X Wang

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study
    Xiaobin Wang
    Department of Pediatrics, Boston University School of Medicine and Boston Medical Center, Massachusetts, USA
    Fertil Steril 79:577-84. 2003
  2. ncbi request reprint Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight
    Xiaobin Wang
    Department of Pediatrics, Boston University School of Medicine and Boston Medical Center, 91 E Concord St, Maternity 4, Boston, MA 02118, USA
    JAMA 287:195-202. 2002
  3. ncbi request reprint Molecular epidemiology of preterm delivery: methodology and challenges
    X Wang
    Department of Pediatrics, Boston University School of Medicine, 91 E Concord Street, Boston, MA 02118, USA
    Paediatr Perinat Epidemiol 15:63-77. 2001
  4. ncbi request reprint Genetic susceptibility to benzene and shortened gestation: evidence of gene-environment interaction
    X Wang
    Department of Pediatrics, Boston University School of Medicine and Boston Medical Center, MA 02118, USA
    Am J Epidemiol 152:693-700. 2000
  5. doi request reprint Association of adipokines with blood pressure in rural Chinese adolescents
    H Wang
    The Mary Ann and J Milburn Smith Child Health Research Program, Department of Pediatrics, Northwestern University Feinberg School of Medicine and Children s Memorial Hospital and Children s Memorial Research Center, Chicago, IL, USA
    J Hum Hypertens 26:493-501. 2012
  6. pmc Association between short sleep duration and the risk of sensitization to food and aero allergens in rural Chinese adolescents
    S Zhang
    Mary Ann and J Milburn Smith Child Health Research Program, Department of Pediatrics, Children s Memorial Research Center, Children s Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Clin Exp Allergy 41:547-55. 2011
  7. ncbi request reprint Exposure-response relationship between paternal smoking and children's pulmonary function
    S A Venners
    Program for Population Genetics, Harvard School of Public Health, Boston, Massachusetts 02115-6096, USA
    Am J Respir Crit Care Med 164:973-6. 2001
  8. ncbi request reprint Tofu consumption and blood lead levels in young Chinese adults
    C Chen
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 153:1206-12. 2001
  9. pmc Serum DDT, age at menarche, and abnormal menstrual cycle length
    F Ouyang
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Occup Environ Med 62:878-84. 2005
  10. pmc Gene-vitamin D interactions on food sensitization: a prospective birth cohort study
    X Liu
    Mary Ann and J Milburn Smith Child Health Research Program, Children s Memorial Hospital, Children s Memorial Research Center, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Allergy 66:1442-8. 2011

Collaborators

Detail Information

Publications74

  1. ncbi request reprint Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study
    Xiaobin Wang
    Department of Pediatrics, Boston University School of Medicine and Boston Medical Center, Massachusetts, USA
    Fertil Steril 79:577-84. 2003
    ..To examine rates of conception and pregnancy loss and their relations with time to clinical pregnancy and reproductive outcomes...
  2. ncbi request reprint Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight
    Xiaobin Wang
    Department of Pediatrics, Boston University School of Medicine and Boston Medical Center, 91 E Concord St, Maternity 4, Boston, MA 02118, USA
    JAMA 287:195-202. 2002
    ..Little is known about genetic susceptibility to cigarette smoke in relation to adverse pregnancy outcomes...
  3. ncbi request reprint Molecular epidemiology of preterm delivery: methodology and challenges
    X Wang
    Department of Pediatrics, Boston University School of Medicine, 91 E Concord Street, Boston, MA 02118, USA
    Paediatr Perinat Epidemiol 15:63-77. 2001
    ..The findings from this study should improve our understanding of genetic influences on PTD and gene-environment interactions...
  4. ncbi request reprint Genetic susceptibility to benzene and shortened gestation: evidence of gene-environment interaction
    X Wang
    Department of Pediatrics, Boston University School of Medicine and Boston Medical Center, MA 02118, USA
    Am J Epidemiol 152:693-700. 2000
    ..This study provides evidence of gene-environment interaction and supports further assessment of the role of genetic susceptibility in the evaluation of reproductive toxins...
