Jared W Magnani

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Electrocardiographic PR interval and adverse outcomes in older adults: the Health, Aging, and Body Composition study
    Jared W Magnani
    Cardiology Section, Whitaker Cardiovascular Institute, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Circ Arrhythm Electrophysiol 6:84-90. 2013
  2. pmc Development and application of a longitudinal electrocardiogram repository: the Framingham Heart Study
    Jared W Magnani
    National Heart, Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, MA, USA
    J Electrocardiol 45:673-6. 2012
  3. pmc Age of natural menopause and atrial fibrillation: the Framingham Heart Study
    Jared W Magnani
    National Heart, Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, MA, USA
    Am Heart J 163:729-34. 2012
  4. pmc P wave indices, obesity, and the metabolic syndrome: the atherosclerosis risk in communities study
    Jared W Magnani
    Department of Medicine, Section of Cardiovascular Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    Obesity (Silver Spring) 20:666-72. 2012
  5. pmc P wave duration is associated with cardiovascular and all-cause mortality outcomes: the National Health and Nutrition Examination Survey
    Jared W Magnani
    Boston University School of Medicine, Section of Cardiovascular Medicine, Boston, Massachusetts, USA
    Heart Rhythm 8:93-100. 2011
  6. pmc P wave duration and risk of longitudinal atrial fibrillation in persons ≥ 60 years old (from the Framingham Heart Study)
    Jared W Magnani
    Section of Cardiovascular Medicine, Boston University School of Medicine, Boston, MA, USA
    Am J Cardiol 107:917-921.e1. 2011
  7. pmc Risk assessment for incident heart failure in individuals with atrial fibrillation
    Renate B Schnabel
    NHLBI s and Boston University s Framingham Heart Study, Framingham, MA, USA
    Eur J Heart Fail 15:843-9. 2013
  8. ncbi request reprint Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study
    Jared W Magnani
    National Heart, Lung, and Blood Institute s and Boston University s Framingham Heart Study, Boston, MA
    Circ Arrhythm Electrophysiol 7:307-12. 2014
  9. ncbi request reprint Galectin 3 and incident atrial fibrillation in the community
    Jennifer E Ho
    Boston University and the National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA Section of Cardiovascular Medicine, Department of Medicine, Boston University, Boston, MA Electronic address
    Am Heart J 167:729-734.e1. 2014
  10. pmc Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation
    Moritz F Sinner
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Am J Cardiol 111:219-24. 2013

Detail Information

Publications31

  1. pmc Electrocardiographic PR interval and adverse outcomes in older adults: the Health, Aging, and Body Composition study
    Jared W Magnani
    Cardiology Section, Whitaker Cardiovascular Institute, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Circ Arrhythm Electrophysiol 6:84-90. 2013
    ..We sought to determine the associations between PR interval and heart failure, AF, and mortality in a biracial cohort of older adults...
  2. pmc Development and application of a longitudinal electrocardiogram repository: the Framingham Heart Study
    Jared W Magnani
    National Heart, Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, MA, USA
    J Electrocardiol 45:673-6. 2012
    ..Such a resource will complement the phenotypic and genotypic characterization of FHS, facilitating novel investigations of cardiovascular epidemiology...
  3. pmc Age of natural menopause and atrial fibrillation: the Framingham Heart Study
    Jared W Magnani
    National Heart, Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, MA, USA
    Am Heart J 163:729-34. 2012
    ..Relations between menopausal age and atrial fibrillation (AF) have not been investigated. We examined the association between menopausal age and AF...
  4. pmc P wave indices, obesity, and the metabolic syndrome: the atherosclerosis risk in communities study
    Jared W Magnani
    Department of Medicine, Section of Cardiovascular Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    Obesity (Silver Spring) 20:666-72. 2012
    ..P wave indices may comprise intermediate markers, independent of age and cardiovascular risk, of the pathway linking obesity and with the risk of atrial fibrillation (AF)...
  5. pmc P wave duration is associated with cardiovascular and all-cause mortality outcomes: the National Health and Nutrition Examination Survey
    Jared W Magnani
    Boston University School of Medicine, Section of Cardiovascular Medicine, Boston, Massachusetts, USA
    Heart Rhythm 8:93-100. 2011
    ..P wave indices are an intermediate phenotype modulated by atrial conduction and electrophysiology. Their clinical correlates and association with all-cause mortality have received limited scrutiny...
