Research Topics
| Zhiping WengSummaryAffiliation: Boston University Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
FAST: a novel protein structure alignment algorithmJianhua Zhu
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 58:618-27. 2005..Typical pairwise alignments take FAST less than a second with a Pentium III 1.2GHz CPU. FAST software and a web server are available at http://biowulf.bu.edu/FAST/...- Computational determination of the structure of rat Fc bound to the neonatal Fc receptorZ Weng
Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
J Mol Biol 282:217-25. 1998.... - M-ZDOCK: a grid-based approach for Cn symmetric multimer dockingBrian Pierce
Bioinformatics Program, Boston University, Boston, MA, USA
Bioinformatics 21:1472-8. 2005..In addition, the running times are 30-40% faster for M-ZDOCK. AVAILABILITY: M-ZDOCK is freely available to academic users at http://zlab.bu.edu/m-zdock/ CONTACT: SUPPLEMENTARY INFORMATION: http://zlab.bu.edu/m-zdock... - Managing biological sequence and protein structure dataZhiping Weng
Department of Biomedical Engineering, Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
OMICS 7:25-6. 2003 - A novel shape complementarity scoring function for protein-protein dockingRong Chen
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 51:397-408. 2003..Our docking program ZDOCK has been parallelized and the average computing time is 4 minutes using sixteen IBM SP3 processors. Both ZDOCK and the benchmark are freely available to academic users (http://zlab.bu.edu/~ rong/dock)... - Protein-Protein Docking Benchmark 2.0: an updateJulian Mintseris
Boston University Bioinformatics Program, Boston, Massachusetts 02215, USA
Proteins 60:214-6. 2005..The new benchmark provides a platform for evaluating the progress of docking methods on a wide variety of targets. The new version of the benchmark is available to the public at http://zlab.bu.edu/benchmark2... - ZDOCK and RDOCK performance in CAPRI rounds 3, 4, and 5Kevin Wiehe
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 60:207-13. 2005..These results are evidence that ZDOCK in combination with RDOCK is capable of making accurate predictions on a diverse set of protein complexes... - The performance of ZDOCK and ZRANK in rounds 6-11 of CAPRIKevin Wiehe
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 69:719-25. 2007..Here we outline a practical and successful docking strategy, given limited prior biological knowledge of the complex to be predicted... 
CARRIE web service: automated transcriptional regulatory network inference and interactive analysisPeter M Haverty
Bioinformatics Program and Biomedical Engineering Department, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 32:W213-6. 2004..Our service also provides Gene Ontology annotation to aid the user in forming hypotheses about the role of each gene in the cellular response. The CARRIE web service is freely available at http://zlab.bu.edu/CARRIE-web...- SeqVISTA: a new module of integrated computational tools for studying transcriptional regulationZhenjun Hu
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 32:W235-41. 2004..bu.edu/SeqVISTA/web.jnlp, provided that Java Web Start has been installed. In addition, a stand-alone version of the program can be downloaded and run locally. It can be obtained at http://zlab.bu.edu/SeqVISTA... - Genetic and pharmacological inactivation of adenosine A2A receptor reveals an Egr-2-mediated transcriptional regulatory network in the mouse striatumLiqun Yu
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Physiol Genomics 23:89-102. 2005..Taken together, these results strongly support the existence of an Egr-2-directed transcriptional regulatory network controlled by striatal A2ARs... - Genome-wide decoding of hierarchical modular structure of transcriptional regulation by cis-element and expression clusteringDmitriy Leyfer
Bioinformatics Program, Boston University, Boston, MA 02215, USA
Bioinformatics 21:ii197-203. 2005..We set out to devise a method that would identify TMs while avoiding arbitrary thresholds on TM sizes and number... - MotifViz: an analysis and visualization tool for motif discoveryYutao Fu
Bioinformatics Program, Boston University, Boston, MA 02215, USA
Nucleic Acids Res 32:W420-3. 2004..For comparison, we have also implemented the simple motif-matching program Possum. MotifViz provides uniform and intuitive input and output formats for all four programs. It can be accessed at http://biowulf.bu.edu/MotifViz... - Protein-protein docking: overview and performance analysisKevin Wiehe
Bioinformatics Program, Boston University, Boston, MA, USA
Methods Mol Biol 413:283-314. 2008..Finally, we perform regression analysis to better understand the strengths and weaknesses of ZDOCK and to suggest areas of future development for protein-docking algorithms in general... - Integrating statistical pair potentials into protein complex predictionJulian Mintseris
Bioinformatics Program, Boston University, Massachusetts 02215, USA
