Timothy Lash

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint Heuristic thinking and inference from observational epidemiology
    Timothy L Lash
    Boston University School of Public Health, Boston, MA, USA
    Epidemiology 18:67-72. 2007
  2. ncbi request reprint Advanced age and adjuvant tamoxifen prescription in early-stage breast carcinoma patients
    Sarah B Blackman
    Geriatrics Health Services Research Unit, Boston Medical Center, Boston, Massachusetts 02118, USA
    Cancer 95:2465-72. 2002
  3. doi request reprint Tamoxifen treatment in Danish breast cancer patients and 5-year risk of arterial atherosclerotic events: a null association
    Rohini K Hernandez
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Cancer Epidemiol Biomarkers Prev 17:2509-11. 2008
  4. pmc Collapsing high-end categories of comorbidity may yield misleading results
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
    Clin Epidemiol 1:11-5. 2009
  5. pmc Prescriptions for selective cyclooxygenase-2 inhibitors, non-selective non-steroidal anti-inflammatory drugs, and risk of breast cancer in a population-based case-control study
    Deirdre P Cronin-Fenton
    Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Alle 43 45, Aarhus N, Denmark
    Breast Cancer Res 12:R15. 2010
  6. pmc Digoxin treatment is associated with an increased incidence of breast cancer: a population-based case-control study
    Thomas P Ahern
    Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Alle 43 45, 8200 Aarhus N, Denmark
    Breast Cancer Res 10:R102. 2008
  7. pmc Triple-negative breast cancers are increased in black women regardless of age or body mass index
    Lesley A Stead
    Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA
    Breast Cancer Res 11:R18. 2009
  8. pmc Use of selective serotonin reuptake inhibitors and risk of re-operation due to post-surgical bleeding in breast cancer patients: a Danish population-based cohort study
    Rune Gärtner
    Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Alle 43 45, Aarhus N 8200, Denmark
    BMC Surg 10:3. 2010
  9. pmc Risk of Parkinson's disease after tamoxifen treatment
    Jeanne C Latourelle
    Department of Neurology, Boston University School of Medicine, 85 East Concord Street, Boston, MA 02118, USA
    BMC Neurol 10:23. 2010
  10. pmc Automated inter-rater reliability assessment and electronic data collection in a multi-center breast cancer study
    Soe Soe Thwin
    Geriatrics Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    BMC Med Res Methodol 7:23. 2007

Detail Information

Publications74

  1. ncbi request reprint Heuristic thinking and inference from observational epidemiology
    Timothy L Lash
    Boston University School of Public Health, Boston, MA, USA
    Epidemiology 18:67-72. 2007
    ..The methods that quantify systematic error and uncertainty challenge the analyst to specify the alternative explanations for associations that are otherwise too readily judged causal...
  2. ncbi request reprint Advanced age and adjuvant tamoxifen prescription in early-stage breast carcinoma patients
    Sarah B Blackman
    Geriatrics Health Services Research Unit, Boston Medical Center, Boston, Massachusetts 02118, USA
    Cancer 95:2465-72. 2002
    ..We investigated age-dependent variations in adjuvant tamoxifen prescription patterns in a cohort of women 80 years of age and older...
  3. doi request reprint Tamoxifen treatment in Danish breast cancer patients and 5-year risk of arterial atherosclerotic events: a null association
    Rohini K Hernandez
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Cancer Epidemiol Biomarkers Prev 17:2509-11. 2008
    ..These findings are important in risk/benefit analyses as tamoxifen therapy in postmenopausal women is being replaced with aromatase inhibitors...
  4. pmc Collapsing high-end categories of comorbidity may yield misleading results
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
    Clin Epidemiol 1:11-5. 2009
    ....
  5. pmc Prescriptions for selective cyclooxygenase-2 inhibitors, non-selective non-steroidal anti-inflammatory drugs, and risk of breast cancer in a population-based case-control study
    Deirdre P Cronin-Fenton
    Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Alle 43 45, Aarhus N, Denmark
    Breast Cancer Res 12:R15. 2010
    ....
