A Peters

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint The effects of aging on layer 1 in area 46 of prefrontal cortex in the rhesus monkey
    A Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
    Cereb Cortex 8:671-84. 1998
  2. doi request reprint The neuroglial population in the primary visual cortex of the aging rhesus monkey
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Glia 56:1151-61. 2008
  3. pmc Golgi, Cajal, and the fine structure of the nervous system
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Brain Res Rev 55:256-63. 2007
  4. ncbi request reprint A fourth type of neuroglial cell in the adult central nervous system
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    J Neurocytol 33:345-57. 2004
  5. ncbi request reprint Oligodendrocytes, their progenitors and other neuroglial cells in the aging primate cerebral cortex
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Cereb Cortex 14:995-1007. 2004
  6. ncbi request reprint The effects of normal aging on myelin and nerve fibers: a review
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715, Albany Street, Boston, MA 02118, USA
    J Neurocytol 31:581-93. 2002
  7. ncbi request reprint Examining neocortical circuits: some background and facts
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118 2526, USA
    J Neurocytol 31:183-93. 2002
  8. ncbi request reprint In aging, is it gray or white?
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 462:139-43. 2003
  9. ncbi request reprint Is there remyelination during aging of the primate central nervous system?
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 460:238-54. 2003
  10. ncbi request reprint Structural changes that occur during normal aging of primate cerebral hemispheres
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118 2526, USA
    Neurosci Biobehav Rev 26:733-41. 2002

