Robert M Joseph

Summary

Affiliation: Boston University
Country: USA

Publications

  1. doi request reprint Structural asymmetries of language-related gray and white matter and their relationship to language function in young children with ASD
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 72 E Concord St, L 816, Boston, MA, 02118, USA
    Brain Imaging Behav 8:60-72. 2014
  2. doi request reprint Why is visual search superior in autism spectrum disorder?
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Dev Sci 12:1083-96. 2009
  3. doi request reprint Affective response to eye contact and face recognition ability in children with ASD
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Int Neuropsychol Soc 14:947-55. 2008
  4. pmc Cognitive profiles and social-communicative functioning in children with autism spectrum disorder
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
    J Child Psychol Psychiatry 43:807-21. 2002
  5. ncbi request reprint Self-ordered pointing in children with autism: failure to use verbal mediation in the service of working memory?
    Robert M Joseph
    Boston University School of Medicine, Department of Anatomy and Neurobiology, 715 Albany St, L 814, Boston, MA 02118, USA
    Neuropsychologia 43:1400-11. 2005
  6. pmc Executive dysfunction and its relation to language ability in verbal school-age children with autism
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
    Dev Neuropsychol 27:361-78. 2005
  7. pmc The relationship of theory of mind and executive functions to symptom type and severity in children with autism
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
    Dev Psychopathol 16:137-55. 2004
  8. ncbi request reprint Holistic and part-based face recognition in children with autism
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Massachusetts 02118, USA
    J Child Psychol Psychiatry 44:529-42. 2003
  9. doi request reprint Impaired prioritization of novel onset stimuli in autism spectrum disorder
    Brandon Keehn
    Boston University School of Medicine, Boston, MA 02118, USA
    J Child Psychol Psychiatry 49:1296-303. 2008
  10. pmc Model syndromes for investigating social cognitive and affective neuroscience: a comparison of Autism and Williams syndrome
    Helen Tager-Flusberg
    Boston University School of Medicine, Boston, MA 02118, USA
    Soc Cogn Affect Neurosci 1:175-82. 2006

