Tien Hsu

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms
    T Hsu
    Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Oncogene 31:2247-57. 2012
  2. pmc NME genes in epithelial morphogenesis
    Tien Hsu
    Department of Medicine, Boston University School of Medicine, 650 Albany St, Room 440, Boston, MA 02118, USA
    Naunyn Schmiedebergs Arch Pharmacol 384:363-72. 2011
  3. pmc Systemic VHL gene functions and the VHL disease
    Hannah L Bader
    Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    FEBS Lett 586:1562-9. 2012

Collaborators

  • Hannah L Bader

Detail Information

Publications3

  1. pmc Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms
    T Hsu
    Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Oncogene 31:2247-57. 2012
    ..In this review, the studies performed in model organisms will be summarized and placed in context with existing clinical and in vitro data...
  2. pmc NME genes in epithelial morphogenesis
    Tien Hsu
    Department of Medicine, Boston University School of Medicine, 650 Albany St, Room 440, Boston, MA 02118, USA
    Naunyn Schmiedebergs Arch Pharmacol 384:363-72. 2011
    ..Such biphasic functions provide a plausible explanation for the documented anti-metastatic activity and the suspected oncogenic function. This review summarizes these recent findings and discusses their implications...
  3. pmc Systemic VHL gene functions and the VHL disease
    Hannah L Bader
    Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    FEBS Lett 586:1562-9. 2012
    ..As such, systemic functions of VHL likely play important roles in the development of VHL disease...

Research Grants13

  1. VHL and FGFR signaling in angiogenesis
    Tien Hsu; Fiscal Year: 2007
    ..Aim 4 will employ knockout mice to test the hypothesis that VHL heterozygous mutation in endothelial cells in the VHL disease patients play an important role in the disease' highly vascularized tumorigenic characteristics. ..
  2. Control of epithelial morphogenesis in Drosphila ovary
    Tien Hsu; Fiscal Year: 2006
    ..Aim 2: To determine the underlying mechanism of EGFR mislocalization in DVHL mutant. Aim 3: To analyze the role of Rac in linking integrin and DE-cadherin functions. Aim 4: To isolate additional DVHL and novel Awd interacting protein. ..
  3. SIGNALING MECHANISMS IN FOLLICLE CELL FATE DETERMINATION
    Tien Hsu; Fiscal Year: 2002
    ..abstract_text> ..