Jean Jacques Soghomonian

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi Effects of age on axon terminals forming axosomatic and axodendritic inhibitory synapses in prefrontal cortex
    J J Soghomonian
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Neuroscience 168:74-81. 2010
  2. ncbi L-DOPA-induced dyskinesia in adult rats with a unilateral 6-OHDA lesion of dopamine neurons is paralleled by increased c-fos gene expression in the subthalamic nucleus
    Jean Jacques Soghomonian
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Eur J Neurosci 23:2395-403. 2006
  3. ncbi Dual effects of intermittent or continuous L-DOPA administration on gene expression in the globus pallidus and subthalamic nucleus of adult rats with a unilateral 6-OHDA lesion
    Kirsten M Nielsen
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Synapse 49:246-60. 2003
  4. ncbi Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications
    Jane Yip
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany St, R1003, Boston, MA 02118, USA
    Acta Neuropathol 113:559-68. 2007
  5. ncbi Increased GAD67 mRNA expression in cerebellar interneurons in autism: implications for Purkinje cell dysfunction
    Jane Yip
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci Res 86:525-30. 2008
  6. ncbi Decreased glutamic acid decarboxylase mRNA expression in prefrontal cortex in Parkinson's disease
    Amélie C Lanoue
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts, 02118, USA
    Exp Neurol 226:207-17. 2010
  7. ncbi Subchronic administration of L-DOPA to adult rats with a unilateral 6-hydroxydopamine lesion of dopamine neurons results in a sensitization of enhanced GABA release in the substantia nigra, pars reticulata
    Noriko Yamamoto
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Room L1001, Boston, MA 02118, USA
    Brain Res 1123:196-200. 2006
  8. ncbi Haloperidol treatment after high-dose methamphetamine administration is excitotoxic to GABA cells in the substantia nigra pars reticulata
    Theo Hatzipetros
    Laboratory of Neurochemistry, Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci 27:5895-902. 2007
  9. ncbi High-dose methamphetamine acutely activates the striatonigral pathway to increase striatal glutamate and mediate long-term dopamine toxicity
    Karla A Mark
    Laboratory of Neurochemistry, Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci 24:11449-56. 2004
  10. ncbi Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study
    Jane Yip
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Autism Res 2:50-9. 2009

Research Grants

  1. Behavioral Sensitization and Parkinson's Disease
    Jean Jacques Soghomonian; Fiscal Year: 2006

Collaborators

Detail Information

Publications10

  1. ncbi Effects of age on axon terminals forming axosomatic and axodendritic inhibitory synapses in prefrontal cortex
    J J Soghomonian
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Neuroscience 168:74-81. 2010
    ..Furthermore, based on our and previously published results, we speculate that these changes are linked to age-related cognitive decline...
  2. ncbi L-DOPA-induced dyskinesia in adult rats with a unilateral 6-OHDA lesion of dopamine neurons is paralleled by increased c-fos gene expression in the subthalamic nucleus
    Jean Jacques Soghomonian
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Eur J Neurosci 23:2395-403. 2006
    ..These results suggest that altered cell signaling in the STN is involved in some of the behavioral effects induced by systemic L-DOPA administration...
  3. ncbi Dual effects of intermittent or continuous L-DOPA administration on gene expression in the globus pallidus and subthalamic nucleus of adult rats with a unilateral 6-OHDA lesion
    Kirsten M Nielsen
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Synapse 49:246-60. 2003
    ....
  4. ncbi Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications
    Jane Yip
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany St, R1003, Boston, MA 02118, USA
    Acta Neuropathol 113:559-68. 2007
    ..These findings may also contribute to the understanding of previous reports of alterations in the GABAergic system in limbic and cerebro-cortical areas contributing to a more widespread pathophysiology in autistic brains...
  5. ncbi Increased GAD67 mRNA expression in cerebellar interneurons in autism: implications for Purkinje cell dysfunction
    Jane Yip
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci Res 86:525-30. 2008
    ....
  6. ncbi Decreased glutamic acid decarboxylase mRNA expression in prefrontal cortex in Parkinson's disease
    Amélie C Lanoue
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts, 02118, USA
    Exp Neurol 226:207-17. 2010
    ..Altogether, the results support the possibility that GABAergic neurotransmission is impaired in the DLPFC in PD, an effect that may be involved in some of the behavioral deficits associated with the disease...
  7. ncbi Subchronic administration of L-DOPA to adult rats with a unilateral 6-hydroxydopamine lesion of dopamine neurons results in a sensitization of enhanced GABA release in the substantia nigra, pars reticulata
    Noriko Yamamoto
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Room L1001, Boston, MA 02118, USA
    Brain Res 1123:196-200. 2006
    ..These results show that the subchronic administration of L-DOPA results in a sensitization of enhanced extracellular GABA levels in the SNr...
  8. ncbi Haloperidol treatment after high-dose methamphetamine administration is excitotoxic to GABA cells in the substantia nigra pars reticulata
    Theo Hatzipetros
    Laboratory of Neurochemistry, Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci 27:5895-902. 2007
    ....
  9. ncbi High-dose methamphetamine acutely activates the striatonigral pathway to increase striatal glutamate and mediate long-term dopamine toxicity
    Karla A Mark
    Laboratory of Neurochemistry, Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci 24:11449-56. 2004
    ....
  10. ncbi Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study
    Jane Yip
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Autism Res 2:50-9. 2009
    ....

Research Grants5

  1. Behavioral Sensitization and Parkinson's Disease
    Jean Jacques Soghomonian; Fiscal Year: 2006
    ....