Joanne Murabito

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation
    Andrea D Coviello
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
    PLoS Genet 8:e1002805. 2012
  2. pmc Depressive symptoms are associated with visceral adiposity in a community-based sample of middle-aged women and men
    Joanne M Murabito
    Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    Obesity (Silver Spring) 21:1713-9. 2013
  3. pmc Reproductive aging-associated common genetic variants and the risk of breast cancer
    Chunyan He
    Department of Public Health, Indiana University School of Medicine, 980 West Walnut Street, R3 C241, Indianapolis, IN 46202, USA
    Breast Cancer Res 14:R54. 2012
  4. pmc The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals
    Joanne M Murabito
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA 01702, USA
    J Gerontol A Biol Sci Med Sci 67:470-9. 2012
  5. pmc Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies
    Joanne M Murabito
    Framingham Heart Study, 73 Mount Wayte Avenue, Framingham, MA 01701, USA
    Circ Cardiovasc Genet 5:100-12. 2012
  6. pmc Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study
    Christopher J O'Donnell
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S4. 2007
  7. pmc The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports
    L Adrienne Cupples
    National Heart Lung and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S1. 2007
  8. pmc Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes
    Martin G Larson
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S5. 2007
  9. pmc Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study
    Kathryn L Lunetta
    The National Heart Lung and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S13. 2007
  10. pmc Genome-wide association with bone mass and geometry in the Framingham Heart Study
    Douglas P Kiel
    Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, MA, USA
    BMC Med Genet 8:S14. 2007

Research Grants

Detail Information

Publications57

  1. pmc A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation
    Andrea D Coviello
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
    PLoS Genet 8:e1002805. 2012
    ..The evidence for sex-differentiated effects and allelic heterogeneity highlight the importance of considering these features when estimating complex trait variance...
  2. pmc Depressive symptoms are associated with visceral adiposity in a community-based sample of middle-aged women and men
    Joanne M Murabito
    Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    Obesity (Silver Spring) 21:1713-9. 2013
    ..2 years) and 1,718 men (mean age 49.8 years) in the Framingham Heart Study...
  3. pmc Reproductive aging-associated common genetic variants and the risk of breast cancer
    Chunyan He
    Department of Public Health, Indiana University School of Medicine, 980 West Walnut Street, R3 C241, Indianapolis, IN 46202, USA
    Breast Cancer Res 14:R54. 2012
    ..Recent genome-wide association studies have identified several novel genetic loci associated with these two traits. However, the association between these loci and breast cancer risk is unknown...
  4. pmc The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals
    Joanne M Murabito
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA 01702, USA
    J Gerontol A Biol Sci Med Sci 67:470-9. 2012
    ..We expect these ongoing collaborations and the translational work with basic scientists to accelerate the identification of genes that delay aging and promote a healthy life span...
  5. pmc Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies
    Joanne M Murabito
    Framingham Heart Study, 73 Mount Wayte Avenue, Framingham, MA 01701, USA
    Circ Cardiovasc Genet 5:100-12. 2012
    ..To identify genetic variants associated with the ankle-brachial index (ABI), a noninvasive measure of PAD, we conducted a meta-analysis of genome-wide association study data from 21 population-based cohorts...
  6. pmc Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study
    Christopher J O'Donnell
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S4. 2007
    ..We conducted a genome-wide association study (GWAS) for SCA measurements in the community-based Framingham Heart Study...
  7. pmc The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports
    L Adrienne Cupples
    National Heart Lung and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S1. 2007
    ....
  8. pmc Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes
    Martin G Larson
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S5. 2007
    ..Prior investigations have reported several single gene variants associated with CHD, stroke, HF, and AF. We report a community-based genome-wide association study of major CVD outcomes...
  9. pmc Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study
    Kathryn L Lunetta
    The National Heart Lung and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S13. 2007
    ..Family studies and heritability estimates provide evidence for a genetic contribution to variation in the human life span...
  10. pmc Genome-wide association with bone mass and geometry in the Framingham Heart Study
    Douglas P Kiel
    Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, MA, USA
    BMC Med Genet 8:S14. 2007
    ..There have been no genome-wide association and linkage studies for these traits using high-density genotyping platforms...
