Nadia Solovieff

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi Ancestry of African Americans with sickle cell disease
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Blood Cells Mol Dis 47:41-5. 2011
  2. ncbi Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method
    Gina M Peloso
    Department of Biostatistics, Boston University School of Public Heath, Crosstown Center, 801 Massachusetts Avenue, 3rd Floor, Boston, Massachusetts 02118 USA
    BMC Proc 3:S108. 2009
  3. ncbi Imputation of missing genotypes: an empirical evaluation of IMPUTE
    Zhenming Zhao
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston MA 02118, USA
    BMC Genet 9:85. 2008
  4. ncbi Clustering by genetic ancestry using genome-wide SNP data
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    BMC Genet 11:108. 2010
  5. ncbi Genetic signatures of exceptional longevity in humans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e29848. 2012
  6. ncbi Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    Am J Hematol 85:29-35. 2010
  7. ncbi Genetic signatures of exceptional longevity in humans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Science 2010:. 2010
  8. ncbi A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia
    Jacqueline N Milton
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e34741. 2012
  9. ncbi Severe sickle cell anemia is associated with increased plasma levels of TNF-R1 and VCAM-1
    Daniel A Dworkis
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    Am J Hematol 86:220-3. 2011
  10. ncbi Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, MA, USA
    Blood 115:1815-22. 2010

Collaborators

Detail Information

Publications13

  1. ncbi Ancestry of African Americans with sickle cell disease
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Blood Cells Mol Dis 47:41-5. 2011
    ....
  2. ncbi Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method
    Gina M Peloso
    Department of Biostatistics, Boston University School of Public Heath, Crosstown Center, 801 Massachusetts Avenue, 3rd Floor, Boston, Massachusetts 02118 USA
    BMC Proc 3:S108. 2009
    ....
  3. ncbi Imputation of missing genotypes: an empirical evaluation of IMPUTE
    Zhenming Zhao
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston MA 02118, USA
    BMC Genet 9:85. 2008
    ....
  4. ncbi Clustering by genetic ancestry using genome-wide SNP data
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    BMC Genet 11:108. 2010
    ..An alternative solution is genetic matching of cases and controls that requires, however, well defined population strata for appropriate selection of cases and controls...
  5. ncbi Genetic signatures of exceptional longevity in humans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e29848. 2012
    ..The correlation between 3 signatures and 3 different life spans was replicated in the combined replication sets. The different signatures may help dissect this complex phenotype into sub-phenotypes of exceptional longevity...
  6. ncbi Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    Am J Hematol 85:29-35. 2010
    ..Additional validation, resequencing, and functional studies to understand the biology and reveal mechanisms by which candidate genes might have their effects are the future goals of this work...
  7. ncbi Genetic signatures of exceptional longevity in humans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Science 2010:. 2010
    ..g., dementia, hypertension, and cardiovascular disease) and may help dissect this complex phenotype into subphenotypes of healthy aging...
  8. ncbi A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia
    Jacqueline N Milton
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e34741. 2012
    ..15 × 10(-4)). These results confirm that the UGT1A region is the major regulator of bilirubin metabolism in African Americans with sickle cell anemia, similar to what is observed in other ethnicities...
  9. ncbi Severe sickle cell anemia is associated with increased plasma levels of TNF-R1 and VCAM-1
    Daniel A Dworkis
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    Am J Hematol 86:220-3. 2011
    ....
  10. ncbi Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, MA, USA
    Blood 115:1815-22. 2010
    ..6E-21) and in Thailand and Hong Kong subjects. Elements within the olfactory receptor gene cluster might play a regulatory role in gamma-globin gene expression...
  11. ncbi Fetal hemoglobin in sickle cell anemia
    Idowu Akinsheye
    Department of Medicine, Boston University School of Medicine, Boston, MA, USA
    Blood 118:19-27. 2011
    ..Recent insights into HbF regulation have spurred new efforts to induce high HbF levels in sickle cell disease beyond those achievable with the current limited repertory of HbF inducers...
  12. ncbi RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 4:e8210. 2009
    ..The majority of genes found thus far to be associated with longevity primarily function in lipoprotein metabolism and insulin/IGF-1 signaling. There are likely many more genetic modifiers of human longevity that remain to be discovered...
  13. ncbi Naïve Bayesian Classifier and Genetic Risk Score for Genetic Risk Prediction of a Categorical Trait: Not so Different after all!
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health Boston, MA, USA
    Front Genet 3:26. 2012
    ..In addition, we study the properties of the two approaches and describe how they can be generalized to include various models of inheritance...