  5. doi request reprint Association of adipokines with blood pressure in rural Chinese adolescents
    H Wang
    The Mary Ann and J Milburn Smith Child Health Research Program, Department of Pediatrics, Northwestern University Feinberg School of Medicine and Children s Memorial Hospital and Children s Memorial Research Center, Chicago, IL, USA
    J Hum Hypertens 26:493-501. 2012
    ..In these relatively lean Chinese adolescents, leptin was positively associated with BP in both genders, but was adiposity/IR dependent. Adiponectin was negatively associated with SBP in males, independent of adiposity/IR...
  6. pmc Association between short sleep duration and the risk of sensitization to food and aero allergens in rural Chinese adolescents
    S Zhang
    Mary Ann and J Milburn Smith Child Health Research Program, Department of Pediatrics, Children s Memorial Research Center, Children s Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Clin Exp Allergy 41:547-55. 2011
    ..However, there have been no previous studies investigating the potential relationship between altered sleep duration and allergen sensitization...
  7. ncbi request reprint Exposure-response relationship between paternal smoking and children's pulmonary function
    S A Venners
    Program for Population Genetics, Harvard School of Public Health, Boston, Massachusetts 02115-6096, USA
    Am J Respir Crit Care Med 164:973-6. 2001
    ..We conclude that there is a monotonic exposure-response relationship between paternal smoking and decline of pulmonary function in children in this rural Chinese population...
  8. ncbi request reprint Tofu consumption and blood lead levels in young Chinese adults
    C Chen
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 153:1206-12. 2001
    ..In conclusion, the authors found a significant inverse dose-response relation between tofu consumption and blood lead levels in this Chinese population...
  9. pmc Serum DDT, age at menarche, and abnormal menstrual cycle length
    F Ouyang
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Occup Environ Med 62:878-84. 2005
    ..Although dichlorodiphenyl trichloroethane (DDT) exposure is known to affect human endocrine function, few previous studies have investigated the effects of DDT exposure on age at menarche or menstrual cycle length...
  10. pmc Gene-vitamin D interactions on food sensitization: a prospective birth cohort study
    X Liu
    Mary Ann and J Milburn Smith Child Health Research Program, Children s Memorial Hospital, Children s Memorial Research Center, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Allergy 66:1442-8. 2011
    ..However, the epidemiological evidence is conflicting. We aim to examine whether cord blood VDD is associated with FS and whether such association can be modified by genetic variants in a prospective birth cohort...
  11. pmc Genetic and environmental contributions to allergen sensitization in a Chinese twin study
    X Liu
    Mary Ann and J Milburn Smith Child Health Research Program, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, Chicago, IL, USA
    Clin Exp Allergy 39:991-8. 2009
    ..Allergic disease is on the rise worldwide. Effective prevention of allergic disease requires comprehensive understanding of the factors that contribute to its intermediate phenotypes, such as sensitization to common allergens...
  12. ncbi request reprint Pharmaco-proteomics opportunities for individualizing neurovascular treatment
    M M Ning
    Clinical Proteomics Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Neurol Res 35:448-56. 2013
    ..In the future, this clinical proteomics approach may help to improve patient selection, ensure more precise clinical phenotyping for clinical trials, and individualize patient treatment...
  13. pmc Cox-2 inhibition enhances the activity of sunitinib in human renal cell carcinoma xenografts
    X Wang
    Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Br J Cancer 108:319-26. 2013
    ..As COX-2 is a known mediator of tumour growth, we explored the potential benefit of COX-2 inhibition in combination with VEGFR inhibition in attempts at delaying tumour progression on Su...
  14. pmc Stress and dysmenorrhoea: a population based prospective study
    L Wang
    Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
    Occup Environ Med 61:1021-6. 2004
    ..Dysmenorrhoea is the most common gynaecological disorder in women of reproductive age. Despite the association between stress and pregnancy outcomes, few studies have examined the possible link between stress and dysmenorrhoea...