  6. pmc Digoxin treatment is associated with an increased incidence of breast cancer: a population-based case-control study
    Thomas P Ahern
    Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Alle 43 45, 8200 Aarhus N, Denmark
    Breast Cancer Res 10:R102. 2008
    ..We explored the association between digoxin treatment and invasive breast cancer incidence among postmenopausal Danish women...
  7. pmc Triple-negative breast cancers are increased in black women regardless of age or body mass index
    Lesley A Stead
    Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA
    Breast Cancer Res 11:R18. 2009
    ..We focused on triple-negative (Tneg) tumours (oestrogen receptor (ER), progesterone receptor (PR) and HER2 negative), which are associated with poor prognosis...
  8. pmc Use of selective serotonin reuptake inhibitors and risk of re-operation due to post-surgical bleeding in breast cancer patients: a Danish population-based cohort study
    Rune Gärtner
    Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Alle 43 45, Aarhus N 8200, Denmark
    BMC Surg 10:3. 2010
    ..Selective serotonin reuptake inhibitors (SSRI) decrease platelet-function, which suggests that SSRI use may increase the risk of post-surgical bleeding. Few studies have investigated this potential association...
  9. pmc Risk of Parkinson's disease after tamoxifen treatment
    Jeanne C Latourelle
    Department of Neurology, Boston University School of Medicine, 85 East Concord Street, Boston, MA 02118, USA
    BMC Neurol 10:23. 2010
    ..We compared the rate of PD in Danish breast cancer patients treated with tamoxifen to the rate among those not treated with tamoxifen...
  10. pmc Automated inter-rater reliability assessment and electronic data collection in a multi-center breast cancer study
    Soe Soe Thwin
    Geriatrics Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
    BMC Med Res Methodol 7:23. 2007
    ..There remains a need to examine potential benefits, efficiencies, and innovations associated with an EDC system in a multi-center medical record review study...
  11. pmc Prognosis of ovarian cancer subsequent to venous thromboembolism: a nationwide Danish cohort study
    Mette S Tetsche
    Department of Clinical Epidemiology, Aarhus University Hospital, 8000 Aarhus, Denmark
    BMC Cancer 6:189. 2006
    ..Our aims were to examine the extent of disease at the time of the diagnosis of ovarian cancer and to estimate the impact of VTE on survival of ovarian cancer...
  12. pmc Bias analysis applied to Agricultural Health Study publications to estimate non-random sources of uncertainty
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, 715 Albany St, TE3, Boston, MA, USA
    J Occup Med Toxicol 2:15. 2007
    ....
  13. pmc A case-only analysis of the interaction between N-acetyltransferase 2 haplotypes and tobacco smoke in breast cancer etiology
    Timothy L Lash
    Boston University School of Public Health, Boston, MA, USA
    Breast Cancer Res 7:R385-93. 2005
    ..We hypothesized that women with breast cancer who were slow acetylators would be at increased risk of breast cancer associated with active and passive exposure to tobacco smoke...
  14. ncbi request reprint Using probabilistic corrections to account for abstractor agreement in medical record reviews
    Timothy L Lash
    Boston University School of Public Health, Boston, MA 02118, USA
    Am J Epidemiol 165:1454-61. 2007
    ..While many investigators use reliability data only as a metric for data quality, a more thorough approach can also quantitatively depict the uncertainty in the observed associations...
  15. ncbi request reprint Physicians' assessments of adjuvant tamoxifen's effectiveness in older patients with primary breast cancer
    Timothy L Lash
    Department of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts, USA
    J Am Geriatr Soc 53:1889-96. 2005
    ..To examine physicians' assessments of tamoxifen effectiveness in breast cancer patients, identify predictors of these assessments, and estimate the relationship between these assessments and receipt of tamoxifen prescription...
  16. ncbi request reprint Reduced mortality rate associated with annual mammograms after breast cancer therapy
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts 02118, USA
    Breast J 12:2-6. 2006
    ..77 (95% confidence interval [CI] 0.53-1.1). These results are consistent with a protective effect of regular surveillance mammography after completing therapy for early stage breast cancer...
