Research Topics
| Hershel JickSummaryAffiliation: Boston University Country: USA Publications
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Detail Information
Publications
Lipid-lowering drugs and the risk of depression and suicidal behaviorChen-Chang Yang
Department of Internal Medicine, Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
Arch Intern Med 163:1926-32. 2003....
Epidemiology and possible causes of autismHershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 23:1524-30. 2003....
In vitro fertilization and childhood retinoblastomaBrian D Bradbury
The Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, 11 Muzzey Street, Lexington, MA 02421, USA
Br J Clin Pharmacol 58:209-11. 2004..To estimate the frequency of childhood retinoblastoma among children conceived by in vitro fertilization (IVF)...
Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research DatabaseStefan Russmann
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Br J Clin Pharmacol 60:76-82. 2005..To provide additional quantification of the risk of flucloxacillin-related liver disease and to describe time trends in flucloxacillin prescribing in the UK...
The contraceptive patch in relation to ischemic stroke and acute myocardial infarctionSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 27:218-20. 2007..To compare rates of stroke and acute myocardial infarction in users of the Ortho EVRA contraceptive patch with these rates in users of norgestimate-containing oral contraceptives (OCs) with 35 microg of ethinyl estradiol...
Comparison of prescription drug costs in the United States and the United Kingdom, part 2: proton pump inhibitorsHershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Boston University School of Medicine, 11 Muzzey Street, Lexington, MA 02421, USA
Pharmacotherapy 32:489-92. 2012..To compare the annual cost of proton pump inhibitors (PPIs) in the United States and in the United Kingdom...
Comparison of prescription drug costs in the United States and the United Kingdom, Part 1: statinsHershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 32:1-6. 2012..To compare the annual cost of statins in the United States and in the United Kingdom...
Risk of venous thromboembolism among users of third generation oral contraceptives compared with users of oral contraceptives with levonorgestrel before and after 1995: cohort and case-control analysisH Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
BMJ 321:1190-5. 2000..To compare the risk of idiopathic venous thromboembolism among women taking third generation oral contraceptives (with gestodene or desogestrel) with that among women taking oral contraceptives with levonorgestrel...
Rate of suicide in patients taking montelukastHershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 29:165-6. 2009..To estimate the rate of suicide in patients taking montelukast...
The origin and spread of a mumps epidemic: United kingdom, 2003-2006Hershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Epidemiology 20:656-61. 2009..The origin and spread was mapped in 350 general practices that used office computers to contribute comprehensive medical information on approximately 3 million patients to the General Practice Research Database (GPRD)...
Incidence and prevalence of drug-treated attention deficit disorder among boys in the UKHershel Jick
Boston University School of Medicine, Boston University, Lexington, MA, USA
Br J Gen Pract 54:345-7. 2004..Since no quantitative data on the incidence and prevalence of drug-treated ADD are available in the UK, we used the general practice research database (GPRD) to obtain such information...
Measles in the United Kingdom 1990-2008 and the effectiveness of measles vaccinesHershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, 11 Muzzey Street, Lexington, MA 02421, USA
Vaccine 28:4588-92. 2010..Since 1996, the incidence of measles has fallen by more than 80%. Prior measles vaccination is highly effective and has substantially reduced the risk of measles...
Effectiveness of influenza vaccination in the United kingdom, 1996-2007Hershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 30:1199-206. 2010..To estimate the effectiveness of influenza vaccination in people in the United Kingdom at low risk for influenza during an 11-year period from July 1996-June 2007...
Nonsteroidal antiinflammatory drugs and acute myocardial infarction in patients with no major risk factorsHershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 26:1379-87. 2006..To assess the risk of long-term use of five nonsteroidal antiinflammatory drugs (NSAIDs)--rofecoxib, celecoxib, ibuprofen, naproxen, and diclofenac--in relation to acute myocardial infarction...
