Yuqing Zhang

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..Population trends in patterns of alcohol use are important data for policymakers but are generally based on repeated cross-sectional surveys...

..To study the relationship between cherry intake and the risk of recurrent gout attacks among individuals with gout...

..To examine and quantify the relation between purine intake and the risk of recurrent gout attacks among gout patients...

..Case descriptions suggest IBS patients are more likely to have other disorders, including migraine, fibromyalgia, and depression. We sought to examine the prevalence of these conditions in cohorts of people with and without IBS...

..The aim of this survey was to estimate the burden of disability, analgesia, and health services use associated with knee pain in rural China...

..033). No association was found between bone mass and rectal cancer. The findings suggest that women with higher bone mass, perhaps reflecting greater cumulative estrogen exposure, have a decreased risk of colon cancer...

..To evaluate the feasibility of conducting an online case-crossover study of triggers for recurrent disease flares...

..Alcohol consumption has long been considered a trigger for recurrent gout attacks; however, this hypothesis has not been formally tested...

..Many studies have evaluated the association between vitamin and mineral supplement use and the risk of prostate cancer, with inconclusive results...

..Modifying these factors may reduce the risk of OA and prevent subsequent pain and disability...

..We describe commonly used measures of knee pain in longitudinal studies and review various analytic approaches to evaluating the effect of a risk factor on each type of pain measure...

..In conclusion, long-term regular use of NSAIDs was associated with decreased risk of breast cancer. The type of NSAID used or the hormone receptor status of the tumor did not modify the effect...

..The findings suggest that increased exposure to estrogen during the reproductive years may play a role in the development of pancreatic cancer in women. Further studies are needed to confirm the findings...

..Risk factors for non-Hodgkin lymphoma (NHL) are largely unknown. Several studies have examined the relation of non-steroidal anti-inflammatory drug (NSAID) use to the risk of NHL, with inconsistent results...

..This study was undertaken to determine whether pain resolution is accompanied by diminution of lesions in patients with knee OA...

..To examine the relation of bone mass-a potential biologic marker for cumulative exposure to androgens, insulin-like growth factors, and calcium intake-to subsequent development of prostate cancer...

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..001). These results suggest that bone mineral density in the elderly is associated with verbal memory impairment. The mechanisms underlying this relation are not understood, but cumulative exposure to estrogen may play a role...

..The goals of this study were to estimate the prevalence of hand OA among elderly Chinese in Beijing, and to compare it with that among elderly whites in the United States...

..We examined the relationship between unilateral versus bilateral pain with low physical functioning at baseline and 30 months while accounting for knee pain severity...

..53, 1.00; p(trend) = 0.03). In contrast, no association was present in men (highest vs. lowest quartile of metacarpal cortical area: hazard ratio = 1.14, 95% confidence interval: 0.84, 1.56; p(trend) = 0.55)...

..We conducted a population-based survey among elderly Chinese individuals living in Beijing, to explore whether chopsticks use is associated with prevalent hand OA...

..To evaluate the long-term effect of recreational exercise on the development of knee osteoarthritis (OA) in a community-based cohort of older adults, many of whom were overweight or obese...

..Therefore, we hypothesized that a higher M:L BMD ratio would be associated with medial bone marrow lesions, and that lower ratios would be associated with lateral bone marrow lesions...

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..To examine the relation of radiographic features of osteoarthritis to knee pain in people with knees discordant for knee pain in two cohorts...

..It may also play an important role in knee symptoms. This study highlights the importance of mechanical forces in the determination of OA and knee symptoms...

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..Given the current lack of understanding of the etiology of chondrocalcinosis, further epidemiologic studies of the impact of genetic and environmental factors on occurrence of chondrocalcinosis are indicated...

..Reports on the association between alcohol consumption and the risk of lung cancer have been inconsistent. The purpose of this study was to assess this association in a cohort study...

..To introduce a comprehensive and reliable scoring system for the assessment of whole-knee joint synovitis based on contrast-enhanced (CE) MRI...

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..We propose a new approach using multiple views and compartments that is likely to be more sensitive to change and reveals progression throughout the knee...

..To assess several putative risk factors, including thiazide and loop diuretics use, thought to trigger recurrent gout attacks...

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..We evaluated the relationship of change in radiographic OA to the incidence of severe functional limitation...

..One of the mechanical influences on cartilage loss is limb alignment. We explored the structural factors associated with malalignment in subjects with symptomatic OA...

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..A recent surge in knee replacements is assumed to be due to aging and increased obesity of the U.S. population...

..Bone mineral density (BMD) is a potential surrogate marker for cumulative estrogen exposure and has been associated with cognitive performance and risk of cognitive deterioration...

..Incidence was 24% in women and 10% in men. Few factors in middle-aged persons, except prevalent (moderate) fracture and alcohol consumption (in men), predicted long-term incidence of vertebral fracture...

..These questions were tested using longitudinal magnetic resonance imaging (MRI) data in a natural history study of symptomatic knee osteoarthritis (OA)...

..These results suggest that OC use is associated with an increased risk of breast cancer diagnosed in recent years...

..To evaluate the patterns and determinants of medication use during recurrent gout attacks...

..To evaluate the person-level impact of weight loss on serum urate levels among men with a high cardiovascular risk profile...

..We evaluated the relationship between change in a diuretic prescription (new prescription or increased dose) and the occurrence of documented falls among nursing home residents...

