Chen Lu

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Pathway analysis following association study
    Julius S Ngwa
    Department of Biostatistics, School of Public Health, Boston University, 715 Albany Street, Boston, MA 02118, USA
    BMC Proc 5:S18. 2011
  2. pmc Network-guided sparse regression modeling for detection of gene-by-gene interactions
    Chen Lu
    Department of Biostatistics, Boston University School of Public Health, Pulmonary Center, Department of Medicine and Department of Neurology, Boston University School of Medicine, Boston, MA, USA
    Bioinformatics 29:1241-9. 2013

Collaborators

  • Julius S Ngwa
  • Wei V Zhuang
  • Anita L Destefano
  • Alisa K Manning
  • Jonna L Grimsby

Detail Information

Publications2

  1. pmc Pathway analysis following association study
    Julius S Ngwa
    Department of Biostatistics, School of Public Health, Boston University, 715 Albany Street, Boston, MA 02118, USA
    BMC Proc 5:S18. 2011
    ..The empirical enrichment method had lower power and higher type I error. Thus pathway analysis approaches may be useful in identifying biological pathways that influence disease outcomes...
  2. pmc Network-guided sparse regression modeling for detection of gene-by-gene interactions
    Chen Lu
    Department of Biostatistics, Boston University School of Public Health, Pulmonary Center, Department of Medicine and Department of Neurology, Boston University School of Medicine, Boston, MA, USA
    Bioinformatics 29:1241-9. 2013
    ..We propose a novel approach to detect such interactions that uses penalized regression and sparse estimation principles, and incorporates outside biological knowledge through a network-based penalty...