Antidepressants and the risk of suicidal behaviorsHershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Mass 02421, USA
JAMA 292:338-43. 2004..The use of such drugs among teenagers has been of particular concern...
Risk of nonfatal venous thromboembolism with oral contraceptives containing norgestimate or desogestrel compared with oral contraceptives containing levonorgestrelSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Contraception 73:566-70. 2006..Estimates of the risk for VTE among users of norgestimate-containing OCs compared to other OCs, however, are lacking...
Further results on the risk of nonfatal venous thromboembolism in users of the contraceptive transdermal patch compared to users of oral contraceptives containing norgestimate and 35 microg of ethinyl estradiolSusan Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Contraception 76:4-7. 2007....
The risk of unintended pregnancies in users of the contraceptive patch compared to users of oral contraceptives in the UK General Practice Research DatabaseSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Contraception 80:142-51. 2009..The transdermal contraceptive patch EVRA has been marketed since 2002 as an alternative to oral contraceptives (OCs), but large follow-up studies of effectiveness are lacking...
Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patchSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Contraception 74:290-2. 2006..It has been suggested that the risk for cerebral venous sinus thrombosis (CVST) may be greater among users of the contraceptive patch than among users of oral contraceptives (OCs)...
Diclofenac and acute myocardial infarction in patients with no major risk factorsSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Br J Clin Pharmacol 64:662-7. 2007..To explore further a recent finding that long-term users of diclofenac are at increased risk of acute myocardial infarction (AMI) similar to users of rofecoxib and celecoxib...
Validity of the general practice research databaseSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 23:686-9. 2003..We reviewed evidence related to the validity of the GPRD. Specifically, with our extensive experience with this automated database, we evaluated the quality and completeness of the data that it contains...
Antibiotics and the risk of breast cancerJames A Kaye
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA, USA
Epidemiology 16:688-90. 2005..Two recent studies found a positive association between antibiotic use and the risk of breast cancer...
Risk of nonfatal venous thromboembolism in women using a contraceptive transdermal patch and oral contraceptives containing norgestimate and 35 microg of ethinyl estradiolSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Contraception 73:223-8. 2006..There is concern that a new transdermal contraceptive patch containing ethinyl estradiol (EE) and the progestin norelgestromin increases the risk for venous thromboembolism (VTE) compared to previously marketed oral contraceptives (OCs)...
Clinical risk factors for venous thromboembolus in users of the combined oral contraceptive pillCorri Black
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, 11 Muzzey Street, Lexington, MA 02421, USA
Br J Clin Pharmacol 53:637-40. 2002....
Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research DatabaseCorri Black
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, MA 02421, USA
BMJ 325:419-21. 2002..To assess whether children with autism are more likely to have a history of gastrointestinal disorders than children without autism...
Incidence of erectile dysfunction and characteristics of patients before and after the introduction of sildenafil in the United Kingdom: cross sectional study with comparison patientsJames A Kaye
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, 11 Muzzey Street, Lexington, MA 02421, USA
BMJ 326:424-5. 2003
Postmenopausal estrogen-containing hormone therapy and the risk of breast cancerSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts, USA
Obstet Gynecol 113:74-80. 2009..To investigate the relation of various estrogen-containing hormone therapies to the risk of breast cancer, emphasizing the use of the combination of estrogen and testosterone...
Comparison of prescription drug costs in the United States and the United kingdom, part 3: methylphenidateHershel Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts
Pharmacotherapy 32:970-3. 2012..To compare the annual cost of methylphenidate in the United States and the United Kingdom...
A population-based study of the incidence, cause, and severity of anaphylaxis in the United KingdomMichael M Peng
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA 02421, USA
Arch Intern Med 164:317-9. 2004..The most common causes were insect stings and oral medicines. CONCLUSION: Anaphylaxis is an uncommon illness that has multiple causes and can be life-threatening...