  17. pmc Departure from multiplicative interaction for catechol-O-methyltransferase genotype and active/passive exposure to tobacco smoke among women with breast cancer
    Brian D Bradbury
    Department of Epidemiology, Boston University School of Public Health, 715 Albany St, T3E, Boston, MA 02118, USA
    J Carcinog 5:3. 2006
    ..8, 10). CONCLUSION : With greater control over potential misclassification errors and a large case-only population, we found evidence to support an interaction between COMT genotype and tobacco smoke exposure in breast cancer etiology...
  18. ncbi request reprint Adherence to tamoxifen over the five-year course
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Breast Cancer Res Treat 99:215-20. 2006
    ..To estimate the proportion of older women who fail to complete 5 years of tamoxifen therapy and to identify predictors of non-adherence...
  19. ncbi request reprint Mammography surveillance and mortality in older breast cancer survivors
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    J Clin Oncol 25:3001-6. 2007
    ..Our purpose is to estimate the effectiveness of surveillance mammography in a cohort of breast cancer survivors with complete ascertainment of surveillance mammograms and negligible losses to follow-up...
  20. pmc Tamoxifen's protection against breast cancer recurrence is not reduced by concurrent use of the SSRI citalopram
    T L Lash
    Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA
    Br J Cancer 99:616-21. 2008
    ..These results suggest that concurrent use of citalopram does not reduce tamoxifen's prevention of breast cancer recurrence...
  21. ncbi request reprint Patient characteristics and treatments associated with a decline in upper-body function following breast cancer therapy
    T L Lash
    Boston University School of Public Health, Boston, MA 02118, USA
    J Clin Epidemiol 53:615-22. 2000
    ..2-33) at the 21-month interview than women who did not. Clinicians should consider the functional consequences of treatment when discussing treatment options and postoperative care with women who have early stage breast cancer...
  22. pmc Methodology, design, and analytic techniques to address measurement of comorbid disease
    Timothy L Lash
    Geriatrics Section, Boston University School of Medicine, Boston, MA 02118, USA
    J Gerontol A Biol Sci Med Sci 62:281-5. 2007
    ..Comorbidity measurement particularly affects research involving older adults because they bear the disproportionate share of the comorbidity burden...
  23. ncbi request reprint A null association between active or passive cigarette smoking and breast cancer risk
    Timothy L Lash
    Boston University School of Public Health, MA, USA
    Breast Cancer Res Treat 75:181-4. 2002
    ..55-0.95) nor ever-passive smoking (adjusted OR = 0.85, 95% CI 0.63-1.1) were strongly associated with breast cancer risk compared with never-active never-passive smoking. No patterns of effects were observed in subgroup analyses...
  24. ncbi request reprint Semi-automated sensitivity analysis to assess systematic errors in observational data
    Timothy L Lash
    Boston University School of Public Health, MA, USA
    Epidemiology 14:451-8. 2003
    ..Published epidemiologic research usually provides a quantitative assessment of random error for effect estimates, but no quantitative assessment of systematic error. Sensitivity analysis can provide such an assessment...
  25. ncbi request reprint Null association between pregnancy termination and breast cancer in a registry-based study of parous women
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA
    Int J Cancer 110:443-8. 2004
    ..68; 95% CI = 0.45-1.03), suggesting a protective effect of terminated pregnancy among women with one live birth...
  26. pmc Genotype-guided tamoxifen therapy: time to pause for reflection?
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Lancet Oncol 10:825-33. 2009
    ..We argue that a recommendation for CYP2D6 genotyping of candidates for tamoxifen therapy, and its implicit conclusion regarding the association between genotype and recurrence risk, is premature...
  27. ncbi request reprint Reduced rates of cancer-related worries and mortality associated with guideline surveillance after breast cancer therapy
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA
    Breast Cancer Res Treat 89:61-7. 2005
    ..The objective of this investigation was to assess the impact of guideline surveillance (history, physical examination, and annual mammography) on cancer-related worries and all-cause mortality...
  28. ncbi request reprint Medical surveillance after breast cancer diagnosis
    T L Lash
    School of Public Health, Boston University Medical Center, Massachusetts 02118, USA
    Med Care 39:945-55. 2001
    ..To characterize the tests ordered for surveillance of breast cancer recurrence in the 4 years after breast cancer diagnosis by surgeons, medical oncologists, and radiation oncologists...