  6. pmc P wave duration and risk of longitudinal atrial fibrillation in persons ≥ 60 years old (from the Framingham Heart Study)
    Jared W Magnani
    Section of Cardiovascular Medicine, Boston University School of Medicine, Boston, MA, USA
    Am J Cardiol 107:917-921.e1. 2011
    ..In conclusion, maximum P wave duration at the upper fifth percentile was associated with long-term AF risk in an elderly community-based cohort. P wave duration is an electrocardiographic endophenotype for AF...
  7. pmc Risk assessment for incident heart failure in individuals with atrial fibrillation
    Renate B Schnabel
    NHLBI s and Boston University s Framingham Heart Study, Framingham, MA, USA
    Eur J Heart Fail 15:843-9. 2013
    ..Risk factors that predict HF in individuals with AF in the community are not well established...
  8. ncbi request reprint Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study
    Jared W Magnani
    National Heart, Lung, and Blood Institute s and Boston University s Framingham Heart Study, Boston, MA
    Circ Arrhythm Electrophysiol 7:307-12. 2014
    ..Endogenous sex hormones have been related to cardiovascular outcomes and mortality. We hypothesized that sex hormones are related to atrial fibrillation (AF) in a community-based cohort of middle-aged to older men...
  9. ncbi request reprint Galectin 3 and incident atrial fibrillation in the community
    Jennifer E Ho
    Boston University and the National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA Section of Cardiovascular Medicine, Department of Medicine, Boston University, Boston, MA Electronic address
    Am Heart J 167:729-734.e1. 2014
    ..The same mechanisms that lead to cardiac fibrosis in heart failure may influence development of atrial fibrosis and atrial fibrillation (AF). We examined the association of Gal-3 and incident AF in the community...
  10. pmc Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation
    Moritz F Sinner
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Am J Cardiol 111:219-24. 2013
    ..In conclusion, elevated transaminase concentrations are associated with increased AF incidence. The mechanisms by which higher mean transaminase concentrations are associated with incident AF remain to be determined...
  11. pmc Insulin resistance and atrial fibrillation (from the Framingham Heart Study)
    Joao D Fontes
    National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts, USA
    Am J Cardiol 109:87-90. 2012
    ..18, 95% confidence interval 0.84 to 1.65, p = 0.34). In a community-based cohort with ≤10 years of follow-up, no significant association was observed between insulin resistance and incident AF...
  12. pmc Dietary factors and incident atrial fibrillation: the Framingham Heart Study
    Jian Shen
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    Am J Clin Nutr 93:261-6. 2011
    ..There have been conflicting reported associations between dietary factors and incident atrial fibrillation (AF)...
  13. pmc White blood cell count and risk of incident atrial fibrillation (from the Framingham Heart Study)
    Michiel Rienstra
    Cardiovascular Research Center, Massachusetts General Hospital, Boston, USA
    Am J Cardiol 109:533-7. 2012
    ..In conclusion, in our community-based sample, an increased WBC count was associated with incident AF during 5 years of follow-up. Our findings provide additional evidence for the relation between systemic inflammation and AF...
  14. pmc P-wave indices: derivation of reference values from the Framingham Heart Study
    Jared W Magnani
    Section of Cardiovascular Medicine, Boston University School of Medicine, Boston, MA, USA
    Ann Noninvasive Electrocardiol 15:344-52. 2010
    ..Reference values for P-wave indices, providing cut points for their classification and interpretation, have not yet been established and are essential toward facilitating clinical application and comparison between studies...
  15. ncbi request reprint Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese
    Steven A Lubitz
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts Electronic address
    J Am Coll Cardiol 63:1200-10. 2014
    ..This study sought to identify nonredundant atrial fibrillation (AF) genetic susceptibility signals and examine their cumulative relations with AF risk...
  16. pmc Relation of hypothyroidism and incident atrial fibrillation (from the Framingham Heart Study)
    Eun Jeong Kim
    Department of Medicine, Boston University School of Medicine, Boston, MA
    Am Heart J 167:123-6. 2014
    ..Hypothyroidism is associated with cardiovascular risk factors, subclinical cardiovascular disease, and overt cardiovascular disease, all of which predispose to AF. We investigated 10-year incidence of AF in a community-dwelling cohort...
  17. pmc Atrial fibrillation patterns and risks of subsequent stroke, heart failure, or death in the community
    Steven A Lubitz
    Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA
    J Am Heart Assoc 2:e000126. 2013
    ..We developed a novel AF classification algorithm and examined AF patterns and outcomes in the community...
  18. pmc Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project
    Renate B Schnabel
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    Circ Cardiovasc Genet 4:557-64. 2011
    ..The genetic background of atrial fibrillation (AF) in whites and African Americans is largely unknown. Genes in cardiovascular pathways have not been systematically investigated...
