Zhigang Xie

Summary

Affiliation: Boston University School of Medicine
Country: USA

Publications

  1. doi request reprint Molecular and cell biology of brain tumor stem cells: lessons from neural progenitor/stem cells
    Zhigang Xie
    Department of Neurosurgery, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Neurosurg Focus 24:E25. 2008
  2. doi request reprint Brain tumor stem cells
    Zhigang Xie
    Department of Neurosurgery, Boston University School of Medicine, 720 Harrison Avenue, Suite 7600, Boston, MA 02118, USA
    Neurochem Res 34:2055-66. 2009
  3. ncbi request reprint Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration
    Zhigang Xie
    Department of Pathology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    Cell 114:469-82. 2003
  4. ncbi request reprint Cdk5 phosphorylation of FAK regulates centrosome-associated miocrotubules and neuronal migration
    Zhigang Xie
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cell Cycle 3:108-10. 2004
  5. ncbi request reprint Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning
    Tianzhi Shu
    Department of Pathology, Harvard Medical School and Howard Hughes Medical Institute, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Neuron 44:263-77. 2004
  6. ncbi request reprint Cyclin-dependent kinase 5 permits efficient cytoskeletal remodeling--a hypothesis on neuronal migration
    Zhigang Xie
    Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
    Cereb Cortex 16:i64-8. 2006
  7. pmc Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool
    Zhigang Xie
    Department of Brain and Cognitive Sciences, Picower Institute for Learning and Memory, RIKEN MIT Neuroscience Research Center, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neuron 56:79-93. 2007

Collaborators

Detail Information

Publications7

  1. doi request reprint Molecular and cell biology of brain tumor stem cells: lessons from neural progenitor/stem cells
    Zhigang Xie
    Department of Neurosurgery, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Neurosurg Focus 24:E25. 2008
    ..Finally, they discuss preliminary evidence that mechanisms of BTSC-associated infiltrativeness may be similar to those underlying the migration of NPSCs and neurons...
  2. doi request reprint Brain tumor stem cells
    Zhigang Xie
    Department of Neurosurgery, Boston University School of Medicine, 720 Harrison Avenue, Suite 7600, Boston, MA 02118, USA
    Neurochem Res 34:2055-66. 2009
    ..Targeting these pathways and the vascular niche could be a principle in novel brain tumor therapies aimed to eliminate BTSCs...
  3. ncbi request reprint Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration
    Zhigang Xie
    Department of Pathology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    Cell 114:469-82. 2003
    ..Taken together, these results suggest that Cdk5 phosphorylation of FAK is critical for neuronal migration through regulation of a microtubule fork important for nuclear translocation...
  4. ncbi request reprint Cdk5 phosphorylation of FAK regulates centrosome-associated miocrotubules and neuronal migration
    Zhigang Xie
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cell Cycle 3:108-10. 2004
    ..Our study reveals a similarity between Cdk5 and Cdk1 in the regulation of neuronal migration and cell division, respectively. In addition, our study implicates FAK in a signaling pathway that directly regulates microtubules...
  5. ncbi request reprint Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning
    Tianzhi Shu
    Department of Pathology, Harvard Medical School and Howard Hughes Medical Institute, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Neuron 44:263-77. 2004
    ..These results provide strong evidence that Ndel1 interacts with LIS1 to sustain the function of dynein, which in turn impacts microtubule organization, nuclear translocation, and neuronal positioning...
  6. ncbi request reprint Cyclin-dependent kinase 5 permits efficient cytoskeletal remodeling--a hypothesis on neuronal migration
    Zhigang Xie
    Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
    Cereb Cortex 16:i64-8. 2006
    ....
  7. pmc Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool
    Zhigang Xie
    Department of Brain and Cognitive Sciences, Picower Institute for Learning and Memory, RIKEN MIT Neuroscience Research Center, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neuron 56:79-93. 2007
    ..We propose that sustaining INM may be a mechanism by which microtubule-regulating proteins maintain the neural progenitor pool during neocortical development...