  29. ncbi request reprint The effect of less than definitive care on breast carcinoma recurrence and mortality
    T L Lash
    Department of Epidemiology and Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA
    Cancer 89:1739-47. 2000
    ..The objective of this study was to measure the effects of less than definitive care for patients with breast carcinoma on disease recurrence and mortality...
  30. ncbi request reprint Tamoxifen-treated breast carcinoma patients and the risk of acute myocardial infarction and newly-diagnosed angina
    Brian D Bradbury
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA
    Cancer 103:1114-21. 2005
    ....
  31. ncbi request reprint Long-term follow-up of upper-body function among breast cancer survivors
    Timothy L Lash
    Department of Epidemiology and Biostatistics, Boston University School of Public Health, Geriatrics Section, Boston Medical Center, Boston, Massachusetts, USA
    Breast J 8:28-33. 2002
    ..8-fold more likely to report that they had recovered their upper-body function at their next interview (95% CI, 2.0, 12). This finding suggests that attention to upper-body function during follow-up visits may facilitate recovery...
  32. pmc Breast cancer recurrence in older women five to ten years after diagnosis
    Jaclyn L F Bosco
    Department of Medicine, Section of Geriatrics, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Cancer Epidemiol Biomarkers Prev 18:2979-83. 2009
    ..This study of late recurrence emphasizes that the risk, although small, is not negligible even in this group at high risk of death due to competing causes...
  33. doi request reprint Association between wind speed and the occurrence of sickle cell acute painful episodes: results of a case-crossover study
    Vikki G Nolan
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Br J Haematol 143:433-8. 2008
    ....
  34. doi request reprint Metformin and incident breast cancer among diabetic women: a population-based case-control study in Denmark
    Jaclyn Lee Fong Bosco
    Section of Geriatrics, Department of Medicine, Boston University School of Medicine, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 20:101-11. 2011
    ..We evaluated the effect of metformin medication on the risk of incident breast cancer among peri- and postmenopausal women...
  35. ncbi request reprint Trends in breast-conserving surgery in Denmark, 1982-2002
    Thomas P Ahern
    Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, TE3, Boston, MA 02118, USA
    Eur J Epidemiol 23:109-14. 2008
    ..By 2002, BCS prevalence appeared to reach a threshold at 25% of breast cancer operations, seemingly defined by the proportion of new breast cancer cases who are good candidates for BCS...
  36. doi request reprint Lifetime tobacco smoke exposure and breast cancer incidence
    Thomas P Ahern
    Department of Epidemiology, Boston University School of Public Health, 715 Albany Street T3E, Boston, MA 02118, USA
    Cancer Causes Control 20:1837-44. 2009
    ..We analyzed data from a case-control study to assess the association between lifetime tobacco smoke exposure and breast cancer incidence...
  37. doi request reprint Tamoxifen treatment and risk of deep venous thrombosis and pulmonary embolism: a Danish population-based cohort study
    Rohini K Hernandez
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA
    Cancer 115:4442-9. 2009
    ..To the authors' knowledge, it is not yet known whether the risk changes with the amount of time elapsed since the initial tamoxifen prescription. This information would be valuable in identifying patients at high risk for DVT/PE...
  38. pmc Impact of acquired comorbidities on all-cause mortality rates among older breast cancer survivors
    Thomas P Ahern
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts 02118, USA
    Med Care 47:73-9. 2009
    ..The effect of time-varying comorbidity status on mortality in breast cancer survivors, however, has not been well investigated...
  39. pmc A most stubborn bias: no adjustment method fully resolves confounding by indication in observational studies
    Jaclyn L F Bosco
    Department of Medicine, Geriatrics Section, Boston University School of Medicine, Boston, MA 02118, USA
    J Clin Epidemiol 63:64-74. 2010
    ..To evaluate the effectiveness of methods that control for confounding by indication, we compared breast cancer recurrence rates among women receiving adjuvant chemotherapy with those who did not...