  15. pmc Simultaneous PML-IRIS after discontinuation of natalizumab in a patient with MS
    S Gheuens
    Division of Neurovirology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Neurology 78:1390-3. 2012
    ..We describe a patient with MS who presented with simultaneous PML-IRIS 2 months after stopping natalizumab for other reasons. CASE REPORT and..
  16. pmc Activation of toll-like receptor-3 induces interferon-lambda expression in human neuronal cells
    L Zhou
    Division of Allergy and Immunology, Joseph Stokes, Jr Research Institute at The Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Neuroscience 159:629-37. 2009
    ....
  17. pmc Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia
    S R Lee
    Neuroprotection Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Neuroscience 150:50-7. 2007
    ..Taken together, these data suggest that endogenous tPA contributes to hippocampal injury after cerebral ischemia, and these pathophysiologic pathways may involve links to aberrant activation of caspases and MMPs...
  18. ncbi request reprint Adiposity measures and blood pressure in Chinese children and adolescents
    H Wang
    Mary Ann and J Milburn Smith Child Health Research Program, Department of Pediatrics, Northwestern University Feinberg School of Medicine and Children s Memorial Hospital and Children s Memorial Research Center, Chicago, IL 60614, USA
    Arch Dis Child 93:738-44. 2008
    ..To investigate the association of adiposity measures with blood pressure (BP) in Chinese children and adolescents...
  19. ncbi request reprint Association between tPA therapy and raised early matrix metalloproteinase-9 in acute stroke
    M Ning
    Stroke Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Neurology 66:1550-5. 2006
    ..The authors investigated plasma MMP9 and its endogenous inhibitor, tissue inhibitor of metalloproteinase (TIMP1), in tPA-treated and -untreated stroke patients...
  20. ncbi request reprint Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of Captopril in women
    X Fan
    Hypertension Division, Department of Cardiology, Ministry of Education and Sino German Laboratory for Molecular Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Clin Pharmacol Ther 82:187-96. 2007
    ..3 mm Hg lower in ACE2 T allele carriers than in CC genotype carriers (P=0.019) in women. We conclude that the ACE2 T allele confers a high risk for hypertension and reduced antihypertensive response to ACE inhibitors...
  21. ncbi request reprint A common polymorphism in the 3'UTR of cyclooxygenase 2/prostaglandin synthase 2 gene and risk of lung cancer in a Chinese population
    Z Hu
    Department of Epidemiology and Biostatistics, Nanjing Medical University School of Public Health, Nanjing 210029, China
    Lung Cancer 48:11-7. 2005
    ..10-9.00). These findings indicate that the COX-2 T8473C polymorphism may contribute to lung cancer susceptibility in the Chinese population. Further larger molecular epidemiological studies are warranted to confirm these findings...
  22. ncbi request reprint Interleukin 3 and schizophrenia: the impact of sex and family history
    X Chen
    Department of Psychiatry and Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
    Mol Psychiatry 12:273-82. 2007
    ..They may explain the sex-specific associations and be functional for the expression of IL3 gene...
  23. ncbi request reprint DNA repair gene XPD polymorphism and lung cancer risk: a meta-analysis
    Z Hu
    Department of Epidemiology and Biostatistics, Nanjing Medical University School of Public Health, Nanjing 210029, China
    Lung Cancer 46:1-10. 2004
    ..Large multi-center studies with precise design, and stratified/adjusted analyses of the gene-gene (haplotypes) and gene-environment interactions are needed...
  24. ncbi request reprint Variants in the catechol-o-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families
    X Chen
    Department of Psychiatry and Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University, 800 E Leigh Street, Richmond, VA 23298, USA
    Mol Psychiatry 9:962-7. 2004
    ..We concluded that COMT gene is associated with schizophrenia and carries a small but significant risk to the susceptibility in the Irish subjects...
  25. ncbi request reprint Mannose binding lectin gene polymorphisms and asthma
    X Wang
    Department of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima City, Japan
    Clin Exp Allergy 37:1334-9. 2007
    ..Mannose-binding lectin (MBL) is one of the key molecules in complement activation pathways that are associated with several infectious and immune disorders...