Collaborators

Detail Information

Publications31

  1. ncbi request reprint The effects of aging on layer 1 in area 46 of prefrontal cortex in the rhesus monkey
    A Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
    Cereb Cortex 8:671-84. 1998
    ..Thus, the changes that occur with age in layer 1 provide one possible basis for the age-related cognitive impairment evidenced in monkeys and humans alike...
  2. doi request reprint The neuroglial population in the primary visual cortex of the aging rhesus monkey
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Glia 56:1151-61. 2008
    ....
  3. pmc Golgi, Cajal, and the fine structure of the nervous system
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Brain Res Rev 55:256-63. 2007
    ..However, Golgi/EM had only a brief, but fruitful existence. It was soon superceded by intracellular filling techniques, which allowed the added dimension that the physiological properties of identified neurons could also be determined...
  4. ncbi request reprint A fourth type of neuroglial cell in the adult central nervous system
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    J Neurocytol 33:345-57. 2004
    ....
  5. ncbi request reprint Oligodendrocytes, their progenitors and other neuroglial cells in the aging primate cerebral cortex
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Cereb Cortex 14:995-1007. 2004
    ....
  6. ncbi request reprint The effects of normal aging on myelin and nerve fibers: a review
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715, Albany Street, Boston, MA 02118, USA
    J Neurocytol 31:581-93. 2002
    ..Degeneration of myelin itself does not seem to result in microglial cells undertaking phagocytosis. These cells are probably only activated when large numbers of nerve fibers are lost, as can occur in the optic nerve...
  7. ncbi request reprint Examining neocortical circuits: some background and facts
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118 2526, USA
    J Neurocytol 31:183-93. 2002
    ....
  8. ncbi request reprint In aging, is it gray or white?
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 462:139-43. 2003
  9. ncbi request reprint Is there remyelination during aging of the primate central nervous system?
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 460:238-54. 2003
    ..Consequently, it is proposed that in the aging cerebral cortex of the monkey there is some breakdown of internodes of myelin with subsequent remyelination that leads to the formation of some new and shorter internodal lengths of myelin...
  10. ncbi request reprint Structural changes that occur during normal aging of primate cerebral hemispheres
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118 2526, USA
    Neurosci Biobehav Rev 26:733-41. 2002
    ..Microglial cells and astrocytes accumulate large amounts of phagocytosed material with age, although the origins of this material are not known...
  11. pmc How the primate fornix is affected by age
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 518:3962-80. 2010
    ....
  12. ncbi request reprint The effects of age on the cells in layer 1 of primate cerebral cortex
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Cereb Cortex 12:27-36. 2002
    ..These may be the sources of the material phagocytosed by the astrocytes and microglial cells...
  13. ncbi request reprint Aging and the myelinated fibers in prefrontal cortex and corpus callosum of the monkey
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    J Comp Neurol 442:277-91. 2002
    ....
  14. ncbi request reprint Structural changes in the normally aging cerebral cortex of primates
    Alan Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118 2526, USA
    Prog Brain Res 136:455-65. 2002
    ..It is suggested that the myelin changes alter conduction velocities along axons. This would alter timing in neuronal circuits, contributing to cognitive decline...
  15. pmc Age changes in myelinated nerve fibers of the cingulate bundle and corpus callosum in the rhesus monkey
    Michael P Bowley
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 518:3046-64. 2010
    ..These results further demonstrate the important role myelinated nerve fiber degeneration plays in the pathogenesis of age-related cognitive decline...
  16. ncbi request reprint The effects of aging on layer 1 of primary visual cortex in the rhesus monkey
    A Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Cereb Cortex 11:93-103. 2001
    ..These differences between layer 1 in these two cortical areas presumably relate to the fact that prefrontal cortex has a greater role in subserving cognition than does primary visual cortex...
  17. pmc Effects of age on axon terminals forming axosomatic and axodendritic inhibitory synapses in prefrontal cortex
    J J Soghomonian
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Neuroscience 168:74-81. 2010
    ..Furthermore, based on our and previously published results, we speculate that these changes are linked to age-related cognitive decline...
  18. pmc Synapses are lost during aging in the primate prefrontal cortex
    A Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118 2526, USA
    Neuroscience 152:970-81. 2008
    ..The synapse loss is also considered in light of earlier studies, which show that the frequency of spontaneous excitatory synaptic responses is reduced with age in layers 2/3 neurons...
  19. ncbi request reprint Effects of age on nerve fibers in the rhesus monkey optic nerve
    J H Sandell
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 429:541-53. 2001
    ..The degenerative changes were most marked in those optic nerves that contained the fewest nerve fibers...
  20. ncbi request reprint Effects of age on the thickness of myelin sheaths in monkey primary visual cortex
    A Peters
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA. apeters@ cajal-1.bu.edu
    J Comp Neurol 435:241-8. 2001
    ..Consequently, it seems that, with age, there is some degeneration of myelin but, at the same time, a continued production of lamellae...
  21. pmc Effects of normal aging on prefrontal area 46 in the rhesus monkey
    Jennifer Luebke
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA
    Brain Res Rev 62:212-32. 2010
    ..These factors contribute to alterations in the intrinsic and network physiological properties of cortical neurons. As more details emerge, it is to be hoped that effective interventions to retard cognitive decline can be proposed...
  22. ncbi request reprint An ultrastructural characterization of the newly generated cells in the adult monkey dentate gyrus
    Laura B Ngwenya
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Hippocampus 18:210-20. 2008
    ..The results demonstrate that immature neurons, immature astrocytes, and oligodendrocyte progenitor cells can be reliably distinguished by ultrastructural features, without immunohistochemical processing...
  23. ncbi request reprint Mitochondrial degeneration in dystrophic neurites of senile plaques may lead to extracellular deposition of fine filaments
    John C Fiala
    Department of Health Sciences, Boston University, 635 Commonwealth Ave, Boston, MA 02215, USA
    Brain Struct Funct 212:195-207. 2007
    ..This progression of degeneration suggests that extracellular filaments originate inside degenerating mitochondria of neuritic diverticula, which may be a common process in diverse diseases...
  24. ncbi request reprint Disrupted myelin and axon loss in the anterior commissure of the aged rhesus monkey
    Julie H Sandell
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 466:14-30. 2003
    ....
  25. ncbi request reprint Age-related molecular reorganization at the node of Ranvier
    Jason D Hinman
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 495:351-62. 2006
    ..Thus, age-dependent myelin alterations affect axonal protein localization and may be detrimental to maintenance of axonal conduction...
  26. ncbi request reprint Light and electron microscopic immunohistochemical detection of bromodeoxyuridine-labeled cells in the brain: different fixation and processing protocols
    Laura B Ngwenya
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany St, Boston, MA 02118, USA
    J Histochem Cytochem 53:821-32. 2005
    ..Additionally, we developed a protocol to visualize BrdU-labeled cells in the electron microscope with adequate preservation of fine structure in both rat and monkey brain...
  27. ncbi request reprint Effects of age on the glial cells in the rhesus monkey optic nerve
    Julie H Sandell
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    J Comp Neurol 445:13-28. 2002
    ..Some of the debris can be recognized as degenerating myelin, and in general, the greater the loss of nerve fibers, the more active the microglial cells become...
  28. ncbi request reprint Maturational sequence of newly generated neurons in the dentate gyrus of the young adult rhesus monkey
    Laura B Ngwenya
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Comp Neurol 498:204-16. 2006
    ....
  29. ncbi request reprint Long-term effects of cage-cleaning frequency and bedding type on laboratory rat health, welfare, and handleability: a cross-laboratory study
    Charlotte C Burn
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Lab Anim 40:353-70. 2006
    ..Nevertheless, cage-cleaning rates seem to affect socially housed male rats little, while bedding type has important effects on rat health...
  30. ncbi request reprint Sanford Louis Palay (23 September 1918 - 5 August 2002)
    Alan Peters
    Boston University
    Proc Am Philos Soc 148:519-28. 2004
  31. ncbi request reprint Guidance on the transport of laboratory animals
    Jeremy Swallow
    Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK
    Lab Anim 39:1-39. 2005