  40. ncbi request reprint Validating medical students' self-report of smoking-related communication skills and educational experiences
    Katie R Brooks
    Department of Dermatology, Boston University School of Medicine, Boston, Mass, USA
    Ambul Pediatr 7:187-91. 2007
    ..In evaluating an educational intervention that promotes this skill, we assess whether students' self-report of this counseling skill was a valid measure of actual behavior...
  41. ncbi request reprint A sensitivity analysis of a randomized controlled trial of zinc in treatment of falciparum malaria in children
    Matthew P Fox
    Center for International Health and Development, Boston University School of Public Health, 85 East Concord St, 5th Floor, Boston, MA 02118, USA
    Contemp Clin Trials 26:281-9. 2005
    ..We examined the impact of different sources of bias on a randomized controlled trial of the efficacy of zinc as an adjuvant to malaria therapy in reducing time to total parasite clearance...
  42. ncbi request reprint A null association between smoking during pregnancy and breast cancer using Massachusetts registry data (United States)
    Aliza K Fink
    Boston University School of Public Health, MA, USA
    Cancer Causes Control 14:497-503. 2003
    ..An earlier investigation reported a five-fold increase in breast cancer risk among women who smoked during pregnancy. Using a similar design, we re-examined this hypothesis...
  43. ncbi request reprint A method to automate probabilistic sensitivity analyses of misclassified binary variables
    Matthew P Fox
    Department of International Health, Boston University School of Public Health, Boston, MA, USA
    Int J Epidemiol 34:1370-6. 2005
    ..Misclassification bias is present in most studies, yet uncertainty about its magnitude or direction is rarely quantified...
  44. ncbi request reprint Effect of undertreatment on the disparity in age-related breast cancer-specific survival among older women
    Cynthia Owusu
    Hematology and Medical Oncology Section, Department of Medicine, Boston University School of Medicine, Evans Biomedical Research Center, Boston, MA 02118 2393, USA
    Breast Cancer Res Treat 102:227-36. 2007
    ..Assess the relationship between age and breast cancer-specific survival among older women and determine whether the observed age-related disparities in survival is explained by differences in breast cancer treatments received...
  45. ncbi request reprint The primary care pediatrician's influence on medical student's performance of smoking assessments and counseling
    Alan C Geller
    Department of Dermatology, Boston University School of Medicine, 720 Harrison Avenue, DOB 801A, Boston, MA 02118, USA
    Prev Med 41:47-52. 2005
    ....
  46. ncbi request reprint Multiple informants: a new method to assess breast cancer patients' comorbidity
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA
    Am J Epidemiol 157:249-57. 2003
    ....
  47. ncbi request reprint Adjuvant tamoxifen prescription in women 65 years and older with primary breast cancer
    Rebecca A Silliman
    Department of Medicine, Boston University School of Medicine, MA, USA
    J Clin Oncol 20:2680-8. 2002
    ..We examined patterns of adjuvant tamoxifen discussion and prescription among breast cancer patients age 65 years and older...
  48. pmc Predictors and outcomes of surgeons' referral of older breast cancer patients to medical oncologists
    Soe Soe Thwin
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA
    Cancer 104:936-42. 2005
    ..Although coordination of referral among specialists is an important component of quality of care, it has not been studied as a factor that contributes to observed age-related variations in breast cancer care...
  49. pmc No increase in breast cancer recurrence with concurrent use of tamoxifen and some CYP2D6-inhibiting medications
    Thomas P Ahern
    Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, T3E, Boston, MA 02118, USA
    Cancer Epidemiol Biomarkers Prev 18:2562-4. 2009
    ..Together, these results provide evidence for a null association between drug-compromised CYP2D6 activity and breast cancer recurrence among tamoxifen-treated women...
  50. ncbi request reprint Tamoxifen and cataracts: a null association
    Brian D Bradbury
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA
    Breast Cancer Res Treat 87:189-96. 2004
    ..We assessed whether breast cancer patients treated with tamoxifen were at increased risk of developing cataracts compared to women not prescribed tamoxifen...
  51. pmc Hormone replacement therapy, family history, and breast cancer risk among postmenopausal women
    Robert Gramling
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA
    Epidemiology 20:752-6. 2009
    ..We investigated whether the risk difference for invasive breast cancer attributable to estrogen plus progesterone replacement therapy is greater among women with a first-degree family history of the disease...