  26. ncbi request reprint Genetic polymorphisms in MDR1 and CYP3A5 and MDR1 haplotype in mainland Chinese Han, Uygur and Kazakh ethnic groups
    D Li
    Department of Pharmacology, Basic Medical School, Health Science Center, Beijing Peking University, Beijing, China
    J Clin Pharm Ther 32:89-95. 2007
    ..In this study, we investigated the distribution of MDR1 and CYP3A5 SNPs among mainland Chinese Han, Uygur and Kazakh ethnic groups...
  27. ncbi request reprint MPZL1/PZR, a novel candidate predisposing schizophrenia in Han Chinese
    G He
    Bio X Life Science Research Center, Shanghai Jiao Tong University, Shanghai, PR China
    Mol Psychiatry 11:748-51. 2006
    ..064 x 10(-6)), but no specific transmission distortions. Thus, we propose that the MPZL1/PZR gene may be important in the predisposition to schizophrenia among Han Chinese...
  28. ncbi request reprint Polymorphisms of the DNA repair gene XRCC1 and risk of gastric cancer in a Chinese population
    H Shen
    Department of Epidemiology and Statistics, School of Public Health, Nanjing Medical University, Nanjing, China
    Int J Cancer 88:601-6. 2000
    ..18, 95% CI=1.21-3.94) than individuals with other genotypes. These findings support the hypothesis that these 2 XRCC1 variants may contribute to the risk of developing gastric cancer, particularly gastric cardia cancer...
  29. ncbi request reprint Metabolic gene polymorphisms and risk of dysmenorrhea
    D Wu
    Research Institute for Biomedicine, Anhui Medical University, China
    Epidemiology 11:648-53. 2000
    ..1; 95% CI = 1.2-8.0). This study provides evidence of genetic susceptibility to recurrent dysmenorrhea...
  30. ncbi request reprint Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study
    H Shen
    Department of Epidemiology and Statistics, School of Public Health, Nanjing Medical University, Nanjing, People s Republic of China
    Int J Cancer 95:332-6. 2001
    ..Our findings support the hypothesis that MTHFR C677T variants contribute to gastric carcinogenesis, particularly in gastric cardia. Larger studies incorporating dietary folate intake and serum levels are needed to confirm our findings...
  31. ncbi request reprint Apolipoprotein E gene polymorphism and its association with human longevity in the Uygur nationality in Xinjiang
    X Wang
    Department of Pediatrics, Third Teaching Hospital of Peking University, Beijing 100083, China
    Chin Med J (Engl) 114:817-20. 2001
    ..To study the relationship between apoE alleles and life-span...
  32. ncbi request reprint Mutation in the gene responsible for cystic fibrosis and predisposition to chronic rhinosinusitis in the general population
    X Wang
    McKusick Nathans Institute of Genetic Medicine, CMSC 1004, Baltimore, MD 21287, USA
    JAMA 284:1814-9. 2000
    ..Chronic rhinosinusitis is a consistent feature of the autosomal recessive disorder cystic fibrosis (CF)...
  33. ncbi request reprint Refinement of the locus for autosomal dominant hereditary gingival fibromatosis (GINGF) to a 3.8-cM region on 2p21
    S Xiao
    Shanghai Research Center of Biotechnology, Chinese Academy of Science, Shanghai, 200233, People s Republic of China
    Genomics 68:247-52. 2000
    ..This region overlaps by 3.8 cM with the previously reported HGF region. Single-strand conformation polymorphism and sequence analysis of the coding region of cytochrome P450 1B1 (CYP1B1) excluded it as a likely candidate gene...
  34. ncbi request reprint GNB3 gene C825T and ACE gene I/D polymorphisms in essential hypertension in a Kazakh genetic isolate
    X Wang
    Department of Cardiovasology, 1st Teaching Hospital, Xinjiang Medical University, Urumqi 830054, PR China
    J Hum Hypertens 18:663-8. 2004
    ..In conclusion, the polymorphisms in the GNB3 gene and ACE gene, solely or combined, did not confer a significantly increased risk for the development of EH in the Kazakh isolate of northeast China...