Research Grants

Detail Information

Publications28

  1. doi request reprint Structural asymmetries of language-related gray and white matter and their relationship to language function in young children with ASD
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, 72 E Concord St, L 816, Boston, MA, 02118, USA
    Brain Imaging Behav 8:60-72. 2014
    ....
  2. doi request reprint Why is visual search superior in autism spectrum disorder?
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Dev Sci 12:1083-96. 2009
    ....
  3. doi request reprint Affective response to eye contact and face recognition ability in children with ASD
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Int Neuropsychol Soc 14:947-55. 2008
    ..There was no association between face recognition accuracy and SCRs to gaze in the TD group. These findings suggest that autonomic reactivity to eye contact may interfere with face identity processing in some children with ASD...
  4. pmc Cognitive profiles and social-communicative functioning in children with autism spectrum disorder
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
    J Child Psychol Psychiatry 43:807-21. 2002
    ....
  5. ncbi request reprint Self-ordered pointing in children with autism: failure to use verbal mediation in the service of working memory?
    Robert M Joseph
    Boston University School of Medicine, Department of Anatomy and Neurobiology, 715 Albany St, L 814, Boston, MA 02118, USA
    Neuropsychologia 43:1400-11. 2005
    ..The findings are discussed in terms of possible autistic impairments in episodic memory as well as working memory...
  6. pmc Executive dysfunction and its relation to language ability in verbal school-age children with autism
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
    Dev Neuropsychol 27:361-78. 2005
    ..This pattern of findings suggest that executive dysfunction in autism is not directly related to language impairment per se but rather involves an executive failure to use of language for self-regulation...
  7. pmc The relationship of theory of mind and executive functions to symptom type and severity in children with autism
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
    Dev Psychopathol 16:137-55. 2004
    ....
  8. ncbi request reprint Holistic and part-based face recognition in children with autism
    Robert M Joseph
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Massachusetts 02118, USA
    J Child Psychol Psychiatry 44:529-42. 2003
    ..Although many researchers have suggested that this impairment derives from a failure of holistic face processing and a tendency to represent and encode faces on a part-by-part basis, this hypothesis has not been tested directly...
  9. doi request reprint Impaired prioritization of novel onset stimuli in autism spectrum disorder
    Brandon Keehn
    Boston University School of Medicine, Boston, MA 02118, USA
    J Child Psychol Psychiatry 49:1296-303. 2008
    ..Recent evidence suggests that individuals with ASD may be specifically impaired in attentional prioritization of novel onsets...
  10. pmc Model syndromes for investigating social cognitive and affective neuroscience: a comparison of Autism and Williams syndrome
    Helen Tager-Flusberg
    Boston University School of Medicine, Boston, MA 02118, USA
    Soc Cogn Affect Neurosci 1:175-82. 2006
    ..The article concludes with a discussion of how the social phenotypes of both syndromes may be characterized by impaired connectivity between the amygdala and other critical regions in the 'social brain'...
  11. pmc Reduced cognitive control of response inhibition by the anterior cingulate cortex in autism spectrum disorders
    Yigal Agam
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02215, USA
    Neuroimage 52:336-47. 2010
    ..More generally, our findings suggest reduced cognitive control over behavior by the dACC in ASD...
  12. pmc Disconnectivity of the cortical ocular motor control network in autism spectrum disorders
    Tal Kenet
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Neuroimage 61:1226-34. 2012
    ..The failure in the ASD group to increase alpha band coherence with increasing task demand may reflect deficient top-down recruitment of additional neural resources in preparation to perform a difficult task...
  13. pmc Body expressions of emotion do not trigger fear contagion in autism spectrum disorder
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    Soc Cogn Affect Neurosci 4:70-8. 2009
    ..Our data suggest that emotion perception deficits in ASD may be due to compromised processing of the emotional component of observed actions...
  14. ncbi request reprint Brief report: developmental change in theory of mind abilities in children with autism
    Shelly Steele
    Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Autism Dev Disord 33:461-7. 2003
    ..g., moral judgment) mental state understanding. Both group and individual data indicated significant developmental improvement in theory of mind ability, which was primarily related to the children's language abilities...
  15. ncbi request reprint People with Williams syndrome process faces holistically
    Helen Tager-Flusberg
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
    Cognition 89:11-24. 2003
    ..These findings contradict earlier reports in the literature that people with Williams syndrome process faces abnormally...
  16. pmc A genome-wide linkage and association scan reveals novel loci for autism
    Lauren A Weiss
    Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 461:802-8. 2009
    ..The linkage regions reported here provide targets for rare variation screening whereas the discovery of a single novel association demonstrates the action of common variants...
  17. pmc Local and long-range functional connectivity is reduced in concert in autism spectrum disorders
    Sheraz Khan
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Proc Natl Acad Sci U S A 110:3107-12. 2013
    ..These results suggest that failure to entrain neuronal assemblies fully both within and across cortical regions may be characteristic of ASD...
  18. pmc Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD)
    Katharine N Thakkar
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02215, USA
    Brain 131:2464-78. 2008
    ..Illuminating the mechanisms and clinical significance of abnormal response monitoring in ASD represents a fruitful avenue for further research...
  19. pmc Identifying neurocognitive phenotypes in autism
    Helen Tager-Flusberg
    Laboratory of Developmental Cognitive Neuroscience, Department of Anatomy and Neurobiology, Boston University School of Medicine, 715 Albany Street L 814, Boston, MA 02118, USA
    Philos Trans R Soc Lond B Biol Sci 358:303-14. 2003
    ..The implications for genetic and neurobiological studies of these subgroups are discussed, with special reference to evidence relating these cognitive phenotypes to volumetric studies of brain size and organization in autism...
  20. pmc Identifying autism loci and genes by tracing recent shared ancestry
    Eric M Morrow
    Division of Genetics, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Science 321:218-23. 2008
    ....
  21. pmc Using whole-exome sequencing to identify inherited causes of autism
    Timothy W Yu
    Division of Genetics, Department of Medicine, Boston Children s Hospital, Boston, MA 02115, USA
    Neuron 77:259-73. 2013
    ..Our study shows the utility of WES for identifying specific genetic conditions not clinically suspected and the importance of partial loss of gene function in ASDs...
  22. ncbi request reprint Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
    Igor Splawski
    Department of Cardiology, Children s Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02115, USA
    Cell 119:19-31. 2004
    ..These discoveries establish the importance of Ca(V)1.2 in human physiology and development and implicate Ca(2+) signaling in autism...
  23. ncbi request reprint Early visual cortex organization in autism: an fMRI study
    Nouchine Hadjikhani
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Bldg 36, First Street, Room 417, Charlestown, MA 02129, USA
    Neuroreport 15:267-70. 2004
    ..We conclude that the differences observed in the visual capacities of individuals with autism are likely to arise from higher-level cognitive areas and functions, and are the result of top-down processes...
  24. ncbi request reprint Brief report: cognitive correlates of enlarged head circumference in children with autism
    Curtis K Deutsch
    Eunice Kennedy Shriver Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    J Autism Dev Disord 33:209-15. 2003
    ..This convergence of physical and cognitive features suggests a possible etiologically significant subtype of autism...
  25. ncbi request reprint Activation of the fusiform gyrus when individuals with autism spectrum disorder view faces
    Nouchine Hadjikhani
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Neuroimage 22:1141-50. 2004
    ....
  26. ncbi request reprint Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the Collaborative Programs of Excellence in Autism network
    Sally Ozonoff
    Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA
    J Autism Dev Disord 34:139-50. 2004
    ....
  27. ncbi request reprint Abnormal activation of the social brain during face perception in autism
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Hum Brain Mapp 28:441-9. 2007
    ..These patterns suggest that areas belonging to the mirror neuron system are involved in the face-processing disturbances in ASD...
  28. ncbi request reprint Anatomical differences in the mirror neuron system and social cognition network in autism
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Cereb Cortex 16:1276-82. 2006
    ..These findings suggest that the social and emotional deficits characteristic of autism may reflect abnormal thinning of the MNS and the broader network of cortical areas subserving social cognition...

Research Grants2

  1. Neural Substrates of Gaze and Face Processing in Autism
    Robert Joseph; Fiscal Year: 2007
    ..Together, the training and research will provide the expertise and pilot data that will allow the candidate to prepare independent R01 applications near the completion of the training period. ..