  52. pmc Predictors of timely follow-up after abnormal cancer screening among women seeking care at urban community health centers
    Tracy A Battaglia
    Women s Health Unit, Section of General Internal Medicine, Department of Medicine, and Women s Health Interdisciplinary Research Center, Boston University School of Medicine, Boston, MA 02118, USA
    Cancer 116:913-21. 2010
    ..We sought to measure time and identify predictors of timely follow-up among a cohort of racially/ethnically diverse inner city women with breast and cervical cancer screening abnormalities...
  53. doi request reprint Posttraumatic stress disorder and completed suicide
    Jaimie L Gradus
    National Center for PTSD, VA Boston Healthcare System, Boston, MA 02130, USA
    Am J Epidemiol 171:721-7. 2010
    ..In conclusion, a registry-based diagnosis of PTSD based on International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, is a risk factor for completed suicide...
  54. pmc Validity of self-reported rheumatoid arthritis in a large cohort: results from the Black Women's Health Study
    Margaret K Formica
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Arthritis Care Res (Hoboken) 62:235-41. 2010
    ....
  55. pmc Risk of decline in upper-body function and symptoms among older breast cancer patients
    Jennifer L Westrup
    Department of Medicine, Boston University School of Medicine, Boston, MA, USA
    J Gen Intern Med 21:327-33. 2006
    ..The long-term risks and predictors are poorly understood...
  56. ncbi request reprint Recurrences and second primary breast cancers in older women with initial early-stage disease
    Ann M Geiger
    Division of Public Health Sciences, Department of Social Sciences and Health Policy, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Cancer 109:966-74. 2007
    ..The association between common breast cancer therapies and recurrences and second primary breast cancers in older women is unclear, although older women are less likely to receive common therapies...
  57. ncbi request reprint NO excess risk of breast cancer among female users of systemic glucocorticoids
    Henrik Toft Sørensen
    Department of Clinical Epidemiology, Aarhus University Hospital, Ole Worms Allé 150, 8000 Aarhus C, Denmark
    Cancer Epidemiol Biomarkers Prev 14:1022-3. 2005
  58. ncbi request reprint Do variations in breast cancer care matter?
    Rebecca A Silliman
    Med Care 40:177-80. 2002
  59. ncbi request reprint Breast cancer in older women: quality of life and psychosocial adjustment in the 15 months after diagnosis
    Patricia A Ganz
    University of California, School of Medicine and Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, 90095 6900, USA
    J Clin Oncol 21:4027-33. 2003
    ..We examined the health-related quality of life (QOL) of a cohort of older women with breast cancer after their diagnosis...
  60. ncbi request reprint Breast cancer, passive and active cigarette smoking and N-acetyltransferase 2 genotype
    Alfredo Morabia
    Pharmacogenetics 12:85-8. 2002
  61. ncbi request reprint Birth outcome in Danish women with cutaneous malignant melanoma
    Vivian Langagergaard
    Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
    Melanoma Res 17:31-6. 2007
    ..7; 12). This estimate was, however, based on only five stillbirths in the exposed group and was an unexpected finding. With this exception, our data suggest no substantially increased risk of adverse birth outcome for women with melanoma...
  62. ncbi request reprint No excess risk of breast cancer in mothers of boys with hypospadias
    Henrik Toft Sørensen
    Epidemiology 17:706-7. 2006
  63. ncbi request reprint Effectiveness of adjuvant tamoxifen therapy among older women with early stage breast cancer
    Cynthia Owusu
    Division of Hematology and Oncology, Department of Medicine, Case Western Reserve University Cleveland, Ohio, USA
    Breast J 13:374-82. 2007
    ..53 (95% CI = 0.37-0.77). Adjuvant tamoxifen is associated with improvement in 5-year breast cancer-specific and overall survival in older women with early-stage breast cancer...
  64. pmc Under utilization of surveillance mammography among older breast cancer survivors
    Terry S Field
    Meyers Primary Care Institute, Worcester, MA 01605, USA
    J Gen Intern Med 23:158-63. 2008
    ..Annual surveillance mammography is recommended for follow-up of women with a history of breast cancer. We examined surveillance mammography among breast cancer survivors who were enrolled in integrated healthcare systems...
