M M Werler

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi Alcohol consumption and time to recognition of pregnancy
    Erika M Edwards
    Data Coordinating Center, Boston University School of Public Health, 715 Albany St, 580, Boston, MA 02118, USA
    Matern Child Health J 10:467-72. 2006
  2. pmc Effect of high parity on occurrence of anemia in pregnancy: a cohort study
    Yahya M Al-Farsi
    Department of Family Medicine and Public Health, College of Medicine and Health Sciences, Sultan Qaboos University, Oman
    BMC Pregnancy Childbirth 11:7. 2011
  3. pmc Achieving a public health recommendation for preventing neural tube defects with folic acid
    M M Werler
    Slone Epidemiology Unit, Boston University School of Public Health, Boston, Mass, USA
    Am J Public Health 89:1637-40. 1999
  4. ncbi Teratogen update: pseudoephedrine
    Martha M Werler
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02115, USA
    Birth Defects Res A Clin Mol Teratol 76:445-52. 2006
  5. pmc Hemifacial microsomia: from gestation to childhood
    Martha M Werler
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    J Craniofac Surg 20:664-9. 2009
  6. ncbi Gulf War veterans and hemifacial microsomia
    Martha M Werler
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Birth Defects Res A Clin Mol Teratol 73:50-2. 2005
  7. ncbi Demographic and reproductive factors associated with hemifacial microsomia
    Martha M Werler
    Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Cleft Palate Craniofac J 41:494-50. 2004
  8. ncbi Vasoactive exposures, vascular events, and hemifacial microsomia
    Martha M Werler
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Birth Defects Res A Clin Mol Teratol 70:389-95. 2004
  9. ncbi Findings on potential teratogens from a case-control study in Western Australia
    Martha M Werler
    Telethon Institute for Child Health Research, Subiaco, Western Australia, Australia
    Aust N Z J Obstet Gynaecol 43:443-7. 2003
  10. ncbi Association of vasoconstrictive exposures with risks of gastroschisis and small intestinal atresia
    Martha M Werler
    Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Epidemiology 14:349-54. 2003

Detail Information

Publications52

  1. ncbi Alcohol consumption and time to recognition of pregnancy
    Erika M Edwards
    Data Coordinating Center, Boston University School of Public Health, 715 Albany St, 580, Boston, MA 02118, USA
    Matern Child Health J 10:467-72. 2006
    ..This study evaluates whether women who consume alcohol are at an increased risk of recognizing pregnancy later than women who do not, adjusting for confounding factors that have been associated with alcohol consumption during pregnancy...
  2. pmc Effect of high parity on occurrence of anemia in pregnancy: a cohort study
    Yahya M Al-Farsi
    Department of Family Medicine and Public Health, College of Medicine and Health Sciences, Sultan Qaboos University, Oman
    BMC Pregnancy Childbirth 11:7. 2011
    ..The authors' aim in conducting this study was to overcome this methodological concern...
  3. pmc Achieving a public health recommendation for preventing neural tube defects with folic acid
    M M Werler
    Slone Epidemiology Unit, Boston University School of Public Health, Boston, Mass, USA
    Am J Public Health 89:1637-40. 1999
    ..This study examined 3 approaches to achieving the public health recommendation that all women of child-bearing age ingest 0.40 mg of folic acid per day to reduce the occurrence of neural tube defects (NTDs)...
  4. ncbi Teratogen update: pseudoephedrine
    Martha M Werler
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02115, USA
    Birth Defects Res A Clin Mol Teratol 76:445-52. 2006
    ..In addition, the majority of decongestant use is in oral form and the question of whether intranasal formulations carry risk has not been adequately addressed...
  5. pmc Hemifacial microsomia: from gestation to childhood
    Martha M Werler
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    J Craniofac Surg 20:664-9. 2009
    ..When data on the full study sample are available, further analyses will determine whether the preliminary findings remain and if they vary by HFM phenotype, parenting style, or indicators of social risk...