Proteins 69:511-20. 2007..Furthermore, we show that the new potential performs well on antibody-antigen complexes, with most predictions clustering around the Complementarity Determining Regions of antibodies without any manual intervention... - A protein-protein docking benchmarkRong Chen
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 52:88-91. 2003..The benchmark is available at (http://zlab.bu.edu/~rong/dock/benchmark.shtml)... - Improvement of TRANSFAC matrices using multiple local alignment of transcription factor binding site sequencesYutao Fu
Bioinformatics Program, Boston University, Boston, MA 02215, USA
Genome Inform 16:68-72. 2005..One of the alignment programs, GLAM, produced comparable matrices in terms of the average ranking of true positive sites across the whole test set of sequences... - Identification of conserved structural features at sequentially degenerate locations in transcription factor binding sitesHeather E Burden
Bioinformatics Program, Boston University, Boston, MA 02215, USA
Genome Inform 16:49-58. 2005..Availability: ICSF is freely available to academic users at http://zlab.bu.edu/ICSF . Supplementary information: http://zlab.bu.edu/ICSF ... - Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profilingLiqun Yu
Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA
Physiol Genomics 37:199-210. 2009.... - Limited agreement among three global gene expression methods highlights the requirement for non-global validationPeter M Haverty
Bioinformatics Program, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Bioinformatics 20:3431-41. 2004..Furthermore, analyses of mRNA abundance distributions indicate limitations in the EBE and SAGE methods at both high- and low-expression levels... - Site2genome: locating short DNA sequences in whole genomesMartin C Frith
Bioinformatics Program, Boston University, MA 02215, USA
Bioinformatics 20:1468-9. 2004..AVAILABILITY: http://zlab.bu.edu/site2genome/.. - Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genomeHualin Xi
Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America
PLoS Genet 3:e136. 2007..Finally, we found that approximately 8% of the genome overlaps a DNaseI HS site in at least one the six cell lines studied, indicating that a significant percentage of the genome is potentially functional... 
Performance of ZDOCK and ZRANK in CAPRI rounds 13-19Howook Hwang
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 78:3104-10. 2010....- RDOCK: refinement of rigid-body protein docking predictionsLi Li
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 53:693-707. 2003..RDOCK is freely available to academic users at http://zlab.bu.edu/ approximately rong/dock... - ZDOCK: an initial-stage protein-docking algorithmRong Chen
Bioinformatics Program, Boston University, Boston, Massachusetts, USA
Proteins 52:80-7. 2003..All four scoring functions have been integrated into our Fast Fourier Transform based docking algorithm ZDOCK, which is freely available to academic users at http://zlab.bu.edu/~ rong/dock... - Cluster-Buster: Finding dense clusters of motifs in DNA sequencesMartin C Frith
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 31:3666-8. 2003..Cluster-Buster is the third incarnation of our software for finding clusters of pre-specified motifs in DNA sequences. We offer a Cluster-Buster web server at http://zlab.bu.edu/cluster-buster/... - An avidin-like domain that does not bind biotin is adopted for oligomerization by the extracellular mosaic protein fibropellinItai Yanai
Biomedical Engineering Department, 44 Cummington Street, Boston University, Boston, MA 02215, USA
Protein Sci 14:417-23. 2005..Finally, based upon the oligomerization of the avidin-like domain, we propose a model for the overall structure of the apical lamina... - Less is more: towards an optimal universal description of protein foldsJoseph D Szustakowski
Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
Bioinformatics 21:ii66-71. 2005..Dictionaries generated using the training set had high coverage over the folds in the testing set, suggesting that dictionary entries reflect general features of protein structures and should be capable of describing novel protein folds... - Combinations of affinity-enhancing mutations in a T cell receptor reveal highly nonadditive effects within and between complementarity determining regions and chainsBrian G Pierce
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Biochemistry 49:7050-9. 2010..These results highlight the complex nature of TCR association and binding and will be informative in future design efforts that combine multiple mutant residues... - Transcription factor binding and modified histones in human bidirectional promotersJane M Lin
Department of Biomedical Engineering, Boston University, Boston, Massachusetts, 02215, USA
Genome Res 17:818-27. 2007.... - CisML: an XML-based format for sequence motif detection softwarePeter M Haverty
Bioinformatics Program, Boston University, Boston, MA 02215, USA
Bioinformatics 20:1815-7. 2004..AVAILABILITY: http://zlab.bu.edu/CisML/ SUPPLEMENTARY INFORMATION: Example CisML-formatted data and XSL stylesheets for report generation are available along with the sample output... - Computational inference of transcriptional regulatory networks from expression profiling and transcription factor binding site identificationPeter M Haverty