  35. ncbi request reprint Deep vein thrombosis in trauma: a prospective study of lower limb orthopedic trauma patients in Tianjin Hospital, China
    Y Lu
    Tianjin Orthopedic Hospital, Tianjin, China
    Int Angiol 26:165-70. 2007
    ..Our aim was to establish the rate of DVT in orthopedic trauma patients in Tianjin Hospital, to identify DVT risk factors and to support the use of prophylaxis...
  36. ncbi request reprint Compound heterozygosity for two novel mutations (1203insG/Y1456X) in the von Willebrand factor gene causing type 3 von Willebrand disease
    F Xie
    Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiaotong University, Shanghai, China
    Haemophilia 13:645-8. 2007
    ..The failure to amplify VWF cDNA from the patient by semi-nested PCR is consistent with the induction of nonsense-mediated mRNA decay...
  37. ncbi request reprint High expression of nuclear factor of activated T cells in Chinese primary non-small cell lung cancer tissues
    K Zhang
    State Key Laboratory of Genetic Engineering, Department of Biochemistry, School of Life Sciences, Fudan University, Shanghai, China
    Int J Biol Markers 22:221-5. 2007
    ..This research was the first to investigate NFAT protein expression in primary non-small cell lung cancer (NSCLC) tissues from Chinese patients...
  38. pmc Conditional regulation of cyclooxygenase-2 in tracheobronchial epithelial cells modulates pulmonary immunity
    G Y Park
    Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, University of Illinois, Chicago, IL, USA
    Clin Exp Immunol 150:245-54. 2007
    ..COX-2 gene expression in airway epithelial cells has an important role in determining immunological response to infectious and allergic agents...
  39. ncbi request reprint A population-based survey of multiple sclerosis in Shanghai, China
    Q Cheng
    Department of Neurology, Ruijin Hospital, Shanghai, PR China
    Neurology 68:1495-500. 2007
    ..To conduct a large population-based survey on multiple sclerosis (MS) prevalence in Shanghai, China...
  40. ncbi request reprint Factors associated with survival probability in autopsy-proven frontotemporal lobar degeneration
    S X Xie
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine Philadelphia, PA, USA
    J Neurol Neurosurg Psychiatry 79:126-9. 2008
    ..To examine the clinical and pathological factors associated with survival in autopsy-confirmed frontotemporal lobar degeneration (FTLD)...
  41. ncbi request reprint TUB is a candidate gene for late-onset obesity in women
    H Snieder
    Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, P O Box 30 001, 9700 RB, Groningen, The Netherlands
    Diabetologia 51:54-61. 2008
    ..Here, we attempted a replication of these associations in a large population-based cohort of female twins comprehensively phenotyped for measures of general and central obesity...
  42. ncbi request reprint Clostridium perfringens toxin types from freshwater fishes in one water reservoir of Shandong Province of China, determined by PCR
    Y Cai
    College of Animal Science and Veterinary Medicine Shandong Agricultural University, Shandong, China
    Dtsch Tierarztl Wochenschr 115:292-4, 296-7. 2008
    ..The origin of this bacterium and its importance to human food poisoning in freshwater fish is discussed...
  43. doi request reprint M129V polymorphism in the prion protein gene is not associated with mesial temporal lobe epilepsy in a Han Chinese population
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China
    Eur J Neurol 15:827-30. 2008
    ..We screened variations in the open-reading frame (ORF) of the PRNP gene and also replicated the association of the M129V polymorphism with TLE in a Han Chinese population...
  44. doi request reprint The fibroblast growth factor 2 gene is associated with embryonic mortality in cattle
    H Khatib
    Department of Dairy Science, University of Wisconsin, Madison 53706, USA
    J Anim Sci 86:2063-7. 2008
    ..Thus, we propose that FGF2 can be used in animal breeding strategies to test for improved reproductive performance...
