Research Topics
Species | Jiyoun KimSummaryAffiliation: Boston University Country: USA Publications
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Publications
Diesel exhaust particulates exacerbate asthma-like inflammation by increasing CXC chemokinesJiyoun Kim
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Am J Pathol 179:2730-9. 2011..These results demonstrate that DEP exacerbates airway inflammation induced by allergen through increased pulmonary expression of the CXC chemokines (keratinocyte-derived chemokine and macrophage inflammatory protein-2)...
Herbal medicine treatment reduces inflammation in a murine model of cockroach allergen-induced asthmaJiyoun Kim
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Ann Allergy Asthma Immunol 107:154-62. 2011..A traditional Korean medicine, So-Cheong-Ryong-Tang (SCRT), has been used for the treatment of asthma in Asia for centuries, but its mechanism for reducing bronchopulmonary inflammation in asthma has yet to be elucidated...
Pulmonary endotoxin tolerance protects against cockroach allergen-induced asthma-like inflammation in a mouse modelSudha Natarajan
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA
Int Arch Allergy Immunol 158:120-30. 2012..It is currently unclear how prior inhalation of endotoxin affects allergen sensitization. We examined whether lung-specific endotoxin tolerance induction prior to sensitization can modulate the response to allergen...
Acute oral ethanol exposure triggers asthma in cockroach allergen-sensitized miceJacqueline C Bouchard
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Massachusetts, USA
Am J Pathol 181:845-57. 2012..Together, these data show a single oral alcohol exposure will trigger asthma-like pulmonary inflammation in allergen-sensitized mice, providing a novel asthma model...
Reducing LPS content in cockroach allergens increases pulmonary cytokine production without increasing inflammation: a randomized laboratory studySudha Natarajan
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, 670 Albany Street, 720 Harisson Avenue, Boston, MA 02118, USA
BMC Pulm Med 11:12. 2011....
Chronic pulmonary LPS tolerance induces selective immunosuppression while maintaining the neutrophilic responseSudha Natarajan
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
Shock 33:162-9. 2010..This unrestricted neutrophil recruitment may represent a mechanism by which individuals may be protected from pulmonary bacterial infection and pneumonia...
Cockroach allergens induce biphasic asthma-like pulmonary inflammation in outbred miceLouis J Vaickus
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA
J Asthma 49:510-21. 2012..The aim of this study is to define the kinetics of the pulmonary inflammatory response in cockroach allergen (CRA) sensitized and challenged outbred mice...
Assessing pulmonary pathology by detailed examination of respiratory functionLouis J Vaickus
Department of Pathology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Am J Pathol 177:1861-9. 2010..In conclusion, a detailed examination of WBP parameters can accurately assess the respiratory health of mice and will help direct additional studies...
Inbred and outbred mice have equivalent variability in a cockroach allergen-induced model of asthmaLouis J Vaickus
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Massachusetts, USA
Comp Med 60:420-6. 2010..35 ± 0.34 for BALB mice compared with 0.31 ± 0.32 for ICR mice. In conclusion, inbred BALB and outbred ICR mice have roughly equivalent intrastrain or -stock variability in a murine model of asthma-like pulmonary inflammation...
Oral tolerance inhibits pulmonary eosinophilia in a cockroach allergen induced model of asthma: a randomized laboratory studyLouis J Vaickus
Boston University School of Medicine, Department of Pathology and Laboratory Medicine, Boston, MA, USA
Respir Res 11:160. 2010..In this study we endeavored to induce oral tolerance to cockroach allergen (CRA: a complex mixture of insect components) in order to ameliorate asthma-like, allergic pulmonary inflammation...
Cecal ligation and puncture-induced murine sepsis does not cause lung injuryKendra N Iskander
Department of Surgery, Boston University Medical Center, Boston, MA, USA
Crit Care Med 41:159-70. 2013..The primary purpose of this study was to determine if significant lung injury develops in mice predicted to die after cecal ligation and puncture-induced sepsis compared with those predicted to live...
Acute pulmonary lipopolysaccharide tolerance decreases TNF-alpha without reducing neutrophil recruitmentSudha Natarajan
Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA
J Immunol 181:8402-8. 2008..This response may be a mechanism to limit tissue damage by reducing TNF-alpha levels, while still maintaining the antimicrobial capacity of the lung...
