Paul A Monach

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc IgG4-related Disease: 2013 Update
    Paul A Monach
    Vasculitis Center and Section of Rheumatology, Boston University School of Medicine, 72 East Concord Street, E 533, Boston, MA, 02118, USA
    Curr Treat Options Cardiovasc Med 15:214-23. 2013
  2. pmc Repeating tests: different roles in research studies and clinical medicine
    Paul A Monach
    Department of Medicine, Section of Rheumatology, Boston University School of Medicine, 72 E Concord St, E 533, Boston, MA 02118, USA
    Biomark Med 6:691-703. 2012
  3. pmc Circulating angiopoietin-2 as a biomarker in ANCA-associated vasculitis
    Paul A Monach
    Section of Rheumatology, Department of Medicine, School of Medicine, Vasculitis Center, Boston University, Boston, Massachusetts, United States of America
    PLoS ONE 7:e30197. 2012
  4. pmc Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis
    Wolfgang Hueber
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University, Stanford, CA 94305, USA
    Arthritis Res Ther 11:R76. 2009
  5. doi request reprint Genetics of vasculitis
    Paul A Monach
    Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Curr Opin Rheumatol 22:157-63. 2010
  6. pmc Distribution of arterial lesions in Takayasu's arteritis and giant cell arteritis
    Peter C Grayson
    The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts, USA
    Ann Rheum Dis 71:1329-34. 2012
  7. pmc Circulating markers of vascular injury and angiogenesis in antineutrophil cytoplasmic antibody-associated vasculitis
    Paul A Monach
    Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Arthritis Rheum 63:3988-97. 2011
  8. pmc Assessment of health-related quality of life as an outcome measure in granulomatosis with polyangiitis (Wegener's)
    Gunnar Tomasson
    Boston University, Boston, Massachusetts, USA
    Arthritis Care Res (Hoboken) 64:273-9. 2012
  9. pmc Association of vascular physical examination findings and arteriographic lesions in large vessel vasculitis
    Peter C Grayson
    Vasculitis Center, Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Rheumatol 39:303-9. 2012
  10. doi request reprint Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis
    Paul A Monach
    Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, USA
    Ann Rheum Dis 72:1342-50. 2013