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 32:179-88. 2004..The predicted networks were validated with comparisons to literature sources, experimental TF binding data, and gene ontology biological process information... - Finding functional sequence elements by multiple local alignmentMartin C Frith
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 32:189-200. 2004..Detection of transcription factor-binding motifs is limited by the motifs' intrinsic subtlety rather than by inadequacy of the alignment optimization procedure... - The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genomeYutao Fu
Bioinformatics Program, Boston University, Boston, Massachusetts, USA
PLoS Genet 4:e1000138. 2008..We suggest that binding of CTCF provides an anchor point for positioning nucleosomes, and chromatin remodeling is an important component of CTCF function... - PromoSer: improvements to the algorithm, visualization and accessibilityAnason S Halees
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 32:W191-4. 2004..PromoSer now also supports queries using a SOAP-based interface and XML-based responses. The service is publicly available at http://biowulf.bu.edu/zlab/PromoSer... - ZDOCK predictions for the CAPRI challengeRong Chen
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 52:68-73. 2003..Implications of the treatment of prior biological information as well as contributions of manual inspection to docking predictions are also discussed... - Analysis of overrepresented motifs in human core promoters reveals dual regulatory roles of YY1Hualin Xi
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Genome Res 17:798-806. 2007..We also discuss the evolutionary advantages of housing a transcriptional element inside the transcript in terms of the migration of these genes in the human genome... - Protein-protein docking benchmark version 3.0Howook Hwang
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 73:705-9. 2008..0 will facilitate the development of new algorithms that require a large number of training examples. Benchmark 3.0 is available to the public at http://zlab.bu.edu/benchmark... - Detection of functional DNA motifs via statistical over-representationMartin C Frith
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 32:1372-81. 2004..It also demonstrates superior performance over two contingency table based over-representation methods. In conclusion, Clover has the potential to greatly accelerate characterization of signals that regulate transcription... - Identification of functional modules that correlate with phenotypic difference: the influence of network topologyJui Hung Hung
Bioinformatics Program, Boston University, 24 Cummington Street, Boston, MA 02215, USA
Genome Biol 11:R23. 2010..We present a method that takes account of such information - expressed in terms of the topology of a correlation network - and we apply the method in the context of current procedures for gene set enrichment analysis... - Systematic detection of statistically overrepresented DNA motif association rulesJane Marie Lin
Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
Genome Inform 17:124-33. 2006..Applying CAYCE to human promoters in 1% of the human genome, we discover that motif clusters containing five repetitions of SP1 are the most statistically significant... - Structure-based design of a T-cell receptor leads to nearly 100-fold improvement in binding affinity for pepMHCJaafar N Haidar
Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
Proteins 74:948-60. 2009..Four of the point mutations that improved binding were then combined to give a mutant TCR that binds the pepMHC 99 times more strongly than the wild-type TCR... - Docking unbound proteins using shape complementarity, desolvation, and electrostaticsRong Chen
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 47:281-94. 2002..If combined with a post-processing method, our algorithm may provide a general solution to the unbound docking problem. Our program, called ZDOCK, is freely available to academic users (http://zlab.bu.edu/~rong/dock/)... - Structure, function, and evolution of transient and obligate protein-protein interactionsJulian Mintseris
Bioinformatics Program and Biomedical Engineering Department, Boston University, Boston, MA 02215, USA
Proc Natl Acad Sci U S A 102:10930-5. 2005..In contrast, the plasticity inherent in transient interactions leads to an increased rate of substitution for the interface residues and leaves little or no evidence of correlated mutations across the interface... - PromoSer: A large-scale mammalian promoter and transcription start site identification serviceAnason S Halees
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 31:3554-9. 2003..The service is publicly available at http://biowulf.bu.edu/zlab/PromoSer/... - Atomic contact vectors in protein-protein recognitionJulian Mintseris
