Carlo Serra

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Testosterone improves the regeneration of old and young mouse skeletal muscle
    Carlo Serra
    Section of Endocrinology, Diabetes, and Nutrition, Boston Medical Center, Boston, MA 02118, USA
    J Gerontol A Biol Sci Med Sci 68:17-26. 2013
  2. pmc The role of GH and IGF-I in mediating anabolic effects of testosterone on androgen-responsive muscle
    Carlo Serra
    Section of Endocrinology, Diabetes, and Nutrition, Boston Medical Center, 670 Albany Street, Boston, Massachusetts 02118, USA
    Endocrinology 152:193-206. 2011
  3. pmc Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells
    Wen Guo
    Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston Claude D Pepper Older Americans Independence Center, Boston Medical Center, Boston, MA 02118, USA
    Aging Cell 12:280-91. 2013
  4. pmc The Effects of a Single Developmentally Entrained Pulse of Testosterone in Female Neonatal Mice on Reproductive and Metabolic Functions in Adult Life
    Hyeran Jang
    Research Program in Men s Health Aging and Metabolism H J, S B, T G, C S, W G, K P, R J, Boston Claude D Pepper Older Americans Independence Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115 and Boston Nutrition and Obesity Research Center M S, M J L, S K F, Section of Endocrinology, Diabetes and Nutrition, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118
    Endocrinology 156:3737-46. 2015
  5. pmc Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy
    Ravi Jasuja
    Research Program in Men s Health Aging and Metabolism, Boston Claude D Pepper Older Americans Independence Center for Function, Promoting Anabolic Therapies, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA
    Aging Cell 13:303-10. 2014
  6. pmc Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking β-catenin nuclear translocation and cross-talk with TGF-β signaling in keratinocytes
    Gianluca Toraldo
    Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Wound Repair Regen 20:61-73. 2012
  7. pmc The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques
    Karyn E O'Connell
    Department of Comparative Pathology, New England Primate Research Center, Southborough, Massachusetts, USA and Research Program in Men s Health Aging and Metabolism, Boston Claude D Pepper Older Americans Independence Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    FASEB J 29:1165-75. 2015

Collaborators

Detail Information

Publications7

  1. pmc Testosterone improves the regeneration of old and young mouse skeletal muscle
    Carlo Serra
    Section of Endocrinology, Diabetes, and Nutrition, Boston Medical Center, Boston, MA 02118, USA
    J Gerontol A Biol Sci Med Sci 68:17-26. 2013
    ..These data suggest prospective application of androgens to improve the regenerating potential of the aged human skeletal muscle...
  2. pmc The role of GH and IGF-I in mediating anabolic effects of testosterone on androgen-responsive muscle
    Carlo Serra
    Section of Endocrinology, Diabetes, and Nutrition, Boston Medical Center, 670 Albany Street, Boston, Massachusetts 02118, USA
    Endocrinology 152:193-206. 2011
    ..However, IGF-IR signaling in skeletal muscle fibers does not appear to be obligatory for mediating the anabolic effects of T on the mass of androgen-responsive skeletal muscles in mice...
  3. pmc Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells
    Wen Guo
    Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston Claude D Pepper Older Americans Independence Center, Boston Medical Center, Boston, MA 02118, USA
    Aging Cell 12:280-91. 2013
    ..In conclusion, testosterone inhibits hepcidin transcription through its interaction with BMP/Smad signaling. Testosterone administration is associated with increased iron incorporation into red blood cells...
  4. pmc The Effects of a Single Developmentally Entrained Pulse of Testosterone in Female Neonatal Mice on Reproductive and Metabolic Functions in Adult Life
    Hyeran Jang
    Research Program in Men s Health Aging and Metabolism H J, S B, T G, C S, W G, K P, R J, Boston Claude D Pepper Older Americans Independence Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115 and Boston Nutrition and Obesity Research Center M S, M J L, S K F, Section of Endocrinology, Diabetes and Nutrition, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118
    Endocrinology 156:3737-46. 2015
    ..Collectively, these data suggest that sustained reproductive and metabolic alterations may result in female mice from a transient exposure to T during a narrow postnatal developmental window. ..
  5. pmc Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy
    Ravi Jasuja
    Research Program in Men s Health Aging and Metabolism, Boston Claude D Pepper Older Americans Independence Center for Function, Promoting Anabolic Therapies, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA
    Aging Cell 13:303-10. 2014
    ..Co-administration of testosterone and Odc1 inhibitor presents a novel therapeutic strategy for prostate-sparing anabolic therapy. ..
  6. pmc Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking β-catenin nuclear translocation and cross-talk with TGF-β signaling in keratinocytes
    Gianluca Toraldo
    Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Wound Repair Regen 20:61-73. 2012
    ..Together, these data show that blockade of β-catenin can, as a potential target for novel therapeutic interventions, accelerate cutaneous wound healing...
  7. pmc The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques
    Karyn E O'Connell
    Department of Comparative Pathology, New England Primate Research Center, Southborough, Massachusetts, USA and Research Program in Men s Health Aging and Metabolism, Boston Claude D Pepper Older Americans Independence Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    FASEB J 29:1165-75. 2015
    ..Administration of ActRIIB.Fc was associated with higher muscle expression of myostatin than placebo. ActRIIB.Fc effectively blocked and reversed loss of body weight, lean mass, and fat mass in juvenile SIV-infected rhesus macaques...