Anja Forche

Summary

Affiliation: Bowdoin College
Country: USA

Publications

  1. pmc Efficient and rapid identification of Candida albicans allelic status using SNP-RFLP
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA
    FEMS Yeast Res 9:1061-9. 2009
  2. pmc Evolution in Candida albicans populations during a single passage through a mouse host
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Genetics 182:799-811. 2009
  3. pmc Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies
    Melanie Legrand
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America
    PLoS Genet 4:e1. 2008
  4. doi An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
    Anna Selmecki
    Department of Genetics, Cell and Development, University of Minnesota, Minneapolis, MN 55305, USA
    Mol Microbiol 68:624-41. 2008
  5. pmc Aneuploid chromosomes are highly unstable during DNA transformation of Candida albicans
    Kelly Bouchonville
    University of Minnesota, GCD, 6 160 Jackson Hall, 321 Church St SE, Minneapolis, MN 55455, USA
    Eukaryot Cell 8:1554-66. 2009
  6. pmc Demonstration of loss of heterozygosity by single-nucleotide polymorphism microarray analysis and alterations in strain morphology in Candida albicans strains during infection
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, 6 160 Jackson Hall, 321 Church St SE, Minneapolis, MN 55455, USA
    Eukaryot Cell 4:156-65. 2005
  7. pmc The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America
    PLoS Biol 6:e110. 2008
  8. pmc The 'obligate diploid' Candida albicans forms mating-competent haploids
    Meleah A Hickman
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Nature 494:55-9. 2013
  9. pmc Analysis of protein function in clinical C. albicans isolates
    Maryam Gerami-Nejad
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
    Yeast 29:303-9. 2012
  10. pmc Aneuploidy and isochromosome formation in drug-resistant Candida albicans
    Anna Selmecki
    Department of Genetics, Cell Biology, and Development, University of Minnesota, 6 160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Science 313:367-70. 2006

Collaborators

  • Judith Berman
  • Yue Wang
  • Beatrice B Magee
  • Anna Selmecki
  • Melanie Legrand
  • Maryam Gerami-Nejad
  • Meleah A Hickman
  • Kelly Bouchonville
  • Darren Abbey
  • Benjamin D Harrison
  • Guisheng Zeng
  • Richard J Bennett
  • Matthew P Hirakawa
  • Ching Hua Su
  • Mark McClellan
  • Karen E S Tang
  • Christine Chan
  • Carsten Paulson
  • David T Kirkpatrick
  • Paul Lephart
  • T Walsh
  • Frank Michael C Mueller
  • P T Magee

Detail Information

Publications13

  1. pmc Efficient and rapid identification of Candida albicans allelic status using SNP-RFLP
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA
    FEMS Yeast Res 9:1061-9. 2009
    ..While less comprehensive than array-based approaches, we propose SNP-RFLP as an inexpensive, rapid, and reliable method to screen strains of interest for possible genome changes...
  2. pmc Evolution in Candida albicans populations during a single passage through a mouse host
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Genetics 182:799-811. 2009
    ..Results suggest that the dynamics of population growth and genomewide rearrangement contribute to the maintenance of a commensal and opportunistic life history of C. albicans...
  3. pmc Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies
    Melanie Legrand
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America
    PLoS Genet 4:e1. 2008
    ..Therefore, induced aneuploidies can be used to generate HapMaps, which are essential for analyzing genome alterations and mitotic recombination events in this clonal organism...
  4. doi An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
    Anna Selmecki
    Department of Genetics, Cell and Development, University of Minnesota, Minneapolis, MN 55305, USA
    Mol Microbiol 68:624-41. 2008
    ..Thus, the major mechanism by which i(5L) formation causes increased azole resistance is by amplifying two genes: ERG11 and TAC1...
  5. pmc Aneuploid chromosomes are highly unstable during DNA transformation of Candida albicans
    Kelly Bouchonville
    University of Minnesota, GCD, 6 160 Jackson Hall, 321 Church St SE, Minneapolis, MN 55455, USA
    Eukaryot Cell 8:1554-66. 2009
    ..Thus, aneuploid strains are particularly prone to undergo changes in chromosome number during the stresses of DNA transformation protocols...
  6. pmc Demonstration of loss of heterozygosity by single-nucleotide polymorphism microarray analysis and alterations in strain morphology in Candida albicans strains during infection
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, 6 160 Jackson Hall, 321 Church St SE, Minneapolis, MN 55455, USA
    Eukaryot Cell 4:156-65. 2005
    ....
  7. pmc The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America
    PLoS Biol 6:e110. 2008
    ..albicans. We discuss, in light of the long association of C. albicans with warm-blooded animals, the potential advantages of a parasexual cycle over a conventional sexual cycle...
  8. pmc The 'obligate diploid' Candida albicans forms mating-competent haploids
    Meleah A Hickman
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Nature 494:55-9. 2013
    ..Finally, we constructed stable haploid strains with multiple auxotrophies that will facilitate molecular and genetic analyses of this important pathogen...
  9. pmc Analysis of protein function in clinical C. albicans isolates
    Maryam Gerami-Nejad
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
    Yeast 29:303-9. 2012
    ..Together, these vectors provide a useful set of genetic tools for studying diverse aspects of gene function in both clinical and laboratory strains of C. albicans...
  10. pmc Aneuploidy and isochromosome formation in drug-resistant Candida albicans
    Anna Selmecki
    Department of Genetics, Cell Biology, and Development, University of Minnesota, 6 160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Science 313:367-70. 2006
    ....
  11. pmc Genomic plasticity of the human fungal pathogen Candida albicans
    Anna Selmecki
    Department of Genetics, Cell Biology, and Development, 6 160 Jackson Hall, University of Minnesota, Minneapolis, MN 55455, USA
    Eukaryot Cell 9:991-1008. 2010
    ..albicans may provide important insights into how these processes occur in higher-eukaryotic cells exposed to stresses such as anticancer drugs...
  12. pmc Genome-wide single-nucleotide polymorphism map for Candida albicans
    Anja Forche
    Department Genetics, Cell Biology, Development, University of Minnesota, Minneapolis, MN 55455, USA
    Eukaryot Cell 3:705-14. 2004
    ..albicans that are frequently used for gene manipulation experiments. The SNP map will be useful for understanding the role of heterozygosity and genome rearrangement in the response of C. albicans to host environments...
  13. ncbi Homozygosity at the MTL locus in clinical strains of Candida albicans: karyotypic rearrangements and tetraploid formation
    Melanie Legrand
    Department of Genetics, Cell Biology, and Development, University of Minnesota, 321 Church St SE, Minneapolis, MN 55455, USA
    Mol Microbiol 52:1451-62. 2004
    ..Furthermore, as clinical strains can mate and form tetraploids, mating and marker exchange are likely to be a significant part of the life cycle of C. albicans in vivo...