  6. ncbi Gulf War veterans and hemifacial microsomia
    Martha M Werler
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Birth Defects Res A Clin Mol Teratol 73:50-2. 2005
    ..We used data collected from a case-control study of HFM to estimate risk in relation to parental military service and, in particular, Gulf War service...
  7. ncbi Demographic and reproductive factors associated with hemifacial microsomia
    Martha M Werler
    Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Cleft Palate Craniofac J 41:494-50. 2004
    ..To identify demographic and reproductive risk factors for hemifacial microsomia in offspring...
  8. ncbi Vasoactive exposures, vascular events, and hemifacial microsomia
    Martha M Werler
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Birth Defects Res A Clin Mol Teratol 70:389-95. 2004
    ..We collected data in a case-control study to identify whether vasoactive exposures or vascular events during early pregnancy affect the risk of HFM...
  9. ncbi Findings on potential teratogens from a case-control study in Western Australia
    Martha M Werler
    Telethon Institute for Child Health Research, Subiaco, Western Australia, Australia
    Aust N Z J Obstet Gynaecol 43:443-7. 2003
    ..To examine, in Western Australian women, pregnancy use of drugs that have been found to be associated with birth defect risks in other studies...
  10. ncbi Association of vasoconstrictive exposures with risks of gastroschisis and small intestinal atresia
    Martha M Werler
    Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Epidemiology 14:349-54. 2003
    ..The present study examined risks of gastroschisis and small intestinal atresia associated with combined exposure to vasoconstrictive drugs and cigarette smoking...
  11. ncbi Maternal medication use and risks of gastroschisis and small intestinal atresia
    Martha M Werler
    Slone Epidemiology Unit, Boston University School of Public Health, Boston, MA, USA
    Am J Epidemiol 155:26-31. 2002
    ..Although pseudoephedrine has previously been shown to increase gastroschisis risk, findings of this study raise questions about interactions between medications and possible confounding by underlying illness...
  12. ncbi Epidemiologic analysis of maternal factors and amniotic band defects
    Martha M Werler
    Slone Epidemiology Center, Boston University School of Public Health, Boston, Massachusetts 02215, USA
    Birth Defects Res A Clin Mol Teratol 67:68-72. 2003
    ..Little is known about risk factors for either ARS or BWC, except that maternal age has been shown to affect risk inversely...
  13. ncbi Folic acid antagonists during pregnancy and the risk of birth defects
    S Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Brookline, Mass 02446, USA
    N Engl J Med 343:1608-14. 2000
    ..We evaluated whether the folic acid component of multivitamins is responsible for the reduction in risk by examining the associations between maternal use of folic acid antagonists and these congenital malformations...
  14. ncbi Use of a job-exposure matrix to assess occupational exposures in relation to birth defects
    C Louik
    Slone Epidemiology Unit, School of Public Health, Boston University School of Medicine, Brookline, Mass, USA
    J Occup Environ Med 42:693-703. 2000
    ..Application of the NIOSH JEM to the birth defects study database (and probably other databases as well) does not provide a useful means of assessing occupational exposures...
  15. pmc Is there epidemiologic evidence to support vascular disruption as a pathogenesis of gastroschisis?
    Martha M Werler
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Am J Med Genet A 149:1399-406. 2009
    ..However, the observation that increased ORs for some vasoactive exposures were confined to older women raises the question of whether inherent maternal factors might influence risk...
  16. ncbi Neural tube defects in relation to use of folic acid antagonists during pregnancy
    S Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Brookline, MA 02446, USA
    Am J Epidemiol 153:961-8. 2001
    ..These findings suggest that a number of FAAs may increase NTD risk, and they provide estimates of risk for selected drugs...
  17. pmc Fruit and vegetable intake and risk of upper respiratory tract infection in pregnant women
    Lin Li
    Department of Epidemiology, School of Public Health, Boston University, Boston, MA, USA
    Public Health Nutr 13:276-82. 2010
    ..The present study evaluated the association between fruit and vegetable intake and the incidence of upper respiratory tract infection (URTI) during pregnancy...
  18. ncbi First-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects
    Carol Louik
    Slone Epidemiology Center at Boston University, Boston, MA 02215, USA
    N Engl J Med 356:2675-83. 2007
    ..The risk of birth defects after antenatal exposure to selective serotonin-reuptake inhibitors (SSRIs) remains controversial...