  11. ncbi request reprint Sibling cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults
    Joanne M Murabito
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Mass 01702, USA
    JAMA 294:3117-23. 2005
    ..While parental cardiovascular disease (CVD) doubles the risk for CVD in offspring, the extent of increased risk associated with sibling CVD is unclear...
  12. ncbi request reprint Heritability of the ankle-brachial index: the Framingham Offspring study
    Joanne M Murabito
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA 01702, USA
    Am J Epidemiol 164:963-8. 2006
    ..27 (standard error, 0.06), 0.30 (standard error, 0.06), and 0.21 (standard error, 0.06), respectively (all p values < 0.0001). A modest proportion of the variability in ABI is explained by genetic factors...
  13. pmc Cross-sectional relations of multiple inflammatory biomarkers to peripheral arterial disease: The Framingham Offspring Study
    Joanne M Murabito
    National Heart, Lung and Blood Institute s Framingham Heart Study, Framingham, MA 01702 5827, United States
    Atherosclerosis 203:509-14. 2009
    ..Emerging evidence suggests that different inflammatory biomarkers operate through distinct biologic mechanisms. We hypothesized that the relation to peripheral arterial disease (PAD) varies for individual markers...
  14. pmc Temporal trends in self-reported functional limitations and physical disability among the community-dwelling elderly population: the Framingham heart study
    Joanne M Murabito
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    Am J Public Health 98:1256-62. 2008
    ..We sought to determine change in the prevalence of functional limitations and physical disability among the community-dwelling elderly population across 3 decades...
  15. pmc A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study
    Joanne M Murabito
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S6. 2007
    ..Breast and prostate cancer are two commonly diagnosed cancers in the United States. Prior work suggests that cancer causing genes and cancer susceptibility genes can be identified...
  16. ncbi request reprint Genome-wide linkage analysis to age at natural menopause in a community-based sample: the Framingham Heart Study
    Joanne M Murabito
    National Heart Lung and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    Fertil Steril 84:1674-9. 2005
    ..To identify chromosomal regions linked to age at natural menopause...
  17. ncbi request reprint Heritability of age at natural menopause in the Framingham Heart Study
    Joanne M Murabito
    National Heart, Lung, and Blood Institute s Framingham Heart Study, 73 Mount Wayte Avenue, Suite 2, Framingham, Massachusetts 01702 5827, USA
    J Clin Endocrinol Metab 90:3427-30. 2005
    ..We sought to estimate heritability of age at natural menopause in women participating in the multigenerational Framingham Heart Study, a community-based epidemiological study...
  18. ncbi request reprint Temporal trends in the incidence of intermittent claudication from 1950 to 1999
    Joanne M Murabito
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA 01702 5827, USA
    Am J Epidemiol 162:430-7. 2005
    ..IC incidence has declined since 1950, but mortality has remained high and unchanged. Factors contributing to the declining incidence of IC need clarification...
  19. pmc Intramuscular fat and associations with metabolic risk factors in the Framingham Heart Study
    Kate E Therkelsen
    Boston University School of Medicine, Boston, MA, USA
    Arterioscler Thromb Vasc Biol 33:863-70. 2013
    ..Intramuscular fat accumulates between muscle fibers or within muscle cells. We investigated the association of intramuscular fat with other ectopic fat deposits and metabolic risk factors...
  20. pmc Genetics of the Framingham Heart Study population
    Diddahally R Govindaraju
    Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Adv Genet 62:33-65. 2008
    ..Finally, the use of this unique sample to study genotype and environment interactions is described...
  21. ncbi request reprint Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study
    Thomas J Wang
    Framingham Heart Study, 73 Mt Wayte Ave, Suite 2, Framingham, Mass 01702 5827, USA
    Circulation 107:2920-5. 2003
    ..Atrial fibrillation (AF) and congestive heart failure (CHF) frequently occur together, but there is limited information regarding their temporal relations and the combined influence of these conditions on mortality...
  22. ncbi request reprint Prevalence and clinical correlates of peripheral arterial disease in the Framingham Offspring Study
    Joanne M Murabito
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Mass 01702 5827, USA
    Am Heart J 143:961-5. 2002
    ..Peripheral arterial disease (PAD) is associated with an increased risk for mortality. We sought to assess the prevalence of PAD and its risk factors in a population-based sample...
