Affiliation: Boston University
- Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epitheliumSriram Sridhar
Pulmonary Center, Boston University School of Medicine, Albany Street, Boston Massachusetts, USA
BMC Genomics 9:259. 2008..In this study, we explored relationships in whole-genome gene expression between extrathorcic (buccal and nasal) and intrathoracic (bronchial) epithelium in healthy current and never smokers...
- The field of tissue injury in the lung and airwayKatrina Steiling
The Pulmonary Center, Boston University Medical Center, Boston, Massachusetts 02118, USA
Cancer Prev Res (Phila) 1:396-403. 2008....
- Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokersKatrina Steiling
The Pulmonary Center, Boston University Medical Center, Boston, Massachusetts, United States of America
PLoS ONE 4:e5043. 2009....
- Airway gene expression in chronic obstructive pulmonary diseaseKatrina Steiling
The Pulmonary Center, Boston University Medical Center, 72 East Concord Street R 304, Boston, MA 02118
Proc Am Thorac Soc 6:697-700. 2009....
- A prediction model for lung cancer diagnosis that integrates genomic and clinical featuresJennifer Beane
The Pulmonary Center, Boston University Medical Center, Boston, MA 02118, USA
Cancer Prev Res (Phila) 1:56-64. 2008..These findings suggest that use of the clinicogenomic model may expedite more invasive testing and definitive therapy for smokers with lung cancer and reduce invasive diagnostic procedures for individuals without lung cancer...
- Transcriptomic studies of the airway field of injury associated with smoking-related lung diseaseAdam C Gower
Boston University School of Medicine, Boston, MA 02118, USA
Proc Am Thorac Soc 8:173-9. 2011....
- Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancerAvrum Spira
The Pulmonary Center, Boston University Medical Center, 715 Albany Street, Boston, Massachusetts 02118, USA
Nat Med 13:361-6. 2007..These findings indicate that gene expression in cytologically normal large-airway epithelial cells can serve as a lung cancer biomarker, potentially owing to a cancer-specific airway-wide response to cigarette smoke...
- A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairmentKatrina Steiling
Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA 02118, USA
Am J Respir Crit Care Med 187:933-42. 2013..Molecular phenotyping of chronic obstructive pulmonary disease (COPD) has been impeded in part by the difficulty in obtaining lung tissue samples from individuals with impaired lung function...
- Interaction of cigarette exposure and airway epithelial cell gene expressionJerome S Brody
Pulmonary Center, Boston University School of Medicine, Massachusetts 02218, USA
Annu Rev Physiol 73:437-56. 2011....