  45. ncbi request reprint Clinical features of patients with multiple sclerosis from a survey in Shanghai, China
    Q Cheng
    Department of Neurology, Ruijin Hospital, Medical School of Shanghai Jiao Tong University, Shanghai, China
    Mult Scler 14:671-8. 2008
    ..To describe clinical features of patients with multiple sclerosis (MS) in Shanghai, China...
  46. ncbi request reprint Effect of Xuezhikang, an extract from red yeast Chinese rice, on coronary events in a Chinese population with previous myocardial infarction
    Zongliang Lu
    Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, Peoples Republic of China
    Am J Cardiol 101:1689-93. 2008
    ..In conclusion, long-term therapy with XZK significantly decreased the recurrence of coronary events and the occurrence of new CV events and deaths, improved lipoprotein regulation, and was safe and well tolerated...
  47. pmc Id-1 and Id-2 are markers for metastasis and prognosis in oesophageal squamous cell carcinoma
    H F Yuen
    Department of Pathology, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China
    Br J Cancer 97:1409-15. 2007
    ..Our results suggest that Id-1 may promote distant metastasis in ESCC, and both Id-1 and Id-2 may be used for prognostication for ESCC patients...
  48. ncbi request reprint Response to pioglitazone treatment is associated with the lipoprotein lipase S447X variant in subjects with type 2 diabetes mellitus
    G Wang
    Department of Endocrinology, Peking University Third Hospital, Beijing, China
    Int J Clin Pract 61:552-7. 2007
    ..Moreover, pioglitazone treatment has significantly beneficial effects on serum lipid profile and blood pressure in S447S genotype carriers. The S447X variant in LPL gene may be a cause for therapy modification by pioglitazone...
  49. ncbi request reprint A Chinese isolate of barley yellow dwarf virus-PAV represents a third distinct species within the PAV serotype
    F Liu
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
    Arch Virol 152:1365-73. 2007
    ..These data suggest that PAV-CN may have undergone a recombination event with GAV and that PAV-CN represents a third distinct species within the PAV serotype of BYDV...
  50. ncbi request reprint [Study on polymorphism of human leukocyte antigen I in patients with endometriosis]
    X Wang
    Department of Obstetrics and Gynecology, Second Affiliated Hospital, Hunan Medical University, Changsha 410011, China
    Zhonghua Fu Chan Ke Za Zhi 36:150-2. 2001
    ..05, RR 0.1346) as compared with those of the controls. CONCLUSIONS: The occurrence of Em may be associated with the presence of HLA-I B46 antigen. On the contrary, the HLA-I B48 antigen might play a protective role against Em...
  51. ncbi request reprint [The study on human leucocyte antigen DQ region genes polymorphism in unexplained habitual abortion patients]
    Q Lin
    Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China
    Zhonghua Fu Chan Ke Za Zhi 36:293-5. 2001
    ..To investigate whether human leucocyte antigen DQ (HLA-DQ) genes polymorphism are related to the susceptibility to unexplained habitual abortion...
  52. ncbi request reprint [The polymorphism of (CAG)n repeats within androgen receptor gene among Chinese male population]
    G Wang
    Department of Pathophysiology, The Second Military Medical University, Shanghai, 200433 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 18:456-8. 2001
    ..To investigate the polymorphism of (CAG)n repeats within androgen receptor (AR) gene among normal Chinese male population...
  53. ncbi request reprint Study of the distribution of non-point source pollution in the watershed of the Miyun Reservoir, Beijing, China
    X Wang
    Department of Geography, Capital Normal University, Beijing, PR China
    Water Sci Technol 44:35-40. 2001
    ..However, due to the variability of land use areas, agricultural land contributes the greatest amount of TP and forestry lands the greatest amount of TN...
  54. ncbi request reprint Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia
    M Mehrabian
    Department of Medicine, University of California, Los Angeles, USA
    Circ Res 89:125-30. 2001
    ..The locus contains the candidate gene peroxisome proliferator-activated receptor-gamma, and the congenic mice exhibited significantly reduced expression of peroxisome proliferator-activated receptor-gamma...