  23. pmc Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study
    Nisha I Parikh
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA 01702 5803, USA
    Circulation 119:1203-10. 2009
    ..We hypothesized that this paradox is due partly to the advent of increasingly sensitive biomarkers for AMI diagnosis...
  24. ncbi request reprint Lifetime risk for developing congestive heart failure: the Framingham Heart Study
    Donald M Lloyd-Jones
    National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Framingham, MA 01702, USA
    Circulation 106:3068-72. 2002
    ..Congestive heart failure (CHF) is an increasing public health problem...
  25. ncbi request reprint The ankle-brachial index in the elderly and risk of stroke, coronary disease, and death: the Framingham Study
    Joanne M Murabito
    National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Framingham, MA 01702 5827, USA
    Arch Intern Med 163:1939-42. 2003
    ..Limited data exist regarding the relation between a low ABI and stroke. We sought to examine the relation between a low ABI and stroke, coronary heart disease, and death in the elderly...
  26. pmc The spread of alcohol consumption behavior in a large social network
    J Niels Rosenquist
    Massachusetts General Hospital, Harvard Medical School, and Boston University School of Medicine, 180 A Longwood Avenue, Boston, MA 02115, USA
    Ann Intern Med 152:426-33, W141. 2010
    ..Alcohol consumption has important health-related consequences and numerous biological and social determinants...
  27. ncbi request reprint Characteristics of Framingham offspring participants with long-lived parents
    Dellara F Terry
    Boston University School of Medicine, Geriatrics Section, Boston Medical Center, 88 E Newton St, Robinson 2, Boston, MA 02118, USA
    Arch Intern Med 167:438-44. 2007
    ..Prior research has suggested that delay or avoidance of cardiovascular disease and cardiovascular disease risk factors plays an important role in longevity...
  28. ncbi request reprint Long-term trends in the incidence of and survival with heart failure
    Daniel Levy
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Mass, USA
    N Engl J Med 347:1397-402. 2002
    ..Heart failure is a major public health problem. Long-term trends in the incidence of heart failure and survival after its onset in the community have not been characterized...
  29. ncbi request reprint Accuracy of offspring reports of parental cardiovascular disease history: the Framingham Offspring Study
    Joanne M Murabito
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    Ann Intern Med 140:434-40. 2004
    ..Family history is used to infer the risk for heart disease; however, little is known about the accuracy of family history reports...
  30. pmc Long-term trends in the incidence of heart failure after myocardial infarction
    Raghava S Velagaleti
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA 01702 5803, USA
    Circulation 118:2057-62. 2008
    ....
  31. ncbi request reprint Parental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation cohorts
    Nisha I Parikh
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Mass, USA
    Circulation 116:1473-81. 2007
    ..We related validated parental premature CVD with the subclinical measures of coronary artery (CAC) and abdominal aortic (AAC) calcification in the community...
  32. ncbi request reprint Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study
    Caroline S Fox
    National Heart, Lung and Blood Institute s Framingham Heart Study, Framingham, Mass, USA
    Circulation 116:39-48. 2007
    ..The incremental utility of measuring both visceral and subcutaneous abdominal adipose tissue (SAT) in association with metabolic risk factors and underlying heritability has not been well described in a population-based setting...
  33. ncbi request reprint The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination
    Greta Lee Splansky
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Boston University School of Medicine, Framingham, MA 01702 5827, USA
    Am J Epidemiol 165:1328-35. 2007
    ....
  34. ncbi request reprint Prevalence and prognostic impact of subclinical cardiovascular disease in individuals with the metabolic syndrome and diabetes
    Erik Ingelsson
    National Heart, Lung, and Blood Institute s Framingham Study, Framingham, Massachusetts 01702 5803, USA
    Diabetes 56:1718-26. 2007
    ..93 [1.15-3.24]). In our community-based sample, individuals with MetS have a high prevalence of subclinical atherosclerosis that likely contributes to the increased risk of overt CVD associated with the condition...
  35. ncbi request reprint Cardiovascular risk factors predictive for survival and morbidity-free survival in the oldest-old Framingham Heart Study participants
    Dellara F Terry
    Department of Geriatrics, Boston Medical Center, School of Medicine, Boston University, Boston, Massachusetts 02118, USA
    J Am Geriatr Soc 53:1944-50. 2005
    ..To examine whether midlife cardiovascular risk factors predict survival and survival free of major comorbidities to the age of 85...
