Research Topics
Species | Robert M JosephSummaryAffiliation: Boston University Country: USA Publications
Research Grants
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Detail Information
Publications
Cognitive profiles and social-communicative functioning in children with autism spectrum disorderRobert M Joseph
Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
J Child Psychol Psychiatry 43:807-21. 2002....
Self-ordered pointing in children with autism: failure to use verbal mediation in the service of working memory?Robert M Joseph
Boston University School of Medicine, Department of Anatomy and Neurobiology, 715 Albany St, L 814, Boston, MA 02118, USA
Neuropsychologia 43:1400-11. 2005..The findings are discussed in terms of possible autistic impairments in episodic memory as well as working memory...- Executive dysfunction and its relation to language ability in verbal school-age children with autismRobert M Joseph
Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
Dev Neuropsychol 27:361-78. 2005..This pattern of findings suggest that executive dysfunction in autism is not directly related to language impairment per se but rather involves an executive failure to use of language for self-regulation... 
Why is visual search superior in autism spectrum disorder?Robert M Joseph
Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
Dev Sci 12:1083-96. 2009....- The relationship of theory of mind and executive functions to symptom type and severity in children with autismRobert M Joseph
Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
Dev Psychopathol 16:137-55. 2004.... - Affective response to eye contact and face recognition ability in children with ASDRobert M Joseph
Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
J Int Neuropsychol Soc 14:947-55. 2008..There was no association between face recognition accuracy and SCRs to gaze in the TD group. These findings suggest that autonomic reactivity to eye contact may interfere with face identity processing in some children with ASD... - Holistic and part-based face recognition in children with autismRobert M Joseph
Department of Anatomy and Neurobiology, Boston University School of Medicine, Massachusetts 02118, USA
J Child Psychol Psychiatry 44:529-42. 2003..Although many researchers have suggested that this impairment derives from a failure of holistic face processing and a tendency to represent and encode faces on a part-by-part basis, this hypothesis has not been tested directly... - Impaired prioritization of novel onset stimuli in autism spectrum disorderBrandon Keehn
Boston University School of Medicine, Boston, MA 02118, USA
J Child Psychol Psychiatry 49:1296-303. 2008..Recent evidence suggests that individuals with ASD may be specifically impaired in attentional prioritization of novel onsets... - Reduced cognitive control of response inhibition by the anterior cingulate cortex in autism spectrum disordersYigal Agam
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02215, USA
Neuroimage 52:336-47. 2010..More generally, our findings suggest reduced cognitive control over behavior by the dACC in ASD... - Model syndromes for investigating social cognitive and affective neuroscience: a comparison of Autism and Williams syndromeHelen Tager-Flusberg
Boston University School of Medicine, Boston, MA 02118, USA
Soc Cogn Affect Neurosci 1:175-82. 2006..The article concludes with a discussion of how the social phenotypes of both syndromes may be characterized by impaired connectivity between the amygdala and other critical regions in the 'social brain'... - Disconnectivity of the cortical ocular motor control network in autism spectrum disordersTal Kenet
Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
Neuroimage 61:1226-34. 2012..The failure in the ASD group to increase alpha band coherence with increasing task demand may reflect deficient top-down recruitment of additional neural resources in preparation to perform a difficult task... - People with Williams syndrome process faces holisticallyHelen Tager-Flusberg
Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
Cognition 89:11-24. 2003..These findings contradict earlier reports in the literature that people with Williams syndrome process faces abnormally... - Brief report: developmental change in theory of mind abilities in children with autismShelly Steele
Boston University School of Medicine, Boston, Massachusetts 02118, USA
J Autism Dev Disord 33:461-7. 2003..g., moral judgment) mental state understanding. Both group and individual data indicated significant developmental improvement in theory of mind ability, which was primarily related to the children's language abilities... - A genome-wide linkage and association scan reveals novel loci for autismLauren A Weiss
Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Nature 461:802-8. 2009..The linkage regions reported here provide targets for rare variation screening whereas the discovery of a single novel association demonstrates the action of common variants... - Local and long-range functional connectivity is reduced in concert in autism spectrum disordersSheraz Khan
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
Proc Natl Acad Sci U S A 110:3107-12. 2013..These results suggest that failure to entrain neuronal assemblies fully both within and across cortical regions may be characteristic of ASD... - Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD)Katharine N Thakkar
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02215, USA
Brain 131:2464-78. 2008..Illuminating the mechanisms and clinical significance of abnormal response monitoring in ASD represents a fruitful avenue for further research... - Identifying autism loci and genes by tracing recent shared ancestryEric M Morrow
Division of Genetics, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Science 321:218-23. 2008.... - Identifying neurocognitive phenotypes in autismHelen Tager-Flusberg
Laboratory of Developmental Cognitive Neuroscience, Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street L 814, Boston, MA 02118, USA
Philos Trans R Soc Lond B Biol Sci 358:303-14. 2003..The implications for genetic and neurobiological studies of these subgroups are discussed, with special reference to evidence relating these cognitive phenotypes to volumetric studies of brain size and organization in autism... - Using whole-exome sequencing to identify inherited causes of autismTimothy W Yu
Division of Genetics, Department of Medicine, Boston Children s Hospital, Boston, MA 02115, USA
Neuron 77:259-73. 2013..Our study shows the utility of WES for identifying specific genetic conditions not clinically suspected and the importance of partial loss of gene function in ASDs... - Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autismIgor Splawski
Department of Cardiology, Children s Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02115, USA
Cell 119:19-31. 2004..These discoveries establish the importance of Ca(V)1.2 in human physiology and development and implicate Ca(2+) signaling in autism... - Abnormal activation of the social brain during face perception in autismNouchine Hadjikhani
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
Hum Brain Mapp 28:441-9. 2007..These patterns suggest that areas belonging to the mirror neuron system are involved in the face-processing disturbances in ASD... - Activation of the fusiform gyrus when individuals with autism spectrum disorder view facesNouchine Hadjikhani
Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Neuroimage 22:1141-50. 2004.... - Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the Collaborative Programs of Excellence in Autism networkSally Ozonoff
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA
J Autism Dev Disord 34:139-50. 2004.... - Early visual cortex organization in autism: an fMRI studyNouchine Hadjikhani
Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Bldg 36, First Street, Room 417, Charlestown, MA 02129, USA
Neuroreport 15:267-70. 2004..We conclude that the differences observed in the visual capacities of individuals with autism are likely to arise from higher-level cognitive areas and functions, and are the result of top-down processes... - Brief report: cognitive correlates of enlarged head circumference in children with autismCurtis K Deutsch
Eunice Kennedy Shriver Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA
J Autism Dev Disord 33:209-15. 2003..This convergence of physical and cognitive features suggests a possible etiologically significant subtype of autism... - Anatomical differences in the mirror neuron system and social cognition network in autismNouchine Hadjikhani
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Cereb Cortex 16:1276-82. 2006..These findings suggest that the social and emotional deficits characteristic of autism may reflect abnormal thinning of the MNS and the broader network of cortical areas subserving social cognition...
Research Grants
- Neural Substrates of Gaze and Face Processing in AutismRobert Joseph; Fiscal Year: 2007..Together, the training and research will provide the expertise and pilot data that will allow the candidate to prepare independent R01 applications near the completion of the training period. ..