JEROME C MERTZ

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint Nonlinear microscopy: new techniques and applications
    Jerome Mertz
    Boston University, Department of Biomedical Engineering, 44 Cummington Street, Boston, Massachusetts 02215, USA
    Curr Opin Neurobiol 14:610-6. 2004
  2. pmc Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection
    Jerome Mertz
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts 02215, USA
    J Biomed Opt 15:016027. 2010
  3. doi request reprint Widefield fluorescence sectioning with HiLo microscopy
    Jerome Mertz
    Boston University, Department of Biomedical Engineering, 44 Cummington St, Boston, MA, 02215, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:3229-30. 2009
  4. doi request reprint Optical sectioning microscopy with planar or structured illumination
    Jerome Mertz
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA
    Nat Methods 8:811-9. 2011
  5. ncbi request reprint Wide-field fluorescence sectioning with hybrid speckle and uniform-illumination microscopy
    Daryl Lim
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Opt Lett 33:1819-21. 2008
  6. ncbi request reprint Fluorescence endomicroscopy with structured illumination
    Nenad Bozinovic
    Department of Biomedical Engineering, Boston University, 44 Cummington St, Boston, MA 02215, USA
    Opt Express 16:8016-25. 2008
  7. ncbi request reprint Dynamic speckle illumination microscopy with translated versus randomized speckle patterns
    Cathie Ventalon
    Boston University, Department of Biomedical Engineering, 44 Cummington St, Boston, MA 02215, USA
    Opt Express 14:7198-209. 2006
  8. ncbi request reprint Rejection of two-photon fluorescence background in thick tissue by differential aberration imaging
    Aymeric Leray
    Department of Biomedical Engineering, Boston University, 44 Cummington St, Boston, MA 02215, USA
    Opt Express 14:10565-73. 2006
  9. ncbi request reprint Dynamic speckle illumination microscopy with wavelet prefiltering
    Cathie Ventalon
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts 02215, USA
    Opt Lett 32:1417-9. 2007
  10. pmc Two-photon imaging of spatially extended neuronal network dynamics with high temporal resolution
    Kyle P Lillis
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, United States
    J Neurosci Methods 172:178-84. 2008

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Nonlinear microscopy: new techniques and applications
    Jerome Mertz
    Boston University, Department of Biomedical Engineering, 44 Cummington Street, Boston, Massachusetts 02215, USA
    Curr Opin Neurobiol 14:610-6. 2004
    ..Along with novel strategies to image over exceptionally long durations and with increased depth penetration in living brains, these advances are opening new opportunities in neurobiology that were previously unavailable...
  2. pmc Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection
    Jerome Mertz
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts 02215, USA
    J Biomed Opt 15:016027. 2010
    ....
  3. doi request reprint Widefield fluorescence sectioning with HiLo microscopy
    Jerome Mertz
    Boston University, Department of Biomedical Engineering, 44 Cummington St, Boston, MA, 02215, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:3229-30. 2009
    ..We discuss the theory of this technique and a variety of practical implementations in brain-tissue imaging and fluorescence endomicroscopy...
  4. doi request reprint Optical sectioning microscopy with planar or structured illumination
    Jerome Mertz
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA
    Nat Methods 8:811-9. 2011
    ..In this Review, I examine two such techniques, based on planar illumination or structured illumination. The goal is to describe the advantages and disadvantages of these techniques...
  5. ncbi request reprint Wide-field fluorescence sectioning with hybrid speckle and uniform-illumination microscopy
    Daryl Lim
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Opt Lett 33:1819-21. 2008
    ..This hybrid illumination method is fast, robust, and generalizable to a variety of illumination and imaging configurations...
  6. ncbi request reprint Fluorescence endomicroscopy with structured illumination
    Nenad Bozinovic
    Department of Biomedical Engineering, Boston University, 44 Cummington St, Boston, MA 02215, USA
    Opt Express 16:8016-25. 2008
    ..To establish the potential of our endomicroscope for preclinical or clinical applications, we provide images of BCECF-AM labeled rat colonic mucosa...
  7. ncbi request reprint Dynamic speckle illumination microscopy with translated versus randomized speckle patterns
    Cathie Ventalon
    Boston University, Department of Biomedical Engineering, 44 Cummington St, Boston, MA 02215, USA
    Opt Express 14:7198-209. 2006
    ..We present a theory valid for arbitrary point-spread-functions, which we corroborate with experimental results...
  8. ncbi request reprint Rejection of two-photon fluorescence background in thick tissue by differential aberration imaging
    Aymeric Leray
    Department of Biomedical Engineering, Boston University, 44 Cummington St, Boston, MA 02215, USA
    Opt Express 14:10565-73. 2006
    ..We present a heuristic description of our technique, which we corroborate with experiment. An added benefit of our technique is that it leads to somewhat improved image resolution...
  9. ncbi request reprint Dynamic speckle illumination microscopy with wavelet prefiltering
    Cathie Ventalon
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts 02215, USA
    Opt Lett 32:1417-9. 2007
    ..The resultant gain in sectioning strength leads to a fundamentally improved scaling law for the out-of-focus background rejection...
  10. pmc Two-photon imaging of spatially extended neuronal network dynamics with high temporal resolution
    Kyle P Lillis
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, United States
    J Neurosci Methods 172:178-84. 2008
    ..Finally, we provide the code to make our technique generally available...
  11. ncbi request reprint Enhanced weak-signal sensitivity in two-photon microscopy by adaptive illumination
    Kengyeh K Chu
    Department of Biomedical Engineering, Boston University, MA 02215, USA
    Opt Lett 32:2846-8. 2007
    ..We analyze and demonstrate the benefits of adaptive illumination in two-photon fluorescence microscopy...
  12. ncbi request reprint Autoconfocal microscopy with a cw laser and thermionic detection
    Daryl Lim
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Opt Lett 33:1345-7. 2008
    ..Our technique of thermionic-detection autoconfocal microscopy is further implemented with graded-field contrast to obtain enhanced phase-gradient sensitivity in unlabeled samples, such as rat hippocampal brain slices...

Research Grants6

  1. Thick tissue imaging with auto-confocal microscopy
    Jerome Mertz; Fiscal Year: 2004
    ..abstract_text> ..
  2. Deep ultraviolet nonlinear microscopy in thick tissue
    Jerome Mertz; Fiscal Year: 2006
    ..Ultimately, we hope to confirm our hypothesis that intrinsic optical signals in the DUV spectral window, which has largely been overlooked so far, can provide useful and clinically relevant information. ..
  3. Widefield fluorescence macroscopy with out-of-focus blur rejection
    Jerome Mertz; Fiscal Year: 2007
    ..Our goal is to build a new tool for cancer research that can eventually be implemented in the clinic. ..
  4. The development of hybrid widefield imaging for out-of-focus background rejection
    JEROME C MERTZ; Fiscal Year: 2010
    ..We propose to develop an endomicroscope and a widefield macroscope based on this technology for pre-clinical small-animal cancer-model imaging and diagnosis. ..