  36. pmc Periaortic fat deposition is associated with peripheral arterial disease: the Framingham heart study
    Caroline S Fox
    National Heart, Lung, and Blood Institute Framingham Heart Study, Bethesda, MD, USA
    Circ Cardiovasc Imaging 3:515-9. 2010
    ..We hypothesized that persons with greater amounts of periaortic fat are more likely to have clinical PAD and a low ankle-brachial index...
  37. ncbi request reprint Prediction of intermittent claudication, ischemic stroke, and other cardiovascular disease by detection of abdominal aortic calcific deposits by plain lumbar radiographs
    Yamini S Levitzky
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Am J Cardiol 101:326-31. 2008
    ..AAC appears to be useful for risk stratification in patients at intermediate CHD risk...
  38. ncbi request reprint Relations of serum aldosterone to cardiac structure: gender-related differences in the Framingham Heart Study
    Ramachandran S Vasan
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Bethesda, MD, USA
    Hypertension 43:957-62. 2004
    ..Additional investigations are warranted to confirm these findings...
  39. ncbi request reprint Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study
    Yamini S Levitzky
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    J Am Coll Cardiol 51:264-70. 2008
    ..We sought to determine whether impaired fasting glucose (IFG) predicts cardiovascular disease (CVD) events...
  40. ncbi request reprint Genomewide linkage analysis of weight change in the Framingham Heart Study
    Caroline S Fox
    National Heart, Lung, and Blood Institute s Framingham Heart Study, 73 Mount Wayte Avenue, Suite 2, Framingham, Massachusetts 01702, USA
    J Clin Endocrinol Metab 90:3197-201. 2005
    ..Weight gain adversely affects blood pressure, lipids, and glycemia. The genetic contribution to weight change is unknown...
  41. pmc Breastfeeding in infancy and adult cardiovascular disease risk factors
    Nisha I Parikh
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Mass, USA
    Am J Med 122:656-63.e1. 2009
    ..Several prior studies relating breastfeeding to cardiovascular risk factors have been limited by lack of adjustment for maternal and participant confounding factors...
  42. ncbi request reprint Burden and prognostic importance of subclinical cardiovascular disease in overweight and obese individuals
    Erik Ingelsson
    Framingham Heart Study, 73 Mount Wayte Ave, Framingham, MA 01702 5803, USA
    Circulation 116:375-84. 2007
    ..The burden and prognostic importance of subclinical cardiovascular disease (CVD) in obesity has not been investigated systematically...
  43. ncbi request reprint Endogenous sex hormones and cardiovascular disease incidence in men
    Johan Arnlov
    National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Bethesda, Maryland, USA
    Ann Intern Med 145:176-84. 2006
    ..Yet, prospective studies relating sex hormones to CVD incidence in men have yielded inconsistent results...
  44. pmc Sex- and age-interacting eQTLs in human complex diseases
    Chen Yao
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    Hum Mol Genet 23:1947-56. 2014
    ..We show that these eQTLs are also associated with many sex- or age-associated traits. These findings provide important context regarding the regulation of phenotypes by genotype-environment interaction...
  45. doi request reprint Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample
    Caroline S Fox
    National Heart, Lung, and Blood Institute s Framingham Heart Study, 73 Mt Wayte Ave, Ste 2, Framingham, MA 01702, USA
    Arch Intern Med 168:587-92. 2008
    ..Overt hypothyroidism and hyperthyroidism may be associated with weight gain and loss. We assessed whether variations in thyroid function within the reference (physiologic) range are associated with body weight...
  46. ncbi request reprint Sex-specific association between estrogen receptor-alpha gene variation and measures of adiposity: the Framingham Heart Study
    Caroline S Fox
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702, USA
    J Clin Endocrinol Metab 90:6257-62. 2005
    ..Polymorphisms in estrogen receptor-alpha (ESR1) may be associated with variation in body mass index and waist circumference. However, most prior studies have been limited by sample size and power...
  47. pmc Health insurance and cardiovascular disease risk factors
    Erica L Brooks
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Mass 01702 5803, USA
    Am J Med 123:741-7. 2010
    ..Compared with those with health insurance, the uninsured receive less care for chronic conditions, such as hypertension and diabetes, and experience higher mortality...
