Affiliation: Boston University
- Comparison of smoking-induced gene expression on Affymetrix Exon and 3'-based expression arraysXiaoling Zhang
Boston University, Boston, Massachusetts 02215, USA
Genome Inform 18:247-57. 2007..These findings suggest that the all-Exon array is a more robust platform for measuring airway epithelial gene expression and can serve as an effective tool for exploring host response to and damage from cigarette smoke...
- Comparison of nasal epithelial smoking-induced gene expression on Affymetrix Exon 1.0 and Gene 1.0 ST arraysXiaoling Zhang
Division of Computational Biomedicine, Boston University School of Medicine, 72 East Concord Street, E631, Boston, MA 02118, USA
ScientificWorldJournal 2013:951416. 2013....
- Similarities and differences between smoking-related gene expression in nasal and bronchial epitheliumXiaoling Zhang
Bioinformatics Program, Boston University, Boston, Massachusetts 02118, USA
Physiol Genomics 41:1-8. 2010..Our findings suggest that nasal epithelial gene expression may serve as a relatively noninvasive surrogate to measure physiological responses to cigarette smoke and/or other inhaled exposures in large-scale epidemiological studies...
- Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profilingLiqun Yu
Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA
Physiol Genomics 37:199-210. 2009....
- MicroRNAs as modulators of smoking-induced gene expression changes in human airway epitheliumFrank Schembri
Pulmonary Center, Boston University School of Medicine, Boston, MA 02118, USA
Proc Natl Acad Sci U S A 106:2319-24. 2009..These data indicate that mir-218 levels modulate the airway epithelial gene expression response to cigarette smoke and support a role for miRNAs in regulating host response to environmental toxins...
- Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in miceLee J Quinton
The Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, USA
J Clin Invest 122:1758-63. 2012....
- Albumin adducts of benzene oxide and 1,4-benzoquinone as measures of human benzene metabolismStephen M Rappaport
School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7400, USA
Cancer Res 62:1330-7. 2002..This study illustrates that Alb adducts can be used to investigate the dispositions of reactive metabolites of procarcinogens in humans, provided that exposures are adequately characterized in the month preceding blood collection...
- Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectEwan Birney
Nature 447:799-816. 2007..Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function...