David Levin

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Identification of positive regulators of the yeast fps1 glycerol channel
    Sara E Beese
    Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
    PLoS Genet 5:e1000738. 2009
  2. pmc Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway
    David E Levin
    Department of Molecular and Cell Biology, Goldman School of Dental Medicine, Boston University, Boston, Massachusetts 02118, USA
    Genetics 189:1145-75. 2011

Research Grants

  1. RIN1, A NOVEL RAS-INHIBITORY PROTEIN IN YEAST
    David Levin; Fiscal Year: 2006
  2. Cell Wall Integrity Signaling in Yeast
    David Levin; Fiscal Year: 2007
  3. Cell Wall Integrity Signaling in Yeast
    David Levin; Fiscal Year: 2009
  4. PROTEIN KINASE C IN YEAST GROWTH CONTROL
    David Levin; Fiscal Year: 2003
  5. ROLE OF PROTEIN KINASE C IN YEAST GROWTH CONTROL
    David Levin; Fiscal Year: 1993
  6. PROTEIN KINASE C AND YEAST GROWTH CONTROL
    David Levin; Fiscal Year: 1999
  7. Cell Wall Integrity Signaling in Yeast
    David E Levin; Fiscal Year: 2010

Collaborators

  • Sara E Beese
  • Takahiro Negishi

Detail Information

Publications2

  1. pmc Identification of positive regulators of the yeast fps1 glycerol channel
    Sara E Beese
    Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
    PLoS Genet 5:e1000738. 2009
    ..This stress-induced phosphorylation was partially dependent on the Hog1 MAPK. Hog1 was also required for basal phosphorylation of Rgc2, suggesting a mechanism by which Hog1 may regulate Fps1 indirectly...
  2. pmc Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway
    David E Levin
    Department of Molecular and Cell Biology, Goldman School of Dental Medicine, Boston University, Boston, Massachusetts 02118, USA
    Genetics 189:1145-75. 2011
    ..The interface of this signaling pathway with other pathways that contribute to the maintenance of cell wall integrity is also discussed...

Research Grants22

  1. RIN1, A NOVEL RAS-INHIBITORY PROTEIN IN YEAST
    David Levin; Fiscal Year: 2006
    ..These experiments will help to test the applicant's model of Rin1 function as an inhibitor of Ras signaling in the ER. ..
  2. Cell Wall Integrity Signaling in Yeast
    David Levin; Fiscal Year: 2007
    ..We have identified two redundant proteins whose loss of function results in cell lysis. We propose a multifaceted approach to establishing their role in the maintenance of cell wall integrity. ..
  3. Cell Wall Integrity Signaling in Yeast
    David Levin; Fiscal Year: 2009
    ..We have identified two redundant proteins whose loss of function results in cell lysis. We propose a multifaceted approach to establishing their role in the maintenance of cell wall integrity. ..
  4. PROTEIN KINASE C IN YEAST GROWTH CONTROL
    David Levin; Fiscal Year: 2003
    ..These results implicate Ypk1/2 in the regulation of phosphoinositides at the plasma membrane. The level at which this regulation takes place will be explored. ..
  5. ROLE OF PROTEIN KINASE C IN YEAST GROWTH CONTROL
    David Levin; Fiscal Year: 1993
    ..Other known cell lysis mutants will also be examined for genetic interactions with PKC1 and BCK1...
  6. PROTEIN KINASE C AND YEAST GROWTH CONTROL
    David Levin; Fiscal Year: 1999
    ..Novel signaling components will be identified through synthetic lethal and suppressor screens using a conditional allele of the SIT4 gene, which encodes a Pl-4 kinase that has been implicated in PKC1 signaling. ..
  7. Cell Wall Integrity Signaling in Yeast
    David E Levin; Fiscal Year: 2010
    ..Proposed studies are likely to reveal suitable molecular targets for the development of antifungal agents that display selective toxicity against fungal cells. ..