Georg Northoff
    Department of Psychiatry, University of Magdeburg, Leipziger Strasse 44, Magdeburg, Germany
    Trends Cogn Sci 12:259-64. 2008
    ..Recent data suggest that SRP is operating via a central integrative neural system made up of subcortical-cortical midline structures (SCMSs), that are homologous across mammalian species...
  2. ncbi request reprint Psychology. Beyond a joke: from animal laughter to human joy?
    Jaak Panksepp
    J P Scott Center for Neuroscience, Mind and Behavior, Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Science 308:62-3. 2005
  3. ncbi request reprint Neuroscience. Feeling the pain of social loss
    Jaak Panksepp
    J P Scott Center for Neuroscience, Mind and Behavior, Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Science 302:237-9. 2003
    ..Thus, we now have an explanation for the feeling of physical pain that accompanies emotional loss-whether that be the loss of a loved one, rejection by one's social group, or the distress of separation experienced by young animals...
  4. ncbi request reprint Why does separation distress hurt? Comment on MacDonald and Leary (2005)
    Jaak Panksepp
    Bowling Green State University, Bowling Green, OH 43403, USA
    Psychol Bull 131:224-30; author reply 237-40. 2005
    ..This will require better dialogue between behavioral neuroscientists and the rest of psychology interested in foundational psychoevolutionary issues...
  5. ncbi request reprint Regional brain cholecystokinin changes as a function of friendly and aggressive social interactions in rats
    Jaak Panksepp
    J P Scott Center for Neuroscience, Mind and Behavior, Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Brain Res 1025:75-84. 2004
    ..These data suggest that CCK may play a role in the generation of negative affective states indexed by 22-kHz ultrasonic calls in certain regions of the brain...
  6. ncbi request reprint "Laughing" rats and the evolutionary antecedents of human joy?
    Jaak Panksepp
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Physiol Behav 79:533-47. 2003
    ....
  7. ncbi request reprint Modeling ADHD-type arousal with unilateral frontal cortex damage in rats and beneficial effects of play therapy
    Jaak Panksepp
    Memorial Foundation for Lost Children, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Brain Cogn 52:97-105. 2003
    ..Overall, these results suggest that (1) neonatal frontal lobe lesions can be used as an animal model of the overactivity in ADHD and (2) rough-and-tumble play therapy may be a new useful treatment for ADHD...
  8. ncbi request reprint At the interface of the affective, behavioral, and cognitive neurosciences: decoding the emotional feelings of the brain
    Jaak Panksepp
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Brain Cogn 52:4-14. 2003
    ..The position is advanced that to make progress on understanding the neurobiological nature of affect, we need to utilize experimental strategies different from those that are common in cognitive science...
  9. ncbi request reprint Can anthropomorphic analyses of separation cries in other animals inform us about the emotional nature of social loss in humans? Comment on Blumberg and Sokoloff (2001)
    Jaak Panksepp
    Falk Center for Molecular Therapeutics, Department of Biomedical Engineering, Northwestern University, USA
    Psychol Rev 110:376-88; discussion 389-96. 2003
    ....
  10. ncbi request reprint Comparative approaches in evolutionary psychology: molecular neuroscience meets the mind
    Jaak Panksepp
    J P Scott Center for Neuroscience, Mind and Behavior and Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Neuro Endocrinol Lett 23:105-15. 2002
    ..Claims regarding evolved, uniquely human, psychological constructs should be constrained by the rigorous evidentiary standards that are routine in other sciences...
  11. ncbi request reprint 50-kHz chirping (laughter?) in response to conditioned and unconditioned tickle-induced reward in rats: effects of social housing and genetic variables
    J Panksepp
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Behav Brain Res 115:25-38. 2000
    ..Overall, these results suggest that tickle evoked 50-kHz USVs may be a useful behavioral marker of positive social affect in rats. Difficulties with such concepts are also discussed...
  12. ncbi request reprint The role of brain emotional systems in addictions: a neuro-evolutionary perspective and new 'self-report' animal model
    Jaak Panksepp
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior Bowling Green State University, OH 43403, USA
    Addiction 97:459-69. 2002
    ..We conclude by discussing some therapeutic and social implications of examining drug addiction processes with multiple emotional brain systems in mind...
  13. ncbi request reprint Tickling induces reward in adolescent rats
    J Burgdorf
    Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Physiol Behav 72:167-73. 2001
    ..These findings suggest that tickling can be used to induce positive social affect in rodents, and that it is modulated by endogenous opioids...