..Additional studies will be required to establish the normal and abnormal ranges of patellar alignment indices and their longitudinal relation to patello-femoral OA...

..To assess risk of cartilage loss in the tibiofemoral joint in relation to baseline damage severity, and to analyse the association of nearby pathologic findings on the risk of subsequent cartilage loss...

..This study was undertaken to examine whether particular abnormalities predisposing to hip OA occur more frequently in whites and whether these differences in hip shape account for differences in the prevalence of OA...

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..BMI accounted for 9.7% of the variability of walking while knee pain accounted for 2.9%. BMI was associated with walking independent of knee pain...

..Men and women differ in the factors associated with musculoskeletal pain in older ages. Further research is needed to understand sex differences in musculoskeletal pain the older population...

..Previous results have been conflicting, showing increases, decreases, or no effect of alcohol on risk of calcified plaque...

..To assess baseline factors that may predict fast tibiofemoral cartilage loss over a 30-month period...

..We investigated the influence of cimetidine use on the risk of breast cancer in our hospital-based case control surveillance study...

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..This study evaluated whether the effect of body weight on progression of knee osteoarthritis (OA) differs depending on the degree of limb malalignment...

..To describe the association between serum 25-hydroxyvitamin D (25[OH]D) level and bone mineral density (BMD) in persons with primary knee osteoarthritis (OA)...

..73, 0.72, 0.72, 0.70 g/cm2, lowest to highest quartile, P for trend=0.02. Cholesterol levels in women and men from young adulthood to middle age years do not appear to have long-term clinical implications for osteoporosis later in life...

..To examine the role of anti-tumor necrosis factor (anti-TNF) agents in predicting work disability in subjects with rheumatoid arthritis (RA)...

..Despite inconsistencies in the data, these results strengthen the evidence that cigarette smoking may play a role in the development of mucinous ovarian cancer but not ovarian cancer of other cell types...

..This study examined the effect of birth cohort on incidence rates of hip fracture among women and men in the Framingham Study...

..To estimate national total knee arthroplasty (TKA) rates by economic factors, and the extent to which differences in insurance coverage, income, and assets contribute to racial and ethnic disparities in TKA use...

..We conclude that the metabolic syndrome and most of its components are associated with a higher prevalence of calcified atherosclerotic plaque in the coronary arteries and abdominal aorta in white and African-American men and women...

..Here, we examined whether SUA is associated with CAC, using the same study sample and methods as for our previous carotid atherosclerosis study...

..Genes in these regions may regulate bone geometry via effects on body size. Identification and subsequent characterization of loci for bone geometry can further elucidate the genetic contributions to bone's resistance to stress...

..To determine the independent associations of antihypertensive drugs with the risk of incident gout among people with hypertension...

..To evaluate the effect of nine disabling medical conditions upon recovery from functional limitations by elders...

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..While genetic factors are major determinants of high-density lipoprotein cholesterol (HDL-C), environmental factors also play a role. The latter include 3 modifiable lifestyle factors: alcohol consumption, physical activity, and smoking...

..We also discuss recently identified methodologic challenges to the study of knee osteoarthritis, particularly osteoarthritis progression...

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..We assessed whether bone loss is completely reversible after cessation of IPC use, whether different IPCs have different effects and whether effects vary by age at first use...

..0; 95% CI, 0.9-1.1.) Misclassification of IBS would have biased the rate ratio toward the null. We observed a small increase in IBS among people with asthma, and no association between oral steroids and IBS onset among asthma patients...

..To examine relationships between weekly fluctuations in self-rated joint pain and other health outcomes among adults with osteoarthritis (OA)...

..CONCLUSION: Compared to the Caucasian contemporaries, fewer Beijing elderly suffer from hand and hip osteoarthritis. However, knee osteoarthritis is much more prevalent, affecting millions of elderly Chinese...

..To compare the prevalence of osteoarthritis (OA) of the hip among elderly persons in China and the US...

..CONCLUSION: The diameter of distant veins in limbs can be adopted as objective and quantitative indicators for parkinsonian rigidity and contribute to the evaluation of therapeutical effects...

..In the current study, we examined the expression of T beta 4 in pancreatic cancer cells, and determined the effect of exogenous T beta 4 on cytokine secretion, and signal transduction in human pancreatic cancer cells...

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..These results suggest that ACE genotype does not predict the blood pressure-lowering response to antihypertensive treatment with ACE inhibition...

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..The amelioration effect of HGF on postinfarction heart failure could not be limited to stimulating angiogenesis, anti-apoptosis, anti-fibrosis, but was also involved in the recruitment of stem cells into myocardium...

..This valuable information is particularly timely and helpful for clinicians and researchers who want to recognize the newest endeavors within the field and identify possible lines of investigation in tumor hypoxia...

..Vitamin D may improve muscle strength through a highly specific nuclear receptor in muscle tissue...

..In conclusion, the results suggested that the hybrid protein has therapeutic potential for lung carcinoma and other tumors to inhibit tumor invasion and metastasis...

..In conclusion, these results suggest that the AGT genotype does not predict the blood pressure-lowering response to antihypertensive treatment with ACE inhibitors in Chinese hypertensive patients...

..These data reveal an important outcome of aberrant ZIP4 expression in contributing to pancreatic cancer pathogenesis and progression. It may suggest a therapeutic strategy whereby ZIP4 is targeted to control pancreatic cancer growth...