Research Topics
Species | Jolyon TerragniSummaryAffiliation: Boston University Country: USA Publications
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Publications
Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factorsJolyon Terragni
Department of Biology, Boston University, Boston MA 02215, USA
BMC Cell Biol 9:6. 2008....
The E-box binding factors Max/Mnt, MITF, and USF1 act coordinately with FoxO to regulate expression of proapoptotic and cell cycle control genes by phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3 signalingJolyon Terragni
Department of Biology, Boston University, Boston, Massachusetts 02215, USA
J Biol Chem 286:36215-27. 2011..These results define a novel E-box-regulated network that functions coordinately with FoxO to regulate transcription of apoptotic and cell cycle regulatory genes downstream of PI 3-kinase/Akt/GSK3 signaling...
mRNA degradation plays a significant role in the program of gene expression regulated by phosphatidylinositol 3-kinase signalingJulie R Graham
Department of Biology, Boston University, Boston, Massachusetts 02215, USA
Mol Cell Biol 30:5295-305. 2010..These results show that PI 3-kinase regulation of mRNA stability, predominantly mediated by BRF1, plays a major role in regulating gene expression...
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpointsBing Ren
Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
Genes Dev 16:245-56. 2002..Our data indicate that E2F directly links cell cycle progression with the coordinate regulation of genes essential for both the synthesis of DNA as well as its surveillance...