  14. doi request reprint Uncovering the molecular basis of positive affect using rough-and-tumble play in rats: a role for insulin-like growth factor I
    J Burgdorf
    Falk Center for Molecular Therapeutics, Department of Biomedical Engineering, McCormick School of Engineering and Applied Sciences, Northwestern University, Evanston, IL 60201, USA
    Neuroscience 168:769-77. 2010
    ..These results show that IGFI plays a functional role in the generation of positive affective states and that IGFI-dependent signaling is a potential therapeutic target for the treatment of depression and anxiety...
  15. doi request reprint Selective breeding for 50 kHz ultrasonic vocalization emission produces alterations in the ontogeny and regulation of rough-and-tumble play
    E S Webber
    Bowling Green State University, JP Scott Center for Neuroscience Mind and Behavior, Bowling Green, OH 43403, United States
    Behav Brain Res 229:138-44. 2012
    ..These findings suggest that selection for positive or negative social-emotional phenotypes may also segregate genes that control emotional learning abilities in unanticipated ways...
  16. pmc Positive emotional learning is regulated in the medial prefrontal cortex by GluN2B-containing NMDA receptors
    J Burgdorf
    Falk Center for Molecular Therapeutics, Department of Biomedical Engineering, Northwestern University, Evanston, IL 60201, USA
    Neuroscience 192:515-23. 2011
    ..1-10 μg/side) significantly increased rates of positive emotional learning. Thus GluN2B-containing NMDARs may be involved in positive emotional learning in the MPFC by similar mechanisms as spatial/temporal learning in the hippocampus...
  17. doi request reprint Rats selectively bred for low levels of 50 kHz ultrasonic vocalizations exhibit alterations in early social motivation
    K M Harmon
    Department of Psychology, Bowling Green State University, Bowing Green, OH 43403, USA
    Dev Psychobiol 50:322-31. 2008
    ....
  18. pmc Social defeat, a paradigm of depression in rats that elicits 22-kHz vocalizations, preferentially activates the cholinergic signaling pathway in the periaqueductal gray
    Roger A Kroes
    Department of Biomedical Engineering, Falk Center for Molecular Therapeutics, McCormick School of Engineering, Northwestern University, 1801 Maple Ave Suite 4300, Evanston, IL 60201, USA
    Behav Brain Res 182:290-300. 2007
    ..These data suggest that cholinergic transmission in the PAG is involved in the generation of 22-kHz USVs and provide potential therapeutic targets for the treatment of affective disorders...
  19. doi request reprint Ultrasonic vocalizations of rats (Rattus norvegicus) during mating, play, and aggression: Behavioral concomitants, relationship to reward, and self-administration of playback
    Jeffrey Burgdorf
    Falk Center for Molecular Therapeutics, Department of Biomedical Engineering, Northwestern University
    J Comp Psychol 122:357-67. 2008
    ..Playback of flat 50-kHz calls or tape hiss was neutral. These results suggest that frequency modulated 50-kHz calls index a positively valenced, appetitive, social-emotional state in rats...
  20. ncbi request reprint The neurobiology of positive emotions
    Jeffrey Burgdorf
    Department of Psychology, J P Scott Center for Neuroscience Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Neurosci Biobehav Rev 30:173-87. 2006
    ..e. sensory pleasure) states, and various neuropeptides mediate homeostatic satisfactions...
  21. ncbi request reprint Modeling depression: social dominance-submission gene expression patterns in rat neocortex
    R A Kroes
    Falk Center for Molecular Therapeutics, Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, 1801 Maple Avenue, Suite 4300, Evanston, IL 60201, USA
    Neuroscience 137:37-49. 2006
    ....
  22. doi request reprint The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats
    Jeffrey Burgdorf
    Department of Biomedical Engineering, Falk Center for Molecular Therapeutics, Northwestern University, 1801 Maple Ave, Suite 4300, Evanston, IL 60201, USA
    Dev Psychobiol 51:34-46. 2009
    ..As such these animals could provide novel insights into the neurobiology of emotion...
  23. ncbi request reprint Regional brain cholecystokinin changes as a function of rough-and-tumble play behavior in adolescent rats
    Jeffrey Burgdorf
    J P Scott Center for Neuroscience, Mind and Behavior, Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Peptides 27:172-7. 2006
    ..57), and suggest that the lower CCK levels may reflect the more positive valenced aspects of play. The data indicate that CCK utilization in the brain is dynamically responsive to rough-and-tumble play...
