Philip Trackman


Affiliation: Boston University
Country: USA


  1. Trackman P. Diverse biological functions of extracellular collagen processing enzymes. J Cell Biochem. 2005;96:927-37 pubmed
    ..An emerging concept is that a dynamic interplay exists between extracellular products and byproducts with cells that helps to maintain normal cellular phenotypes and tissue integrity. ..
  2. Trackman P, Kantarci A. Connective tissue metabolism and gingival overgrowth. Crit Rev Oral Biol Med. 2004;15:165-75 pubmed
  3. Trackman P, Kantarci A. Molecular and clinical aspects of drug-induced gingival overgrowth. J Dent Res. 2015;94:540-6 pubmed publisher
  4. Trackman P. An interesting perspective on a well-studied pathway: does type III TGF-Î’ receptor have therapeutic potential?. J Cell Commun Signal. 2015;9:103 pubmed publisher
    ..The type III TGF-β receptor has potential therapeutic and prognostic potential in breast cancer. ..
  5. Assaggaf M, Kantarci A, Sume S, Trackman P. Prevention of phenytoin-induced gingival overgrowth by lovastatin in mice. Am J Pathol. 2015;185:1588-99 pubmed publisher
    ..Findings suggest that statins may serve to prevent or attenuate phenytoin-induced human gingival overgrowth, although specific human studies are required. ..
  6. Ozdener G, Bais M, Trackman P. Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide. Mol Oncol. 2016;10:1-23 pubmed publisher
  7. Alsulaiman M, Bais M, Trackman P. Lysyl oxidase propeptide stimulates osteoblast and osteoclast differentiation and enhances PC3 and DU145 prostate cancer cell effects on bone in vivo. J Cell Commun Signal. 2016;10:17-31 pubmed publisher
    ..rLOX-PP may serve to enhance coupling interactions between osteoclasts and osteoblasts helping to maintain a normal bone turnover in health, while contributing to bone abnormalities in disease. ..
  8. Trackman P. Enzymatic and non-enzymatic functions of the lysyl oxidase family in bone. Matrix Biol. 2016;52-54:7-18 pubmed publisher
  9. Trackman P, Saxena D, Bais M. TGF-β1- and CCN2-Stimulated Sirius Red Assay for Collagen Accumulation in Cultured Cells. Methods Mol Biol. 2017;1489:481-485 pubmed

More Information


  1. Trackman P, Bais M. Measurement of lysyl oxidase activity from small tissue samples and cell cultures. Methods Cell Biol. 2018;143:147-156 pubmed publisher
  2. Trackman P. Functional importance of lysyl oxidase family propeptide regions. J Cell Commun Signal. 2018;12:45-53 pubmed publisher
    ..Although much has been learned, there is a need for greater attention to structure/function relationships and mechanisms to more fully understand these multifunctional proteins. ..
  3. Alsofi L, Daley E, Hornstra I, Morgan E, Mason Z, Acevedo J, et al. Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice. Calcif Tissue Int. 2016;98:172-85 pubmed publisher
    ..Data indicate that LOXL1-/- mutant mice develop appendicular and axial skeletal phenotypes characterized by decreased bone volume fraction and compromised trabecular microstructure, predominantly in females. ..