  55. ncbi request reprint An intronic poly (AT) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck: a case-control study
    H Shen
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Res 61:3321-5. 2001
    ..333, 0.281, 0.296, and 0.353, respectively). The case-control findings support the hypothesis that the XPC-PAT+ allele may contribute to the risk of developing SCCHN...
  56. ncbi request reprint Lack of association between alpha2-macroglobulin polymorphisms and Alzheimer's disease
    X Wang
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    Hum Genet 108:105-8. 2001
    ..In conclusion, we observed no association between either the intronic deletion polymorphism or the Ile1000Val polymorphism of A2M and AD in our case-control cohort...
  57. pmc The LIM/double zinc-finger motif functions as a protein dimerization domain
    R Feuerstein
    Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia 19104 6145
    Proc Natl Acad Sci U S A 91:10655-9. 1994
    ..These observations support a specific role for protein dimerization in the function of proteins containing the LIM/double zinc-finger domain and expand the general spectrum of potential interactions mediated by zinc-finger motifs...
  58. ncbi request reprint The relationship of angiotensin-converting enzyme gene to essential hypertension and drug treatment in Chongqing
    Q Liu
    Department of Core Laboratory and Department of Cardiology, The First Affiliated Hospital of Chongqing University of Medical Sciences, Chongqing, 400016 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 17:340-2. 2000
    ..To measure and discuss the association of the angiotensin converting enzyme (ACE) gene insertion/deletion(I/D) polymorphism with essential hypertension and drug treatment in Chongqing...
  59. ncbi request reprint Nested chromosomal deletions induced with retroviral vectors in mice
    H Su
    Program in Developmental Biology, Department of Molecular Genetics, Baylor College of Medicine, Houston, Texas, USA
    Nat Genet 24:92-5. 2000
    ..Our approach can be extended to any region of the mouse genome...
  60. ncbi request reprint Transfection of p53-knockout mouse fibroblasts with wild-type p53 increases the thermosensitivity and stimulates apoptosis induced by heat stress
    H Matsumoto
    Department of Biology, Nara Medical University, Kashihara, Japan
    Int J Radiat Oncol Biol Phys 38:1089-95. 1997
    ..The relationship between p53 functions and cellular thermosensitivity was evaluated using murine fibroblasts transfected with either wild-type p53 or mutated p53, or those with a null p53 genotype...
  61. ncbi request reprint [Colon cancer risk factors in Jiashan county, Zhejiang province, the highest incidence area in China]
    X Wang
    Zhejiang Cancer Institute, Hangzhou 310022, China
    Zhonghua Zhong Liu Za Zhi 23:480-2. 2001
    ..Psychological depression, inheritance and lower digestive tract diseases were also correlated with colon cancer...
  62. ncbi request reprint Nucleotide sequences of the coat protein and readthrough protein genes of the Chinese GAV isolate of barley yellow dwarf virus
    X Wang
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing
    Acta Virol 45:249-52. 2001
    ..8%). The results of the alignment of the deduced amino acid sequences of RTP showed that the sequence diversity observed was located at the C terminus...
  63. ncbi request reprint Cytokine manipulation of explanted Dupuytren's affected human palmar fascia
    M A Kuhn
    Institute of Tissue Regeneration Repair and Rehabilitation, Department of Veterans Affairs Medical Center, Bay Pines, FL 33744, USA
    Int J Surg Investig 2:443-56. 2001
    ..CONCLUSION: These findings paralleled those from other fibroproliferative disorders suggesting a role for TGFbeta2 in the pathogenesis of Dupuytren's contracture as well as possible novel treatment approaches...
  64. pmc SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women
    Y Jamshidi
    Nutrition Food and Health Research Centre, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
    Atherosclerosis 194:e26-33. 2007
    ..009). Association of single tSNPs with both apoB and LDL cholesterol as well as interactions between the two genes suggest that variants influencing SHP-2 activity may modulate the acute pathway by which insulin regulates these lipids...