Changes in antipsychotic drug prescribing by general practitioners in the United Kingdom from 1991 to 2000: a population-based observational studyJames A Kaye
Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA
Br J Clin Pharmacol 56:569-75. 2003..It will be of interest to see whether the use of thioridazine, which was the most widely prescribed antipsychotic during 1991-2000, decreases during the next decade in response to the recent CSM recommendation...
Proton pump inhibitor use and risk of hip fractures in patients without major risk factorsJames A Kaye
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA, USA
Pharmacotherapy 28:951-9. 2008..To estimate the relative risk of hip fracture associated with proton pump inhibitor (PPI) use in a population without major risk factors...
Etiology and frequency of rhabdomyolysisCorri Black
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, Massachusetts 02421, USA
Pharmacotherapy 22:1524-6. 2002..Of those, only one patient was taking a statin and fibrate concurrently, out of almost 3000 concurrent users. The free-text comments field in the GPRD helped to identify patients with rhabdomyolysis...
Incident diabetes associated with antipsychotic use in the United Kingdom general practice research databaseCynthia J Kornegay
Office of Drug Safety, Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD, USA
J Clin Psychiatry 63:758-62. 2002..Recent reports suggest an association between antipsychotic use and development or exacerbation of diabetes. This study evaluated the risk of incident diabetes associated with the use of atypical and conventional antipsychotics...
Use of nonsteroidal anti-inflammatory drugs and the risk of first-time acute myocardial infarctionRaymond G Schlienger
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital, Basel, Switzerland
Br J Clin Pharmacol 54:327-32. 2002..CONCLUSIONS: Our findings indicate that current NSAID exposure in patients free of diagnosed cardiovascular or metabolic conditions predisposing to cardiovascular diseases does not decrease the risk of AMI...
Association between acetaminophen or nonsteroidal antiinflammatory drugs and risk of developing ovarian, breast, or colon cancerChristoph R Meier
Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Switzerland
Pharmacotherapy 22:303-9. 2002..To explore the association between exposure to acetaminophen (paracetamol) or nonsteroidal antiinflammatory drugs (NSAIDs) and risk of developing ovarian, breast, or colon cancer...
Use of thiazolidinediones and fracture riskChristian Meier
Division of Endocrinology, Diabetes, and Clinical Nutrition, University Hospital Basel, Hebelstrasse 2, CH 4031 Basel, Switzerland
Arch Intern Med 168:820-5. 2008..Thiazolidinediones may adversely affect the skeleton owing to decreased bone formation and accelerated bone loss...
Changes in risk of autism in the U.K. for birth cohorts 1990-1998Hershel Jick
Epidemiology 14:630-2. 2003
Statins and the risk of idiopathic venous thromboembolismChen-Chang Yang
Department of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC
Br J Clin Pharmacol 53:101-5. 2002..9 (0.4, 2.0) in the follow-up analysis, and were 1.1 (0.3, 4.3), 3.7 (0.6, 24.1), 2.0 (0.3, 11.6), and 0.4 (0.2, 1.2) in the case-control analysis. CONCLUSIONS: Current statin use was not associated with a reduced risk of idiopathic VTE...
Association between body mass index and liver disorders: an epidemiological studyChristoph R Meier
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, Department of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
J Hepatol 37:741-7. 2002..Cross-sectional studies showed an association between obesity and liver disorders. Information on incidence rates from epidemiological studies is scarce...
Effect of rheumatoid arthritis or systemic lupus erythematosus on the risk of first-time acute myocardial infarctionLorenz M Fischer
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Am J Cardiol 93:198-200. 2004..23 to 1.76), and in subjects with both RA and diagnosed hyperlipidemia, the OR was 7.12 (95% CI 4.16 to 12.18). The risk associated with SLE was 2.67 (95% CI 1.34 to 5.34). These results underline that RA and SLE increase the risk of AMI...
Cigarette smoking and the progression of multiple sclerosisMiguel A Hernán
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Brain 128:1461-5. 2005....