  24. ncbi request reprint Expression of c-fos gene activation during rough and tumble play in juvenile rats
    Nakia S Gordon
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Brain Res Bull 57:651-9. 2002
    ....
  25. ncbi request reprint Socially-induced brain 'fertilization': play promotes brain derived neurotrophic factor transcription in the amygdala and dorsolateral frontal cortex in juvenile rats
    Nakia S Gordon
    Department of Psychology, J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA
    Neurosci Lett 341:17-20. 2003
    ..These effects suggest that play may help program higher brain regions involved in emotional behaviors...
  26. ncbi request reprint Play behavior in rats pretreated with scopolamine: increased play solicitation by the non-injected partner
    Terrence Deak
    Behavioral Neuroscience Program, Department of Psychology, State University of New York at Binghamton, Vestal Parkway East, Binghamton, NY 13902 6000, USA
    Physiol Behav 87:120-5. 2006
    ....
  27. ncbi request reprint The role of emotional systems in addiction: a neuroethological perspective
    Jaak Panksepp
    Bowling Green State University, USA
    Nebr Symp Motiv 50:85-126. 2004
  28. ncbi request reprint Breeding for 50-kHz positive affective vocalization in rats
    Jeffrey Burgdorf
    J P Scott Center for Neuroscience, Mind and Behavior Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Behav Genet 35:67-72. 2005
    ..These results extend our previous findings that laboratory rats could be bred for differential rates of sonographically verified 50-kHz USVs...
  29. ncbi request reprint Fetal and neonatal exposure to trimethylolpropane phosphate alters rat social behavior and emotional responsivity
    M Y Bekkedal
    Department of Psychology, Bowling Green State University, OH, USA
    Neurotoxicol Teratol 21:435-43. 1999
    ..Due to the observed sex differences. it is hypothesized that the action of TMPP may involve a change in the hormonal systems that control the differentiation of related sex-typical behaviors...
  30. ncbi request reprint Oxytocin mediates acquisition of maternally associated odor preferences in preweanling rat pups
    E Nelson
    Department of Psychology, Bowling Green State University, USA
    Behav Neurosci 110:583-92. 1996
    ..Results are discussed in terms of a possible reward-satiety role for oxytocin in the infant-mother context...
  31. ncbi request reprint Affective consciousness: Core emotional feelings in animals and humans
    Jaak Panksepp
    Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
    Conscious Cogn 14:30-80. 2005
    ..In other words, the information-processing brain functions, critical for cognitive consciousness, are harder to study in other animals than the more homologous emotional/motivational affective state functions of the brain...
  32. pmc Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective
    Antonio Alcaro
    Department of Biological Sciences and J P Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Life Science Building, Bowling Green, OH 43403, USA
    Brain Res Rev 56:283-321. 2007
    ..The implications of such a view for understanding addiction are considered, with particular emphasis on factors predisposing individuals to develop compulsive drug seeking behaviors...
  33. ncbi request reprint Neurobiology of 50-kHz ultrasonic vocalizations in rats: electrode mapping, lesion, and pharmacology studies
    Jeffrey Burgdorf
    Falk Center for Molecular Therapeutics, Department of Biomedical Engineering, Northwestern University, Evanston, IL 60201, USA
    Behav Brain Res 182:274-83. 2007
    ....
  34. doi request reprint Effects of a single and repeated morphine treatment on conditioned and unconditioned behavioral sensitization in Crayfish
    Thomas I Nathaniel
    J P Scott Center for Neuroscience, Mind and Behavior, and Department of Biological Sciences Bowling Green State University, Bowling Green, OH 43403, USA
    Behav Brain Res 207:310-20. 2010
    ..Behavioral sensitization studies in Crayfish thus contribute an evolutionary, comparative context to our understanding of the natural variation of reward as an important life-sustaining process...
  35. pmc Validation of a novel social investigation task that may dissociate social motivation from exploratory activity
    Terrence Deak
    Behavioral Neuroscience Program, Department of Psychology, State University of New York at Binghamton, Vestal Parkway East, Binghamton, NY 13902 6000, USA
    Behav Brain Res 199:326-33. 2009
    ..Importantly, the task is bi-directionally sensitive to subject characteristics (i.e., sex), drug manipulations which modulate social motivation, and environmental manipulations...