  19. doi Socioeconomic status as a modifier of the relationship between antibiotic use during pregnancy and birthweight
    Jessica W Nelson
    Department of Environmental Health, Boston University School of Public Health, Boston, MA 02118, USA
    Birth 35:196-203. 2008
    ....
  20. pmc Gestational hypertension in pregnancies supported by infertility treatments: role of infertility, treatments, and multiple gestations
    Sonia Hernandez-Diaz
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Fertil Steril 88:438-45. 2007
    ..To investigate the association between infertility treatments and gestational hypertension and preeclampsia...
  21. pmc Selective serotonin reuptake inhibitor use and risk of gestational hypertension
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Psychiatry 166:320-8. 2009
    ..The purpose of this study was to assess the effects of treatment with selective serotonin reuptake inhibitors (SSRIs) on the risks of gestational hypertension and preeclampsia...
  22. pmc Maternal dietary glycemic intake and the risk of neural tube defects
    Mahsa M Yazdy
    Slone Epidemiology Center, Boston University, Boston, MA02215, USA
    Am J Epidemiol 171:407-14. 2010
    ..0); for high DGL, it was 1.8 (95% confidence interval: 0.8, 4.0). Diets with proportionally high DGI or DGL may put the developing fetus at risk of an NTD, adding further evidence that hyperglycemia lies within the pathogenic pathway...
  23. pmc Maternal vasoactive exposures, amniotic bands, and terminal transverse limb defects
    Martha M Werler
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA mwerler slone bu edu
    Birth Defects Res A Clin Mol Teratol 85:52-7. 2009
    ..If amniotic bands are secondary to vascular disruption, then a shared pathogenesis for each case group might be exhibited by similar risk factors...
  24. pmc Asthma in pregnancy and its pharmacologic treatment
    Carol Louik
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Ann Allergy Asthma Immunol 105:110-7. 2010
    ..Asthma is among the most common serious medical problems in pregnancy, and its prevalence may be increasing. Management is problematic because asthma may harm the fetus, yet little is known about fetal risks of asthma medications...
  25. doi Decongestant use during pregnancy and its association with preterm delivery
    Rohini K Hernandez
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts 02118, USA
    Birth Defects Res A Clin Mol Teratol 88:715-21. 2010
    ..Despite the frequent intake of decongestants during pregnancy, only one study to date has evaluated the association of decongestants with preterm delivery, and it identified a reduced risk. We examined this association in more detail...
  26. doi Hypothesis: could Epstein-Barr virus play a role in the development of gastroschisis?
    Martha M Werler
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Birth Defects Res A Clin Mol Teratol 88:71-5. 2010
    ..There is both anecdotal and published evidence showing that gastroschisis sometimes (but not always) occurs in clusters, raising the possibility that an infectious agent might be involved in its pathogenesis...
  27. ncbi Methylenetetrahydrofolate reductase polymorphisms and the risk of gestational hypertension
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, Boston, MA, USA
    Epidemiology 16:628-34. 2005
    ..It is also unknown whether the fetal genotype is relevant, or whether folic acid supplementation modifies this association...
  28. ncbi Nausea and vomiting in pregnancy: maternal characteristics and risk factors
    Carol Louik
    Slone Epidemiology Centre, Boston University, MA 02115, USA
    Paediatr Perinat Epidemiol 20:270-8. 2006
    ..Together with selected demographic characteristics that differentiate early- vs. late-onset NVP, these findings warrant further investigation...
  29. ncbi Erythromycin use during pregnancy in relation to pyloric stenosis
    Carol Louik
    Slone Epidemiology Unit, Boston University School of Medicine, Brookline, MA 02446, USA
    Am J Obstet Gynecol 186:288-90. 2002
    ....
  30. ncbi Risk of gestational hypertension in relation to folic acid supplementation during pregnancy
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, MA 02215, USA
    Am J Epidemiol 156:806-12. 2002
    ..55 (95% confidence interval: 0.39, 0.79). This finding suggests that folic acid-containing multivitamins may reduce the risk of gestational hypertension...