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 53:629-39. 2003..With this method, we arrive at a nonredundant set of 209 recognition complexes--the largest set reported so far... - A computational framework for optimal masking in the synthesis of oligonucleotide microarraysSimon Kasif
Center for Advanced Genomic Technology, Bioinformatics Program and Biomedical Engineering Department, Boston University, Boston, MA 02215, USA
Nucleic Acids Res 30:e106. 2002..The problem was introduced by Hubbell et al. Here, we formalize the problem, obtain precise bounds on its complexity and devise several computational solutions... - A combination of rescoring and refinement significantly improves protein docking performanceBrian Pierce
Bioinformatics Program, Boston University, Boston, Massachusetts 02215, USA
Proteins 72:270-9. 2008..This shows the effective combination of independently developed docking protocols (ZDOCK/ZRANK, and RosettaDock), indicating that using diverse search and scoring functions can improve protein docking results... - Characterization of genomic organization of the adenosine A2A receptor gene by molecular and bioinformatics analysesLiqun Yu
Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
Brain Res 1000:156-73. 2004..This raises the possibility of generating multiple tissue-specific A(2A)R mRNA species by alternative promoters with varying regulatory susceptibility... - A simple method for improving the specificity of anti-methyl histone antibodiesCaroline Connor
Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, USA
Epigenetics 5:392-5. 2010.... - Optimizing protein representations with information theoryJulian Mintseris
Bioinformatics Program, Boston University, Boston MA 02215, USA
Genome Inform 15:160-9. 2004..Implications for further structural studies are discussed... - ZRANK: reranking protein docking predictions with an optimized energy functionBrian Pierce
Bioinformatics Program, Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
Proteins 67:1078-86. 2007..ZRANK can be applied either as a refinement protocol in itself or as a preprocessing stage to enrich the well-ranked hits prior to further refinement... - SeqVISTA: a graphical tool for sequence feature visualization and comparisonZhenjun Hu
Bioinformatics Program, Boston University, Boston, MA, 02215, USA
BMC Bioinformatics 4:1. 2003..But now you want to see what other features have been annotated close by, and this information is buried several screenfuls higher up the web page... - Quantitative analysis of single nucleotide polymorphisms within copy number variationSooHyun Lee
Bioinformatics Program, Boston University, Boston, MA, USA
PLoS ONE 3:e3906. 2008..This suggests that a significant number of SNPs must be within these regions, which may cause deviation from HWE... - HugeIndex: a database with visualization tools for high-density oligonucleotide array data from normal human tissuesPeter M Haverty
Bioinformatics Program, Boston University, 44 Cummington Street, Boston, MA 02115, USA
Nucleic Acids Res 30:214-7. 2002..We provide interactive tools for researchers to query and visualize our data over the Internet. To facilitate data analysis, we cross-reference each gene on the array with its annotation in the LocusLink database at NCBI... - In silico meets in vivoZhiping Weng
Bioinformatics Program, Boston University, Cummington Street, Boston, MA 02215, USA
Genome Biol 9:302. 2008..A report of the 6th Georgia Tech-Oak Ridge National Lab International Conference on Bioinformatics 'In silico Biology: Gene Discovery and Systems Genomics', Atlanta, USA, 15-17 November, 2007... - Genomic binding profiles of functionally distinct RNA polymerase III transcription complexes in human cellsZarmik Moqtaderi
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA
Nat Struct Mol Biol 17:635-40. 2010..Our results suggest that human Pol III complexes associate preferentially with regions near functional Pol II promoters and that TFIIIC-mediated recruitment of TFIIIB is regulated in a locus-specific manner... - Identification and validation of a novel cell-recognition site (KNEED) on the 8th type III domain of fibronectinJoyce Y Wong
Department of Biomedical Engineering, Boston University, MA 02215, USA
Biomaterials 23:3865-70. 2002..As more sequence and crystallographic data become available, computational approaches may aid in the identification of new targets for applications where biorecognition plays a key role... - Protein therapeutics: promises and challenges for the 21st centuryZhiping Weng
Biomedical Engineering Department and Bioinformatics Program, Boston University, Boston MA 02215, USA
Trends Biotechnol 20:29-35. 2002..Taken collectively, these advances will usher in an era of predictive medicine, which will move medical practice from reactive therapy after disease onset, to proactive prevention... - Nucleosome positioning signals in genomic DNAHeather E Peckham
Bioinformatics Program, Boston University, Boston, MA 02215, USA