  36. ncbi request reprint Ultrasonic vocalizations as indices of affective states in rats
    Brian Knutson
    Department of Psychology, Stanford University, California 94305, USA
    Psychol Bull 128:961-77. 2002
    ..This hypothesis has theoretical implications for understanding the brain circuitry underlying mammalian affective states and clinical applicability for modeling hedonic properties of different psychotropic compounds...
  37. pmc Drug-seeking behavior in an invertebrate system: evidence of morphine-induced reward, extinction and reinstatement in crayfish
    Thomas I Nathaniel
    J P Scott Center for Neuroscience, Mind and Behavior and Department of Biological Sciences Bowling Green State University, USA
    Behav Brain Res 197:331-8. 2009
    ..Together with other recent studies, this work demonstrates the advantage of using crayfish as an invertebrate animal model to investigate the basic biological processes that underline exposure to mammalian drugs of abuse...
  38. ncbi request reprint High frequency repetitive transcranial magnetic over the medial cerebellum induces a shift in the prefrontal electroencephalography gamma spectrum: a pilot study in humans
    Dennis J L G Schutter
    Affective Neuroscience Section, Helmholtz Research Institute, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
    Neurosci Lett 336:73-6. 2003
    ..Moreover elevations in mood and alertness were reported again after medial cerebellar stimulation only. Taken together, these data confirm and further specify the assumed cerebellar modulation of PFC activity and affect...
  39. ncbi request reprint Self-referential processing in our brain--a meta-analysis of imaging studies on the self
    Georg Northoff
    Department of Neurology, Harvard University, Cambridge, MA 02138, USA
    Neuroimage 31:440-57. 2006
    ..We conclude that self-referential processing in CMS constitutes the core of our self and is critical for elaborating experiential feelings of self, uniting several distinct concepts evident in current neuroscience...
  40. ncbi request reprint Emotional endophenotypes in evolutionary psychiatry
    Jaak Panksepp
    Center for the Study of Animal Well being, College of Veterinary Medicine VCAPP, Washington State University, Pullman, Washington, USA
    Prog Neuropsychopharmacol Biol Psychiatry 30:774-84. 2006
    ....
  41. ncbi request reprint Neuroevolutionary sources of laughter and social joy: modeling primal human laughter in laboratory rats
    Jaak Panksepp
    Department of VCAPP, College of Veterinary Medicine, P O Box 646520, Washington State University, Pullman, WA 99164, USA
    Behav Brain Res 182:231-44. 2007
    ..It is proposed that further study of this phenomenon may provide a theoretical as well as empirical handle on the sources of social joy within the mammalian brain...
  42. ncbi request reprint Prior morphine experience induces long-term increases in social interest and in appetitive behavior for natural reward
    Christine Nocjar
    Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH 44106, United States
    Behav Brain Res 181:191-9. 2007
    ....
  43. ncbi request reprint Opioids: from physical pain to the pain of social isolation
    Dan J Stein
    Department of Mental Health and Psychiatry, University of Cape Town, South Africa
    CNS Spectr 12:669-70, 672-4. 2007
    ..A role for interventions with opioid agents in depression and anxiety disorders has been suggested...
  44. ncbi request reprint Brain regional neuropeptide changes resulting from social defeat
    Jaak Panksepp
    Department of Veterinary Comparative Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA
    Behav Neurosci 121:1364-71. 2007
    ..CRF was diminished in the hippocampus. The results highlight more robust CCK modulation by social defeat as compared with 3 other neuropeptide systems involved in brain emotional regulation...
  45. pmc Does any aspect of mind survive brain damage that typically leads to a persistent vegetative state? Ethical considerations
    Jaak Panksepp
    Department of VCAPP, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA
    Philos Ethics Humanit Med 2:32. 2007
    ....
  46. ncbi request reprint Chronic intermittent amphetamine pretreatment enhances future appetitive behavior for drug- and natural-reward: interaction with environmental variables
    Christine Nocjar
    Department of Psychiatry, Louis Stokes Cleveland VA Medical Center, 10000 Brecksville Road, Brecksville, OH 44141, USA
    Behav Brain Res 128:189-203. 2002
    ..Thus, the environment surrounding chronic psychostimulant drug experience can greatly affect subsequent reward appetite, but the sensitized expression may be individually determined...
  47. ncbi request reprint Toward a science of ultimate concern
    Jaak Panksepp
    Conscious Cogn 14:22-9. 2005