Gyungah Jun

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes
    Gyungah Jun
    Department of Medicine, Biomedical Genetics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e43728. 2012
  2. pmc Using linkage analysis of large pedigrees to guide association analyses
    Seung Hoan Choi
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston, MA 02118, USA
    BMC Proc 5:S79. 2011
  3. pmc Comprehensive search for Alzheimer disease susceptibility loci in the APOE region
    Gyungah Jun
    Department of Medicine Biomedical Genetics, Boston University Schools of Medicine and Public Health, Boston, MA, USA
    Arch Neurol 69:1270-9. 2012
  4. pmc Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
    Margaux A Morrison
    Ocular Molecular Genetics Institute, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA, USA
    Hum Genomics 5:538-68. 2011
  5. pmc Multiple loci influencing hippocampal degeneration identified by genome scan
    Scott A Melville
    Department of Medicine, Boston University School of Medicine, MA, USA
    Ann Neurol 72:65-75. 2012
  6. doi request reprint A search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways
    Mark W Logue
    Department of Medicine Biomedical Genetics, Boston University School of Medicine, Boston, MA, USA Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    Neurobiol Aging 35:1510.e7-18. 2014
  7. pmc Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology
    Gyungah Jun
    Medicine Biomedical Genetics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 6:e25775. 2011
  8. pmc Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes
    Gyungah Jun
    Department of Medicine, Boston University, USA
    Arch Neurol 67:1473-84. 2010

Collaborators

Detail Information

Publications8

  1. pmc δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes
    Gyungah Jun
    Department of Medicine, Biomedical Genetics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 7:e43728. 2012
    ..Our findings suggest that genetic variation in delta catenin may underlie both cortical lens opacities in mid-life and subsequent MRI and cognitive changes that presage the development of AD...
  2. pmc Using linkage analysis of large pedigrees to guide association analyses
    Seung Hoan Choi
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston, MA 02118, USA
    BMC Proc 5:S79. 2011
    ..5% of the exome. This result suggests that incorporating linkage results from large multiplex families might greatly increase the efficiency of sequencing to detect trait-associated alleles in complex disease...
  3. pmc Comprehensive search for Alzheimer disease susceptibility loci in the APOE region
    Gyungah Jun
    Department of Medicine Biomedical Genetics, Boston University Schools of Medicine and Public Health, Boston, MA, USA
    Arch Neurol 69:1270-9. 2012
    ....
  4. pmc Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
    Margaux A Morrison
    Ocular Molecular Genetics Institute, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA, USA
    Hum Genomics 5:538-68. 2011
    ..These data not only extend previous biological studies in the AMD field, but further emphasise common antecedents between several disorders with an inflammatory/immunogenic component such as cardiovascular disease, cancer and AMD...
  5. pmc Multiple loci influencing hippocampal degeneration identified by genome scan
    Scott A Melville
    Department of Medicine, Boston University School of Medicine, MA, USA
    Ann Neurol 72:65-75. 2012
    ..We conducted a 2-stage GWAS for AD-related quantitative measures of hippocampal volume (HV), total cerebral volume (TCV), and white matter hyperintensities (WMH)...
  6. doi request reprint A search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways
    Mark W Logue
    Department of Medicine Biomedical Genetics, Boston University School of Medicine, Boston, MA, USA Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    Neurobiol Aging 35:1510.e7-18. 2014
    ..34, OR = 0.89, p = 1.17 × 10(-5)), which is a member of the atherosclerosis signaling and the LXR/RXR activation pathways. Our results suggest that AMD and AD share genetic mechanisms...
  7. pmc Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology
    Gyungah Jun
    Medicine Biomedical Genetics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 6:e25775. 2011
    ..These findings suggest that distinct ROBO1 variants may influence the risk of wet and dry AMD, and the effects of ROBO1 on AMD risk may be modulated by RORA variants...
  8. pmc Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes
    Gyungah Jun
    Department of Medicine, Boston University, USA
    Arch Neurol 67:1473-84. 2010
    ..To determine whether genotypes at CLU, PICALM, and CR1 confer risk for Alzheimer disease (AD) and whether risk for AD associated with these genes is influenced by apolipoprotein E (APOE) genotypes...