  31. ncbi Case-crossover and case-time-control designs in birth defects epidemiology
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Am J Epidemiol 158:385-91. 2003
    ..9 (95% CI: 1.2, 7.2), but it requires controls. In the presence of gestational time trends of exposure, the new designs do not offer clear advantages over the case-control design...
  32. ncbi Trends and predictors of folic acid awareness and periconceptional use in pregnant women
    Lolkje T W de Jong-van den Berg
    Slone Epidemiology Center, Boston University School of Public Health, Boston, Mass, USA
    Am J Obstet Gynecol 192:121-8. 2005
    ..The purpose of this study was to describe recent trends in folic acid awareness and use in the periconceptional period among pregnant women in relation to maternal sociodemographic and other relevant factors...
  33. ncbi Use of over-the-counter medications during pregnancy
    Martha M Werler
    Slone Epidemiology Center at Boston University, Boston, MA, USA
    Am J Obstet Gynecol 193:771-7. 2005
    ..We describe the patterns of over-the-counter medication use among pregnant women...
  34. ncbi Causal knowledge as a prerequisite for confounding evaluation: an application to birth defects epidemiology
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 155:176-84. 2002
    ..65 (95% confidence interval: 0.46, 0.94) should be used because the adjusted odds ratio is invalid. Causal diagrams are used to encode qualitative a priori subject matter knowledge...
  35. pmc Antidepressant use during pregnancy and the risk of preterm delivery and fetal growth restriction
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School Harvard Pilgrim Health Care Institute, 133 Brookline Ave 6th Floor, Boston, MA 02215, USA
    J Clin Psychopharmacol 29:555-60. 2009
    ..The associations between prenatal exposure to antidepressants and preterm delivery and fetal growth restriction are controversial and poorly understood. We studied the relation between antidepressant use and these outcomes...
  36. doi Periconceptional multivitamin use and infant birth weight disparities
    Heather H Burris
    Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard University, 330 Brookline Ave, Boston, MA 02215, USA
    Ann Epidemiol 20:233-40. 2010
    ..Our objective was to determine whether maternal periconceptional multivitamin (MVI) use is associated with this disparity...
  37. ncbi Can folic acid protect against congenital heart defects in Down syndrome?
    Willemijn M Meijer
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215 1201, USA
    Birth Defects Res A Clin Mol Teratol 76:714-7. 2006
    ..Our objectives were to investigate whether first-trimester FA use protects against heart anomalies among DS children...
  38. doi Sensitivity and specificity of computerized algorithms to classify gestational periods in the absence of information on date of conception
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 167:633-40. 2008
    ..However, the sensitivity of this algorithm is lower for preterm deliveries, suggesting limited validity to assess drug safety for pregnancy outcomes associated with prematurity...
  39. pmc Pre-pregnant body mass index, weight gain and the risk of delivering large babies among non-diabetic mothers
    C Kabali
    Boston University School of Public Health, Boston, Massachusetts, USA
    Int J Gynaecol Obstet 97:100-4. 2007
    ..However, previous studies have focused on the separate effects of these two indices of weight in diabetic women...
  40. ncbi Folic acid-containing supplement consumption during pregnancy and risk for oral clefts: a meta-analysis
    Rachel L Badovinac
    Department of Developmental Biology, Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA
    Birth Defects Res A Clin Mol Teratol 79:8-15. 2007
    ..We undertook this meta-analysis to test the hypothesis that nonsyndromic oral cleft birth prevalences are different for those whose mothers took folic acid-containing supplements and for those whose mothers did not...
  41. doi Gender differences in the professional and private lives of plastic surgeons
    Terri J Halperin
    Department of Plastic Surgery, Children s Hospital, Harvard Medical School and Slone Epidemiology Center, Boston University, Boston, MA, USA
    Ann Plast Surg 64:775-9. 2010
    ..Nevertheless, female plastic surgeons appear to have similar career satisfaction and are no more likely to retire earlier or more frequently than male plastic surgeons...