Genome Res 17:1170-7. 2007..Finally, we show that intrinsic nucleosome positioning signals are both more inhibitory and more variable in promoter regions than in open reading frames in S. cerevisiae... - Statistical significance of clusters of motifs represented by position specific scoring matrices in nucleotide sequencesMartin C Frith
Bioinformatics Program, Boston University, 44 Cummington Street, Boston MA 02215, USA
Nucleic Acids Res 30:3214-24. 2002..Thus, discovery of additional signals that belong to these regulatory regions will be the key to future progress... - Optical recognition of converted DNA nucleotides for single-molecule DNA sequencing using nanopore arraysBen McNally
Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
Nano Lett 10:2237-44. 2010..We show that signals from multiple nanopores can be detected simultaneously, allowing straightforward parallelization to large nanopore arrays... - Gene discovery in the auditory system: characterization of additional cochlear-expressed sequencesBarbara L Resendes
Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA 02115, USA
J Assoc Res Otolaryngol 3:45-53. 2002..Identification of additional known genes, ESTs, and cochlear-specific ESTs provides new candidate genes for both syndromic and nonsyndromic deafness disorders... - A global map of p53 transcription-factor binding sites in the human genomeChia-Lin Wei
Genome Institute of Singapore, Singapore 138672
Cell 124:207-19. 2006.... - Assessing computational tools for the discovery of transcription factor binding sitesMartin Tompa
Department of Computer Science and Engineering, Box 352350, University of Washington, Seattle, Washington 98195 2350, USA
Nat Biotechnol 23:137-44. 2005..The purpose of the current assessment is twofold: to provide some guidance to users regarding the accuracy of currently available tools in various settings, and to provide a benchmark of data sets for assessing future tools... - Examining the independent binding assumption for binding of peptide epitopes to MHC-I moleculesBjorn Peters
Institut fur Biochemie, Charite, Humboldt Universitat Berlin, Monbijoustr 2, 10117 Berlin, Germany
Bioinformatics 19:1765-72. 2003..g. artificial neural networks). We aim to compare the prediction accuracies of these methods, and quantify the impact of interactions between peptide positions... - Global mapping of c-Myc binding sites and target gene networks in human B cellsKaren I Zeller
Department of Medicine and The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Proc Natl Acad Sci U S A 103:17834-9. 2006.... - Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targetsDavid S Johnson
Department of Genetics, Stanford University Medical Center, Stanford, California 94305, USA
Genome Res 18:393-403. 2008..The spike-in DNA samples and the data presented here provide a stable benchmark against which future ChIP platforms, protocol improvements, and analysis methods can be evaluated... - Main-chain conformational tendencies of amino acidsRobert J Anderson
Serono Reproductive Biology Institute, One Technology Place, Rockland, Massachusetts, USA
Proteins 60:679-89. 2005..In addition to these conclusions, we here present an amino acid substitution table derived from experimental data... - Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectEwan Birney
Nature 447:799-816. 2007..Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function... - High-resolution mapping and characterization of open chromatin across the genomeAlan P Boyle
Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA
Cell 132:311-22. 2008..In addition, and unexpectedly, our analyses have uncovered detailed features of nucleosome structure... - Ancestral and consensus envelope immunogens for HIV-1 subtype CDenise L Kothe
Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Virology 352:438-49. 2006..These results establish the utility of centralized HIV-1 subtype C Env immunogens and warrant their continued evaluation as potential components of future AIDS vaccines... - Statistical analysis of the genomic distribution and correlation of regulatory elements in the ENCODE regionsZhengdong D Zhang
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520, USA
Genome Res 17:787-97. 2007..Data sets associated with histone modifications have particularly strong correlations. Finally, we show how the correlations between factors change when only regulatory elements far from the transcription start sites are considered... - Epitope tagging of endogenous proteins for genome-wide ChIP-chip studiesXiaodong Zhang
Department of Genetics and Case Comprehensive Cancer Center, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA
Nat Methods 5:163-5. 2008..The knock-in approach provides a general solution for the study of proteins to which antibodies are substandard or not available... - Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteinsDenise L Kothe
Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Virology 360:218-34. 2007....
Research Grants
- Identification of Transcriptional Factor Binding Sites in Human PromotersZhiping Weng; Fiscal Year: 2007..The data generated in this project will be the first systematic functional analysis of TF binding sites at base-pair resolution. ..