Affiliation: Boston University
- Impact of cigarette smoke on the normal airway transcriptomeAvrum Spira
Pulmonary Center, Boston University School of Medicine, Boston, University, Boston, MA 02118 2526, USA
Chest 125:115S. 2004
- SIEGE: Smoking Induced Epithelial Gene Expression DatabaseVishal Shah
Bioinformatics Program, College of Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Nucleic Acids Res 33:D573-9. 2005..Query results are embedded with graphical capabilities as well as with links to other databases containing valuable gene resources, including Entrez Gene, GO, Biocarta, GeneCards, dbSNP and the NCBI Map Viewer...
- Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancerAvrum Spira
The Pulmonary Center, Boston University Medical Center, 715 Albany Street, Boston, Massachusetts 02118, USA
Nat Med 13:361-6. 2007..These findings indicate that gene expression in cytologically normal large-airway epithelial cells can serve as a lung cancer biomarker, potentially owing to a cancer-specific airway-wide response to cigarette smoke...
- Gene expression profiling of human lung tissue from smokers with severe emphysemaAvrum Spira
The Pulmonary Center and Department of Medicine, Boston University School of Medicine, 715 Albany Street, R304, Boston, MA 02118, USA
Am J Respir Cell Mol Biol 31:601-10. 2004....
- Effects of cigarette smoke on the human airway epithelial cell transcriptomeAvrum Spira
Pulmonary Center and Department of Medicine, Boston University School of Medicine, 715 Albany Street, MA 02118, USA
Proc Natl Acad Sci U S A 101:10143-8. 2004....
- Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epitheliumSriram Sridhar
Pulmonary Center, Boston University School of Medicine, Albany Street, Boston Massachusetts, USA
BMC Genomics 9:259. 2008..In this study, we explored relationships in whole-genome gene expression between extrathorcic (buccal and nasal) and intrathoracic (bronchial) epithelium in healthy current and never smokers...
- Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokersKatrina Steiling
The Pulmonary Center, Boston University Medical Center, Boston, Massachusetts, United States of America
PLoS ONE 4:e5043. 2009....
- Apoptosis genes in human alveolar macrophages infected with virulent or attenuated Mycobacterium tuberculosis: a pivotal role for tumor necrosis factorAvrum Spira
St James s Hospital, James s St, Dublin 3, Ireland
Am J Respir Cell Mol Biol 29:545-51. 2003..Given the importance of TNF in host defense against tuberculosis, the ability to repress the expression of genes activated by TNF may constitute a bacillary virulence mechanism...
- Sophorolipids, microbial glycolipids with anti-human immunodeficiency virus and sperm-immobilizing activitiesVishal Shah
NSF Center for Biocatalysis and Bioprocessing of Macromolecules, Polytechnic University, Six Metrotech Center, Brooklyn, NY 11201, USA
Antimicrob Agents Chemother 49:4093-100. 2005..Its structure-activity relationship has been established for creating new analogs with less cytotoxicity and higher activity...