Research Topics
| Roberto ReifSummaryAffiliation: Boston University Country: USA Publications
Research Grants
| Collaborators |
Detail Information
Publications
Optical method for real-time monitoring of drug concentrations facilitates the development of novel methods for drug delivery to brain tissueRoberto Reif
Boston University, Department of Biomedical Engineering, 44 Cummington Street, Boston, Massachusetts 02215, USA
J Biomed Opt 12:034036. 2007..It is preliminarily determined in an animal model that the brain tissue uptake of chemotherapy agents-in this demonstration, MTX-delivered intra-arterially is enhanced when the BBB is disrupted...
Analytical model of light reflectance for extraction of the optical properties in small volumes of turbid mediaRoberto Reif
Department of Biomedical Engineering, Boston University, 44 Cummington Street, 4th Floor, Boston, Massachusetts 02215, USA
Appl Opt 46:7317-28. 2007..Accurate extraction of tissue optical properties from in vivo spectral measurements could have potential applications in detecting, noninvasively and in real time, epithelial (pre)cancers...
Analysis of changes in reflectance measurements on biological tissues subjected to different probe pressuresRoberto Reif
Boston University, Department of Biomedical Engineering, 44 Cummington Street, Boston, Massachusetts 02215, USA
J Biomed Opt 13:010502. 2008..The reflectance spectra are analyzed with an analytical model that extracts the tissue optical properties and facilitates the understanding of underlying physiological changes induced by the probe pressure...
Research Grants
- MINORITY PREDOCTORAL FELLOWSHIP PROGRAMRoberto Reif; Fiscal Year: 2007..It is difficult to predict the light dose required for a PDT effect at each point in the target tissue. Another application for the OP system will include detecting changes in capillary permeability caused by anti-angiogenic therapy. ..
