Nadia Solovieff

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Ancestry of African Americans with sickle cell disease
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Blood Cells Mol Dis 47:41-5. 2011
  2. pmc Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method
    Gina M Peloso
    Department of Biostatistics, Boston University School of Public Heath, Crosstown Center, 801 Massachusetts Avenue, 3rd Floor, Boston, Massachusetts 02118 USA
    BMC Proc 3:S108. 2009
  3. pmc Imputation of missing genotypes: an empirical evaluation of IMPUTE
    Zhenming Zhao
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston MA 02118, USA
    BMC Genet 9:85. 2008
  4. pmc Clustering by genetic ancestry using genome-wide SNP data
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    BMC Genet 11:108. 2010
  5. pmc Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans
    Idowu Akinsheye
    Division of Hematology Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA, USA
    Am J Hematol 87:217-9. 2012
  6. pmc Genetic signatures of exceptional longevity in humans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e29848. 2012
  7. pmc Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    Am J Hematol 85:29-35. 2010
  8. doi request reprint Genetic signatures of exceptional longevity in humans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Science 2010:. 2010
  9. pmc A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia
    Jacqueline N Milton
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e34741. 2012
  10. pmc Severe sickle cell anemia is associated with increased plasma levels of TNF-R1 and VCAM-1
    Daniel A Dworkis
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    Am J Hematol 86:220-3. 2011

Collaborators

Detail Information

Publications16

  1. pmc Ancestry of African Americans with sickle cell disease
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Blood Cells Mol Dis 47:41-5. 2011
    ....
  2. pmc Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method
    Gina M Peloso
    Department of Biostatistics, Boston University School of Public Heath, Crosstown Center, 801 Massachusetts Avenue, 3rd Floor, Boston, Massachusetts 02118 USA
    BMC Proc 3:S108. 2009
    ....
  3. pmc Imputation of missing genotypes: an empirical evaluation of IMPUTE
    Zhenming Zhao
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston MA 02118, USA
    BMC Genet 9:85. 2008
    ....
  4. pmc Clustering by genetic ancestry using genome-wide SNP data
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    BMC Genet 11:108. 2010
    ..An alternative solution is genetic matching of cases and controls that requires, however, well defined population strata for appropriate selection of cases and controls...
  5. pmc Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans
    Idowu Akinsheye
    Division of Hematology Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA, USA
    Am J Hematol 87:217-9. 2012
    ..Thirty-eight SNPs were found. Four SNPs had significantly higher major allele frequencies in the unusually high HbF group. In silico analyses of these four polymorphisms predicted alteration in transcription factor binding sites in 3...
  6. pmc Genetic signatures of exceptional longevity in humans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e29848. 2012
    ..The correlation between 3 signatures and 3 different life spans was replicated in the combined replication sets. The different signatures may help dissect this complex phenotype into sub-phenotypes of exceptional longevity...
  7. pmc Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    Am J Hematol 85:29-35. 2010
    ..Additional validation, resequencing, and functional studies to understand the biology and reveal mechanisms by which candidate genes might have their effects are the future goals of this work...
  8. doi request reprint Genetic signatures of exceptional longevity in humans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Science 2010:. 2010
    ..g., dementia, hypertension, and cardiovascular disease) and may help dissect this complex phenotype into subphenotypes of healthy aging...
  9. pmc A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia
    Jacqueline N Milton
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e34741. 2012
    ..15 × 10(-4)). These results confirm that the UGT1A region is the major regulator of bilirubin metabolism in African Americans with sickle cell anemia, similar to what is observed in other ethnicities...
  10. pmc Severe sickle cell anemia is associated with increased plasma levels of TNF-R1 and VCAM-1
    Daniel A Dworkis
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    Am J Hematol 86:220-3. 2011
    ....
  11. pmc Fetal hemoglobin in sickle cell anemia: Genetic studies of the Arab-Indian haplotype
    Duyen Ngo
    Center of Excellence in Sickle Cell Disease, Department of Medicine, Boston University School of Medicine, Boston, MA, USA Electronic address
    Blood Cells Mol Dis 51:22-6. 2013
    ..These regulatory elements, which remain to be discovered, might be specific in the Saudi and some other populations where HbF levels are especially high...
  12. pmc Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster
    Nadia Solovieff
    Department of Biostatistics, Boston University School of Public Health, MA, USA
    Blood 115:1815-22. 2010
    ..6E-21) and in Thailand and Hong Kong subjects. Elements within the olfactory receptor gene cluster might play a regulatory role in gamma-globin gene expression...
  13. pmc Fetal hemoglobin in sickle cell anemia
    Idowu Akinsheye
    Department of Medicine, Boston University School of Medicine, Boston, MA, USA
    Blood 118:19-27. 2011
    ..Recent insights into HbF regulation have spurred new efforts to induce high HbF levels in sickle cell disease beyond those achievable with the current limited repertory of HbF inducers...
  14. pmc RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 4:e8210. 2009
    ..The majority of genes found thus far to be associated with longevity primarily function in lipoprotein metabolism and insulin/IGF-1 signaling. There are likely many more genetic modifiers of human longevity that remain to be discovered...
  15. pmc The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity
    Mark W Logue
    Biomedical Genetics, Department of Medicine, Boston University School of Medicine, Boston, MA, United States Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States
    Psychoneuroendocrinology 38:2249-57. 2013
    ....
  16. pmc Naïve Bayesian Classifier and Genetic Risk Score for Genetic Risk Prediction of a Categorical Trait: Not so Different after all!
    Paola Sebastiani
    Department of Biostatistics, Boston University School of Public Health Boston, MA, USA
    Front Genet 3:26. 2012
    ..In addition, we study the properties of the two approaches and describe how they can be generalized to include various models of inheritance...