  65. ncbi request reprint Multi-class cancer classification using multinomial probit regression with Bayesian gene selection
    X Zhou
    Department of Electrical Engineering, Texas A and M University, College Station, TX 77843, USA
    Syst Biol (Stevenage) 153:70-8. 2006
    ..Also, the strongest genes selected using our methods are consistent with the biological significance. The recognition accuracies are very high using our proposed methods...
  66. ncbi request reprint Molecular variability of the coat protein gene of Potato virus Y from tobacco in China
    N Li
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing
    Acta Virol 50:107-13. 2006
    ..6%. The highest identity was observed in the C-terminal half of the CP protein, where only 11 amino acid differences could be observed, in contrast to the N-terminal half with 22 differences...
  67. pmc Comparison of linkage disequilibrium patterns between the HapMap CEPH samples and a family-based cohort of Northern European descent
    E M Smith
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Genomics 88:407-14. 2006
    ..8 in the disease cohort. This confirms the usefulness of the CEPH cohort of the HapMap as a reference sample for further investigations into the genomic variation of populations of Northern European descent...
  68. ncbi request reprint Egr-1 transcription activation exists in placental endothelium when vascular disease is present
    X Wang
    Department of Obstetrics and Gynaecology, University of Sydney at Westmead Hospital, Sydney, New South Wales, Australia
    BJOG 113:683-7. 2006
    ....
  69. pmc Common polymorphisms in SOCS3 are not associated with body weight, insulin sensitivity or lipid profile in normal female twins
    Y Jamshidi
    Department of Clinical Developmental Sciences, St George s, University of London, London, UK
    Diabetologia 49:306-10. 2006
    ....
  70. ncbi request reprint Municipal wastewater treatment with pond-constructed wetland system: a case study
    X Wang
    School of Environmental Science and Engineering, Shanghai Jiaotong University, 800 Dongchuan Rd, Shanghai, 200240, China
    Water Sci Technol 51:325-9. 2005
    ..A possible reason is the low dissolved oxygen concentration in the wetland. Constructed wetlands can restrain the growth of algae effectively, and can produce obvious ecological and economical benefits...
  71. ncbi request reprint Older people in China and the United Kingdom differ in the relationships among parathyroid hormone, vitamin D, and bone mineral status
    L Yan
    Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
    Bone 33:620-7. 2003
    ..2 (0.08), P = 0.02]. These data suggest that although PTH increases when 25OH-D decreases, and Chinese people have a higher PTH for a given 25OH-D, older Chinese adults may be more resistant than Britons to the effects of PTH on bone...
  72. ncbi request reprint Molecular analysis of multiple cytochrome P450 genes from the malaria vector, Anopheles gambiae
    H Ranson
    Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA
    Insect Mol Biol 11:409-18. 2002
    ..Eighteen new A. gambiae Cyp4 P450 genes were identified using degenerate PCR primers, cDNAs were detected for ten and in situ locations for thirteen members of this gene family...
  73. ncbi request reprint [A study for the relationship between serum calcitonin gene-related peptide and coronary arteriopathy]
    Z Wang
    Department of Emergency, Third Hospital of Peking University Beijing 100083, China
    Zhonghua Nei Ke Za Zhi 40:750-2. 2001
    ..CONCLUSIONS: It is shown that aging, smoking and diabetes are all independent risk factors for the development of angiopathy, while CGRP is an independent protective factor for the development of coronary angiopathy...
  74. pmc Prenylated isoforms of yeast casein kinase I, including the novel Yck3p, suppress the gcs1 blockage of cell proliferation from stationary phase
    X Wang
    Department of Biochemistry, Dalhousie University, Halifax, Nova Scotia, Canada
    Mol Cell Biol 16:5375-85. 1996
    ..The ability of an increased casein kinase I gene dosage to suppress the effects caused by the absence of Gcs1p suggests that Gcs1p and Yck1p-Yck2p affect parallel pathways...