  19. ncbi request reprint Targeted sequencing in candidate genes for atrial fibrillation: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study
    Honghuang Lin
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts The NHLBI s Framingham Heart Study, Framingham, Massachusetts Electronic address
    Heart Rhythm 11:452-7. 2014
    ..Genome-wide association studies (GWAS) have identified common genetic variants that predispose to atrial fibrillation (AF). It is unclear whether rare and low-frequency variants in genes implicated by such GWAS confer additional risk of AF...
  20. pmc Reciprocal relations between physical disability, subjective health, and atrial fibrillation: the Framingham Heart Study
    Michiel Rienstra
    Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Am Heart J 166:171-8. 2013
    ..We sought to understand whether AF predisposes to or is a result of physical disability and poor subjective health in the community...
  21. pmc Association between familial atrial fibrillation and risk of new-onset atrial fibrillation
    Steven A Lubitz
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    JAMA 304:2263-9. 2010
    ..Although the heritability of atrial fibrillation (AF) is established, the contribution of familial AF to predicting new-onset AF remains unknown...
  22. pmc Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study
    Renate B Schnabel
    Framingham Heart Study, Framingham, MA, USA Department of Medicine II, Johannes Gutenberg University, Mainz, Germany
    Lancet 373:739-45. 2009
    ..We aimed to develop a risk score to predict individuals' absolute risk of developing the condition, and to provide a framework for researchers to assess new risk markers...
  23. pmc Vitamin D status is not related to development of atrial fibrillation in the community
    Michiel Rienstra
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA, USA
    Am Heart J 162:538-41. 2011
    ..Vitamin D is an emerging risk factor in cardiovascular disease, and vitamin D status is modifiable. Thus, we sought to investigate whether vitamin D status predisposed to the development of AF in a community-based sample...
  24. doi request reprint Genetic Loci associated with atrial fibrillation: relation to left atrial structure in the Framingham Heart Study
    Jared W Magnani
    National Heart, Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, MA
    J Am Heart Assoc 3:e000616. 2014
    ..We sought to investigate associations between single nucleotide polymorphisms (SNPs) and atrial structure obtained by cardiovascular imaging in the Framingham Heart Study...
  25. ncbi request reprint Whole blood gene expression and atrial fibrillation: the Framingham Heart Study
    Honghuang Lin
    Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts, United States of America
    PLoS ONE 9:e96794. 2014
    ..Atrial fibrillation (AF) involves substantial electrophysiological, structural and contractile remodeling. We hypothesize that characterizing gene expression might uncover important pathways related to AF...
  26. pmc Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community
    Renate B Schnabel
    National Heart, Lung, and Blood Institute s and Boston University s Framingham Study, Framingham, Mass, USA
    Circulation 121:200-7. 2010
    ..Biomarkers of multiple pathophysiological pathways have been related to incident atrial fibrillation (AF), but their predictive ability remains controversial...
  27. pmc P-wave indices, distribution and quality control assessment (from the Framingham Heart Study)
    Jared W Magnani
    Boston University School of Medicine, Section of Cardiology, School of Public Health, Boston, MA 01702 5827, USA
    Ann Noninvasive Electrocardiol 15:77-84. 2010
    ..We therefore sought to determine the reproducibility of P-wave indices in a community-based cohort...
  28. pmc Meta-analysis identifies six new susceptibility loci for atrial fibrillation
    Patrick T Ellinor
    Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Nat Genet 44:670-5. 2012
    ..The identified loci implicate candidate genes that encode transcription factors related to cardiopulmonary development, cardiac-expressed ion channels and cell signaling molecules...
  29. doi request reprint Gene expression and genetic variation in human atria
    Honghuang Lin
    National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts Electronic address
    Heart Rhythm 11:266-71. 2014
    ..The human left and right atria have different susceptibilities to develop atrial fibrillation (AF). However, the molecular events related to structural and functional changes that enhance AF susceptibility are still poorly understood...
  30. pmc Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction
    Nona Sotoodehnia
    Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA
    Nat Genet 42:1068-76. 2010
    ..These findings extend our current knowledge of ventricular depolarization and conduction...
  31. ncbi request reprint Assessment of reproducibility - automated and digital caliper ECG measurement in the Framingham Heart Study
    Gordon M Burke
    Department of Medicine, Boston University Medical Center, Boston, MA, USA
    J Electrocardiol 47:288-93. 2014
    ..We recently established an ECG repository of digitally recorded ECGs for the Framingham Heart Study and we sought to assess the reproducibility of automated and manual measures...