Research Topics
| Monty A MontanoSummaryAffiliation: Boston University Country: USA Publications
Research Grants
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Detail Information
Publications
BET bromodomain inhibition as a novel strategy for reactivation of HIV-1Camellia Banerjee
Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
J Leukoc Biol 92:1147-54. 2012..Thus, JQ1 may be useful in studies of potentially novel mechanisms for transcriptional control as well as in translational efforts to identify therapeutic molecules to achieve viral eradication...
Premature expression of a muscle fibrosis axis in chronic HIV infectionRebecca L Kusko
Boston University School of Medicine, 650 Albany St, EBRC 646, Boston, MA, 02118, USA
Skelet Muscle 2:10. 2012..abstract:..
A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samplesPaola Sebastiani
Department of Biostatistics, Boston University School of Public Health, Boston 02118 MA, USA
BMC Genet 9:6. 2008..One of the challenges of the analysis of pooling-based genome wide association studies is to identify authentic associations among potentially thousands of false positive associations...
Conditional clustering of temporal expression profilesLing Wang
Novartis Vaccines and Diagnostics, Emeryville, CA 94608, USA
BMC Bioinformatics 9:147. 2008..Many microarray experiments produce temporal profiles in different biological conditions but common cluster techniques are not able to analyze the data conditional on the biological conditions...
Gene-expression profiling of HIV-1 infection and perinatal transmission in BotswanaM Montano
Center for HIV 1 AIDS Care and Research, Boston University School of Medicine, MA 2446, USA
Genes Immun 7:298-309. 2006..HIV-1 pathogen-specific host profiles should prove a useful tool in infection and transmission intervention efforts worldwide...
Comparative prediction of perinatal human immunodeficiency virus type 1 transmission, using multiple virus load markersMonty Montano
Harvard School of Public Health, Boston, Massachusetts, USA
J Infect Dis 188:406-13. 2003..30; 95% CI, 2.11-50.38). When blood HIV-1 DNA load was combined with CVF HIV-1 DNA load, the association with transmission increased (OR, 25.0; 95% CI 2.73-228.60)...
MicroRNAs: miRRORS of health and diseaseMonty Montano
Department of Medicine, Boston University Medical Campus, Boston, MA 02118, USA
Transl Res 157:157-62. 2011....
RNA surveillance-an emerging role for RNA regulatory networks in agingMonty Montano
Department of Medicine, Boston University School of Medicine, MA, USA
Ageing Res Rev 10:216-24. 2011..We end with a discussion of RNA surveillance as a robust regulatory system that can change in response to environmental stressors and represents a novel axis in aging science...
Transcriptional profiling of testosterone-regulated genes in the skeletal muscle of human immunodeficiency virus-infected men experiencing weight lossMonty Montano
Section of Infectious Diseases, Center for HIV 1 AIDS Care and Research, School of Public Health, Boston University, Boston, Massachusetts 02118, USA
J Clin Endocrinol Metab 92:2793-802. 2007..Although androgen treatment increases muscle mass, the cell-intrinsic mechanisms engaged remain poorly understood...
HIV-1 burden influences host response to co-infection with Neisseria gonorrhoeae in vitroMonty Montano
Department of Medicine, Section of Infectious Diseases, Center for HIV-1/AIDS Care and Research, Boston University School of Medicine, USA
Int Immunol 18:125-37. 2006..Further evaluation of these findings may help to better understand the role of viral burden in defining cellular contribution to host immune response upon co-infection with secondary sexually transmitted pathogens...
RNA editing genes associated with extreme old age in humans and with lifespan in C. elegansPaola Sebastiani
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
PLoS ONE 4:e8210. 2009..The majority of genes found thus far to be associated with longevity primarily function in lipoprotein metabolism and insulin/IGF-1 signaling. There are likely many more genetic modifiers of human longevity that remain to be discovered...
Infant morbidity, mortality, and breast milk immunologic profiles among breast-feeding HIV-infected and HIV-uninfected women in BotswanaRoger L Shapiro
Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
J Infect Dis 196:562-9. 2007..Infants of human immunodeficiency virus (HIV)-infected women have high mortality, but the immunologic integrity and protection afforded by the breast milk of HIV-infected women is unknown...
The RNA editor gene ADAR1 is induced in myoblasts by inflammatory ligands and buffers stress responseMicah Meltzer
Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
Clin Transl Sci 3:73-80. 2010..Collectively, these data identify a novel regulatory role for ADAR1 activation under inflammatory stress to both promote muscle protein synthesis pathways and limit atrophy pathways...
Sca-1 influences the innate immune response during skeletal muscle regenerationKimberly K Long
Boston Medical Center, Department of Medicine, Section of Infectious Diseases, Boston, Massachusetts, USA
Am J Physiol Cell Physiol 300:C287-94. 2011..Collectively, these data reveal a novel role for Sca-1 in innate immunity during muscle regeneration and indicate that further elucidation of immuno-myogenic processes will help to better understand and promote muscle regeneration...
Evidence for cross-regulated cytokine response in human peripheral blood mononuclear cells exposed to whole gonococcal bacteria in vitroMatthew Rarick
Center for HIV-1/AIDS Care and Research, Section of Infectious Diseases, Boston University School of Medicine, 650 Albany Street, EBRC 640, Boston, MA 02118, USA
Microb Pathog 40:261-70. 2006....
Differential regulation of HIV-1 clade-specific B, C, and E long terminal repeats by NF-kappaB and the Tat transactivatorPhilippe Roof
McGill AIDS Center, McGill University, Montreal, Quebec, Canada
Virology 296:77-83. 2002..Furthermore, preliminary evidence suggests that the acetylation of subtype-specific Tat proteins may correlate with their transactivation efficiency...
Research Grants
- Molecular Analysis of HIV-1C Transmission CofactorsMonty Montano; Fiscal Year: 2005..abstract_text> ..
- Macrophage-Muscle Precursor Cell Interaction in the Context of HIV InfectionMonty Montano; Fiscal Year: 2007....
- Macrophage-Muscle Precursor Cell Interaction in the Context of HIV InfectionMonty A Montano; Fiscal Year: 2010....