  42. ncbi Risk factors for persistent pulmonary hypertension of the newborn
    Sonia Hernandez-Diaz
    Slone Epidemiology Center at Boston University, 1010 Commonwealth Ave, Boston, MA 02215, USA
    Pediatrics 120:e272-82. 2007
    ..We performed a case-control study to determine possible antenatal and perinatal predictors of persistent pulmonary hypertension of the newborn...
  43. ncbi Low maternal alcohol consumption during pregnancy and oral clefts in offspring: the Slone Birth Defects Study
    Katie A Meyer
    Department of Applied Medical Sciences, School of Applied Science, Engineering, and Technology, University of Southern Maine, Portland, Maine, USA
    Birth Defects Res A Clin Mol Teratol 67:509-14. 2003
    ..The association between maternal alcohol consumption during pregnancy and oral clefts in offspring remains unclear. We studied this relation in a case-control surveillance study of birth defects...
  44. ncbi Maternal use of acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs), and muscular ventricular septal defects
    Mario A Cleves
    Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Arkansas Center for Birth Defects Research and Prevention, 11219 Financial Centre Parkway, Little Rock, AR 72211, USA
    Birth Defects Res A Clin Mol Teratol 70:107-13. 2004
    ..We evaluated the association between mVSDs and maternal use of acetaminophen or NSAIDs adjusting for fever...
  45. ncbi Maternal obesity, gestational diabetes, and central nervous system birth defects
    James L Anderson
    The University of Texas, Houston Health Science Center, School of Public Health, Houston, Texas, USA
    Epidemiology 16:87-92. 2005
    ..Our objective was to evaluate whether gestational diabetes influenced the association of prepregnancy maternal obesity and risks for CNS birth defects...
  46. ncbi Fat intake and the risk of gastroschisis
    Anna Maria Siega-Riz
    Department of Nutrition, School of Public Health, University of North Carolina, Chapel Hill, 27516, USA
    Birth Defects Res A Clin Mol Teratol 76:241-5. 2006
    ..The objective of this study was to examine the association between dietary fats and gastroschisis and whether maternal age modified this association...
  47. ncbi Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn
    Christina D Chambers
    Department of Pediatrics, University of California, San Diego, La Jolla, CA 92103, USA
    N Engl J Med 354:579-87. 2006
    ..We performed a case-control study to assess whether PPHN is associated with exposure to SSRIs during late pregnancy...
  48. doi Maternal exposure to statins and risk for birth defects: a case-series approach
    Emily E Petersen
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Am J Med Genet A 146:2701-5. 2008
  49. doi Antifungal drugs and the risk of selected birth defects
    Tonia C Carter
    Department of Epidemiology, School of Public Health, State University of New York at Albany, Albany, USA
    Am J Obstet Gynecol 198:191.e1-7. 2008
    ..This study examined whether first-trimester antifungal drug use was associated with the risk of selected birth defects...
  50. ncbi Association between prepregnancy maternal body mass index and the risk of having an infant with a congenital diaphragmatic hernia
    D Kim Waller
    School of Public Health, University of Texas Houston Health Science Center, Houston, Texas 77225, USA
    Birth Defects Res A Clin Mol Teratol 67:73-6. 2003
    ..The objective of the current study was to examine the association between maternal body mass index and the risk of a CDH-affected offspring based on a larger number of cases of CDH...
  51. ncbi Maternal corticosteroid use and orofacial clefts
    Suzan L Carmichael
    March of Dimes Foundation California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, CA, USA
    Am J Obstet Gynecol 197:585.e1-7; discussion 683-4, e1-7. 2007
    ..The purpose of this study was to examine whether maternal corticosteroid use during pregnancy is associated with delivering an infant with an orofacial cleft...
  52. ncbi Maternal hypertension, antihypertensive medication use, and the risk of severe hypospadias
    Alissa R Caton
    Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, Rensselaer, New York, USA
    Birth Defects Res A Clin Mol Teratol 82:34-40. 2008
    ..The objective of this study was to investigate the relationship between high blood pressure, antihypertensive medication use, and severe hypospadias...

Research Grants2