  48. pmc Consent for genetic research in the Framingham Heart Study
    Daniel Levy
    Center for Population Studies, National Heart, Lung, and Blood Institute, Bethesda, MA 01702, USA
    Am J Med Genet A 152:1250-6. 2010
    ..Published 2010 Wiley-Liss, Inc...
  49. ncbi request reprint Clinical and genetic correlates of serum aldosterone in the community: the Framingham Heart Study
    Sekar Kathiresan
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    Am J Hypertens 18:657-65. 2005
    ..We investigated the environmental and genetic sources of interindividual variability in serum aldosterone level in a large, community-based sample...
  50. ncbi request reprint Effect of medical conditions on improvement in self-reported and observed functional performance of elders
    Ram R Miller
    Geriatrics Section, Boston University School of Medicine, Boston, Massachusetts, USA
    J Am Geriatr Soc 52:217-23. 2004
    ..To evaluate the effect of nine disabling medical conditions upon recovery from functional limitations by elders...
  51. ncbi request reprint Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: a prospective study of parents and offspring
    Donald M Lloyd-Jones
    Department of Preventive Medicine and Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    JAMA 291:2204-11. 2004
    ..Whether parental cardiovascular disease confers increased risk independent of other risk factors remains controversial. Prior studies relied on offspring report, without complete validation of parental events...
  52. ncbi request reprint Smoking, alcohol consumption, and Raynaud's phenomenon in middle age
    Lisa G Suter
    VA Connecticut Healthcare System, West Haven, Conn, USA
    Am J Med 120:264-71. 2007
    ..Our objective was to determine whether smoking and alcohol are independently associated with Raynaud's in a large, community-based cohort...
  53. ncbi request reprint The incidence and natural history of Raynaud's phenomenon in the community
    Lisa G Suter
    Yale University School of Medicine, New Haven, Connecticut 06520 8088, USA
    Arthritis Rheum 52:1259-63. 2005
    ..Our objective was to determine the incidence and natural history of RP not associated with a connective tissue disease in a large, community-based population...
  54. ncbi request reprint Depressive symptoms, coronary heart disease, and overall mortality in the Framingham Heart Study
    Lawson R Wulsin
    Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio, USA
    Psychosom Med 67:697-702. 2005
    ....
  55. pmc Advance care planning and health care preferences of community-dwelling elders: the Framingham Heart Study
    Ellen P McCarthy
    Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, 1309 Beacon Street, Suite 220, Brookline, MA 02446, USA
    J Gerontol A Biol Sci Med Sci 63:951-9. 2008
    ..The study objective was to describe self-reported advance care planning, health care preferences, use of advance directives, and health perceptions in a very elderly community-dwelling sample...
  56. pmc Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels
    Inga Peter
    Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA
    J Clin Endocrinol Metab 93:2779-85. 2008
    ..To explore potential mechanisms by which these gene variants may contribute to cardiovascular disease, we tested the hypothesis that the polymorphisms were associated with endogenous steroid hormone levels...
  57. ncbi request reprint Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study
    Karla M Pou
    Division of Endocrinology, Metabolism, and Diabetes, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass, USA
    Circulation 116:1234-41. 2007
    ..Excess adiposity is associated with greater systemic inflammation. Whether visceral adiposity is more proinflammatory than subcutaneous abdominal adiposity is unclear...

Research Grants4

  1. Genetics of Reproductive Life Period and Health Outcomes
    Joanne Murabito; Fiscal Year: 2008
    ..Knowledge gained may lead to innovative diagnostic and therapeutic interventions to improve the overall health of women and possibly of men. ..
  2. Exceptional Aging Across the Life Span: Framingham Study
    Joanne Murabito; Fiscal Year: 2009
    ..Knowledge gained from this proposal may lead to interventions that prevent age-related disease and disability so that older persons spend more time in good health. ..
  3. Exceptional Aging Across the Life Span: Framingham Study
    Joanne M Murabito; Fiscal Year: 2010
    ..Knowledge gained from this proposal may lead to interventions that prevent age-related disease and disability so that older persons spend more time in good health. ..
  4. Exceptional Aging Across the Life Span: Framingham Study
    Joanne Murabito; Fiscal Year: 2008
    ..Knowledge gained from this proposal may lead to interventions that prevent age-related disease and disability so that older persons spend more time in good health. ..