Dimitrije Stamenovic

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint Invited review: engineering approaches to cytoskeletal mechanics
    D Stamenovic
    Department of Biomedical Engineering, Boston University, Boston Massachusetts 02215, USA
    J Appl Physiol 89:2085-90. 2000
  2. ncbi request reprint Cell prestress. II. Contribution of microtubules
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Am J Physiol Cell Physiol 282:C617-24. 2002
  3. ncbi request reprint Effect of the cytoskeletal prestress on the mechanical impedance of cultured airway smooth muscle cells
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
    J Appl Physiol 92:1443-50. 2002
  4. ncbi request reprint Microtubules may harden or soften cells, depending of the extent of cell distension
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street Boston, MA 02215, USA
    J Biomech 38:1728-32. 2005
  5. ncbi request reprint Models of cytoskeletal mechanics of adherent cells
    D Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Biomech Model Mechanobiol 1:95-108. 2002
  6. ncbi request reprint Rheology of airway smooth muscle cells is associated with cytoskeletal contractile stress
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington St, Boston, MA 02215, USA
    J Appl Physiol 96:1600-5. 2004
  7. ncbi request reprint Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells
    Ning Wang
    Physiology Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Physiol Cell Physiol 282:C606-16. 2002
  8. ncbi request reprint Distending stress of the cytoskeleton is a key determinant of cell rheological behavior
    Noah Rosenblatt
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Biochem Biophys Res Commun 321:617-22. 2004
  9. ncbi request reprint Experimental tests of the cellular tensegrity hypothesis
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Biorheology 40:221-5. 2003
  10. ncbi request reprint Dynamics of prestressed semiflexible polymer chains as a model of cell rheology
    Noah Rosenblatt
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Phys Rev Lett 97:168101. 2006

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Invited review: engineering approaches to cytoskeletal mechanics
    D Stamenovic
    Department of Biomedical Engineering, Boston University, Boston Massachusetts 02215, USA
    J Appl Physiol 89:2085-90. 2000
    ..This review focuses on engineering approaches that have been used in the past two decades in studies of the mechanics of the CSK...
  2. ncbi request reprint Cell prestress. II. Contribution of microtubules
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Am J Physiol Cell Physiol 282:C617-24. 2002
    ..This is further evidence supporting the idea that MTs are intracellular compression-bearing elements...
  3. ncbi request reprint Effect of the cytoskeletal prestress on the mechanical impedance of cultured airway smooth muscle cells
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
    J Appl Physiol 92:1443-50. 2002
    ....
  4. ncbi request reprint Microtubules may harden or soften cells, depending of the extent of cell distension
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street Boston, MA 02215, USA
    J Biomech 38:1728-32. 2005
    ..Since in their natural habitat cells seldom exhibit highly spread forms, the above results suggest that the contribution of microtubules to cell deformability cannot be overlooked...
  5. ncbi request reprint Models of cytoskeletal mechanics of adherent cells
    D Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Biomech Model Mechanobiol 1:95-108. 2002
    ..We concluded that stress-supported structures appear more suitable for describing cell deformability because this class of structures can explain the central role that the cytoskeletal contractile prestress plays in cellular mechanics...
  6. ncbi request reprint Rheology of airway smooth muscle cells is associated with cytoskeletal contractile stress
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington St, Boston, MA 02215, USA
    J Appl Physiol 96:1600-5. 2004
    ....
  7. ncbi request reprint Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells
    Ning Wang
    Physiology Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Physiol Cell Physiol 282:C606-16. 2002
    ..Regardless of mechanism, these data establish a strong association between stiffness of HASM cells and the level of tensile stress within the cytoskeleton...
  8. ncbi request reprint Distending stress of the cytoskeleton is a key determinant of cell rheological behavior
    Noah Rosenblatt
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Biochem Biophys Res Commun 321:617-22. 2004
    ..These findings provide strong evidence that the cytoskeletal distending stress is a key determinant of cell rheological properties...
  9. ncbi request reprint Experimental tests of the cellular tensegrity hypothesis
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Biorheology 40:221-5. 2003
    ..However, they do support a priori predictions of tensegrity. As such, it may not be necessary to invoke more complex mechanisms to explain these central features of cell deformability...
  10. ncbi request reprint Dynamics of prestressed semiflexible polymer chains as a model of cell rheology
    Noah Rosenblatt
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Phys Rev Lett 97:168101. 2006
    ..These results indicate that the main aspects of cell rheology are consistent with the dynamics of single polymer chains under tension...