  65. ncbi request reprint Survival in Danish patients with breast cancer and inflammatory bowel disease: a nationwide cohort study
    Kirstine Kobberøe Søgaard
    Department of Clinical Epidemiology, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Inflamm Bowel Dis 14:519-25. 2008
    ..The influence of IBD on breast cancer prognosis, however, is unknown. We therefore examined the impact of IBD on treatment receipt and survival in breast cancer patients...
  66. ncbi request reprint Predictors of tamoxifen discontinuation among older women with estrogen receptor-positive breast cancer
    Cynthia Owusu
    Division of Hematology Oncology, Case Western Reserve University, University Hospitals Health System Ireland Cancer Center BHC 5055, 11100 Euclid Ave, Cleveland, OH 44106 5055, USA
    J Clin Oncol 26:549-55. 2008
    ..However, information on tamoxifen discontinuation is scanty. We sought to identify predictors of tamoxifen discontinuation among older women with breast cancer...
  67. ncbi request reprint Mortality impact of less-than-standard therapy in older breast cancer patients
    Marianne Ulcickas Yood
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    J Am Coll Surg 206:66-75. 2008
    ....
  68. doi request reprint Modification of tamoxifen response: what have we learned?
    Timothy L Lash
    J Clin Oncol 26:1764-5; author reply 1765-6. 2008
  69. doi request reprint Comorbidity and survival of Danish cirrhosis patients: a nationwide population-based cohort study
    Peter Jepsen
    Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
    Hepatology 48:214-20. 2008
    ..15). In the first year of follow-up, but not later, comorbidity increased the risk of cirrhosis-related death, and this was consistent with an apparent synergy between the cirrhosis and comorbidity effects on mortality in the same period...
  70. pmc Breast cancer treatment of older women in integrated health care settings
    Shelley M Enger
    Department of Research and Evaluation, Kaiser Permanente Medical Care Program, Pasadena, CA, USA
    J Clin Oncol 24:4377-83. 2006
    ..We sought to identify patient and tumor characteristics associated with the nonreceipt of standard primary tumor and systemic adjuvant therapies...
  71. pmc Comment on 'Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy'
    Timothy L Lash
    Cancer Sci 99:1706-7. 2008
  72. ncbi request reprint Breast cancer survival of American Indian/Alaska Native women, 1973-1996
    Nina S Wampler
    Noqsi Research, Pine, Colorado 80470, USA
    Soz Praventivmed 50:230-7. 2005
    ..To assess breast cancer mortality rates among American Indian/Alaska Native women compared with non-Hispanic White women in the five years after diagnosis...
  73. ncbi request reprint Beyond randomized controlled trials: a critical comparison of trials with nonrandomized studies
    Henrik Toft Sørensen
    Department of Clinical Epidemiology, Aarhus University Hospital, 8000 Aarhus C, Denmark
    Hepatology 44:1075-82. 2006
    ..Observational studies cannot replace trials, nor do trials make observational studies unnecessary. Both designs are susceptible to particular bias, so neither provides perfect information...
  74. pmc Glyphosate results revisited
    Donna R Farmer
    Environ Health Perspect 113:A365-6; author reply A366-7. 2005

Research Grants5

  1. Modification of tamoxifen effectiveness by gene polymorphisms and other drugs
    Timothy Lash; Fiscal Year: 2009
    ..Understanding the modification of tamoxifen effectiveness by genetic polymorphisms or drug interactions will help patients and physicians to make fully informed decisions about hormone therapy. ..
  2. SMOKING & GENETIC INTERACTION IN BREAST CANCER ETIOLOGY
    Timothy Lash; Fiscal Year: 2004
    DESCRIPTION: (Applicant's Description) The candidate, Dr. Timothy Lash, has been committed to cancer research since the beginning of his career...
  3. Modification of tamoxifen effectiveness by gene polymorphisms and other drugs
    Timothy Lash; Fiscal Year: 2007
    ..Understanding the modification of tamoxifen effectiveness by genetic polymorphisms or drug interactions will help patients and physicians to make fully informed decisions about hormone therapy. ..