Detail Information

Publications17

  1. pmc IgG4-related Disease: 2013 Update
    Paul A Monach
    Vasculitis Center and Section of Rheumatology, Boston University School of Medicine, 72 East Concord Street, E 533, Boston, MA, 02118, USA
    Curr Treat Options Cardiovasc Med 15:214-23. 2013
    ..In the event or subsequent relapse, I would stop azathioprine and use rituximab. In a patient with large artery involvement, I would consult a vascular surgeon soon after diagnosis, anticipating a need for surgical repair...
  2. pmc Repeating tests: different roles in research studies and clinical medicine
    Paul A Monach
    Department of Medicine, Section of Rheumatology, Boston University School of Medicine, 72 E Concord St, E 533, Boston, MA 02118, USA
    Biomark Med 6:691-703. 2012
    ..e., ones that are critical for clinical decision-making)...
  3. pmc Circulating angiopoietin-2 as a biomarker in ANCA-associated vasculitis
    Paul A Monach
    Section of Rheumatology, Department of Medicine, School of Medicine, Vasculitis Center, Boston University, Boston, Massachusetts, United States of America
    PLoS ONE 7:e30197. 2012
    ..Thus, Ang-2 appears to have limited practical value in AAV as a biomarker of disease activity at time of measurement or for predicting future activity...
  4. pmc Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis
    Wolfgang Hueber
    Department of Medicine, Division of Immunology and Rheumatology, Stanford University, Stanford, CA 94305, USA
    Arthritis Res Ther 11:R76. 2009
    ..Since no clinical or laboratory tests are available to predict response to anti-TNF therapies, great need exists for predictive biomarkers...
  5. doi request reprint Genetics of vasculitis
    Paul A Monach
    Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Curr Opin Rheumatol 22:157-63. 2010
    ..Cohorts have been assembled that are of sufficient size to allow application of up-to-date methods of genetic analysis. This review will summarize the current understanding of the genetics of several forms of vasculitis...
  6. pmc Distribution of arterial lesions in Takayasu's arteritis and giant cell arteritis
    Peter C Grayson
    The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts, USA
    Ann Rheum Dis 71:1329-34. 2012
    ..To compare patterns of arteriographic lesions of the aorta and primary branches in patients with Takayasu's arteritis (TAK) and giant cell arteritis (GCA)...
  7. pmc Circulating markers of vascular injury and angiogenesis in antineutrophil cytoplasmic antibody-associated vasculitis
    Paul A Monach
    Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Arthritis Rheum 63:3988-97. 2011
    ..To identify biomarkers that distinguish between active antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and remission in a manner superior or complementary to established markers of systemic inflammation...
  8. pmc Assessment of health-related quality of life as an outcome measure in granulomatosis with polyangiitis (Wegener's)
    Gunnar Tomasson
    Boston University, Boston, Massachusetts, USA
    Arthritis Care Res (Hoboken) 64:273-9. 2012
    ..To assess a generic measure of health-related quality of life (HRQOL) as an outcome measure in granulomatosis with polyangiitis (Wegener's) (GPA)...
  9. pmc Association of vascular physical examination findings and arteriographic lesions in large vessel vasculitis
    Peter C Grayson
    Vasculitis Center, Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Rheumatol 39:303-9. 2012
    ..To assess the utility of the vascular physical examination to detect arteriographic lesions in patients with established large vessel vasculitis (LVV), including Takayasu's arteritis (TAK) and giant cell arteritis (GCA)...
  10. doi request reprint Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis
    Paul A Monach
    Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, USA
    Ann Rheum Dis 72:1342-50. 2013
    ..To identify circulating proteins that distinguish between active anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and remission in a manner complementary to markers of systemic inflammation...
  11. doi request reprint urinary biomarkers in relapsing antineutrophil cytoplasmic antibody-associated vasculitis
    Jason G Lieberthal
    Department of Medicine, Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA
    J Rheumatol 40:674-83. 2013
    ..We investigated 4 urinary proteins as markers of active renal AAV: alpha-1 acid glycoprotein (AGP), kidney injury molecule-1 (KIM-1), monocyte chemoattractant protein-1 (MCP-1), and neutrophil gelatinase-associated lipocalin (NGAL)...
  12. pmc IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis
    James M Kelley
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Proc Natl Acad Sci U S A 108:20736-41. 2011
    ..0001). FcR genotypes, IgA ANCA, and IgG ANCA are potential prognostic and therapeutic targets for understanding the pathogenesis and presentation of granulomatosis with polyangiitis (Wegener's)...
  13. pmc Thromboembolic disease in vasculitis
    Gunnar Tomasson
    The Vasculitis Center, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts 02118, USA
    Curr Opin Rheumatol 21:41-6. 2009
    ..To give an overview of recent clinical findings of thromboembolic disease in vasculitis and provide insight into possible explanations of the association between thrombosis and inflammation...
  14. pmc Rituximab versus cyclophosphamide for ANCA-associated vasculitis
    John H Stone
    Massachusetts General Hospital, Boston, USA
    N Engl J Med 363:221-32. 2010
    ..Uncontrolled studies suggest that rituximab is effective and may be safer than a cyclophosphamide-based regimen...
  15. pmc Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1
    Paul A Monach
    Joslin Diabetes Center, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    Arthritis Rheum 62:753-64. 2010
    ..In this study, we developed a system with which to test the importance of the production of specific factors by neutrophils in a mouse model of arthritis...
  16. pmc Antineutrophil cytoplasmic antibodies, autoimmune neutropenia, and vasculitis
    Peter C Grayson
    Vasculitis Center, Section of Rheumatology, Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA
    Semin Arthritis Rheum 41:424-33. 2011
    ..A case of ANCA-associated vasculitis (AAV) with recurrent neutropenia is described and relevant literature on the association between ANCA, neutropenia, and vasculitis is reviewed...
  17. pmc A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis
    Paul A Monach
    Section on Immunology and Immunogenetics, the Joslin Diabetes Center, Boston, Massachusetts, USA
    Proc Natl Acad Sci U S A 106:15867-72. 2009
    ..Thus, autoantibodies to many determinants (whether deposited as "neoantigens" or normal constituents of the extracellular matrix) have the potential to contribute to arthritic inflammation...