  11. ncbi request reprint A computational tensegrity model predicts dynamic rheological behaviors in living cells
    Cornel Sultan
    Vascular Biology Program, Department of Pathology, Children s Hospital Harvard Medical School, Boston, MA 02115, USA
    Ann Biomed Eng 32:520-30. 2004
    ....
  12. ncbi request reprint Contributions of the active and passive components of the cytoskeletal prestress to stiffening of airway smooth muscle cells
    Noah Rosenblatt
    Department of Biomedical Engineering, Boston University, 44 Cummington St, Boston, MA 02215, USA
    Ann Biomed Eng 35:224-34. 2007
    ....
  13. ncbi request reprint Power-law creep behavior of a semiflexible chain
    Arnab Majumdar
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 78:041922. 2008
    ..These results indicate that the essential features of cellular rheology can be explained by the viscoelastic behaviors of individual semiflexible polymers of the cytoskeleton...
  14. doi request reprint Cytoskeletal mechanics in airway smooth muscle cells
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Respir Physiol Neurobiol 163:25-32. 2008
    ....
  15. ncbi request reprint Viscoelastic and dynamic nonlinear properties of airway smooth muscle tissue: roles of mechanical force and the cytoskeleton
    Satoru Ito
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Am J Physiol Lung Cell Mol Physiol 290:L1227-37. 2006
    ....
  16. pmc Rheological behavior of living cells is timescale-dependent
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, and Department of Pathology, Children s Hospital, Boston, Massachusetts, USA
    Biophys J 93:L39-41. 2007
    ....
  17. pmc Fluidization, resolidification, and reorientation of the endothelial cell in response to slow tidal stretches
    Ramaswamy Krishnan
    Center for Vascular Biology Research, Harvard Medical School, Boston, Massachusetts, USA
    Am J Physiol Cell Physiol 303:C368-75. 2012
    ....
  18. pmc A zipper network model of the failure mechanics of extracellular matrices
    Michael C Ritter
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 106:1081-6. 2009
    ..This study reveals a role for PGs in the failure properties of engineered and native ECM with implications for the design of engineered tissues...
  19. pmc A micropatterning and image processing approach to simplify measurement of cellular traction forces
    Samuel R Polio
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Acta Biomater 8:82-8. 2012
    ....
  20. ncbi request reprint Effects of cytoskeletal prestress on cell rheological behavior
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Acta Biomater 1:255-62. 2005
    ....
  21. ncbi request reprint Biomechanics of the lung parenchyma: critical roles of collagen and mechanical forces
    Bela Suki
    Department of Biomedical Engineering, Boston University, 44 Cummington St, Boston, MA 02215, USA
    J Appl Physiol 98:1892-9. 2005
    ....
  22. ncbi request reprint Physiology: Dynamic instabilities in the inflating lung
    Adriano M Alencar
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
    Nature 417:809-11. 2002
    ..Our analysis of this apparent thermodynamic paradox provides a better understanding of aeration in the deep regions of the lung, which may find application in medical conditions in which gas exchange is impaired...
  23. ncbi request reprint Contractile torque as a steering mechanism for orientation of adherent cells
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA
    Mech Chem Biosyst 2:69-76. 2005
    ..Model predictions are tested in the case of simple elongation of the substrate and found to be consistent with experimental data from the literature...
  24. doi request reprint Lung parenchymal mechanics
    Bela Suki
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA
    Compr Physiol 1:1317-51. 2011
    ..An integrated view of lung mechanics is presented and the utility of parenchymal mechanics at the bedside as well as its possible future role in lung physiology and medicine are discussed...
  25. doi request reprint Stress transmission within the cell
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, Boston, USA
    Compr Physiol 1:499-524. 2011
    ..It is anticipated that advances in cell mechanics will help developing novel therapeutics to treat pulmonary diseases like asthma, pulmonary fibrosis, and chronic obstructive pulmonary disease...
  26. doi request reprint Pneumatic osteoarthritis knee brace
    Dimitrije Stamenovic
    Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    J Biomech Eng 131:045001. 2009
    ..Using a finite-element analysis, we show that with a moderate level of applied pressure, this pneumatic brace can, in theory, counterbalance a greater fraction of external adduction moment than the currently existing braces...