Cardiovascular safety of cyclo-oxygenase-2 inhibitorsSusan S Jick
Lancet 369:555-6; author reply 556. 2007
Statins and the risk of pneumonia: a population-based, nested case-control studyRaymond G Schlienger
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Pharmacotherapy 27:325-32. 2007..To determine if the use of statins affects pneumonia-related outpatient visits, hospitalizations with survival, and deaths...
Time trends in eating disorder incidenceLaura Currin
Section of Eating Disorders, Institute of Psychiatry, Mental Health Department, St George s Hospital Medical School, London, UK
Br J Psychiatry 186:132-5. 2005..During the years 1988-1993 the primary care incidence of anorexia nervosa in the UK remained stable, but the incidence of bulimia nervosa increased threefold...
Cesarean delivery in the United Kingdom: time trends in the general practice research databaseCorri Black
Department of Public Health, University of Aberdeen, Scotland
Obstet Gynecol 106:151-5. 2005..To estimate recent temporal trends in delivery by cesarean during the past decade and the proportion of vaginal deliveries after prior caesarean in the United Kingdom...
Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarctionRaymond G Schlienger
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Drug Saf 27:1157-65. 2004..42 (95% CI 1.02, 1.97; p=0.04). CONCLUSION: The present analysis provides further evidence that the current use of SSRIs is associated with a slightly decreased risk for AMI...
Recent use of oral contraceptives and the risk of multiple sclerosisAlvaro Alonso
Department of Epidemiology, Harvard School of Public Health, Brigham and Women s Hospital, Boston, MA 02115, USA
Arch Neurol 62:1362-5. 2005..Exogenous estrogens affect the onset and clinical course of experimental allergic encephalomyelitis. Oral contraceptives, a frequent source of exogenous estrogens in humans, could have a role in the development of multiple sclerosis (MS)...
Incidence of autism over timeHershel Jick
Epidemiology 17:120-1. 2006
Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective studyMiguel A Hernán
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Neurology 63:838-42. 2004..A potential link between the recombinant hepatitis B vaccine and an increased risk of multiple sclerosis (MS) has been evaluated in several studies, but some of them have substantial methodologic limitations...
Antibiotic use and risk of multiple sclerosisAlvaro Alonso
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Am J Epidemiol 163:997-1002. 2006..pneumoniae was not associated with a decreased risk of short-term multiple sclerosis. The observed lower risk of multiple sclerosis for penicillin users needs to be confirmed in other populations...
Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarctionLorenz M Fischer
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital, Basel, Switzerland
Pharmacotherapy 25:503-10. 2005..We found no evidence for a reduced cardioprotective effect of aspirin with concomitant NSAID use...
Autism and DPT vaccination in the United KingdomHershel Jick
N Engl J Med 350:2722-3. 2004
MMR vaccine and idiopathic thrombocytopaenic purpuraCorri Black
Department of Public Health, Aberdeen University, Aberdeen, UK
Br J Clin Pharmacol 55:107-11. 2003....
Using prescription claims data for drugs available over-the-counter (OTC)Marianne Ulcickas Yood
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
Pharmacoepidemiol Drug Saf 16:961-8. 2007..The purpose of this study is to quantify the effect of misclassification of OTC use in research that uses prescription claims data as the sole source of exposure information...
Discontinuation of nonsteroidal anti-inflammatory drug therapy and risk of acute myocardial infarctionLorenz M Fischer
Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
Arch Intern Med 164:2472-6. 2004..07 [95% CI, 0.96-1.19] and 1.05 [95% CI, 0.99-1.12], respectively). CONCLUSION: Our findings suggest that the risk of AMI is increased during several weeks after the cessation of NSAID therapy...
Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working GroupPhil Lieberman
Division of Allergy Immunology, Department of Medicine, University of Tennessee College of Medicine, Germantown, Tennessee, USA
Ann Allergy Asthma Immunol 97:596-602. 2006..To improve understanding of the epidemiology of anaphylaxis...
